Gene

KWMTBOMO01166

Pre Gene Modal

BGIBMGA007456

Annotation

PREDICTED:_kinesin-like_protein_unc-104_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr3(-):3718046-3723565      View in EpiBrowser

Full name

Kinesin-like protein unc-104      

Alternative Name

Protein immaculate connections

Location in the cell

Mitochondrial   Reliability : 2.269

CDS

ATGACCCGCTTGGAGCAGGTGGGCCGCACGCGCCACCTCCTCGCACTCCGGGAGAGGCTGCGGCACGGACACGAGAACACGGTCGCGCCCAACGACTTCACCAAGACAGAGAAGGAGGTGTGCAACATGGCGGCGAAGGCGGCGGCCGAGGGCGGGCGCGACGAGCCCGTGTACGAGCCCTGGGACATGTCGCCCAAGGAACGAGAGCTCGCCACCAAATTCATTAAGCTCATGCAAGGAAGAATAGGTTCGACGGGCAAGGAAGTAGAGACCGCAGTGTCTCCCGCCACGCCCGTGGACGAGGGCGTTTCCGCTGACATCTCCACTCCGAGTCTCCTGTCGTCCATACACAGCGCTAGCAGCTTTGAGCTGTGCTCCCCGGAGCGCGCGATGCTGGAGAAGGCGGCGTGCGGGTGGGGGGCGGCGGGCGGCGCGCTGTACGTGCCCGACTGCGAGGAGGTGCGCGTGTCCGCCGCCGTGGCGCGCCGCGGACACCTCAACGTGCTGCAGCACGGCACGCACGGCTGGAAGAAACGCTGGCTGGTGGTCCGGAGGCCGTACGTGTTCATATACCGCGACGAGCGCGACCCCATCGAGCGCGCCGTCATCAACCTCGCCAACGCGCACGTCGAGTACTCCGAGGACCAGGAGCAGATGGTGCGCATGCCCAACACCTTCAGTGTGGTGAGCAAGGAGCGCGGCTACTTACTTCAGACGTTAAGCGACAAGGAGGTGCACGACTGGCTGTACGCGATCAACCCGCTGCTCGCCGGACAGATAAGGTCGCGGTCGGGCCGCCGCGGCGACAAGCCGGCGCCGCTGTCGGCATGA

Protein

MTRLEQVGRTRHLLALRERLRHGHENTVAPNDFTKTEKEVCNMAAKAAAEGGRDEPVYEPWDMSPKERELATKFIKLMQGRIGSTGKEVETAVSPATPVDEGVSADISTPSLLSSIHSASSFELCSPERAMLEKAACGWGAAGGALYVPDCEEVRVSAAVARRGHLNVLQHGTHGWKKRWLVVRRPYVFIYRDERDPIERAVINLANAHVEYSEDQEQMVRMPNTFSVVSKERGYLLQTLSDKEVHDWLYAINPLLAGQIRSRSGRRGDKPAPLSA

Description

Required for presynaptic maturation, has a role in axonal transport of dense-core vesicles carrying synaptic vesicle precursors, components required for the morphological transformation of axonal growth cones to mature boutons.

Subunit

Monomer (By similarity). Interacts with Arl8 (PubMed:30174114).

Similarity

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Unc-104 subfamily.

Keywords

Alternative splicing   ATP-binding   Cell projection   Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Microtubule   Motor protein   Nucleotide-binding   Phosphoprotein   Protein transport   Reference proteome   Transport  

Feature

chain  Kinesin-like protein unc-104
splice variant  In isoform E.

Uniprot

H9JD59   A0A2A4JK74   A0A194QAA2   A0A2H1WUC8   A0A2A4JKZ3   A0A212EU86   + More
A0A2W1BS23   A0A146LD53   A0A0K8T9H4   A0A0A9X329   A0A1B6M3I6   A0A0A9X260   A0A0C9RLS1   A0A0C9R567   K7IT34   A0A1B6GCQ3   A0A2S2NJT1   E1ZX90   A0A1B6JET4   A0A034V9U3   A0A1B6CAU0   A0A232FKZ6   A0A034V5H7   A0A026WLV1   A0A1B6CXY8   A0A1B6EGN6   B4H745   A0A2J7Q5K0   A0A2J7Q5K2   A0A2J7Q5K3   A0A069DYB2   A0A2J7Q5K1   A0A023F4N9   A0A2J7Q5K8   A0A088A1K2   A0A1B6ENW4   A0A0B4KF91   V9I8D8   A0A0Q5VLZ2   A0A0B4K767   A0A2M4B8N3   V9I998   A0A0R1DSQ4   A0A126GUN3   V9I754   A0A0Q5VL17   A0A0R1DY12   V9I8V6   A0A0J9U3U3   A0A0J9REJ2   A0A0J9RE31   A0A195C3P2   A0A0Q5VLV3   A0A0Q5VM46   A0A0Q5VU10   A0A0Q5VY14   A0A0B4K7D4   A1ZAJ2-3   A1ZAJ2   A0A0Q5VLD5   A0A0R1DWB8   A0A0Q5W0T5   A0A182GAH2   B4P5W2   A0A0Q5VLV6   A0A0R1DTA7   A0A0Q5W0R5   A1ZAJ2-2   A0A0R1DY40   B4HT85   A0A0R1DY25   A0A0R1DZ56   A0A0Q5VZM5   A0A0R1DUM0   B4QIF3   A0A0J9RFJ7   A0A0J9RFK3   A0A0J9RED2   A0A0J9RFJ1   A0A0J9REI7   B3NP74   A0A0J9U3T7   A0A0J9U3U8   X1WXH4   A0A0R1DSR7   A0A0R1DSJ0   A0A0R1DSK4   A0A0J9REC5   A0A0J9RE41   A0A1A9UHE4   A0A182P844   A0A2M4AF39   A0A1W4UY03   T1HYD7   A0A1W4UKR8   A0A1W4UXZ7   A0A182MYA1   A0A139WDX9   A0A2S2QWZ1   D6WVN9  

Pubmed

19121390    26354079    22118469    28756777    26823975    25401762    + More
20075255    20798317    25348373    28648823    24508170    17994087    26334808    25474469    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    22936249    17643120    18327897    30174114    26483478    18057021    18362917    19820115   

EMBL

BABH01036281    BABH01036282    NWSH01001135    PCG72457.1    KQ459249    KPJ02359.1    + More
ODYU01011089    SOQ56607.1    PCG72456.1    AGBW02012439    OWR45063.1    KZ149958    PZC76444.1    GDHC01012441    JAQ06188.1    GBRD01003619    JAG62202.1    GBHO01029538    GBHO01029536    JAG14066.1    JAG14068.1    GEBQ01009481    JAT30496.1    GBHO01029540    GBHO01029539    JAG14064.1    JAG14065.1    GBYB01007926    JAG77693.1    GBYB01007927    JAG77694.1    AAZX01006711    AAZX01008089    GECZ01009573    JAS60196.1    GGMR01004810    MBY17429.1    GL435030    EFN74180.1    GECU01010057    JAS97649.1    GAKP01020407    JAC38545.1    GEDC01026764    JAS10534.1    NNAY01000061    OXU31411.1    GAKP01020411    JAC38541.1    KK107154    EZA56943.1    GEDC01019020    JAS18278.1    GEDC01000210    JAS37088.1    CH479216    EDW33578.1    NEVH01017557    PNF23862.1    PNF23863.1    PNF23861.1    GBGD01000122    JAC88767.1    PNF23859.1    GBBI01002340    JAC16372.1    PNF23860.1    GECZ01030174    JAS39595.1    AE013599    AGB93565.1    JR036090    AEY56917.1    CH954179    KQS62419.1    AFH08126.1    GGFJ01000263    MBW49404.1    JR036084    AEY56914.1    CM000158    KRK00166.1    KRK00169.1    ALI30182.1    JR036086    AEY56915.1    KQS62413.1    KRK00162.1    JR036088    AEY56916.1    CM002911    KMY94345.1    KMY94346.1    KMY94338.1    KQ978317    KYM95220.1    KQS62422.1    KQS62417.1    KQS62421.1    KQS62414.1    AFH08127.1    AF247761    AAF74192.1    KQS62416.1    KRK00163.1    KRK00165.1    KQS62415.1    JXUM01050916    KQ561667    KXJ77862.1    EDW91878.1    KRK00164.1    KQS62423.1    KRK00175.1    KRK00178.1    KQS62424.1    KRK00170.1    CH480816    EDW48186.1    KRK00177.1    KRK00167.1    KQS62418.1    KQS62420.1    KRK00171.1    KRK00174.1    CM000362    EDX07400.1    KMY94336.1    KMY94342.1    KMY94343.1    KMY94344.1    KMY94349.1    KMY94347.1    KMY94339.1    KMY94341.1    EDV55713.1    KMY94340.1    KMY94350.1    ABLF02019510    KRK00173.1    KRK00176.1    KRK00168.1    KRK00172.1    KMY94337.1    KMY94348.1    GGFK01006062    MBW39383.1    ACPB03010694    ACPB03010695    ACPB03010696    ACPB03010697    KQ971357    KYB26178.1    GGMS01012980    MBY82183.1    EFA08595.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000002358    UP000000311    + More
UP000215335    UP000053097    UP000008744    UP000235965    UP000005203    UP000000803    UP000008711    UP000002282    UP000078542    UP000069940    UP000249989    UP000001292    UP000000304    UP000007819    UP000078200    UP000075885    UP000192221    UP000015103    UP000075884    UP000007266   

PRIDE

H9JD59    A1ZAJ2   

Pfam

PF00169   PH        + More
PF12423   KIF1B
PF00498   FHA
PF12473   DUF3694
PF16183   Kinesin_assoc
PF00225   Kinesin
PF02731   SKIP_SNW

Interpro

IPR011993   PH-like_dom_sf        + More
IPR001849   PH_domain       
IPR019821   Kinesin_motor_CS       
IPR027417   P-loop_NTPase       
IPR032405   Kinesin_assoc       
IPR036961   Kinesin_motor_dom_sf       
IPR001752   Kinesin_motor_dom       
IPR022140   Kinesin-like_KIF1-typ       
IPR027640   Kinesin-like_fam       
IPR008984   SMAD_FHA_dom_sf       
IPR000253   FHA_dom       
IPR022164   Kinesin-like       
IPR004015   SKI-int_prot_SKIP_SNW-dom       

SUPFAM

SSF49879   SSF49879        + More
SSF52540   SSF52540       

Gene 3D

2.30.29.30     3.40.850.10    

CDD

cd00060  FHA

ProteinModelPortal

H9JD59   A0A2A4JK74   A0A194QAA2   A0A2H1WUC8   A0A2A4JKZ3   A0A212EU86   + More
A0A2W1BS23   A0A146LD53   A0A0K8T9H4   A0A0A9X329   A0A1B6M3I6   A0A0A9X260   A0A0C9RLS1   A0A0C9R567   K7IT34   A0A1B6GCQ3   A0A2S2NJT1   E1ZX90   A0A1B6JET4   A0A034V9U3   A0A1B6CAU0   A0A232FKZ6   A0A034V5H7   A0A026WLV1   A0A1B6CXY8   A0A1B6EGN6   B4H745   A0A2J7Q5K0   A0A2J7Q5K2   A0A2J7Q5K3   A0A069DYB2   A0A2J7Q5K1   A0A023F4N9   A0A2J7Q5K8   A0A088A1K2   A0A1B6ENW4   A0A0B4KF91   V9I8D8   A0A0Q5VLZ2   A0A0B4K767   A0A2M4B8N3   V9I998   A0A0R1DSQ4   A0A126GUN3   V9I754   A0A0Q5VL17   A0A0R1DY12   V9I8V6   A0A0J9U3U3   A0A0J9REJ2   A0A0J9RE31   A0A195C3P2   A0A0Q5VLV3   A0A0Q5VM46   A0A0Q5VU10   A0A0Q5VY14   A0A0B4K7D4   A1ZAJ2-3   A1ZAJ2   A0A0Q5VLD5   A0A0R1DWB8   A0A0Q5W0T5   A0A182GAH2   B4P5W2   A0A0Q5VLV6   A0A0R1DTA7   A0A0Q5W0R5   A1ZAJ2-2   A0A0R1DY40   B4HT85   A0A0R1DY25   A0A0R1DZ56   A0A0Q5VZM5   A0A0R1DUM0   B4QIF3   A0A0J9RFJ7   A0A0J9RFK3   A0A0J9RED2   A0A0J9RFJ1   A0A0J9REI7   B3NP74   A0A0J9U3T7   A0A0J9U3U8   X1WXH4   A0A0R1DSR7   A0A0R1DSJ0   A0A0R1DSK4   A0A0J9REC5   A0A0J9RE41   A0A1A9UHE4   A0A182P844   A0A2M4AF39   A0A1W4UY03   T1HYD7   A0A1W4UKR8   A0A1W4UXZ7   A0A182MYA1   A0A139WDX9   A0A2S2QWZ1   D6WVN9  

PDB

1EAZ     E-value=0.0170618,     Score=88

KEGG

101742157    K10392 kinesin family member 1 | (RefSeq) kinesin-like protein unc-104

GO

GO:0007018   GO:0008017   GO:0005524   GO:0003777   GO:0005681   GO:0000398   GO:0016887   GO:0016192   GO:0051963   GO:0030742   GO:0016188   GO:0045886   GO:0032024   GO:0046847   GO:0040012   GO:0007528   GO:0047496   GO:0015031   GO:0005874   GO:0048814   GO:0048490   GO:0030425   GO:0030424   GO:0008089   GO:0005875   GO:0008088   GO:0007411   GO:0045202   GO:0008345   GO:0048489   GO:1904115   GO:0016021   GO:0005871   GO:0008574   GO:0030705  

PANTHER

PTHR24115  

Subcellular location

Cytoplasm   Microtubule-associated.   With evidence from 5 publications.
Cytoskeleton   Microtubule-associated.   With evidence from 5 publications.
Cell projection   Microtubule-associated.   With evidence from 5 publications.
Axon   Microtubule-associated.   With evidence from 5 publications.

Length:

276

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.000720000000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.08276

outside

1  -  276

 

 

Pi

249.226165

Theta

18.567629

Tajima's D

-1.304764

CLR

0.890088

CSRT

0.0858957052147393

Interpretation

Uncertain