Silkworm Genome Informatics Database

Gene

KWMTBOMO01127

Pre Gene Modal

BGIBMGA007442

Annotation

atypical_protein_kinase_C_[Bombyx_mori]

Location

Bomo_Chr3(-):2853895-2857166 View in EpiBrowser

Location in the cell

Cytoplasmic Reliability : 1.705 Nuclear Reliability : 1.457

CDS

ATGCCGACACAACTTGTGAATCAGGATAACCATGTAAATGATGTACGAGTGAAAACTGTCTACAATGGAGATGTGATGATCACATACATCAACCATAACATAACCTTTGAGGAGTTTACACATGAGATGGTGGCTACTTGCCGTTTTGCTCCAGATCAGGTGTTTACAATGAAATGGGTGGATGAAGAAGGTGATCCCTGCACAATATCAACACAGCTAGAGCTGGATGAGTCACTGAGGCTGTACGAGTTGAACCGAGACTCCGAACTCACTGTACATGGTATGTTAATACTTTCAACTAATACAATAGAAAAATTAGATTGGGGACCAATTCTCCAAAACATTTTTTATGGGGTTATGGAAGACCCTATTAGTCAAGCCCAGAAAATAGTTCCAGGCACTCGAGTACAGTCTGAGAGGCTGTATTATCAGCTTCCATGA

Protein

MPTQLVNQDNHVNDVRVKTVYNGDVMITYINHNITFEEFTHEMVATCRFAPDQVFTMKWVDEEGDPCTISTQLELDESLRLYELNRDSELTVHGMLILSTNTIEKLDWGPILQNIFYGVMEDPISQAQKIVPGTRVQSERLYYQLP

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Similarity

Belongs to the protein kinase superfamily.

Uniprot

H9JD45 A0A182R164 A0A182W253 A0A182RMQ3 U5Q3S1 A0A182XFQ2 + More
Q7PZN0 A0A182HHS0 A0A182U312 A0A182MH99 A0A182KLL7 B4HRS6 A0A1A9Y730 A0A1B0C6M9

Pubmed

19121390 24146884 12364791 20966253 17994087

EMBL

BABH01041496 AXCN02001803 KC896833 AGY49604.1 AAAB01008986 EAA00497.3 + More
APCN01002437 AXCM01001642 AXCM01001643 CH480816 EDW47940.1 JXJN01026831

Proteomes

UP000005204 UP000075886 UP000075920 UP000075900 UP000076407 UP000007062 + More
UP000075840 UP000075902 UP000075883 UP000075882 UP000001292 UP000092443 UP000092460

PRIDE

H9JD45

Pfam

PF00564   PB1        + More
PF00433   Pkinase_C
PF00069   Pkinase
PF00130   C1_1

Interpro

IPR034877   PB1_aPKC        + More
IPR000270   PB1_dom
IPR011009   Kinase-like_dom_sf
IPR017892   Pkinase_C
IPR000719   Prot_kinase_dom
IPR000961   AGC-kinase_C
IPR002219   PE/DAG-bd
IPR017441   Protein_kinase_ATP_BS
IPR008271   Ser/Thr_kinase_AS

SUPFAM

SSF56112 SSF56112

CDD

cd06404 PB1_aPKC
cd00029 C1

ProteinModelPortal

H9JD45 A0A182R164 A0A182W253 A0A182RMQ3 U5Q3S1 A0A182XFQ2 + More
Q7PZN0 A0A182HHS0 A0A182U312 A0A182MH99 A0A182KLL7 B4HRS6 A0A1A9Y730 A0A1B0C6M9

PDB

1WMH E-value=3.60442e-24, Score=270

KEGG

692468 K06069 atypical protein kinase C iota type [EC:2.7.11.13] | (RefSeq) Apkc; atypical protein kinase C

PATHWAY

04144 Endocytosis - Bombyx mori (domestic silkworm)
04391 Hippo signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0035556 GO:0046872 GO:0004697 GO:0005524 GO:0005515 GO:0015074 GO:0006468 GO:0004674 GO:0005634 GO:0008270 GO:0006334 GO:0003779 GO:0016021

Length:

146

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01169

Exp number, first 60 AAs:

0.00934

Total prob of N-in:

0.21948

outside

1 - 146

Pi

176.977693

Theta

189.948322

Tajima's D

-0.269146

CLR

0.920385

CSRT

0.296135193240338

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics