Gene

KWMTBOMO01064  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007410

Annotation

RNA-binding_protein_lark_[Bombyx_mori]

Location

Bomo_Chr3(+):1480506-1482440      View in EpiBrowser

Full name

RNA-binding protein lark      

Location in the cell

Cytoplasmic   Reliability : 1.46 Nuclear   Reliability : 1.794

CDS

ATGCCGGGCACCGGTACTTTCAAAATCTTCATCGGGAACCTTTCTGATAAAACCACAGAAGCCGATCTTAGACCGCTATTCGAAAAATACGGTACGGTCGTAGAATGCGATATCGTCAGAAATTACGGTTTCGTGCACATGGAAAACGAACAAGTCGGCCGCGAAGCCATTCAGAATCTTAACGGCGAGTTAGTTCATGGGCAGGCGATCAAAATAGAAGCGGCCAAGAGCCGGAAGGCGCCGTCGACGCCAACCACTAAAATATTCGTGGGTAATTTAACGGACAAGACGCGCGCGCCCGAAGTCCGCGAGCTGTTTCAGAAGTTCGGGACGGTCGTCGAGTGCGATATCGTGCGTAACTACGGCTTCGTGCATTTGGACGCGACGGGCGATGTGAACGACGCTATCAAAGAGTTGAACGGTATGATGGTCGACGGACAGCCCATGAAGGTGCAGTTGTCGACGAGTCGTGTCCGGCAGCGGCCGGGCATGGGCGACCCCGAGCAGTGCTACCGCTGTGGCCGCGGGGGCCACTGGTCCAAGGAGTGCCCGAAGGCGCTGGGCCCCGACCGCAACGGTTTCCGCGATCGAGCGTTCGGCCGCGATCCCTACCCTCCGCCGCCGCCGCCACCCTTCCTTCGCGATCGCATGATGGGAGGATTTGGGGATCCATATGACGGGTACTATGATCGTTCACGGTTCGATTCTCCACGGGACTTGTTCGAGCGACGCTATCCAGTTGGAGGAGCATCACGAGGGCTGGAATTGGGCGGATCTAGAGGAGCTCGCGGTGACTTCGTTTCTCCGCCCTTACGCCGCGAACCCATGCCACCCATGCCTAATTTACCTCCACTGCGGAGCGGAATGGGTTCCATGAGATCTTCCTATGATCCTATGTACAGCCGCAGAAGCCCCCCACCAGGACCCCAGATGTCCAGAGGAATGTATGAAGATTTTAGCAGAGATACTTTTGATGACAGAAGGCCCGGAATGCGAGGTCCGTCGCCGTCAAGAAGATATGCGCCTTATTAA

Protein

MPGTGTFKIFIGNLSDKTTEADLRPLFEKYGTVVECDIVRNYGFVHMENEQVGREAIQNLNGELVHGQAIKIEAAKSRKAPSTPTTKIFVGNLTDKTRAPEVRELFQKFGTVVECDIVRNYGFVHLDATGDVNDAIKELNGMMVDGQPMKVQLSTSRVRQRPGMGDPEQCYRCGRGGHWSKECPKALGPDRNGFRDRAFGRDPYPPPPPPPFLRDRMMGGFGDPYDGYYDRSRFDSPRDLFERRYPVGGASRGLELGGSRGARGDFVSPPLRREPMPPMPNLPPLRSGMGSMRSSYDPMYSRRSPPPGPQMSRGMYEDFSRDTFDDRRPGMRGPSPSRRYAPY

Description

Essential RNA-binding protein. May be required for circadian repression of eclosion. Also essential for nurse cell dumping during oogenesis, the process whereby the cytoplasmic contents of nurse cells are transferred to the oocyte late in it's development.

Keywords

Biological rhythms   Complete proteome   Cytoplasm   Metal-binding   Nucleus   Phosphoprotein   Reference proteome   Repeat   RNA-binding   Zinc   Zinc-finger  

Feature

chain  RNA-binding protein lark

Uniprot

Q5I7M6   A0A2W1BNA5   A0A2H1VW38   H9JD13   A0A194QGB2   A0A194R6H5   + More
A0A212F8Q4   A0A0L7LMB3   S4PSE3   I4DNI9   A0A232ERZ6   A0A0T6B432   A0A158P347   A0A3L8E2Y9   A0A1W4WCS5   A0A1Y1NBR7   A0A0C9Q4C7   D6WX34   A0A067RJR6   T1E2T2   E9IIK8   A0A2J7Q914   E2C3J1   E2A1C4   V9IAR7   A0A087ZS91   A0A0J7KZR1   F4W4I1   Q16HL9   E0VDZ8   A0A023ER06   A0A2J7Q916   A0A0N0U6Z6   A0A310SKG0   A0A1Q3EXR0   A0A1B6E3Z8   J3JZK6   B0WPR2   A0A1B6DJH4   A0A2A3E0I8   A0A1L8DHC2   A0A182JP14   A0A182VDS6   A0A182TFW6   A0A182X5T1   A0A0E4G8F0   A0A182HW64   A0A182P5E8   A0A182YAX2   A0A182QPN4   A0A182MU34   A0A1B6L2Q5   A0A0K8TPM5   A0A1B6L474   A0A182R6M4   A0A182WDP6   A0A1Y9H271   A0A1B6IJD7   U5EZM9   A0A182SSF6   A0A0L0C683   A0A1B6GVW2   T1DIF1   A0A1B6K376   A0A1B6LHS2   A0A1B6LSQ5   A0A0K8UF30   A0A034WL04   A0A0A1XRY0   A0A0K8VZI3   A0A084W8B8   A0A1A9WS77   A0A1B0BAD2   A0A1B0FJ46   A0A1A9UXV2   A0A0Q9XDX9   A0A3B0JPX0   I7LTN7   A0A0P8YFZ0   T1PEY7   A0A1I8P3C6   A0A336MGR7   A0A0M3QW99   A0A0Q9WRU6   A0A0R1E1D6   A0A0J9UG35   Q94901   A0A336KP41   A0A1W4UTZ3   A0A0Q5U519   A0A2M3Z9Q9   A0A2M4BSP6   A0A2M4CGU5   A0A2M4CMH3   W5JV78   A0A0Q9WPY6  

Pubmed

30836863    28756777    19121390    26354079    22118469    26227816    + More
23622113    22651552    28648823    21347285    30249741    28004739    18362917    19820115    24845553    24330624    21282665    20798317    21719571    17510324    20566863    24945155    22516182    23537049    12364791    25244985    26369729    26108605    25348373    25830018    24438588    17994087    18057021    15632085    25315136    17550304    22936249    9120432    10731132    12537572    12537569    8307324    9491990    11560900    15452872    18327897    20920257    23761445   

EMBL

AY846357    MH745573    MH745574    AAW48898.1    QBM91280.1    QBM91281.1    + More
KZ150062    PZC74210.1    ODYU01004797    SOQ45049.1    BABH01027683    KQ459232    KPJ02491.1    KQ460685    KPJ12840.1    AGBW02009701    OWR50089.1    JTDY01000601    KOB76499.1    GAIX01000005    JAA92555.1    AK402957    BAM19479.1    NNAY01002529    OXU21130.1    LJIG01009929    KRT82098.1    ADTU01007748    ADTU01007749    QOIP01000001    RLU26813.1    GEZM01007761    JAV94948.1    GBYB01008913    JAG78680.1    KQ971361    EFA08785.1    KK852428    KDR24052.1    GALA01001015    JAA93837.1    GL763494    EFZ19608.1    NEVH01016943    PNF25080.1    GL452320    EFN77529.1    GL435760    EFN72750.1    JR036828    AEY57424.1    LBMM01001715    KMQ95851.1    GL887532    EGI70876.1    CH478160    EAT33739.1    DS235088    EEB11604.1    GAPW01002532    JAC11066.1    PNF25079.1    KQ435714    KOX79221.1    KQ760382    OAD60691.1    GFDL01015057    JAV19988.1    GEDC01004664    JAS32634.1    APGK01056684    APGK01056685    APGK01056686    BT128688    KB741277    KB631624    AEE63645.1    ENN71094.1    ERL84767.1    DS232028    EDS32471.1    GEDC01011444    JAS25854.1    KZ288486    PBC25238.1    GFDF01008222    JAV05862.1    AAAB01008816    HACL01000167    CFW94461.1    APCN01001469    AXCN02001743    AXCM01001638    GEBQ01022041    JAT17936.1    GDAI01001758    JAI15845.1    GEBQ01021469    JAT18508.1    GECU01020669    JAS87037.1    GANO01000493    JAB59378.1    JRES01000836    KNC27888.1    GECZ01003244    JAS66525.1    GALA01000976    JAA93876.1    GECU01002083    GECU01000466    JAT05624.1    JAT07241.1    GEBQ01016722    JAT23255.1    GEBQ01013254    JAT26723.1    GDHF01027085    GDHF01005016    JAI25229.1    JAI47298.1    GAKP01002731    GAKP01002730    JAC56221.1    GBXI01013197    GBXI01000627    JAD01095.1    JAD13665.1    GDHF01008032    JAI44282.1    ATLV01021410    KE525318    KFB46462.1    JXJN01010917    CCAG010018371    CH933809    KRG05865.1    KRG05866.1    OUUW01000002    SPP77520.1    CH379070    EAL30188.1    CH902618    KPU77848.1    KA647254    AFP61883.1    UFQS01000940    UFQT01000940    SSX07885.1    SSX28119.1    CP012525    ALC43773.1    CH940647    KRF84241.1    CM000159    KRK01331.1    KRK01332.1    CM002912    KMY98060.1    KMY98061.1    U59476    AE014296    AY061458    UFQS01000679    UFQT01000679    SSX06147.1    SSX26503.1    CH954178    KQS43324.1    GGFM01004526    MBW25277.1    GGFJ01006948    MBW56089.1    GGFL01000203    MBW64381.1    GGFL01002287    MBW66465.1    ADMH02000399    ETN66694.1    CH963847    KRF97759.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000037510    UP000215335    + More
UP000005205    UP000279307    UP000192223    UP000007266    UP000027135    UP000235965    UP000008237    UP000000311    UP000005203    UP000036403    UP000007755    UP000008820    UP000009046    UP000053105    UP000019118    UP000030742    UP000002320    UP000242457    UP000075881    UP000075903    UP000075902    UP000076407    UP000075840    UP000075885    UP000076408    UP000075886    UP000075883    UP000075900    UP000075920    UP000075884    UP000075901    UP000037069    UP000030765    UP000091820    UP000092460    UP000092444    UP000078200    UP000009192    UP000268350    UP000001819    UP000007801    UP000095301    UP000095300    UP000092553    UP000008792    UP000002282    UP000000803    UP000192221    UP000008711    UP000000673    UP000007798   

PRIDE

Q5I7M6    H9JD13    Q94901   

Pfam

PF00076   RRM_1        + More
PF00098   zf-CCHC
PF00294   PfkB

Interpro

IPR001878   Znf_CCHC        + More
IPR035979   RBD_domain_sf       
IPR000504   RRM_dom       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR029056   Ribokinase-like       
IPR001805   Adenokinase       
IPR011611   PfkB_dom       
IPR002173   Carboh/pur_kinase_PfkB_CS       

SUPFAM

SSF54928   SSF54928        + More
SSF53613   SSF53613       

Gene 3D

3.30.70.330     3.40.1190.20    

ProteinModelPortal

Q5I7M6   A0A2W1BNA5   A0A2H1VW38   H9JD13   A0A194QGB2   A0A194R6H5   + More
A0A212F8Q4   A0A0L7LMB3   S4PSE3   I4DNI9   A0A232ERZ6   A0A0T6B432   A0A158P347   A0A3L8E2Y9   A0A1W4WCS5   A0A1Y1NBR7   A0A0C9Q4C7   D6WX34   A0A067RJR6   T1E2T2   E9IIK8   A0A2J7Q914   E2C3J1   E2A1C4   V9IAR7   A0A087ZS91   A0A0J7KZR1   F4W4I1   Q16HL9   E0VDZ8   A0A023ER06   A0A2J7Q916   A0A0N0U6Z6   A0A310SKG0   A0A1Q3EXR0   A0A1B6E3Z8   J3JZK6   B0WPR2   A0A1B6DJH4   A0A2A3E0I8   A0A1L8DHC2   A0A182JP14   A0A182VDS6   A0A182TFW6   A0A182X5T1   A0A0E4G8F0   A0A182HW64   A0A182P5E8   A0A182YAX2   A0A182QPN4   A0A182MU34   A0A1B6L2Q5   A0A0K8TPM5   A0A1B6L474   A0A182R6M4   A0A182WDP6   A0A1Y9H271   A0A1B6IJD7   U5EZM9   A0A182SSF6   A0A0L0C683   A0A1B6GVW2   T1DIF1   A0A1B6K376   A0A1B6LHS2   A0A1B6LSQ5   A0A0K8UF30   A0A034WL04   A0A0A1XRY0   A0A0K8VZI3   A0A084W8B8   A0A1A9WS77   A0A1B0BAD2   A0A1B0FJ46   A0A1A9UXV2   A0A0Q9XDX9   A0A3B0JPX0   I7LTN7   A0A0P8YFZ0   T1PEY7   A0A1I8P3C6   A0A336MGR7   A0A0M3QW99   A0A0Q9WRU6   A0A0R1E1D6   A0A0J9UG35   Q94901   A0A336KP41   A0A1W4UTZ3   A0A0Q5U519   A0A2M3Z9Q9   A0A2M4BSP6   A0A2M4CGU5   A0A2M4CMH3   W5JV78   A0A0Q9WPY6  

PDB

2DNQ     E-value=3.57853e-18,     Score=224

KEGG

692732    K13187 RNA-binding protein 4 | (RefSeq) Lark; RNA-binding protein lark

GO

GO:0008270   GO:0003723   GO:0005634   GO:0006166   GO:0004001   GO:0008062   GO:2000767   GO:0007303   GO:0042752   GO:0008104   GO:0045804   GO:0045995   GO:0005829   GO:0009792   GO:0030036   GO:0045475   GO:0000398   GO:0071011   GO:0005737   GO:0007623   GO:0071013   GO:0007562   GO:0000278   GO:0003729   GO:0016021   GO:0000166   GO:0003676   GO:0004707   GO:0051539   GO:0009451   GO:0007155   GO:0051015   GO:0003779  

Subcellular location

Cytoplasm  
Nucleus  

Length:

343

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00534

outside

1  -  343

 

 

Pi

322.222599

Theta

237.282537

Tajima's D

1.085085

CLR

0

CSRT

0.68131593420329

Interpretation

Uncertain