Silkworm Genome Informatics Database

Gene

KWMTBOMO01063 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007358

Annotation

c-Jun_NH2-terminal_kinase_[Bombyx_mori]

Location

Bomo_Chr3(-):1368219-1390205 View in EpiBrowser

Full name

Mitogen-activated protein kinase

Location in the cell

Mitochondrial Reliability : 1.704 Nuclear Reliability : 1.211

CDS

ATGTCGGCCCCGCCGCGCCACCCACACTTTTATACCGTTGAGGTCGGCGACACACGCTTCACCATCCTCAAGCGCTACCAGAACCTCAAACCCATCGGCTCCGGCGCCCAGGGTATTGTATGTGCCGCATACGACACGGTGACGCAACAGAATGTTGCCATAAAGAAGTTGTCGCGTCCGTTTCAGAACGTGACGCACGCGAAAAGAGCTTACAGGGAGTTCAAACTTATGAAACTTGTCAACCATAAAAATATAATCGGATTGCTAAACGCGTTCACGCCGCAGAAAAGCCTCGAGGAATTCCAAGACGTGTATCTGGTTATGGAGCTGATGGACGCTAATCTGTGCCAAGTGATTCAGATGGATCTGGATCACGAACGGATGAGCTATCTGCTGTACCAGATGCTGTGCGGCATCAAACACTTGCACCTCGCCGGAATCATTCATCGGGATCTGAAGCCGTCCAACATAGTGGTGAAGAGCGACTGCACGCTGAAGATCCTGGACTTCGGGCTGGCTCGCACCGCCGGGACCACCTTCATGATGACGCCCTACGTCGTCACGCGCTACTACCGCGCGCCGGAGGTGATCTTGGGTATGGGCTACACCGAGAACGTGGACATCTGGTCCGTGGGCTGCATCATGGGGGAGATGATCCGCGGCGGCGTGCTGTTCCCCGGCACCGACCACATCGACCAGTGGAACAAGATCATCGAGCAACTGGGCACGCCGTCGGCCGCGTTCATGTCCCGGCTGCAGCCCACGGTCCGCAACTACGTCGAGAACAGACCGCGCTACTCCGGGTACAGCTTCGAGCGGCTCTTCCCGGACATACTGTTCCCCAGCGACAGCAACGAGCACAACCGACTCAAGGCGTCGCAGGCCCGCGACCTGTTGTCGCGCATGCTGGTCATCGACCCCGAGCGCCGCATCTCAGTGGACGACGCCCTGCTGCATCCCTACATCAACGTGTGGTACGACGAGGTAGAGGTCAACGCGCCCGCACCGGCCTCATACGACCACTCGGTGGACGAACGCGAGCACACCGTGGAGCAGTGGAAGCAGCTCATCTACCAGGAGGTGGTCGAGTACTCCGCGCCGCCCCACCCCCCGCCCCCGCACCCCCCGCCCGCCGACCACGCGCAGCCCGCACTCACCACGTAG

Protein

MSAPPRHPHFYTVEVGDTRFTILKRYQNLKPIGSGAQGIVCAAYDTVTQQNVAIKKLSRPFQNVTHAKRAYREFKLMKLVNHKNIIGLLNAFTPQKSLEEFQDVYLVMELMDANLCQVIQMDLDHERMSYLLYQMLCGIKHLHLAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTTFMMTPYVVTRYYRAPEVILGMGYTENVDIWSVGCIMGEMIRGGVLFPGTDHIDQWNKIIEQLGTPSAAFMSRLQPTVRNYVENRPRYSGYSFERLFPDILFPSDSNEHNRLKASQARDLLSRMLVIDPERRISVDDALLHPYINVWYDEVEVNAPAPASYDHSVDEREHTVEQWKQLIYQEVVEYSAPPHPPPPHPPPADHAQPALTT

Catalytic Activity

ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]

Uniprot

A7BJ75 A0A2W1BFI3 F6M734 A0A194QBX3 H9JCW1 A0A1B6DQH9 + More
A0A2J7PXI6 A0A1B6KZP9 A0A2H1VNG7 A0A222AJ96 D4AHR8 A0A310SK00 A0A182YG03 D6WV90 A0A067RGE7 A0A2M4ARA9 A0A084VPQ8 Q7QG32 A0A1B1UZE8 A0A023GM25 A0A2A3EFK0 A0A1E1X902 A0A212EUW4 A0A0A9X6V3 A0A1S4FKB3 S4SE26 K7IRE7 A0A151XDA4 B0W264 A0A1W4W8J5 A0A088AW89 A0A158NH21 A0A026VYR3 A0A195D186 A0A2L2XVM8 A0A224YRX4 A0A131YYR1 L7M7L8 A0A131XJW6 E2AJD5 A0A3G1VVR7 A0A0N7ZCG2 A0A224XRH1 A0A0M5L8B2 A0A0X7YPR7 A0A1L8DKL2 A0A087TIT4 J9JVH9 A0A0L7R4Z0 A0A1Z5KXF3 A0A293MVG4 A0A2R5LKL6 E0VE35 A0A232EV43 A0A182LWR1 A0A2P2I2L9 B7Q122 A0A1L6UW77 A0A182Q8U8 A0A182JMY4 A0A1D2MF94 A0A2J7PXK9 A0A1B6E9F6 A0A034WDG1 A0A0K8W4J9 A0A0A1WTM6 W8AKY4 G9DCS6 T1P976 E2B2C2 A0A0K8TRC8 A0A226ES80 A0A1L6UW84 A0A0K2UFU1 A0A1I8PS27 T1G7A1 A0A1Y1N8L0 A0A1B6KUG8 A0A1B0GAM6 A0A1A9UIP0 A0A1B0BUT5 A0A146LQ00 T1HU71 A0A182RGB4 A0A023F5Y5 A0A0V0GAR8 A0A336KSW2 A0A0C5G5S8 A0A1W4WK31 A0A2M3ZBI6 A0A2M4ARW0 W5J7C7 V5GSJ6 A0A0A9XF50 A0A2S2QXR6 B3N947 A0A2H4V6A5 A0A2H8TNG3 A0A2S2NVD6 B3MPN7

EC Number

2.7.11.24

Pubmed

17913811 28756777 26354079 19121390 25244985 18362917 + More
19820115 24845553 24438588 12364791 14747013 17210077 28503490 22118469 25401762 26823975 17510324 20075255 21347285 24508170 30249741 26561354 28797301 26830274 25576852 28049606 20798317 28528879 20566863 28648823 28012735 27289101 25348373 25830018 24495485 23807503 25315136 26369729 23254933 28004739 25474469 20920257 23761445 17994087

EMBL

AB302934 BAF75352.1 KZ150083 PZC73832.1 JF727877 AEE81067.1 + More
KQ459232 KPJ02490.1 BABH01027676 GEDC01009354 JAS27944.1 NEVH01020856 PNF21055.1 GEBQ01023087 JAT16890.1 ODYU01003480 SOQ42337.1 KY609688 ASO76455.1 AB523402 BAI87826.1 KQ761783 OAD57006.1 KQ971363 EFA09273.1 KK852699 KDR18179.1 GGFK01009989 MBW43310.1 ATLV01015027 KE524999 KFB39952.1 AAAB01008839 EAA05905.3 KX428484 ANW09595.1 GBBM01001240 JAC34178.1 KZ288256 PBC30535.1 GFAC01003441 JAT95747.1 AGBW02012284 OWR45290.1 GBHO01027900 GDHC01014090 JAG15704.1 JAQ04539.1 JQ291732 AFN26248.1 KQ982294 KYQ58351.1 DS231825 EDS28192.1 ADTU01015453 ADTU01015454 ADTU01015455 ADTU01015456 KK107566 QOIP01000006 EZA48912.1 RLU21971.1 KQ976973 KYN06668.1 IAAA01007217 IAAA01007218 IAAA01007219 LAA00161.1 GFPF01009222 MAA20368.1 GEDV01004233 JAP84324.1 GACK01004738 JAA60296.1 GEFH01002096 JAP66485.1 GL439972 EFN66456.1 MG756654 AYK28495.1 GDRN01067506 GDRN01067504 JAI64360.1 GFTR01005683 JAW10743.1 KR075821 ALE20540.1 KC900087 AHG95993.1 GFDF01007133 JAV06951.1 KK115399 KFM65023.1 ABLF02031100 KQ414654 KOC65950.1 GFJQ02007332 JAV99637.1 GFWV01020105 MAA44833.1 GGLE01005731 MBY09857.1 DS235088 EEB11641.1 NNAY01002053 OXU22231.1 AXCM01012935 IACF01002632 LAB68278.1 ABJB010367667 ABJB010651218 ABJB010727238 DS835548 EEC12544.1 KY283809 APS85778.1 AXCN02000852 AXCN02000853 LJIJ01001474 ODM91623.1 PNF21056.1 GEDC01028228 GEDC01023448 GEDC01002773 JAS09070.1 JAS13850.1 JAS34525.1 GAKP01006258 JAC52694.1 GDHF01006176 GDHF01000248 JAI46138.1 JAI52066.1 GBXI01012452 GBXI01004159 JAD01840.1 JAD10133.1 GAMC01020075 GAMC01020073 JAB86482.1 JF905627 AEI27292.1 KA644710 AFP59339.1 GL445130 EFN90159.1 GDAI01000674 JAI16929.1 LNIX01000002 OXA59924.1 KY283817 APS85786.1 HACA01019732 CDW37093.1 AMQM01007501 KB097628 ESN93255.1 GEZM01009831 GEZM01009830 GEZM01009829 GEZM01009828 GEZM01009827 GEZM01009826 GEZM01009825 GEZM01009824 GEZM01009823 JAV94284.1 GEBQ01024936 GEBQ01011283 JAT15041.1 JAT28694.1 CCAG010011281 JXJN01020918 JXJN01020919 GDHC01008671 JAQ09958.1 ACPB03007804 ACPB03007805 GBBI01002105 JAC16607.1 GECL01001252 JAP04872.1 UFQS01000682 UFQT01000682 UFQT01002857 SSX06173.1 SSX26529.1 SSX34172.1 KP071319 AJP08639.1 GGFM01005100 MBW25851.1 GGFK01010151 MBW43472.1 ADMH02002093 ETN59298.1 GALX01003889 JAB64577.1 GBHO01027901 GBHO01027899 GBRD01012996 GDHC01001736 JAG15703.1 JAG15705.1 JAG52830.1 JAQ16893.1 GGMS01013364 MBY82567.1 CH954177 EDV58482.1 MF588964 AUB45144.1 GFXV01003902 MBW15707.1 GGMR01008531 MBY21150.1 CH902620 EDV32285.2

Proteomes

UP000053268 UP000005204 UP000235965 UP000076408 UP000007266 UP000027135 + More
UP000030765 UP000007062 UP000242457 UP000007151 UP000002358 UP000075809 UP000002320 UP000192223 UP000005203 UP000005205 UP000053097 UP000279307 UP000078542 UP000000311 UP000054359 UP000007819 UP000053825 UP000009046 UP000215335 UP000075883 UP000001555 UP000075886 UP000075880 UP000094527 UP000095301 UP000008237 UP000198287 UP000095300 UP000015101 UP000092444 UP000078200 UP000092460 UP000015103 UP000075900 UP000000673 UP000008711 UP000007801

PRIDE

A7BJ75 H9JCW1

Pfam

PF00069 Pkinase

Interpro

IPR008271   Ser/Thr_kinase_AS        + More
IPR008351   MAPK_JNK
IPR011009   Kinase-like_dom_sf
IPR000719   Prot_kinase_dom
IPR003527   MAP_kinase_CS

SUPFAM

SSF56112 SSF56112

ProteinModelPortal

A7BJ75 A0A2W1BFI3 F6M734 A0A194QBX3 H9JCW1 A0A1B6DQH9 + More
A0A2J7PXI6 A0A1B6KZP9 A0A2H1VNG7 A0A222AJ96 D4AHR8 A0A310SK00 A0A182YG03 D6WV90 A0A067RGE7 A0A2M4ARA9 A0A084VPQ8 Q7QG32 A0A1B1UZE8 A0A023GM25 A0A2A3EFK0 A0A1E1X902 A0A212EUW4 A0A0A9X6V3 A0A1S4FKB3 S4SE26 K7IRE7 A0A151XDA4 B0W264 A0A1W4W8J5 A0A088AW89 A0A158NH21 A0A026VYR3 A0A195D186 A0A2L2XVM8 A0A224YRX4 A0A131YYR1 L7M7L8 A0A131XJW6 E2AJD5 A0A3G1VVR7 A0A0N7ZCG2 A0A224XRH1 A0A0M5L8B2 A0A0X7YPR7 A0A1L8DKL2 A0A087TIT4 J9JVH9 A0A0L7R4Z0 A0A1Z5KXF3 A0A293MVG4 A0A2R5LKL6 E0VE35 A0A232EV43 A0A182LWR1 A0A2P2I2L9 B7Q122 A0A1L6UW77 A0A182Q8U8 A0A182JMY4 A0A1D2MF94 A0A2J7PXK9 A0A1B6E9F6 A0A034WDG1 A0A0K8W4J9 A0A0A1WTM6 W8AKY4 G9DCS6 T1P976 E2B2C2 A0A0K8TRC8 A0A226ES80 A0A1L6UW84 A0A0K2UFU1 A0A1I8PS27 T1G7A1 A0A1Y1N8L0 A0A1B6KUG8 A0A1B0GAM6 A0A1A9UIP0 A0A1B0BUT5 A0A146LQ00 T1HU71 A0A182RGB4 A0A023F5Y5 A0A0V0GAR8 A0A336KSW2 A0A0C5G5S8 A0A1W4WK31 A0A2M3ZBI6 A0A2M4ARW0 W5J7C7 V5GSJ6 A0A0A9XF50 A0A2S2QXR6 B3N947 A0A2H4V6A5 A0A2H8TNG3 A0A2S2NVD6 B3MPN7

PDB

5AWM E-value=0, Score=1728

KEGG

100126162 K04440 mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24] | (RefSeq) J

PATHWAY

GO

GO:0004707 GO:0005524 GO:0035556 GO:0004705 GO:0010468 GO:0071310 GO:0005634 GO:0005737 GO:0007254 GO:0016319 GO:1903688 GO:0071276 GO:0048675 GO:0048615 GO:0010628 GO:0048674 GO:0071907 GO:0034614 GO:0043652 GO:0035313 GO:0071243 GO:0048010 GO:0007395 GO:0030424 GO:0009408 GO:0030425 GO:0046529 GO:0048803 GO:0010508 GO:0043508 GO:0007616 GO:0046844 GO:0007411 GO:0046843 GO:0035006 GO:0019731 GO:1904801 GO:0004672 GO:0006468 GO:0051539 GO:0009451 GO:0007155 GO:0051015 GO:0003779 GO:0016021

Length:

387

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0842

Exp number, first 60 AAs:

0.00418

Total prob of N-in:

0.00458

outside

1 - 387

Pi

194.312162

Theta

157.027687

Tajima's D

0.787468

CLR

0.177906

CSRT

0.6023198840058

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics