Gene

KWMTBOMO01170  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007453

Annotation

Mn_superoxide_dismutase_[Bombyx_mori]

Location

Bomo_Chr3(-):3819784-3824525      View in EpiBrowser

Full name

Superoxide dismutase      

Location in the cell

Mitochondrial   Reliability : 2.93

CDS

ATGTCACAAAGGATTGGATCATTGATTCGAGTTGCCGGTGCTTCTCGCCAGAAGCATACTTTGCCAGAGCTTCCGTACGAGTACAATGCACTGGAGCCGGTCATTAGCCGTGAAATCATGAGTCTTCATCACAGCAAACATCACGCGACTTATATCAACAATCTAAACGTTGCTGAAGAGAAACTCGCACAGGCACAAGCTAAAGGTGATATCGACACCATTATCAACCTTGCACCAGCCTTGAAATTCAATGGTGGTGGTCACATCAACCACTCGATCTTTTGGCACAACCTGTCACCAAATGGTGGCAAGCCTTCTGATGTTCTCACCAAAGCCGTTGAGAAAGACTTTGGATCCTGGGATAACTTAAAGAATCAACTGTCGACAGCTTCTGTGGCAGTACAGGGCTCAGGCTGGGGTTGGCTTGGCTACAACAAACAAATGAAGAAATTGCAAATAGCTACATGCCAGAACCAGGATCCTCTGCAGGCCACCACTGGATTGGTCCCGCTCTTCGGAATCGATGTATGGGAGCACGCGTACTATCTTCAGTACAAGAACGTTCGTGCCGACTACGTGAAAGCTATTTTCGATGTAGCCAACTGGAATGATATATCTCAGAGATATGAAAAAGCGCTCAAGTGA

Protein

MSQRIGSLIRVAGASRQKHTLPELPYEYNALEPVISREIMSLHHSKHHATYINNLNVAEEKLAQAQAKGDIDTIINLAPALKFNGGGHINHSIFWHNLSPNGGKPSDVLTKAVEKDFGSWDNLKNQLSTASVAVQGSGWGWLGYNKQMKKLQIATCQNQDPLQATTGLVPLFGIDVWEHAYYLQYKNVRADYVKAIFDVANWNDISQRYEKALK

Description

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic Activity

2 H(+) + 2 superoxide = H2O2 + O2

Similarity

Belongs to the iron/manganese superoxide dismutase family.

Feature

chain  Superoxide dismutase

Uniprot

Q65Y02   H9JD56   A0A2Z4N450   A0A0H3WLT1   A0A2S0RQT9   A0A0N0PD16   + More
A0A2A4ISP3   A0A0K0KJP6   A5Z1R7   A0A2W1BXF6   A0A212EU89   A0A2S0RQQ5   S4P9M2   D1M6Z4   A1E9A8   A0A067RBP2   A0A2P0XIZ9   A0A0H3WJR5   A0A3G9D4G0   A2SUH5   A7UL75   T2FE54   Q3Y596   K7IT33   A0A232FL74   G0Z047   M9T285   M4QL80   E6YCY4   D3J1L2   A0A2J7PDG3   E6YCX8   E6YCY7   A0A0P4WJN8   I6VM78   B9VUA3   I3VPK0   Q9NB66   E6YCX7   A0A0C9RVL9   A0A2A3EJB2   E6YCY2   E6YCY0   E6YCY5   E6YCY3   E6YCX9   A0A088A1K0   S4S5N4   Q7YXM5   E6YCY9   A0A0L7QNL3   E6YCY1   E6YCY8   A0A154PPR8   E1ZX89   E2B9W8   A0A0C9R9C6   H1ZSY8   R7V502   E6YCY6   A0A3M6TVI6   D6WWA9   A0A026WLL5   T1G7C2   A0A166AJ53   H2B644   E9IG44   F8R8R3   A0A087UP78   A0A2B4RVE0   A0A2I2MNA6   E1CPV0   A0A1B6KIM9   A0A2I2MNA9   A0A2I2MNB0   B4JWP5   A0A0K0EMH0   C3YI11   A0A195C2Y0   A0A226DD29   A0A0K0F4D5   J9XY23   A0A090L504   A0A2I2MNA3   A0A1B0DF57   A0A1Y1LRX0   A0A1B6FT12   A0A158NW84   A7RHP7   A0A0N5C416   A0A2P6LDK6   R4WD37   W8C1Z3   A0A1B6ICS9   W4Z933   A0A1I7S0V0   A0A183FRG8   A0A3P7YB45   A0A1L3THW9   A0A096X914  

EC Number

1.15.1.1

Pubmed

19121390    26354079    28756777    22118469    23622113    24845553    + More
25700787    26760975    17097141    16621606    20075255    28648823    19835962    26394265    25366155    12769817    24269344    11932240    16139867    20798317    23254933    30382153    18362917    19820115    27387523    24508170    30249741    22062798    21282665    21565362    17994087    18563158    24120638    28004739    21347285    17615350    23691247    24495485    21909270    24905695   

EMBL

AY886742    AB190802    AAW78358.1    BAD51413.1    BABH01036287    BABH01036288    + More
BABH01036289    MG431819    AWX63642.1    KP407133    AKM12418.1    MF370559    RSAL01000160    AWA45967.1    RVE45454.1    KQ460366    KPJ15604.1    NWSH01007921    PCG62751.1    KM215271    AIJ00868.1    EF611125    ABR08302.1    KZ149958    PZC76443.1    AGBW02012439    OWR45060.1    MF991881    AWA45975.1    GAIX01003709    JAA88851.1    GU115810    ACY70995.1    EF114291    ABL63640.1    KK852562    KDR21306.1    KY661320    AVA17407.1    KP099968    AKM12646.1    FX985483    BAX29643.1    DQ205424    ABB05539.1    EU077525    ABU55004.1    KF156268    AGV76057.1    DQ157765    AAZ81617.1    AAZX01008089    NNAY01000061    OXU31412.1    HQ852225    AEK77428.1    KC461130    AGI99530.1    KC333178    AGH30393.1    FM213476    CAR82602.1    GQ478988    ADB90402.1    NEVH01026389    PNF14357.1    FM213470    CAR82596.1    FM213479    CAR82605.1    GDRN01000147    JAI68014.1    JX101466    AFN29184.1    FJ605170    JX133232    ACM61856.2    AFP89582.1    JQ763321    AFK82511.1    AF264029    AAF74770.1    FM213469    CAR82595.1    GBYB01013005    GBYB01013007    JAG82772.1    JAG82774.1    KZ288241    PBC31279.1    FM213474    CAR82600.1    FM213472    CAR82598.1    FM213477    CAR82603.1    FM213475    CAR82601.1    FM213471    CAR82597.1    JN637476    JN662941    AET74062.1    AET74063.1    AY329356    AAP93582.1    FM213481    CAR82607.1    KQ414851    KOC60215.1    FM213473    CAR82599.1    FM213480    CAR82606.1    KQ435012    KZC13862.1    GL435030    EFN74179.1    GL446605    EFN87555.1    GBYB01013004    JAG82771.1    FN652905    CBJ19215.1    AMQN01000856    KB296703    ELU11436.1    FM213478    CAR82604.1    RCHS01002830    RMX45412.1    LC154964    KQ971361    BAV32138.1    EFA09191.1    KK107154    QOIP01000001    EZA56942.1    RLU26398.1    AMQM01007545    KB097640    ESN92464.1    KU057379    AMZ80133.2    HQ115573    KF516615    ADV59552.1    AII16519.1    GL762910    EFZ20441.1    HM563680    ADM64421.1    KK120839    KFM79167.1    LSMT01000323    PFX20288.1    KU323377    AQQ11197.1    AB591738    BAJ21358.1    GEBQ01028667    JAT11310.1    KU323381    AQQ11201.1    KU323379    KU323380    KU323382    AQQ11199.1    AQQ11200.1    AQQ11202.1    CH916375    EDV98383.1    GG666514    EEN60148.1    KQ978317    KYM95219.1    LNIX01000022    OXA43475.1    JX402922    KU323368    KU323369    KU323370    KU323371    KU323372    KU323373    KU323375    KU323376    KU323378    AFS33106.1    AQQ11188.1    AQQ11189.1    AQQ11190.1    AQQ11191.1    AQQ11192.1    AQQ11193.1    AQQ11195.1    AQQ11196.1    AQQ11198.1    LN609528    CEF64881.1    KU323374    AQQ11194.1    AJVK01058555    GEZM01050447    JAV75588.1    GECZ01016439    JAS53330.1    ADTU01027848    DS469511    EDO49016.1    MWRG01000250    PRD36653.1    AK417363    BAN20578.1    GAMC01003352    JAC03204.1    GECU01022975    JAS84731.1    AAGJ04088089    UZAH01026761    VDO85026.1    KX695149    APH81360.1    KF471137    AHE13889.1   

Proteomes

UP000005204    UP000283053    UP000053240    UP000218220    UP000007151    UP000027135    + More
UP000002358    UP000215335    UP000235965    UP000242457    UP000005203    UP000053825    UP000076502    UP000000311    UP000008237    UP000014760    UP000275408    UP000007266    UP000053097    UP000279307    UP000015101    UP000054359    UP000225706    UP000001070    UP000035681    UP000001554    UP000078542    UP000198287    UP000035680    UP000035682    UP000092462    UP000005205    UP000001593    UP000046392    UP000007110    UP000095284    UP000050761   

PRIDE

Q65Y02    H9JD56   

Pfam

PF00081   Sod_Fe_N        + More
PF02777   Sod_Fe_C

Interpro

IPR001189   Mn/Fe_SOD        + More
IPR036324   Mn/Fe_SOD_N_sf       
IPR036314   SOD_C_sf       
IPR019832   Mn/Fe_SOD_C       
IPR019833   Mn/Fe_SOD_BS       
IPR019831   Mn/Fe_SOD_N       

SUPFAM

SSF54719   SSF54719        + More
SSF46609   SSF46609       

Gene 3D

1.10.287.990     2.40.500.20    

ProteinModelPortal

Q65Y02   H9JD56   A0A2Z4N450   A0A0H3WLT1   A0A2S0RQT9   A0A0N0PD16   + More
A0A2A4ISP3   A0A0K0KJP6   A5Z1R7   A0A2W1BXF6   A0A212EU89   A0A2S0RQQ5   S4P9M2   D1M6Z4   A1E9A8   A0A067RBP2   A0A2P0XIZ9   A0A0H3WJR5   A0A3G9D4G0   A2SUH5   A7UL75   T2FE54   Q3Y596   K7IT33   A0A232FL74   G0Z047   M9T285   M4QL80   E6YCY4   D3J1L2   A0A2J7PDG3   E6YCX8   E6YCY7   A0A0P4WJN8   I6VM78   B9VUA3   I3VPK0   Q9NB66   E6YCX7   A0A0C9RVL9   A0A2A3EJB2   E6YCY2   E6YCY0   E6YCY5   E6YCY3   E6YCX9   A0A088A1K0   S4S5N4   Q7YXM5   E6YCY9   A0A0L7QNL3   E6YCY1   E6YCY8   A0A154PPR8   E1ZX89   E2B9W8   A0A0C9R9C6   H1ZSY8   R7V502   E6YCY6   A0A3M6TVI6   D6WWA9   A0A026WLL5   T1G7C2   A0A166AJ53   H2B644   E9IG44   F8R8R3   A0A087UP78   A0A2B4RVE0   A0A2I2MNA6   E1CPV0   A0A1B6KIM9   A0A2I2MNA9   A0A2I2MNB0   B4JWP5   A0A0K0EMH0   C3YI11   A0A195C2Y0   A0A226DD29   A0A0K0F4D5   J9XY23   A0A090L504   A0A2I2MNA3   A0A1B0DF57   A0A1Y1LRX0   A0A1B6FT12   A0A158NW84   A7RHP7   A0A0N5C416   A0A2P6LDK6   R4WD37   W8C1Z3   A0A1B6ICS9   W4Z933   A0A1I7S0V0   A0A183FRG8   A0A3P7YB45   A0A1L3THW9   A0A096X914  

PDB

3DC6     E-value=1.84586e-76,     Score=724

KEGG

692736    K04564 superoxide dismutase, Fe-Mn family [EC:1.15.1.1] | (RefSeq) Sod2; Mn superoxide dismutase

PATHWAY

04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)
04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04146    Peroxisome - Bombyx mori (domestic silkworm)
04213    Longevity regulating pathway - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0004784   GO:0030145   GO:0005739   GO:0006801   GO:0007018   GO:0008017   GO:0019287   GO:0005634   GO:0006334   GO:0003779   GO:0016021   GO:0055114  

Length:

214

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06295

Exp number, first 60 AAs:

0

Total prob of N-in:

0.10627

outside

1  -  214

 

 

Pi

194.417121

Theta

223.126563

Tajima's D

-0.405172

CLR

0.614531

CSRT

0.267936603169842

Interpretation

Uncertain