Gene

KWMTBOMO01147  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007460

Annotation

PREDICTED:_serine/threonine-protein_phosphatase_2A_catalytic_subunit_beta_isoform_isoform_X1_[Papilio_polytes]

Location

Bomo_Chr3(-):3333031-3352751      View in EpiBrowser

Full name

Serine/threonine-protein phosphatase      

Location in the cell

Cytoplasmic   Reliability : 4.246

CDS

ATGGAGGACAAGGCGTCGCTTAAAGAACTAGATCAATGGATACAACAGCTAAATGAATGCAAGCAATTGACAGAAAATCAAGTTAAAACGTTATGTGACAAGGCAAAGGAGATCCTGACGAAGGAATCTAACGTCCAAGAAGTAAAATGTCCGGTGACCGTATGCGGCGACGTGCACGGTCAGTTTCACGACTTGATGGAGCTGTTCCGCATCGGGGGACGTTCTCCGGATACCAACTACCTGTTCATGGGCGACTACGTGGACCGCGGCTACTACAGTGTCGAAACGGTCACATTGCTCGTTGCGCTTAAGGTGCGTTACCGCGAGAGAATAACCATTCTGCGAGGAAATCACGAATCGCGTCAGATTACTCAAGTGTACGGCTTCTACGACGAGTGTCTCCGGAAATACGGCAACGCGTCCGTCTGGAAGCACTTCACCGATCTATTCGATTTCCTGCCCTTGACGGCGCTCGTAGATGGACAGATATTCTGCCTGCACGGTGGACTCAGTCCGTCAATCGACACCCTCGACCACATCAGAGCTCTGGACCGTCTGCAGGAAGTGCCCCACGAAGGACCCATGTGCGATCTCCTCTGGAGTGATCCCGATGACAGAGGTGGATGGGGCATATCTCCCCGTGGAGCCGGCTACACGTTCGGACAGGACATCTCGGAGACGTTCAACCACAGCAACGGGCTCACGCTCGTGTCCCGCGCCCACCAGCTCGTCATGGAGGGGTACAACTGGTGCCACGACAGAAACGTCGTCACTATATTCTCAGCGCCCAACTACTGCTATAGATGTGGTAATCAAGCCGCCATAATGGAATTGGATGATGCACTCAAGTATTCATTCCTGCAGTTCGACCCCGCCCCGCGCCGCGGCGAGCCGCACGTCACGCGGCGGACGCCAGATTACTTCATGTAG

Protein

MEDKASLKELDQWIQQLNECKQLTENQVKTLCDKAKEILTKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGRSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNASVWKHFTDLFDFLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHSNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDALKYSFLQFDPAPRRGEPHVTRRTPDYFM

Catalytic Activity

H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate

Similarity

Belongs to the PPP phosphatase family.

Uniprot

A0A2W1BEB7   H9JD63   A0A0N1IF94   J9Z496   S4NTW7   R4JXR1   + More
A0A0J7KTX9   A0A212F8S6   W0FWA3   E9IAY8   A0A2J7QGM9   A0A067R4M1   A0A1B6J5X6   A0A1B6MAE1   A0A151IL48   E0VKT2   A0A224XSY9   A0A2R7WXL3   A0A1W4WWX6   A0A0P4VHB8   A0A0V0G7R6   A0A023FBB7   A0A1B6GNJ1   A0A0C9RWT2   A0A2P8XHX5   A0A3L8DHC5   A0A069DSI5   R4G8Q4   A0A0A9XQC5   A0A293MR39   A0A2R5LJB9   A0A131Y1R5   B7QGY5   A0A232F1C1   A0A023GL94   A0A1E1XAZ0   A0A1Y1MPP5   D6WUS6   A0A2A3EAK5   V9IGX0   A0A088A299   A0A310SEU0   A0A224YZ24   A0A131YKP7   L7M975   A0A131XGZ3   A0A0P7W006   A0A1L8DX29   N6TIR0   A0A1Q3EU52   A0A151I4P7   A0A1B6D177   A0A1B6DHP0   Q6P365   A0A023EP91   T1DEL2   U5EZ91   A0A2M4A3D0   A0A2M4BUS2   W5JPS4   Q16K96   A0A084VQ06   A0A182J3G6   T1IWX4   H3BA28   A0A154PMP8   A0A1L8GR14   W5MVW9   T1DHS1   A0A2M3Z181   A0A182Q164   A0A1W4ZHJ9   K4G048   A0A3N0XWC3   A0A0E9XQ14   A0A3B4E0S8   Q803G3   A0A0P7Y7K0   A0A1Q3EU39   A0A0K8TSF2   F1Q6Z7   A0A2J8X5K2   Q58D70   A0A182KJN6   A0A151XDL3   A0A182V317   A0A182JWB8   A0A182WA72   A0A182XB18   Q7PD38   A0A182R7S1   A0A182I0L4   A0A250XY70   G3WVY5   W5MXU4   A0A3B1IJE7   A0A3B4D6N4   Q8AVH9   Q1ZZQ4   A0A3B3RMU3  

EC Number

3.1.3.16

Pubmed

28756777    19121390    26354079    23622113    22118469    21282665    + More
24845553    20566863    27129103    25474469    29403074    30249741    26334808    25401762    26823975    28648823    28503490    28004739    18362917    19820115    28797301    26830274    25576852    28049606    23537049    20431018    24945155    24330624    20920257    23761445    17510324    24438588    9215903    27762356    23056606    25613341    23594743    26369729    11282978    16305752    20966253    12364791    14747013    17210077    28087693    21709235    25329095    1662645    29240929   

EMBL

KZ150100    PZC73519.1    BABH01036247    BABH01036248    BABH01036249    KQ460366    + More
KPJ15580.1    JX398253    KC429039    AFS50168.1    AGI37441.1    GAIX01012056    JAA80504.1    KC558556    AGK93074.1    LBMM01003233    KMQ93778.1    AGBW02009673    OWR50155.1    KF255599    AHF45926.1    GL762091    EFZ22272.1    NEVH01014361    PNF27746.1    KK852699    KDR18186.1    GECU01013127    JAS94579.1    GEBQ01010587    GEBQ01007153    JAT29390.1    JAT32824.1    KQ977133    KYN05485.1    DS235250    EEB13988.1    GFTR01004866    JAW11560.1    KK855891    PTY24279.1    GDKW01002769    JAI53826.1    GECL01002717    JAP03407.1    GBBI01000494    JAC18218.1    GECZ01005775    JAS63994.1    GBYB01012296    JAG82063.1    PYGN01002070    PSN31599.1    QOIP01000008    RLU19844.1    GBGD01002252    JAC86637.1    ACPB03007814    GAHY01000567    JAA76943.1    GBHO01021768    GBRD01010201    GDHC01017013    GDHC01003020    JAG21836.1    JAG55623.1    JAQ01616.1    JAQ15609.1    GFWV01018606    MAA43334.1    GGLE01005514    MBY09640.1    GEFM01003820    JAP71976.1    ABJB010027498    ABJB011093211    ABJB011107534    DS935429    EEC18107.1    NNAY01001328    OXU24343.1    GBBM01001833    JAC33585.1    GFAC01002783    JAT96405.1    GEZM01024972    JAV87663.1    KQ971363    EFA07805.1    KZ288311    PBC28504.1    JR047185    AEY60348.1    KQ761976    OAD56418.1    GFPF01011691    MAA22837.1    GEDV01009419    JAP79138.1    GACK01004607    JAA60427.1    GEFH01002282    JAP66299.1    JARO02000151    KPP79672.1    GFDF01003118    JAV10966.1    APGK01036313    APGK01036314    KB740939    KB631813    ENN77718.1    ERL86376.1    GFDL01016214    JAV18831.1    KQ976460    KYM84751.1    GEDC01017963    GEDC01005069    GEDC01001282    JAS19335.1    JAS32229.1    JAS36016.1    GEDC01028231    GEDC01016801    GEDC01012095    JAS09067.1    JAS20497.1    JAS25203.1    AAMC01051493    BC064168    CR761518    AAH64168.1    CAJ82598.1    GAPW01002797    JAC10801.1    GALA01000987    JAA93865.1    GANO01001215    JAB58656.1    GGFK01001909    MBW35230.1    GGFJ01007685    MBW56826.1    ADMH02000460    ETN66387.1    CH477971    EAT34719.1    ATLV01015102    KE525002    KFB40050.1    AXCP01005389    JH431634    AFYH01018774    AFYH01018775    AFYH01018776    KQ434972    KZC12734.1    CM004471    OCT86303.1    AHAT01021380    GAMD01002196    JAA99394.1    GGFM01001505    MBW22256.1    AXCN02001856    JX052413    AFK10641.1    RJVU01059915    ROJ62421.1    GBXM01004804    JAI03774.1    BX537303    BC044495    BC065680    AAH44495.1    AAH65680.1    JARO02009432    KPP61644.1    GFDL01016216    JAV18829.1    GDAI01000309    JAI17294.1    FP017197    NDHI03003372    PNJ77310.1    BT021727    AAX46574.1    KQ982268    KYQ58462.1    AAAB01008980    EAA13875.4    APCN01005219    GFFV01003631    JAV36314.1    AEFK01014627    AEFK01014628    AEFK01014629    AEFK01014630    AEFK01014631    AEFK01014632    AEFK01014633    AHAT01013380    AHAT01013381    BC042272    AAH42272.1    ABLF02035577    ABLF02035580    DQ416022    AK342594    ABD76369.1    BAH72564.1   

Proteomes

UP000005204    UP000053240    UP000036403    UP000007151    UP000235965    UP000027135    + More
UP000078542    UP000009046    UP000192223    UP000245037    UP000279307    UP000015103    UP000001555    UP000215335    UP000007266    UP000242457    UP000005203    UP000034805    UP000192224    UP000019118    UP000030742    UP000078540    UP000008143    UP000000673    UP000008820    UP000030765    UP000075880    UP000008672    UP000076502    UP000186698    UP000018468    UP000075886    UP000261440    UP000000437    UP000075882    UP000075809    UP000075903    UP000075881    UP000075920    UP000076407    UP000007062    UP000075900    UP000075840    UP000007648    UP000018467    UP000007819    UP000261540   

PRIDE

H9JD63    E9IAY8    E0VKT2    B7QGY5    D6WUS6    A0A088A299    + More
Q58D70    Q8AVH9    Q1ZZQ4   

Pfam

PF00149   Metallophos

Interpro

IPR029052   Metallo-depent_PP-like        + More
IPR006186   Ser/Thr-sp_prot-phosphatase       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR001611   Leu-rich_rpt       
IPR032675   LRR_dom_sf       

Gene 3D

3.60.21.10     3.80.10.10    

ProteinModelPortal

A0A2W1BEB7   H9JD63   A0A0N1IF94   J9Z496   S4NTW7   R4JXR1   + More
A0A0J7KTX9   A0A212F8S6   W0FWA3   E9IAY8   A0A2J7QGM9   A0A067R4M1   A0A1B6J5X6   A0A1B6MAE1   A0A151IL48   E0VKT2   A0A224XSY9   A0A2R7WXL3   A0A1W4WWX6   A0A0P4VHB8   A0A0V0G7R6   A0A023FBB7   A0A1B6GNJ1   A0A0C9RWT2   A0A2P8XHX5   A0A3L8DHC5   A0A069DSI5   R4G8Q4   A0A0A9XQC5   A0A293MR39   A0A2R5LJB9   A0A131Y1R5   B7QGY5   A0A232F1C1   A0A023GL94   A0A1E1XAZ0   A0A1Y1MPP5   D6WUS6   A0A2A3EAK5   V9IGX0   A0A088A299   A0A310SEU0   A0A224YZ24   A0A131YKP7   L7M975   A0A131XGZ3   A0A0P7W006   A0A1L8DX29   N6TIR0   A0A1Q3EU52   A0A151I4P7   A0A1B6D177   A0A1B6DHP0   Q6P365   A0A023EP91   T1DEL2   U5EZ91   A0A2M4A3D0   A0A2M4BUS2   W5JPS4   Q16K96   A0A084VQ06   A0A182J3G6   T1IWX4   H3BA28   A0A154PMP8   A0A1L8GR14   W5MVW9   T1DHS1   A0A2M3Z181   A0A182Q164   A0A1W4ZHJ9   K4G048   A0A3N0XWC3   A0A0E9XQ14   A0A3B4E0S8   Q803G3   A0A0P7Y7K0   A0A1Q3EU39   A0A0K8TSF2   F1Q6Z7   A0A2J8X5K2   Q58D70   A0A182KJN6   A0A151XDL3   A0A182V317   A0A182JWB8   A0A182WA72   A0A182XB18   Q7PD38   A0A182R7S1   A0A182I0L4   A0A250XY70   G3WVY5   W5MXU4   A0A3B1IJE7   A0A3B4D6N4   Q8AVH9   Q1ZZQ4   A0A3B3RMU3  

PDB

5W0W     E-value=0,     Score=1652

KEGG

101737820    K04382 serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] | (RefSeq) serine/thr

PATHWAY

03015    mRNA surveillance pathway - Bombyx mori (domestic silkworm)
04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)
04136    Autophagy - other - Bombyx mori (domestic silkworm)
04140    Autophagy - animal - Bombyx mori (domestic silkworm)
04350    TGF-beta signaling pathway - Bombyx mori (domestic silkworm)
04391    Hippo signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0004721   GO:0016787   GO:0046982   GO:0004722   GO:0005829   GO:0035970   GO:0000775   GO:0010719   GO:0045121   GO:0071902   GO:0007498   GO:0005886   GO:0000159   GO:0045202   GO:0008022   GO:0050811   GO:0016021   GO:0016020   GO:0022891   GO:0022857   GO:0045905   GO:0005634   GO:0006334   GO:0003779  

Length:

309

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04318

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02489

outside

1  -  309

 

 

Pi

190.102568

Theta

18.883685

Tajima's D

0.070887

CLR

1.395646

CSRT

0.395530223488826

Interpretation

Uncertain