Gene

KWMTBOMO01164

Pre Gene Modal

BGIBMGA010175

Annotation

PREDICTED:_vacuolar_protein_sorting-associated_protein_11_homolog_[Bombyx_mori]

Location

Bomo_Chr3(+):3691786-3705790      View in EpiBrowser

Full name

Vacuolar protein sorting-associated protein 11 homolog      

Location in the cell

Cytoplasmic   Reliability : 2.473

CDS

ATGGCGTTTTTAGAGTGGCGAAGATTTACTTTTTTTGATGTTCAAAACGGTGCTGACAACGGGAAGATCGCAGAGTGCCTTCAAGATACAAATGTAACAGTTGCGACCAGTGGTAATGGTCAAGTTGTACTGTGCGATGACACAGGGTGGGCCCATTTGATTTCTAGGTTGTGGGCGATCACTTCGTTCAAAGCTTATGAAATAACTATAACACAAGCTCAGCAGTTACCACATGATCCTTATCTAGTTACTATAGGGGATGATGAGCCAGGTGTGAATCCCCTTATAAAAGTATGGGACTTGTCTCGCACTGATAGACATGGAAATCCTATATGCGTACGTGTTTCGAGAGCCGTTCCATCACATATGCGACCTATGCATGTCACAGCCCTGGCTGTTCACGAAAACAAAAATCTGCTCGCTGTAGGATTCCAAGATGGTTCAGTAGCCTTATACAGAGGAGACATAGCCAGGCAACGTAGCGGCAAGATGAGGACACTTGCTGAAACCGGCTCCAGCCCCATCACTGGTCTTGCCTTCAAAGGAGCTGAGAAACTGTTCGTGGTGTCTCGCGTGTCTGTGATGCTGGTTTGGCTGAGCACAGACAGATGCGAGTCCCTGGACCCGATGGGGGCGGCGCCCGGATGCAGCGTTTTGGCGGACAAGCATCGACTCACAGTAGCCACTAACAAGGCGATATACTGCTACACAACCGAAGGTAGAGGCCCGTGCTACGCGCTCGAAGGTGACAAAGTCGCGTTGAACTGTTTCCGCAGCTACCTGGTCATCACGGCCAATGAGCCCGCGGCCAAACCCGGGGCGACGACCAGTACGGCCCCGGCCGCGCGCTCGCACCACATCACGATACTCGACATACAGAACAAGTTCATTGTTTTCTCGAAGACGTTCGACGAAATCGACGCGGTCATAACCGAGTGGGGCTCGTTCTATTTGCTCACGAAGAAGAAGGAGCTGATCTATCTGAACGAGAAAGACCTGCAGTCGAAGCTGTCGTCGCTGTTCAAGAAAAATCTCTACGACGTCGCTATAAGGATAGCGAGCAGCCAACATTACGACGTCGAAGGTCTCACCGAGATCTACAAGCAGTACGGGGATCACTTGTACAGCAAGGGCGATTTGAAAGGAGCCATAGATCAATACGTCAAAACTATAGGCTGGTTAGAGACTTCGTACGTCATTCGCAAGTACCTGGAGTCCCGTCACTTGGAGCCTCTGATCATATACCTCGAAGCCCTACATAAGAAGGGCTTCGCCACCGAAGACCACACCACATTACTGCTGACCTGCTACGTGAAGATCGACCAGCACGACCAACAGGGCAAGCTGAAGGAATTTATCAACACTAAAGATAAGACGATAGATTTTGATGTGGATGTGGCTATAAAGGTGGTGCGTCAAGTAAGCGTGGACGACGCTCTGTCGTTAGCGGCCATACACAAGCGCCACGACTGCTACCTTCAAATAGTGATCGAAGACAAGAAGGACTTCAAGCAGGCCCTGGACTACATCGTGGAGCTGGAGTTCGAGGACGCCGACGCGTACATGAAGAAGTACGGGCACAGGCTGATACAGCACGAACCTGAAGATAGCACGAAGCTGCTCAAACTACTGTGCACGGACTACAAGCCCCGCAGCAAGCCGCTGGTGGACGAGACGTCGCTGTCCGGGGGCCACAGGGAGCCGGACCGGGCGGCACCGGACGACTACATACACATGTTCCTGAGCAACTCGGCTAAACTCATAGAGTTTTTGGAGCACATGGTCGCTCATAACCCGGAGTGTTCCAAACTAGTTTACGACGCACTCATCGAGCACTATATACATGTCTGGGTGAAATCGCCTGAGAGCGAGAAGAAGGAATACGAAGAGAAAGTTCTACGAATACTCAGAGATCCCGAGGCCAATTACGATAGAGATCAAACACTGATCATTTGTCAGACCTTGGGCTTCAAACCGGGAGTGCTGTATATGTACGAGGAGAATAAATTATGGCGGTCGCAGGTGTCGCTGTACCTGCGGGAGGGGCAGGCGGAGGCGGCGCTGGCGGTGTGTCGGCGCCGCGCCGCGCTGTGCCCCGCGCTGTGGCTGGACGTGCTGTGGCACCCGCCGCCCGCCGCCTGCCTGCCCGAGCTGCTGCACGTCATAGATACGGAAAAGCTGCTGTCGCGGACTCTGGTCGTGGACTGCTTGGCCAGTCACTCCGCGTACACTCTCGGAGACGTGAGGAAATACCTGATGGACATACTGAAGAACGAGAACGAGGTGATAGCGCGCGAGCAGGAGCTGGCTCGCAAGTACCGGGGCGAGGGCGAGCGCATGAAGGCGCACATCCAGCGGATACAGCGCGAGCCGGTCGTGTTCCAGAGCTCGCGCTGCGCCGCCTGCACCAAGCTGCTGGAGCTGCCCAGCGTGCACTTCCTGTGCCAGCACTCCTTCCACAAGCAGTGA

Protein

MAFLEWRRFTFFDVQNGADNGKIAECLQDTNVTVATSGNGQVVLCDDTGWAHLISRLWAITSFKAYEITITQAQQLPHDPYLVTIGDDEPGVNPLIKVWDLSRTDRHGNPICVRVSRAVPSHMRPMHVTALAVHENKNLLAVGFQDGSVALYRGDIARQRSGKMRTLAETGSSPITGLAFKGAEKLFVVSRVSVMLVWLSTDRCESLDPMGAAPGCSVLADKHRLTVATNKAIYCYTTEGRGPCYALEGDKVALNCFRSYLVITANEPAAKPGATTSTAPAARSHHITILDIQNKFIVFSKTFDEIDAVITEWGSFYLLTKKKELIYLNEKDLQSKLSSLFKKNLYDVAIRIASSQHYDVEGLTEIYKQYGDHLYSKGDLKGAIDQYVKTIGWLETSYVIRKYLESRHLEPLIIYLEALHKKGFATEDHTTLLLTCYVKIDQHDQQGKLKEFINTKDKTIDFDVDVAIKVVRQVSVDDALSLAAIHKRHDCYLQIVIEDKKDFKQALDYIVELEFEDADAYMKKYGHRLIQHEPEDSTKLLKLLCTDYKPRSKPLVDETSLSGGHREPDRAAPDDYIHMFLSNSAKLIEFLEHMVAHNPECSKLVYDALIEHYIHVWVKSPESEKKEYEEKVLRILRDPEANYDRDQTLIICQTLGFKPGVLYMYEENKLWRSQVSLYLREGQAEAALAVCRRRAALCPALWLDVLWHPPPAACLPELLHVIDTEKLLSRTLVVDCLASHSAYTLGDVRKYLMDILKNENEVIAREQELARKYRGEGERMKAHIQRIQREPVVFQSSRCAACTKLLELPSVHFLCQHSFHKQ

Description

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.

Similarity

Belongs to the VPS11 family.

Uniprot

A0A2A4IT99   A0A212EUE1   A0A2H1X1M0   A0A194QA10   A0A0N1I8L3   A0A067RE45   + More
A0A026WHP3   A0A2J7PDD6   A0A088AR40   A0A158NLL7   E1ZWD6   A0A195F4V9   A0A2A3EC13   A0A0C9RN20   A0A0M9A8X3   A0A0L7R8R8   A0A232EGF7   A0A195C3W0   A0A195DB18   A0A151X865   A0A195AY30   E9IQA9   A0A1W4XGV5   A0A139WDA7   A0A0T6B3U8   A0A1B6LZ17   A0A1Y1K3U0   A0A0J7NUV3   F4WXH0   N6U876   A0A2P8YVJ4   U4U3M1   E0VW28   V4BXE9   A0A1S3H9S9   A0A069DXR3   A0A2R7X5T0   A0A1B6CM32   C3YKV1   A0A0P4VT65   A0A023F228   A0A0B7AUN2   A0A1B6FD02   E2B3X3   K1RBA4   T1ISE0   A0A0B7AV21   A0A2J7PDC9   A0A0A9YMZ6   A0A1B0GLW6   R7T5T9   A0A2P6KML9   A0A210QLE0   A0A2G8JUN8   A0A2R5L7R7   A0A224XAR6   A0A1L8DVY0   B0W989   Q17E86   Q17E85   A0A0P5AKZ0   A0A0P5C778   A0A0P4ZEE2   A0A0P5SSW1   A0A0N8EAX1   A0A0P5CXC6   A0A0P5T6Y4   A0A0N8CDB0   A0A0P6GXN0   A0A0N8CU72   A0A0P5U7Q4   A0A164Y4M2   A0A0N8B6K7   A0A0P5WM73   A0A0P5J637   A0A0P5W166   A0A0P5URG0   A0A0P6BVM1   A0A0P5P590   A0A0P5N402   A0A0P5JW52   A0A0P5R8M1   A0A0P6CPC9   E9FYR1   A0A0N8CCV4   A0A0N8CVH7   S4RXC1   A0A0N8C5R1   A0A084W709   A0A0P5KXW3   A0A0P4XS11   A0A182QH22   A0A182Y6R1   A0A182J983   A0A2T7PGB6   A0A182NR94   A0A1W5ACQ6   A0A1B0CT92   A0A182K702  

Pubmed

22118469    26354079    24845553    24508170    21347285    20798317    + More
28648823    21282665    18362917    19820115    28004739    21719571    23537049    29403074    20566863    23254933    26334808    18563158    27129103    25474469    22992520    25401762    26823975    28812685    29023486    17510324    21292972    24438588    25244985   

EMBL

NWSH01007354    PCG62995.1    AGBW02012439    OWR45064.1    ODYU01012745    SOQ59209.1    + More
KQ459249    KPJ02358.1    KQ460366    KPJ15598.1    KK852562    KDR21303.1    KK107218    EZA55171.1    NEVH01026389    PNF14338.1    ADTU01002180    ADTU01002181    GL434809    EFN74505.1    KQ981805    KYN35620.1    KZ288289    PBC29268.1    GBYB01009735    JAG79502.1    KQ435711    KOX79645.1    KQ414631    KOC67277.1    NNAY01004774    OXU17433.1    KQ978344    KYM94863.1    KQ981042    KYN10110.1    KQ982431    KYQ56510.1    KQ976716    KYM76849.1    GL764688    EFZ17252.1    KQ971361    KYB25939.1    LJIG01015993    KRT81937.1    GEBQ01011049    JAT28928.1    GEZM01096588    JAV54780.1    LBMM01001510    KMQ96170.1    GL888424    EGI61136.1    APGK01035610    APGK01035611    KB740928    ENN77870.1    PYGN01000337    PSN48268.1    KB632064    ERL88484.1    DS235816    EEB17584.1    KB201890    ESO93774.1    GBGD01000273    JAC88616.1    KK857417    PTY27148.1    GEDC01022845    JAS14453.1    GG666523    EEN59169.1    GDKW01000799    JAI55796.1    GBBI01003728    JAC14984.1    HACG01036861    CEK83726.1    GECZ01021673    JAS48096.1    GL445407    EFN89642.1    JH817349    EKC43018.1    JH431430    HACG01036860    CEK83725.1    PNF14339.1    GBHO01020690    GBHO01011131    GBRD01006587    GDHC01010548    JAG22914.1    JAG32473.1    JAG59234.1    JAQ08081.1    AJVK01009151    AJVK01009152    AJVK01009153    AMQN01003443    KB311801    ELT88573.1    MWRG01008660    PRD27534.1    NEDP02003085    OWF49568.1    MRZV01001241    PIK39430.1    GGLE01001418    MBY05544.1    GFTR01008402    JAW08024.1    GFDF01003494    JAV10590.1    DS231862    EDS39786.1    CH477284    EAT44793.1    EAT44792.1    GDIP01200778    JAJ22624.1    GDIP01179365    JAJ44037.1    GDIP01227159    JAI96242.1    GDIP01135773    JAL67941.1    GDIQ01044701    GDIQ01044700    JAN50037.1    GDIP01164116    JAJ59286.1    GDIP01134525    JAL69189.1    GDIP01142967    JAL60747.1    GDIQ01039752    JAN54985.1    GDIP01098471    JAM05244.1    GDIP01120677    JAL83037.1    LRGB01000930    KZS14879.1    GDIQ01207803    JAK43922.1    GDIP01085181    JAM18534.1    GDIQ01206448    JAK45277.1    GDIP01093426    JAM10289.1    GDIP01109480    JAL94234.1    GDIP01024402    JAM79313.1    GDIQ01154448    JAK97277.1    GDIQ01151557    JAL00169.1    GDIQ01192594    JAK59131.1    GDIQ01106228    JAL45498.1    GDIQ01089775    JAN04962.1    GL732527    EFX87578.1    GDIQ01092227    JAL59499.1    GDIP01094831    JAM08884.1    GDIQ01112171    JAL39555.1    ATLV01021084    KE525312    KFB46003.1    GDIQ01177692    JAK74033.1    GDIP01238516    JAI84885.1    AXCN02001467    PZQS01000004    PVD32476.1    AJWK01027296   

Proteomes

UP000218220    UP000007151    UP000053268    UP000053240    UP000027135    UP000053097    + More
UP000235965    UP000005203    UP000005205    UP000000311    UP000078541    UP000242457    UP000053105    UP000053825    UP000215335    UP000078542    UP000078492    UP000075809    UP000078540    UP000192223    UP000007266    UP000036403    UP000007755    UP000019118    UP000245037    UP000030742    UP000009046    UP000030746    UP000085678    UP000001554    UP000008237    UP000005408    UP000092462    UP000014760    UP000242188    UP000230750    UP000002320    UP000008820    UP000076858    UP000000305    UP000245300    UP000030765    UP000075886    UP000076408    UP000075880    UP000245119    UP000075884    UP000192224    UP000092461    UP000075881   

Pfam

PF00637   Clathrin        + More
PF12451   VPS11_C

Interpro

IPR001841   Znf_RING        + More
IPR036322   WD40_repeat_dom_sf       
IPR000547   Clathrin_H-chain/VPS_repeat       
IPR013083   Znf_RING/FYVE/PHD       
IPR016528   VPS11       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR001680   WD40_repeat       
IPR024763   VPS11_C       
IPR016024   ARM-type_fold       

SUPFAM

SSF50978   SSF50978        + More
SSF48371   SSF48371       

Gene 3D

1.25.40.10     2.130.10.10     3.30.40.10    

ProteinModelPortal

A0A2A4IT99   A0A212EUE1   A0A2H1X1M0   A0A194QA10   A0A0N1I8L3   A0A067RE45   + More
A0A026WHP3   A0A2J7PDD6   A0A088AR40   A0A158NLL7   E1ZWD6   A0A195F4V9   A0A2A3EC13   A0A0C9RN20   A0A0M9A8X3   A0A0L7R8R8   A0A232EGF7   A0A195C3W0   A0A195DB18   A0A151X865   A0A195AY30   E9IQA9   A0A1W4XGV5   A0A139WDA7   A0A0T6B3U8   A0A1B6LZ17   A0A1Y1K3U0   A0A0J7NUV3   F4WXH0   N6U876   A0A2P8YVJ4   U4U3M1   E0VW28   V4BXE9   A0A1S3H9S9   A0A069DXR3   A0A2R7X5T0   A0A1B6CM32   C3YKV1   A0A0P4VT65   A0A023F228   A0A0B7AUN2   A0A1B6FD02   E2B3X3   K1RBA4   T1ISE0   A0A0B7AV21   A0A2J7PDC9   A0A0A9YMZ6   A0A1B0GLW6   R7T5T9   A0A2P6KML9   A0A210QLE0   A0A2G8JUN8   A0A2R5L7R7   A0A224XAR6   A0A1L8DVY0   B0W989   Q17E86   Q17E85   A0A0P5AKZ0   A0A0P5C778   A0A0P4ZEE2   A0A0P5SSW1   A0A0N8EAX1   A0A0P5CXC6   A0A0P5T6Y4   A0A0N8CDB0   A0A0P6GXN0   A0A0N8CU72   A0A0P5U7Q4   A0A164Y4M2   A0A0N8B6K7   A0A0P5WM73   A0A0P5J637   A0A0P5W166   A0A0P5URG0   A0A0P6BVM1   A0A0P5P590   A0A0P5N402   A0A0P5JW52   A0A0P5R8M1   A0A0P6CPC9   E9FYR1   A0A0N8CCV4   A0A0N8CVH7   S4RXC1   A0A0N8C5R1   A0A084W709   A0A0P5KXW3   A0A0P4XS11   A0A182QH22   A0A182Y6R1   A0A182J983   A0A2T7PGB6   A0A182NR94   A0A1W5ACQ6   A0A1B0CT92   A0A182K702  

KEGG

101739023    K20179 vacuolar protein sorting-associated protein 11 | (RefSeq) vacuolar protein sorting-associated

GO

GO:0006886   GO:0016192   GO:0005623   GO:0007032   GO:0006904   GO:0030674   GO:0016020   GO:0035542   GO:0030897   GO:0007033   GO:0005768   GO:0016021   GO:0031902   GO:1902362   GO:0005765   GO:0033263   GO:0006914   GO:0030318   GO:0003406   GO:0005769   GO:0001889   GO:0030136   GO:0010507   GO:0005776   GO:0003407   GO:0048794   GO:0060036   GO:0005515   GO:0004163   GO:0005829   GO:0019287   GO:0005634   GO:0006334   GO:0003779  

PANTHER

PTHR23323:SF24  

Subcellular location

Late endosome membrane  
Lysosome membrane  
Cytoplasmic vesicle  
Early endosome  
Autophagosome  
Clathrin-coated vesicle  

Length:

822

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00327000000000001

Exp number, first 60 AAs:

0.00057

Total prob of N-in:

0.00014

outside

1  -  822

 

 

Pi

354.4232

Theta

185.229314

Tajima's D

2.734313

CLR

0.176677

CSRT

0.963101844907755

Interpretation

Uncertain