SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO01123  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA007441
Annotation
PREDICTED:_inositol-3-phosphate_synthase_[Amyelois_transitella]
Full name
Inositol-3-phosphate synthase      
Alternative Name
Myo-inositol 1-phosphate synthase
Location in the cell
Cytoplasmic   Reliability : 1.907
 

Sequence

CDS
ATGGAAAAAACACCAAATTTGGTTATAGTCAGTCCGAATGTGAAATATTCGGATGATTTTATTTACGCCGATTACGAGTATAACGAAACATTAGTGAAAAAAATCGACAATCAGTTAGTGGCACAGCCGTACAGCAAAACTTTGAGCATTAGGACTCAGCGTAAAGTTGGCAAAGTTGGAGTGATGCTAGTGGGATGGGGTGGCAACAATGGTTCAACATTTACTGCGGCTGTTTTGGCCAACCGACACCAGTTGTCCTGGAACACAAAGAATGGCTCTCTAGATGCTAATTGGTTTGGTTCGATCACACAAGCATCGACTGTGAGACTGGGGTTAGATGAAAAAGGGAATGATGTGAATGTGCCAATGAACAGTTTACTGCCGATGGTGAACCCTGATGATCTATTTATTGATGGCTGGGACATAAGTCCTCTCAATTTGGCGGAGTCGATGGCTCGAGCTAAGGTCCTCGATTATGATCTGCAGCAGAAACTGAAAAAGGAGATGGCCACTATGAAACCGAGACCAGCTATTTATGATCCTGACTTCATTGCTGCGAATCAGGCCGATCGTGCTACGAACCTCATCCACGGCACGAAGTACGAGCAGTACCTGCAAATCCGCGCCGATATCAAGGACTTCAAGGATAAGAACAAACTGGACAAAGTCATAGTTGTCTGGACGGCGAACACTGAAAGGTTCTGCGAGGTCCGCGACGGCGTGCACGACACGAGCGACAACTTGGAGAAGGCGCTGCGGGACAACGAGCCGGAGATATCGCCGTCCACCATCATCGCGCTCGCTTCGATCGACGAGGGGTGTTGCTATATCAACGGCGCGCCTCAAAACACTTTGATCCCGGGCGTCATAGAGCGGGCCGAGAAACGAGGGGTCTTCGTGGCTGGCGACGACTTCAAATCAGGACAGACCAAGCTTAAGTCAGTACTCGTCGACTTCTTGGTTTCGGCTGGTCTGAAACCGGTGTCGATAGTGAGCTACAACCATCTCGGCAACAACGACGGTAAGAATCTCTCCGCTCCGAAGCAGTTCCGCTCGAAAGAGATCAGCAAGAGCAGCGTGGTGGACGACGCGGTGCAGTCGAACGGCGTGCTGTACCGGCCCGGGGAGCGCCCCGACCACGTGGTCGTCATCAAGTACGTGCCCTACGTCGGTGACTCGAAGCGCGCCATGGACGAGTACACGTCGGAGATCCTGCTGCACGGCACGAACACGCTGGTGGTGCACAACACGTGCGAGGACTCGCTGCTGGCGGCGCCGCTGCTGCTGGACCTGGCGGTGCTGGCGGAGCTGCTGGGGCGCGTGGCGCTGCGGGCGGGCGGCGCGTGGGCGGCGCTGCACCCCGCGCTGTCGCCGCTCGCCTACCTGCTGAAGGCGCCGCTGGTGCCGGCGGGCGCGCCCGTCGTCAACGCGCTGTCCAAGCAGCGCGCCTGCATCGACAACCTGCTGCGCGCCTGCCTCGGCCTGCCCTGTCTACACAACATGCAGCTCGAGCATAAGGTACCGTTTCTAATGAGCGAGCTCCGTGACGGGTCGATGTTCGCCGGCGCCCCTGCGTTTAAGAAGCCCAAATTGGATCAAGAAAATGGCGATCAATAA
Protein
MEKTPNLVIVSPNVKYSDDFIYADYEYNETLVKKIDNQLVAQPYSKTLSIRTQRKVGKVGVMLVGWGGNNGSTFTAAVLANRHQLSWNTKNGSLDANWFGSITQASTVRLGLDEKGNDVNVPMNSLLPMVNPDDLFIDGWDISPLNLAESMARAKVLDYDLQQKLKKEMATMKPRPAIYDPDFIAANQADRATNLIHGTKYEQYLQIRADIKDFKDKNKLDKVIVVWTANTERFCEVRDGVHDTSDNLEKALRDNEPEISPSTIIALASIDEGCCYINGAPQNTLIPGVIERAEKRGVFVAGDDFKSGQTKLKSVLVDFLVSAGLKPVSIVSYNHLGNNDGKNLSAPKQFRSKEISKSSVVDDAVQSNGVLYRPGERPDHVVVIKYVPYVGDSKRAMDEYTSEILLHGTNTLVVHNTCEDSLLAAPLLLDLAVLAELLGRVALRAGGAWAALHPALSPLAYLLKAPLVPAGAPVVNALSKQRACIDNLLRACLGLPCLHNMQLEHKVPFLMSELRDGSMFAGAPAFKKPKLDQENGDQ

Summary

Catalytic Activity
D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate
Cofactor
NAD(+)
Similarity
Belongs to the myo-inositol 1-phosphate synthase family.
Keywords
Complete proteome   Cytoplasm   Inositol biosynthesis   Isomerase   Lipid biosynthesis   Lipid metabolism   NAD   Phospholipid biosynthesis   Phospholipid metabolism   Phosphoprotein   Reference proteome  
Feature
chain  Inositol-3-phosphate synthase
EC Number
5.5.1.4
EMBL
BABH01027813    BABH01027814    BABH01027815    BABH01027816    BABH01027817    KQ459249    + More
KPJ02325.1    KQ460685    KPJ12797.1    NWSH01000370    PCG76910.1    GAMC01015618    GAMC01015617    JAB90937.1    NEVH01002987    PNF41107.1    GAKP01002615    JAC56337.1    GDHF01014841    JAI37473.1    KQ971357    EFA09280.1    CCAG010005392    AJWK01016483    AJWK01016484    KK852699    KDR18213.1    CH916367    EDW00949.1    JXUM01081571    JXUM01081572    JXUM01081573    KQ563255    KXJ74195.1    CH933808    EDW09982.1    GFDF01002428    JAV11656.1    CH477254    EAT45917.1    EAT45918.1    JXUM01091697    JXUM01091698    JXUM01091699    KQ563935    KXJ73050.1    JRES01001254    KNC24206.1    CP012524    ALC40855.1    KA647170    KA649733    KA649753    AFP64362.1    CH963849    EDW74603.1    AJVK01009514    AJVK01009515    AJVK01009516    OUUW01000001    SPP75670.1    CM000071    EAL25351.1    CH479181    EDW32299.1    GALX01005629    JAB62837.1    GEZM01016729    JAV91162.1    AXCN02001095    CH902619    EDV36441.1    CM000157    EDW89182.1    CVRI01000040    CRK95020.1    CH954177    EDV59687.1    UFQT01000092    SSX19588.1    AXCM01000489    AMQN01008410    KB303059    ELU03519.1    AAAB01008986    EAA00329.3    CM002911    KMY91977.1    AF071103    AF071104    AE013599    AY122137    BT001560    BT001772    GFDL01005494    JAV29551.1    JR037601    AEY57868.1    KB200665    ESP00812.1    DS231941    EDS28093.1    GFDL01005495    JAV29550.1    ATLV01023946    KE525347    KFB50135.1    ADMH02000915    ETN64673.1    CH940648    EDW60990.1    GGLE01004683    MBY08809.1    KE163515    EPQ12449.1    GEBQ01000716    JAT39261.1    KK116827    KFM68884.1    JP011804    AES00402.1    KZ288478    PBC25266.1    KQ434870    KZC09470.1    GANO01002053    JAB57818.1    ADTU01003756    AEYP01051416    KQ414681    KOC63962.1    GL888331    EGI62697.1    GL436621    EFN71722.1    KQ981768    KYN36022.1    AAPE02040677    KQ976701    KYM77211.1    KQ435955    KOX68055.1    KB030270    ELK19191.1    RCHS01002306    RMX48175.1    GL451555    EFN79046.1    AANG04000016    GDIP01044160    JAM59555.1    GECU01011475    JAS96231.1   
Pfam
PF01658   Inos-1-P_synth        + More
PF07994   NAD_binding_5
PF04410   Gar1
PF07225   NDUF_B4
Interpro
IPR013021   Myo-inos-1-P_Synthase_GAPDH        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR002587   Myo-inos-1-P_Synthase       
IPR038664   Gar1/Naf1_Cbf5-bd_sf       
IPR007504   H/ACA_rnp_Gar1/Naf1       
IPR009000   Transl_B-barrel_sf       
IPR009866   NADH_UbQ_OxRdtase_NDUFB4_su       
SUPFAM
SSF51735   SSF51735        + More
SSF50447   SSF50447       
Gene 3D
PDB
1RM0     E-value=3.82012e-141,     Score=1287

Ontologies

Topology

Subcellular location
Cytoplasm  
Length:
538
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
1.22721
Exp number, first 60 AAs:
0.13722
Total prob of N-in:
0.05201
outside
1  -  538
 
 

Population Genetic Test Statistics

Pi
181.952662
Theta
163.23499
Tajima's D
1.196152
CLR
0.179569
CSRT
0.710964451777411
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
26822097 IIPAIPFQE 100.00 1e-04
25044914 PAEQTPITAIYIAQIVK 100.00 1e-04
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