Gene

KWMTBOMO01116

Pre Gene Modal

BGIBMGA007331

Annotation

PREDICTED:_protein_MCM10_homolog_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr3(-):2515943-2518231      View in EpiBrowser

Full name

Protein MCM10 homolog      

Alternative Name

Sensitized chromosome inheritance modifier 19

Location in the cell

Nuclear   Reliability : 4.496

CDS

ATGGACGAGAAAGATGAATTATCACAGCTTGAAGAACTGCTCAGTGCTGACTTCGGTGAAAATACTGAAATGAATGCACAAAATAACACCAAAGAAGTAGACATATTTCAGCAAACTACAAACTTAAGAAGTGAAATGCCATCATCAAGTACAGCTGAAGTTCCTTCTATTGTACACAATGGAGATACTGATTCTTCAGACGACGAGGAAAAGCGGGACTATGCAGAAAGGAAGTACAATGATTACGGTTCACAAGTAAAAAAATCATTAGACAAAATTGAACAAGATCAAATTAATCAAAGACTGGATTTTGAGAGTAGATTACGACAAACAAACATGGAAACTAAAGTTTCACGTTATTCCAAATTCACAAAAAAACCTAACATTGAACCTAGAAATGTGTTCAGTCCTCCTAAAGTGAAAAGTAATAAAAATGCAGATGTTTACACAGACCCTATATTCAATATTAGGATTACAAAGCCATTGCTATCTAGTTCAGTTTTGCTAGAGAGAATGCAAGGTAGAGAAGCTATAAGCATGCTTAGAGTAAAAAGGCATGTTGAGAATGAAGACTTGTCAAAAGATTGGGTGATTGCAGGTGTTATTGTTAGGAAAAGTTCAACTAAACAATCTCAGAAAGGAAGTCAGTTTATTATATGGACTCTCAGTGATTTAAAAGATGATATGAAAACGGTTTCTATATTTTTATTTAGGAAAGCCTATAATGAACTATGGAAAACTGCTGAAGGAACAGTTGTTGCAGTTCTTAACCCTAATGTATTAGATAGATCACAGAATAGCGCAGATCAGGCTTGCCTCAGTGTTGATAATCCTGACAGAGTTATGATCATAGGACTCTCCAAAGATTTTGGTATTTGTAAAAGTAAGAAGAAAAATGGGGAACCATGCACAGCCTTTGTCAATATGAATCAATGTCAACACTGCATTTATCATGTAAAACAAGAATACCAAAAGTTTTCACAGAGACAAGAACTACAATCTTCAACCATGGGCAAGGGTTTAGTAAGTTTACAAAATAAAGTTTTAGGAAAAAACACTGTGATCTATGGAGGCAAAGCATATTCAGCCTTACAAAGCGGAAATAACAAAAAGATAAAAGAAAAAGATCAAAACAGACTGATGTCACTCAGTGACTATTACAAAACTGAGGGTGACAAGTTAATCACTAACAAAATGCCTTATGGGGCAGGATTTGTGAAGAACAATAGTGCATTACACAGTCCGACTACACAAAAAACTAGTGATACTGAAAGACTCAGCAAATTGTCCAACTTTAATACACCTACAAACTCAAAACAACTTAGCCTTGCAGAAAAACTGACTAATTCTCCCACATTAGGCAAAGGATTTAGTATAAAAGGCAGTGGAACAATAGACCTAAATATATCATACAAACAAAAGGTAGCTGAAAAAGCAAAATCCAATGCAATCAGAATAATTCAACAGAATGGTGGATTACCAAAATTAGATCCTAATAATTTAAATGGAACTGCTGCTGGGAAAAAAAGAGCTTTAGAAAAATTGAATGGAATGAATGATGAGAATAGCAGTAAAAAAGCAAAATCCAATCATGAACAGAGCAACACTGGGAAAATACTCTCTGAAAGGTTCCGTAAAATATTAGAAGCCACATCAGTACATCAAGACTTAGTAAAACAACATGAAGATGATGAACAAGAGAAGTATTTTAACAAATTAGAGAAAAAGGAAGCAATGGAAGAAAAAATGTTGAGCACATATAAACTTCCATGCAAAGCAGTAAGATGTGCTAAATGTAAATACACTGCATTTTCTGCTGCTCAACGGTGTAAAGATGAAAGACATCCTCTAAAAGTATTAGATACATTTAAGAGGTTCTTTAAATGTTTGGATTGTAAAAATAGAACTGTTTCTTTAGAATTGCTGCCTCTGCATTCTTGTAATAATTGTGGAAGTTCACGGTGGGAGAAAGCTCCAATGTTAAGAGAAAAGAAAATAACGACACTTTCTGATGGTTTATCCATCAGGGGTGAAGAAGAAACATTTTTGGGTGGACAAGTTGCTACTGGCAAAAATATAAATCTATTGGTACCAGACAGCTAA

Protein

MDEKDELSQLEELLSADFGENTEMNAQNNTKEVDIFQQTTNLRSEMPSSSTAEVPSIVHNGDTDSSDDEEKRDYAERKYNDYGSQVKKSLDKIEQDQINQRLDFESRLRQTNMETKVSRYSKFTKKPNIEPRNVFSPPKVKSNKNADVYTDPIFNIRITKPLLSSSVLLERMQGREAISMLRVKRHVENEDLSKDWVIAGVIVRKSSTKQSQKGSQFIIWTLSDLKDDMKTVSIFLFRKAYNELWKTAEGTVVAVLNPNVLDRSQNSADQACLSVDNPDRVMIIGLSKDFGICKSKKKNGEPCTAFVNMNQCQHCIYHVKQEYQKFSQRQELQSSTMGKGLVSLQNKVLGKNTVIYGGKAYSALQSGNNKKIKEKDQNRLMSLSDYYKTEGDKLITNKMPYGAGFVKNNSALHSPTTQKTSDTERLSKLSNFNTPTNSKQLSLAEKLTNSPTLGKGFSIKGSGTIDLNISYKQKVAEKAKSNAIRIIQQNGGLPKLDPNNLNGTAAGKKRALEKLNGMNDENSSKKAKSNHEQSNTGKILSERFRKILEATSVHQDLVKQHEDDEQEKYFNKLEKKEAMEEKMLSTYKLPCKAVRCAKCKYTAFSAAQRCKDERHPLKVLDTFKRFFKCLDCKNRTVSLELLPLHSCNNCGSSRWEKAPMLREKKITTLSDGLSIRGEEETFLGGQVATGKNINLLVPDS

Description

Proposed to be involved in DNA replication and to participate in the activation of the pre-replication complex (pre-RC). May be involved in chromosome condensation.

Subunit

Self-associates. Interacts with Mcm2, dup, Orc2, CDC45L and Su(var)205.

Similarity

Belongs to the MCM10 family.

Keywords

Complete proteome   DNA replication   Metal-binding   Nucleus   Phosphoprotein   Reference proteome   Zinc   Zinc-finger  

Feature

chain  Protein MCM10 homolog

Uniprot

A0A0L7KYK6   A0A2H1W6P2   A0A2W1B2R1   A0A0N1PGC4   A0A194QBH0   A0A2A4JZU4   + More
A0A212F5Y5   A0A336M324   A0A1Q3EWW6   B0W0E0   A0A182GCN5   B0XLH7   Q17D82   A0A1S4F772   A0A336MX92   B4N7B8   A0A1W4UXI8   B3MN70   A0A1I8PQP2   A0A182JWH1   B4GJJ9   Q29NT4   B4IFM1   A0A3B0JMS4   A9UNF9   Q9VIE6   B4JAE6   A0A1I8M363   A0A182NAN1   A0A1Y1K9Q4   B4Q403   B4LU06   B4KF43   A0A1A9UPS9   A0A067RAI8   A0A182R410   A0A084VMI5   A0A0L0CB14   A0A1B0A5T7   A0A1A9Y0C4   B4P6Y2   A0A182JEC0   B3NKT1   A0A182P6F7   A0A1B0FPB2   A0A1B0CH79   A0A3L8DIM1   A0A1B0AS88   A0A0M3QU63   A0A182X691   A0A182IBB1   A0A195FTB8   A0A182KWG2   A0A182VFJ8   A0A182U1B4   A0A151WX28   A0A195DKJ0   F4WBG6   A0A1W4XAW2   A0A158P125   A0A195B3F0   A0A182F3R8   E2BQS1   E2A5U9   A0A0J7KJK8   A0A2R7VPG1   A0A182Q2M5   A0A1J1ING7   A0A026X0J5   A0A0L7QNG6   A0A1W4XAM4   A0A154PQ73   A0A087ZZG6   A0A232EU18   A0A0M9A4X7   A0A2A3EMU5   K7IXJ7   A0A0C9RRY7   A0A336N3B0   A0A310SJL9   T1I9G7   W8BT57   A0A0A1XHM1   A0A0C9RUP4   A0A0K8U4Y0   A0A034VS51   A0A2S2QIN5   E0VMQ2   J9K4B0   E9G6I1   A0A0P4YY76   A0A0P5VC16   A0A0P5ZUC8  

Pubmed

26227816    28756777    26354079    22118469    26483478    17510324    + More
17994087    15632085    23185243    10731132    12537572    12537569    12808023    18327897    25315136    28004739    22936249    24845553    24438588    26108605    17550304    30249741    20966253    21719571    21347285    20798317    24508170    28648823    20075255    24495485    25830018    25348373    20566863    21292972   

EMBL

JTDY01004465    KOB68124.1    ODYU01006615    SOQ48616.1    KZ150559    PZC70538.1    + More
KQ460468    KPJ14589.1    KQ459249    KPJ02335.1    NWSH01000370    PCG76922.1    AGBW02010127    OWR49119.1    UFQT01000336    SSX23329.1    GFDL01015236    JAV19809.1    DS231817    EDS39679.1    JXUM01160059    KQ573563    KXJ67921.1    DS234473    EDS34138.1    CH477298    EAT44347.1    UFQS01003243    UFQT01003243    SSX15421.1    SSX34790.1    CH964182    EDW80259.1    CH902620    EDV31027.1    CH479184    EDW36815.1    CH379058    EAL34560.1    KRT03652.1    CH480833    EDW46443.1    OUUW01000006    SPP82163.1    BT031323    ABY21736.1    AE014134    AY061477    CH916368    EDW03817.1    GEZM01095141    JAV55487.1    CM000361    CM002910    EDX05719.1    KMY91300.1    CH940649    EDW65059.1    CH933807    EDW13026.1    KK852819    KDR15628.1    ATLV01014596    KE524975    KFB39179.1    JRES01000668    KNC29410.1    CM000158    EDW89951.1    CH954179    EDV54454.1    CCAG010016105    AJWK01012087    QOIP01000008    RLU19688.1    JXJN01002691    CP012523    ALC40113.1    APCN01000664    KQ981272    KYN43855.1    KQ982691    KYQ52215.1    KQ980765    KYN13366.1    GL888063    EGI68445.1    ADTU01006100    KQ976641    KYM78807.1    GL449799    EFN81946.1    GL437061    EFN71191.1    LBMM01006623    KMQ90452.1    KK854016    PTY09412.1    AXCN02000614    CVRI01000054    CRL00638.1    KK107064    EZA60919.1    KQ414855    KOC60109.1    KQ435034    KZC14053.1    NNAY01002185    OXU21855.1    KQ435732    KOX77320.1    KZ288212    PBC32814.1    AAZX01004642    GBYB01011340    JAG81107.1    UFQS01003905    UFQT01003905    SSX16024.1    SSX35357.1    KQ761906    OAD56463.1    ACPB03017551    GAMC01014173    GAMC01014171    JAB92384.1    GBXI01003835    JAD10457.1    GBYB01011341    JAG81108.1    GDHF01030914    JAI21400.1    GAKP01014564    JAC44388.1    GGMS01008385    MBY77588.1    AAZO01003684    DS235321    EEB14658.1    ABLF02025674    GL732533    EFX84989.1    GDIP01221876    JAJ01526.1    GDIP01102388    JAM01327.1    GDIP01038996    LRGB01002384    JAM64719.1    KZS07922.1   

Proteomes

UP000037510    UP000053240    UP000053268    UP000218220    UP000007151    UP000002320    + More
UP000069940    UP000249989    UP000008820    UP000007798    UP000192221    UP000007801    UP000095300    UP000075881    UP000008744    UP000001819    UP000001292    UP000268350    UP000000803    UP000001070    UP000095301    UP000075884    UP000000304    UP000008792    UP000009192    UP000078200    UP000027135    UP000075900    UP000030765    UP000037069    UP000092445    UP000092443    UP000002282    UP000075880    UP000008711    UP000075885    UP000092444    UP000092461    UP000279307    UP000092460    UP000092553    UP000076407    UP000075840    UP000078541    UP000075882    UP000075903    UP000075902    UP000075809    UP000078492    UP000007755    UP000192223    UP000005205    UP000078540    UP000069272    UP000008237    UP000000311    UP000036403    UP000075886    UP000183832    UP000053097    UP000053825    UP000076502    UP000005203    UP000215335    UP000053105    UP000242457    UP000002358    UP000015103    UP000009046    UP000007819    UP000000305    UP000076858   

PRIDE

A9UNF9    Q9VIE6   

Pfam

PF09329   zf-primase        + More
PF09332   Mcm10

Interpro

IPR040184   Mcm10        + More
IPR015411   Rep_factor_Mcm10_C       
IPR015408   Znf_Mcm10/DnaG       

ProteinModelPortal

A0A0L7KYK6   A0A2H1W6P2   A0A2W1B2R1   A0A0N1PGC4   A0A194QBH0   A0A2A4JZU4   + More
A0A212F5Y5   A0A336M324   A0A1Q3EWW6   B0W0E0   A0A182GCN5   B0XLH7   Q17D82   A0A1S4F772   A0A336MX92   B4N7B8   A0A1W4UXI8   B3MN70   A0A1I8PQP2   A0A182JWH1   B4GJJ9   Q29NT4   B4IFM1   A0A3B0JMS4   A9UNF9   Q9VIE6   B4JAE6   A0A1I8M363   A0A182NAN1   A0A1Y1K9Q4   B4Q403   B4LU06   B4KF43   A0A1A9UPS9   A0A067RAI8   A0A182R410   A0A084VMI5   A0A0L0CB14   A0A1B0A5T7   A0A1A9Y0C4   B4P6Y2   A0A182JEC0   B3NKT1   A0A182P6F7   A0A1B0FPB2   A0A1B0CH79   A0A3L8DIM1   A0A1B0AS88   A0A0M3QU63   A0A182X691   A0A182IBB1   A0A195FTB8   A0A182KWG2   A0A182VFJ8   A0A182U1B4   A0A151WX28   A0A195DKJ0   F4WBG6   A0A1W4XAW2   A0A158P125   A0A195B3F0   A0A182F3R8   E2BQS1   E2A5U9   A0A0J7KJK8   A0A2R7VPG1   A0A182Q2M5   A0A1J1ING7   A0A026X0J5   A0A0L7QNG6   A0A1W4XAM4   A0A154PQ73   A0A087ZZG6   A0A232EU18   A0A0M9A4X7   A0A2A3EMU5   K7IXJ7   A0A0C9RRY7   A0A336N3B0   A0A310SJL9   T1I9G7   W8BT57   A0A0A1XHM1   A0A0C9RUP4   A0A0K8U4Y0   A0A034VS51   A0A2S2QIN5   E0VMQ2   J9K4B0   E9G6I1   A0A0P4YY76   A0A0P5VC16   A0A0P5ZUC8  

PDB

3EBE     E-value=9.49538e-38,     Score=396

KEGG

101744695    K10736 minichromosome maintenance protein 10 | (RefSeq) protein MCM10 homolog

GO

GO:0006270   GO:0003697   GO:0005634   GO:0003690   GO:0042023   GO:0035214   GO:0070868   GO:1901693   GO:0045931   GO:0045678   GO:0030261   GO:0016321   GO:0046872   GO:0006260   GO:0031298   GO:0003688   GO:0006177   GO:0016462   GO:0006164   GO:0003677   GO:0006334   GO:0003779   GO:0016021  

PANTHER

PTHR13454  

Subcellular location

Nucleus  

Length:

700

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00018

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00011

outside

1  -  700

 

 

Pi

167.90158

Theta

163.329778

Tajima's D

-0.154978

CLR

51.038418

CSRT

0.330633468326584

Interpretation

Uncertain