Gene

KWMTBOMO01123  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007441

Annotation

PREDICTED:_inositol-3-phosphate_synthase_[Amyelois_transitella]

Location

Bomo_Chr3(+):2632042-2650210      View in EpiBrowser

Full name

Inositol-3-phosphate synthase      

Alternative Name

Myo-inositol 1-phosphate synthase

Location in the cell

Cytoplasmic   Reliability : 1.907

CDS

ATGGAAAAAACACCAAATTTGGTTATAGTCAGTCCGAATGTGAAATATTCGGATGATTTTATTTACGCCGATTACGAGTATAACGAAACATTAGTGAAAAAAATCGACAATCAGTTAGTGGCACAGCCGTACAGCAAAACTTTGAGCATTAGGACTCAGCGTAAAGTTGGCAAAGTTGGAGTGATGCTAGTGGGATGGGGTGGCAACAATGGTTCAACATTTACTGCGGCTGTTTTGGCCAACCGACACCAGTTGTCCTGGAACACAAAGAATGGCTCTCTAGATGCTAATTGGTTTGGTTCGATCACACAAGCATCGACTGTGAGACTGGGGTTAGATGAAAAAGGGAATGATGTGAATGTGCCAATGAACAGTTTACTGCCGATGGTGAACCCTGATGATCTATTTATTGATGGCTGGGACATAAGTCCTCTCAATTTGGCGGAGTCGATGGCTCGAGCTAAGGTCCTCGATTATGATCTGCAGCAGAAACTGAAAAAGGAGATGGCCACTATGAAACCGAGACCAGCTATTTATGATCCTGACTTCATTGCTGCGAATCAGGCCGATCGTGCTACGAACCTCATCCACGGCACGAAGTACGAGCAGTACCTGCAAATCCGCGCCGATATCAAGGACTTCAAGGATAAGAACAAACTGGACAAAGTCATAGTTGTCTGGACGGCGAACACTGAAAGGTTCTGCGAGGTCCGCGACGGCGTGCACGACACGAGCGACAACTTGGAGAAGGCGCTGCGGGACAACGAGCCGGAGATATCGCCGTCCACCATCATCGCGCTCGCTTCGATCGACGAGGGGTGTTGCTATATCAACGGCGCGCCTCAAAACACTTTGATCCCGGGCGTCATAGAGCGGGCCGAGAAACGAGGGGTCTTCGTGGCTGGCGACGACTTCAAATCAGGACAGACCAAGCTTAAGTCAGTACTCGTCGACTTCTTGGTTTCGGCTGGTCTGAAACCGGTGTCGATAGTGAGCTACAACCATCTCGGCAACAACGACGGTAAGAATCTCTCCGCTCCGAAGCAGTTCCGCTCGAAAGAGATCAGCAAGAGCAGCGTGGTGGACGACGCGGTGCAGTCGAACGGCGTGCTGTACCGGCCCGGGGAGCGCCCCGACCACGTGGTCGTCATCAAGTACGTGCCCTACGTCGGTGACTCGAAGCGCGCCATGGACGAGTACACGTCGGAGATCCTGCTGCACGGCACGAACACGCTGGTGGTGCACAACACGTGCGAGGACTCGCTGCTGGCGGCGCCGCTGCTGCTGGACCTGGCGGTGCTGGCGGAGCTGCTGGGGCGCGTGGCGCTGCGGGCGGGCGGCGCGTGGGCGGCGCTGCACCCCGCGCTGTCGCCGCTCGCCTACCTGCTGAAGGCGCCGCTGGTGCCGGCGGGCGCGCCCGTCGTCAACGCGCTGTCCAAGCAGCGCGCCTGCATCGACAACCTGCTGCGCGCCTGCCTCGGCCTGCCCTGTCTACACAACATGCAGCTCGAGCATAAGGTACCGTTTCTAATGAGCGAGCTCCGTGACGGGTCGATGTTCGCCGGCGCCCCTGCGTTTAAGAAGCCCAAATTGGATCAAGAAAATGGCGATCAATAA

Protein

MEKTPNLVIVSPNVKYSDDFIYADYEYNETLVKKIDNQLVAQPYSKTLSIRTQRKVGKVGVMLVGWGGNNGSTFTAAVLANRHQLSWNTKNGSLDANWFGSITQASTVRLGLDEKGNDVNVPMNSLLPMVNPDDLFIDGWDISPLNLAESMARAKVLDYDLQQKLKKEMATMKPRPAIYDPDFIAANQADRATNLIHGTKYEQYLQIRADIKDFKDKNKLDKVIVVWTANTERFCEVRDGVHDTSDNLEKALRDNEPEISPSTIIALASIDEGCCYINGAPQNTLIPGVIERAEKRGVFVAGDDFKSGQTKLKSVLVDFLVSAGLKPVSIVSYNHLGNNDGKNLSAPKQFRSKEISKSSVVDDAVQSNGVLYRPGERPDHVVVIKYVPYVGDSKRAMDEYTSEILLHGTNTLVVHNTCEDSLLAAPLLLDLAVLAELLGRVALRAGGAWAALHPALSPLAYLLKAPLVPAGAPVVNALSKQRACIDNLLRACLGLPCLHNMQLEHKVPFLMSELRDGSMFAGAPAFKKPKLDQENGDQ

Catalytic Activity

D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate

Cofactor

NAD(+)

Similarity

Belongs to the myo-inositol 1-phosphate synthase family.

Keywords

Complete proteome   Cytoplasm   Inositol biosynthesis   Isomerase   Lipid biosynthesis   Lipid metabolism   NAD   Phospholipid biosynthesis   Phospholipid metabolism   Phosphoprotein   Reference proteome  

Feature

chain  Inositol-3-phosphate synthase

Uniprot

H9JD44   A0A194QBG0   A0A194R539   A0A2A4JZS2   W8AXX6   A0A2J7RJU5   + More
A0A1A9WR46   A0A1W4X2G4   A0A034WPS6   A0A0K8VF34   D6WV33   A0A1A9XFG4   A0A1I8PC50   A0A1B0G1H8   A0A1B0CKN3   A0A1A9V3A3   A0A1B0AGG2   A0A067R717   B4J6P6   A0A182GQX6   B4KNC9   A0A1L8DYZ6   Q17H06   A0A182GVS5   A0A0L0BW05   A0A0M4EIF0   T1PP12   B4MR64   A0A1I8NDV0   A0A1B0CZ62   A0A3B0JJW5   A0A182JXK2   Q290L0   B4GBP1   A0A182N3W5   A0A182FUZ8   V5GMK8   A0A1Y1MZR4   A0A182QAP8   B3MDQ6   A0A182HHE3   B4P1P6   A0A182YLA1   A0A182VF33   A0A1J1I609   A0A182XGS6   A0A1S4EBW8   B3N9Z1   A0A336M0U0   A0A1W4V0U6   A0A182MDN0   A0A182RYY1   R7UC15   Q7PZB9   A0A0J9R749   A0A088AHY9   A0A182L4Y4   O97477   A0A1Q3FPL3   V9I9S1   A0A182UEU2   V4B2T7   A0A1S3H4Z5   A0A182P7I1   A0A182W1X7   B0WI11   A0A1Q3FPM1   A0A084WIU1   W5JMX9   B4LMP9   A0A2R5LH56   S7N5Q4   A0A1B6MTK9   A0A087TUU5   A0A182J2U9   A0A1S3IQ99   G9K677   A0A2A3E1Y2   A0A154PE42   U5EV30   A0A158NYD0   M3YVS2   A0A0L7QZJ6   F4WSZ3   E2A4B2   A0A3P9KY71   A0A1X7V072   H2MGD4   A0A195F761   G1NX43   A0A195AYD6   A0A0M8ZNV0   A0A3P9HWT8   L5L7E3   A0A3M6U3B9   E2BZ44   A0A2Y9IYD6   M3WC06   A0A0P6ADI8   A0A1B6JAG6  

EC Number

5.5.1.4

Pubmed

19121390    26354079    24495485    25348373    18362917    19820115    + More
24845553    17994087    26483478    17510324    26108605    25315136    15632085    28004739    17550304    25244985    23254933    12364791    22936249    20966253    11121586    10731132    12537572    12537569    17372656    24438588    20920257    23761445    23236062    21347285    21719571    20798317    17554307    21993624    23258410    30382153    17975172   

EMBL

BABH01027813    BABH01027814    BABH01027815    BABH01027816    BABH01027817    KQ459249    + More
KPJ02325.1    KQ460685    KPJ12797.1    NWSH01000370    PCG76910.1    GAMC01015618    GAMC01015617    JAB90937.1    NEVH01002987    PNF41107.1    GAKP01002615    JAC56337.1    GDHF01014841    JAI37473.1    KQ971357    EFA09280.1    CCAG010005392    AJWK01016483    AJWK01016484    KK852699    KDR18213.1    CH916367    EDW00949.1    JXUM01081571    JXUM01081572    JXUM01081573    KQ563255    KXJ74195.1    CH933808    EDW09982.1    GFDF01002428    JAV11656.1    CH477254    EAT45917.1    EAT45918.1    JXUM01091697    JXUM01091698    JXUM01091699    KQ563935    KXJ73050.1    JRES01001254    KNC24206.1    CP012524    ALC40855.1    KA647170    KA649733    KA649753    AFP64362.1    CH963849    EDW74603.1    AJVK01009514    AJVK01009515    AJVK01009516    OUUW01000001    SPP75670.1    CM000071    EAL25351.1    CH479181    EDW32299.1    GALX01005629    JAB62837.1    GEZM01016729    JAV91162.1    AXCN02001095    CH902619    EDV36441.1    CM000157    EDW89182.1    CVRI01000040    CRK95020.1    CH954177    EDV59687.1    UFQT01000092    SSX19588.1    AXCM01000489    AMQN01008410    KB303059    ELU03519.1    AAAB01008986    EAA00329.3    CM002911    KMY91977.1    AF071103    AF071104    AE013599    AY122137    BT001560    BT001772    GFDL01005494    JAV29551.1    JR037601    AEY57868.1    KB200665    ESP00812.1    DS231941    EDS28093.1    GFDL01005495    JAV29550.1    ATLV01023946    KE525347    KFB50135.1    ADMH02000915    ETN64673.1    CH940648    EDW60990.1    GGLE01004683    MBY08809.1    KE163515    EPQ12449.1    GEBQ01000716    JAT39261.1    KK116827    KFM68884.1    JP011804    AES00402.1    KZ288478    PBC25266.1    KQ434870    KZC09470.1    GANO01002053    JAB57818.1    ADTU01003756    AEYP01051416    KQ414681    KOC63962.1    GL888331    EGI62697.1    GL436621    EFN71722.1    KQ981768    KYN36022.1    AAPE02040677    KQ976701    KYM77211.1    KQ435955    KOX68055.1    KB030270    ELK19191.1    RCHS01002306    RMX48175.1    GL451555    EFN79046.1    AANG04000016    GDIP01044160    JAM59555.1    GECU01011475    JAS96231.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000235965    UP000091820    + More
UP000192223    UP000007266    UP000092443    UP000095300    UP000092444    UP000092461    UP000078200    UP000092445    UP000027135    UP000001070    UP000069940    UP000249989    UP000009192    UP000008820    UP000037069    UP000092553    UP000007798    UP000095301    UP000092462    UP000268350    UP000075881    UP000001819    UP000008744    UP000075884    UP000069272    UP000075886    UP000007801    UP000002282    UP000076408    UP000075903    UP000183832    UP000076407    UP000079169    UP000008711    UP000192221    UP000075883    UP000075900    UP000014760    UP000007062    UP000005203    UP000075882    UP000000803    UP000075902    UP000030746    UP000085678    UP000075885    UP000075920    UP000002320    UP000030765    UP000000673    UP000008792    UP000054359    UP000075880    UP000242457    UP000076502    UP000005205    UP000000715    UP000053825    UP000007755    UP000000311    UP000265180    UP000007879    UP000001038    UP000078541    UP000001074    UP000078540    UP000053105    UP000265200    UP000010552    UP000275408    UP000008237    UP000248482    UP000011712   

PRIDE

H9JD44    O97477   

Pfam

PF01658   Inos-1-P_synth        + More
PF07994   NAD_binding_5
PF04410   Gar1
PF07225   NDUF_B4

Interpro

IPR013021   Myo-inos-1-P_Synthase_GAPDH        + More
IPR036291   NAD(P)-bd_dom_sf       
IPR002587   Myo-inos-1-P_Synthase       
IPR038664   Gar1/Naf1_Cbf5-bd_sf       
IPR007504   H/ACA_rnp_Gar1/Naf1       
IPR009000   Transl_B-barrel_sf       
IPR009866   NADH_UbQ_OxRdtase_NDUFB4_su       

SUPFAM

SSF51735   SSF51735        + More
SSF50447   SSF50447       

Gene 3D

2.40.10.230    

ProteinModelPortal

H9JD44   A0A194QBG0   A0A194R539   A0A2A4JZS2   W8AXX6   A0A2J7RJU5   + More
A0A1A9WR46   A0A1W4X2G4   A0A034WPS6   A0A0K8VF34   D6WV33   A0A1A9XFG4   A0A1I8PC50   A0A1B0G1H8   A0A1B0CKN3   A0A1A9V3A3   A0A1B0AGG2   A0A067R717   B4J6P6   A0A182GQX6   B4KNC9   A0A1L8DYZ6   Q17H06   A0A182GVS5   A0A0L0BW05   A0A0M4EIF0   T1PP12   B4MR64   A0A1I8NDV0   A0A1B0CZ62   A0A3B0JJW5   A0A182JXK2   Q290L0   B4GBP1   A0A182N3W5   A0A182FUZ8   V5GMK8   A0A1Y1MZR4   A0A182QAP8   B3MDQ6   A0A182HHE3   B4P1P6   A0A182YLA1   A0A182VF33   A0A1J1I609   A0A182XGS6   A0A1S4EBW8   B3N9Z1   A0A336M0U0   A0A1W4V0U6   A0A182MDN0   A0A182RYY1   R7UC15   Q7PZB9   A0A0J9R749   A0A088AHY9   A0A182L4Y4   O97477   A0A1Q3FPL3   V9I9S1   A0A182UEU2   V4B2T7   A0A1S3H4Z5   A0A182P7I1   A0A182W1X7   B0WI11   A0A1Q3FPM1   A0A084WIU1   W5JMX9   B4LMP9   A0A2R5LH56   S7N5Q4   A0A1B6MTK9   A0A087TUU5   A0A182J2U9   A0A1S3IQ99   G9K677   A0A2A3E1Y2   A0A154PE42   U5EV30   A0A158NYD0   M3YVS2   A0A0L7QZJ6   F4WSZ3   E2A4B2   A0A3P9KY71   A0A1X7V072   H2MGD4   A0A195F761   G1NX43   A0A195AYD6   A0A0M8ZNV0   A0A3P9HWT8   L5L7E3   A0A3M6U3B9   E2BZ44   A0A2Y9IYD6   M3WC06   A0A0P6ADI8   A0A1B6JAG6  

PDB

1RM0     E-value=3.82012e-141,     Score=1287

KEGG

101745369    K01858 myo-inositol-1-phosphate synthase [EC:5.5.1.4] | (RefSeq) inositol-3-phosphate synthase

PATHWAY

00562    Inositol phosphate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0008654   GO:0004512   GO:0006021   GO:0005737   GO:0001522   GO:0042254   GO:0005739   GO:0008137   GO:0003677   GO:0005634   GO:0008270   GO:0006334   GO:0003779   GO:0016021  

PANTHER

PTHR11510  

Subcellular location

Cytoplasm  

Length:

538

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.22721

Exp number, first 60 AAs:

0.13722

Total prob of N-in:

0.05201

outside

1  -  538

 

 

Pi

181.952662

Theta

163.23499

Tajima's D

1.196152

CLR

0.179569

CSRT

0.710964451777411

Interpretation

Uncertain