Gene

KWMTBOMO01184

Annotation

PREDICTED:_frizzled-4_[Bombyx_mori]

Location

Bomo_Chr3(+):4022740-4023834      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 1.558 PlasmaMembrane   Reliability : 2.059

CDS

ATGTTGTGCATTATAGCGATTCTGTTTACTATTTGCCACGTTCCGCGCGCCATCGCCGAGGCCTCCGTGCGGACGTGCGAACCCATTAAAGTGGCAATGTGCAAGAACATCGGCTACAACCAGACCGGTATGCCGAACTTGGCCCGGCACACCCTGCAAGCTGATGCCGATATCACGTTGCAAACATTCAGTCCGCTGGTCCAGTATGGCTGCTCTTCCCAGCTTCATTTGTTTCTGTGTTCGGTCTACGTTCCCATGTGTACGGATAAAGTGGCGCTGCCGATCGGGCCCTGTCGAGGACTGTGTGACAGTGTGCACGCCAGATGTTTCCCTGTGCTTCATGGTTTCGGATTTTCTTGGCCCCCGGAGCTAGATTGCACACTGTTTCCAGCGGAAAACAATCACGAACACATGTGTATGGAGGGGCCCGGCGAAAGAGCCCCACCGGTCGGGAGTATCCCGTTGAACGCAACGGGTGCGTGTAGGAGATTAATCAAACCAAACAGTTGGGTGTGGGTTAGAGGATCAGGCCGCTGCGCCCAGTTTTGTGATGCCGAAGTCCTGTGGGAAACTGGTGAACGCAGAGCGGCGGAAGTATGGCTCGCTACGTGGGCAGCATTAAGCTTTGCTTGCACTTTGGCAGCTGTCGCTGCGCAATTAGCATGCGGAGATCGCGGAGGAGCTGGAGAACGAGCACTAGTGCTAGTGGCTCTGTGCAGGTGTGCTGCAGCGGCTGGATGGGGCGTTCGCGCTGCTGCAGGTCGAGCTGCAGCCGGCTGCGCCAAGGACTCCACATCCCCGGCACGCATGCTTCTAGCACACGACGGACTTGCGAATCCAAATTGCGCTGTTGTGTTCTTGCTACTCTACTATTTCGGTCTTGCTGCATCAGTATGGTAA

Protein

MLCIIAILFTICHVPRAIAEASVRTCEPIKVAMCKNIGYNQTGMPNLARHTLQADADITLQTFSPLVQYGCSSQLHLFLCSVYVPMCTDKVALPIGPCRGLCDSVHARCFPVLHGFGFSWPPELDCTLFPAENNHEHMCMEGPGERAPPVGSIPLNATGACRRLIKPNSWVWVRGSGRCAQFCDAEVLWETGERRAAEVWLATWAALSFACTLAAVAAQLACGDRGGAGERALVLVALCRCAAAAGWGVRAAAGRAAAGCAKDSTSPARMLLAHDGLANPNCAVVFLLLYYFGLAASVW

Similarity

Belongs to the G-protein coupled receptor Fz/Smo family.

Uniprot

A0A2H1WHI0   A0A0L7LT04   A0A2W1BUH4   A0A0N1IPQ0   A0A194QH20   E0VTY7   + More
A0A067QI70   A0A2J7PDI9   A0A2P8ZKL4   A0A1B6DPR4   A0A1L8DK55   A0A1L8DJY3   A0A182RUR5   A0A182P689   A0A182INA5   A0A182QDI3   A0A182NGK4   A0A084VYM0   Q16Z40   A0A1S4FJE8   A0A0P6K0R9   A0A182MSR5   B0XJ68   A0A182TNP6   A0A182F5R0   A0A1B0GHY9   A0A2M3Z8P2   W5J2Z5   A0A182Y946   U5EVX7   Q7PWS3   A0A2M4BIR5   A0A2Y9D3G4   A0A2Y9D338   A0A1S4GZH6   A0A2Y9D1A0   A0A2Y9D0X8   A0A2M4ACJ2   A0A2M4BI20   A0A2M4BHQ9   A0A2M4DMA2   A0A2M4DM18   A0A2M4AB01   A0A2M4DM48   A0A182VU92   D6WXE3   A0A1W4XS35   A0A1J1IN81   V5GVY2   V4AZI8   K1PCJ3   A0A2K9RCH1   A0A1Y1NHG2   A0A1B6LGK1   G3W6F2   L8I683   W5P216   A0A2K6FKH4   A0A2Z6DTI3   A0A1A9XLT1   A0A1B0BS09   G7NBE7   A0A2K6A094   F6VFD0   M3YG22   A0A0M5J2S8   G3W6F3   F1MLJ8   A0A2Y9KE60   A0A3P4PK54   A0A1S3AMT0   U3IF46   H0X4W4   A0A2K6A0D6   E2RIL8   A0A2I3GWH4   R0JEY9   A0A2R9BZZ4   K7AZD4   A0A2Y9GSD1   A0A2U3YTI7   A0A2U3WX61   A0A2I2Y8P7   H0VQV3   D2HRQ0   A0A2K6BE62   A0A096MVT8   A0A2K5KR10   A0A2J8S696   A0A2K5HXU4  

Pubmed

26227816    28756777    26354079    20566863    24845553    29403074    + More
24438588    17510324    26999592    20920257    23761445    25244985    12364791    20966253    18362917    19820115    23254933    22992520    29337984    28004739    21709235    22751099    20809919    22002653    17495919    19393038    23749191    16341006    22722832    16136131    22398555    21993624    20010809   

EMBL

ODYU01008711    SOQ52525.1    JTDY01000193    KOB78361.1    KZ149958    PZC76430.1    + More
KQ460366    KPJ15617.1    KQ458860    KPJ04807.1    DS235777    EEB16843.1    KK853353    KDR08218.1    NEVH01026386    PNF14399.1    PYGN01000028    PSN57048.1    GEDC01016621    GEDC01009641    JAS20677.1    JAS27657.1    GFDF01007327    JAV06757.1    GFDF01007328    JAV06756.1    AXCN02002086    ATLV01018378    ATLV01018379    KE525231    KFB43064.1    CH477499    EAT39910.2    GDUN01000892    JAN95027.1    AXCM01006076    DS233443    EDS30031.1    AJWK01010438    AJWK01010439    AJWK01010440    AJWK01010441    AJWK01010442    AJWK01010443    AJWK01010444    GGFM01004114    MBW24865.1    ADMH02002160    ETN58191.1    GANO01003211    JAB56660.1    AAAB01008984    EAA14897.1    GGFJ01003753    MBW52894.1    APCN01003367    GGFK01005194    MBW38515.1    GGFJ01003568    MBW52709.1    GGFJ01003448    MBW52589.1    GGFL01014509    MBW78687.1    GGFL01014438    MBW78616.1    GGFK01004636    MBW37957.1    GGFL01014462    MBW78640.1    KQ971361    EFA09255.1    CVRI01000054    CRK99937.1    GALX01000152    JAB68314.1    KB201110    ESO99146.1    JH816921    EKC19233.1    MG711510    AUT31436.1    GEZM01002141    JAV97354.1    GEBQ01017152    JAT22825.1    AEFK01118862    AEFK01118863    JH882118    ELR50747.1    AMGL01060485    LC379618    BBD75255.1    JXJN01019440    CM001266    EHH23307.1    AEYP01058513    CP012528    ALC48374.1    CYRY02032577    VCX10185.1    ADON01125834    ADON01125835    ADON01125836    AAQR03000626    AAEX03012748    ADFV01110850    KB744255    EOA95541.1    AJFE02118662    AACZ04016352    GABC01005735    GABF01004552    GABD01009724    GABE01006250    JAA05603.1    JAA17593.1    JAA23376.1    JAA38489.1    CABD030080663    CABD030080664    CABD030080665    AAKN02037816    ACTA01010081    GL193232    EFB29124.1    AHZZ02007267    NDHI03003605    PNJ16278.1   

Proteomes

UP000037510    UP000053240    UP000053268    UP000009046    UP000027135    UP000235965    + More
UP000245037    UP000075900    UP000075885    UP000075880    UP000075886    UP000075884    UP000030765    UP000008820    UP000075883    UP000002320    UP000075902    UP000069272    UP000092461    UP000000673    UP000076408    UP000007062    UP000076407    UP000075903    UP000075882    UP000075840    UP000075920    UP000007266    UP000192223    UP000183832    UP000030746    UP000005408    UP000007648    UP000002356    UP000233160    UP000092443    UP000092460    UP000233140    UP000002280    UP000000715    UP000092553    UP000009136    UP000248482    UP000079721    UP000016666    UP000005225    UP000002254    UP000001073    UP000240080    UP000002277    UP000248481    UP000245341    UP000245340    UP000001519    UP000005447    UP000008912    UP000233120    UP000028761    UP000233060    UP000233080   

Pfam

PF01392   Fz        + More
PF01534   Frizzled

Interpro

IPR026551   FZD4        + More
IPR015526   Frizzled/SFRP       
IPR036790   Frizzled_dom_sf       
IPR020067   Frizzled_dom       
IPR000539   Frizzled/Smoothened_TM       
IPR017981   GPCR_2-like       
IPR041765   FZ4_CRD       
IPR026549   FZD10       

SUPFAM

SSF63501   SSF63501       

Gene 3D

1.10.2000.10    

CDD

cd07448  CRD_FZ4

ProteinModelPortal

A0A2H1WHI0   A0A0L7LT04   A0A2W1BUH4   A0A0N1IPQ0   A0A194QH20   E0VTY7   + More
A0A067QI70   A0A2J7PDI9   A0A2P8ZKL4   A0A1B6DPR4   A0A1L8DK55   A0A1L8DJY3   A0A182RUR5   A0A182P689   A0A182INA5   A0A182QDI3   A0A182NGK4   A0A084VYM0   Q16Z40   A0A1S4FJE8   A0A0P6K0R9   A0A182MSR5   B0XJ68   A0A182TNP6   A0A182F5R0   A0A1B0GHY9   A0A2M3Z8P2   W5J2Z5   A0A182Y946   U5EVX7   Q7PWS3   A0A2M4BIR5   A0A2Y9D3G4   A0A2Y9D338   A0A1S4GZH6   A0A2Y9D1A0   A0A2Y9D0X8   A0A2M4ACJ2   A0A2M4BI20   A0A2M4BHQ9   A0A2M4DMA2   A0A2M4DM18   A0A2M4AB01   A0A2M4DM48   A0A182VU92   D6WXE3   A0A1W4XS35   A0A1J1IN81   V5GVY2   V4AZI8   K1PCJ3   A0A2K9RCH1   A0A1Y1NHG2   A0A1B6LGK1   G3W6F2   L8I683   W5P216   A0A2K6FKH4   A0A2Z6DTI3   A0A1A9XLT1   A0A1B0BS09   G7NBE7   A0A2K6A094   F6VFD0   M3YG22   A0A0M5J2S8   G3W6F3   F1MLJ8   A0A2Y9KE60   A0A3P4PK54   A0A1S3AMT0   U3IF46   H0X4W4   A0A2K6A0D6   E2RIL8   A0A2I3GWH4   R0JEY9   A0A2R9BZZ4   K7AZD4   A0A2Y9GSD1   A0A2U3YTI7   A0A2U3WX61   A0A2I2Y8P7   H0VQV3   D2HRQ0   A0A2K6BE62   A0A096MVT8   A0A2K5KR10   A0A2J8S696   A0A2K5HXU4  

PDB

5BQE     E-value=4.35361e-47,     Score=473

KEGG

101742593    K02354 frizzled 4 | (RefSeq) frizzled-4

GO

GO:0007275   GO:0016020   GO:0042813   GO:0016021   GO:0060070   GO:0035567   GO:0017147   GO:0005886   GO:0061301   GO:0031987   GO:0030165   GO:0110135   GO:0043507   GO:0004896   GO:0001540   GO:0051091   GO:0045893   GO:0031625   GO:0042701   GO:0005911   GO:0007223   GO:1990830   GO:0010812   GO:0030425   GO:0009986   GO:0150012   GO:0035426   GO:0034446   GO:0061304   GO:0030947   GO:0046982   GO:0042803   GO:0098978   GO:0044877   GO:0007605   GO:0001570   GO:0019955   GO:0061299   GO:0016055   GO:0007166   GO:0005515   GO:0051287   GO:0006000   GO:0004553   GO:0005634   GO:0006334   GO:0003779  

PANTHER

PTHR11309:SF23   PTHR11309   PTHR11309:SF86  

SignalP

Position:   1 - 19,         Likelihood:  0.994115

 

 

Length:

299

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

49.75863

Exp number, first 60 AAs:

0.21419

Total prob of N-in:

0.37840

outside

1  -  275

TMhelix

276  -  298

inside

299  -  299

 

 

Pi

138.615402

Theta

160.410039

Tajima's D

-0.853185

CLR

212.442744

CSRT

0.165191740412979

Interpretation

Uncertain