Gene

KWMTBOMO01046

Pre Gene Modal

BGIBMGA007367

Annotation

PREDICTED:_nucleoside_diphosphate_kinase_6-like_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr3(-):1117937-1119475      View in EpiBrowser

Full name

Nucleoside diphosphate kinase       + More
Nucleoside diphosphate kinase 6      

Alternative Name

Inhibitor of p53-induced apoptosis-alpha
nm23-H6
nm23-M6

Location in the cell

Mitochondrial   Reliability : 3.065

CDS

ATGCAAAAGCTTCAGCTAACATTAGCGATAGTAAAACCCCACGCCGTTAAGAATCCTATAGCATTATCATACATCCGACAAGCTGTAAAGAGCAAATTCGTTGTTATAAAAACTAAAAGAATATTGTTGGATGAAGACACTGCAGCAAAGTTTTATAGAGAGCATGTAGGGAAGTTCTTTTACAACCGTCTAGTCACATTTATGGCCAGTGGCTGCATAGATTTGCATATCCTTGGACACATGAGAGCAATACAGATGTGGAGAAAAATGCTAGGTCCCACAAGTGTATACAAAGCACAGTTCCAAGACCCGTACTGTCTCAGGGGGCTGTTTGGTATTTCAGATACAAGGAATGTTGCACATGGTTCAGATTCCCCTCAATCAGCAGAAAAGGAGATCAAATTCTTTTTCCCAGATTTCTCCATGTATCAGTGGTATAATGATGATGAACCCTGCTACAGGAAAGGACCAATAATATTCAACAGCCACTTGTTTCAACATGTTAGAAGATTATAG

Protein

MQKLQLTLAIVKPHAVKNPIALSYIRQAVKSKFVVIKTKRILLDEDTAAKFYREHVGKFFYNRLVTFMASGCIDLHILGHMRAIQMWRKMLGPTSVYKAQFQDPYCLRGLFGISDTRNVAHGSDSPQSAEKEIKFFFPDFSMYQWYNDDEPCYRKGPIIFNSHLFQHVRRL

Catalytic Activity

a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP
a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP

Cofactor

Mg(2+)

Similarity

Belongs to the NDK family.

Keywords

Alternative splicing   Apoptosis   ATP-binding   Complete proteome   Kinase   Magnesium   Metal-binding   Nucleotide metabolism   Nucleotide-binding   Reference proteome   Transferase  

Feature

chain  Nucleoside diphosphate kinase 6
splice variant  In isoform 3.

Uniprot

H9JCX0   A0A2W1BJE4   A0A2A4J3K8   A0A2H1VZJ4   A0A194QBV6   A0A194RAD7   + More
A0A232EI29   K7IXC1   A0A1B0DNJ9   A0A1B0C9M4   A0A0T6AZY1   A0A1Y1NG14   A0A1L8DKD5   J3JWT6   A0A026VWZ3   A0A067QQH4   A0A2K5R6Q5   A0A2K6SNI5   A0A2K6SNL9   A0A2K5R6N9   A0A0L7RE80   A0A2J8PA38   A0A2J8TFV8   C9J9V6   A0A2K6LFH9   A0A340W9V0   A0A2J8TG72   A0A2K5C826   A0A2J8TFU3   A0A2I2YRA6   A0A2I3HWM5   A0A2R9BF56   K7ET49   A0A2J8PA11   O75414   A0A2J8PA20   A0A2K5YP74   A0A2K5YP76   A0A0D9RTP2   A0A2K5KSH1   A0A096MQT0   A0A2I3GVM1   H2PAV2   K7BNT0   A0A0C4DG91   G1SDJ1   A0A383Z172   A0A341BYC9   A0A2U4CAY6   A0A2Y9N7H9   A0A1U7TTP1   A0A341BYX4   A0A0L7LQ67   L8HTL1   A0A2K6ALU3   G8F304   G7MIQ7   G3HKQ3   F1MCI2   E1ZZR2   F7DSK4   H9GDS3   A0A2U3XNX9   A0A2Y9GTW5   A0A195FG42   A0A2K5K5X1   W5NSJ6   A0A2K6NZS1   A0A158NGJ4   F6UCZ5   A0A2K6FAG3   A0A2K6FAH0   A0A2F0BAH0   A0A2R8MFV5   A0A2U3VV03   A0A2Y9F5H1   G3U1F4   A0A151XF51   A0A195E751   U6CTK3   A0A3P4KFX2   A0A2Y9J0A1   E0VDW9   A0A0N0U447   F1SKM8   G9KDJ3   A0A2Y9QSZ2   A0A0P4VVY6   S9XM34   A0A1W7RA72   A0A3M0ITI4   M3YU52   W5NJ53   D2HTY7   A0A1W4WQ97   A0A218UAJ4   A0A2A3E7H8   A0A091DQA3   O88425  

EC Number

2.7.4.6

Pubmed

19121390    28756777    26354079    28648823    20075255    28004739    + More
22516182    23537049    24508170    30249741    24845553    16641997    21269460    25944712    22398555    22722832    16136131    10453732    14702039    15489334    11181995    21993624    26227816    22751099    17194215    22002653    17431167    21804562    19393038    20798317    21881562    20809919    25362486    21347285    20566863    30723633    23236062    23149746    20010809    21183079   

EMBL

BABH01027655    KZ150083    PZC73815.1    NWSH01003655    PCG65983.1    ODYU01005428    + More
SOQ46259.1    KQ459232    KPJ02475.1    KQ460685    KPJ12826.1    NNAY01004368    OXU17994.1    AAZX01006137    AJVK01017623    AJWK01002474    LJIG01016435    KRT80610.1    GEZM01003570    JAV96719.1    GFDF01007151    JAV06933.1    APGK01058543    BT127704    KB741291    AEE62666.1    ENN70514.1    KK107673    QOIP01000006    EZA48145.1    RLU21157.1    KK853043    KDR12120.1    KQ414612    KOC69134.1    NBAG03000218    PNI80873.1    NDHI03003498    PNJ31941.1    AC105267    PNJ31933.1    PNJ31931.1    CABD030021190    ADFV01172947    AJFE02063041    ABGA01071875    AACZ04000306    PNI80865.1    AF051941    U90449    AK294809    AK297364    AK222555    BC001808    BC012828    PNI80875.1    AQIB01131778    AHZZ02020182    GABF01006376    JAA15769.1    PNI80872.1    CH471055    EAW64861.1    AAGW02044054    JTDY01000360    KOB77549.1    JH883489    ELR46367.1    AQIA01039517    AB172966    JH330210    BAE90028.1    EHH61668.1    JSUE03023787    CM001254    EHH16399.1    JH000468    EGV92142.1    GL435511    EFN73333.1    AAWZ02032679    KQ981625    KYN38994.1    AMGL01045691    ADTU01015010    NTJE010118098    MBV99977.1    KQ982201    KYQ59016.1    KQ979568    KYN21018.1    HAAF01001067    CCP72893.1    CYRY02000392    VCW49905.1    DS235088    EEB11575.1    KQ435840    KOX71458.1    AEMK02000086    DQIR01255697    DQIR01298347    HDC11175.1    JP014370    AES02968.1    GDRN01109909    JAI57003.1    KB019908    EPY72695.1    GFAH01000373    JAV48016.1    QRBI01000256    RMB90173.1    AEYP01051164    AEYP01051165    AHAT01033791    ACTA01035720    GL193373    EFB18707.1    MUZQ01000514    OWK50686.1    KZ288344    PBC27665.1    KN122104    KFO33222.1    AF051942    BC002007   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000215335    UP000002358    + More
UP000092462    UP000092461    UP000019118    UP000053097    UP000279307    UP000027135    UP000233040    UP000233220    UP000053825    UP000005640    UP000233180    UP000265300    UP000233020    UP000001519    UP000001073    UP000240080    UP000001595    UP000002277    UP000233140    UP000029965    UP000233060    UP000028761    UP000001811    UP000261681    UP000252040    UP000245320    UP000248483    UP000189704    UP000037510    UP000233120    UP000009130    UP000233100    UP000006718    UP000001075    UP000009136    UP000000311    UP000001646    UP000245341    UP000248481    UP000078541    UP000233080    UP000002356    UP000233200    UP000005205    UP000008225    UP000233160    UP000245340    UP000248484    UP000007646    UP000075809    UP000078492    UP000248482    UP000009046    UP000053105    UP000008227    UP000248480    UP000269221    UP000000715    UP000018468    UP000008912    UP000192223    UP000197619    UP000242457    UP000028990    UP000000589   

PRIDE

H9JCX0    C9J9V6    O75414    G3HKQ3    O88425   

Pfam

PF00334   NDK        + More
PF00149   Metallophos

Interpro

IPR001564   Nucleoside_diP_kinase        + More
IPR034907   NDK-like_dom       
IPR036850   NDK-like_dom_sf       
IPR023005   Nucleoside_diP_kinase_AS       
IPR037994   NDPk6       
IPR012337   RNaseH-like_sf       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR029052   Metallo-depent_PP-like       
IPR033308   PGAP5/Cdc1/Ted1       

SUPFAM

SSF54919   SSF54919        + More
SSF53098   SSF53098       

Gene 3D

3.30.70.141     3.60.21.10    

CDD

cd04414  NDPk6

ProteinModelPortal

H9JCX0   A0A2W1BJE4   A0A2A4J3K8   A0A2H1VZJ4   A0A194QBV6   A0A194RAD7   + More
A0A232EI29   K7IXC1   A0A1B0DNJ9   A0A1B0C9M4   A0A0T6AZY1   A0A1Y1NG14   A0A1L8DKD5   J3JWT6   A0A026VWZ3   A0A067QQH4   A0A2K5R6Q5   A0A2K6SNI5   A0A2K6SNL9   A0A2K5R6N9   A0A0L7RE80   A0A2J8PA38   A0A2J8TFV8   C9J9V6   A0A2K6LFH9   A0A340W9V0   A0A2J8TG72   A0A2K5C826   A0A2J8TFU3   A0A2I2YRA6   A0A2I3HWM5   A0A2R9BF56   K7ET49   A0A2J8PA11   O75414   A0A2J8PA20   A0A2K5YP74   A0A2K5YP76   A0A0D9RTP2   A0A2K5KSH1   A0A096MQT0   A0A2I3GVM1   H2PAV2   K7BNT0   A0A0C4DG91   G1SDJ1   A0A383Z172   A0A341BYC9   A0A2U4CAY6   A0A2Y9N7H9   A0A1U7TTP1   A0A341BYX4   A0A0L7LQ67   L8HTL1   A0A2K6ALU3   G8F304   G7MIQ7   G3HKQ3   F1MCI2   E1ZZR2   F7DSK4   H9GDS3   A0A2U3XNX9   A0A2Y9GTW5   A0A195FG42   A0A2K5K5X1   W5NSJ6   A0A2K6NZS1   A0A158NGJ4   F6UCZ5   A0A2K6FAG3   A0A2K6FAH0   A0A2F0BAH0   A0A2R8MFV5   A0A2U3VV03   A0A2Y9F5H1   G3U1F4   A0A151XF51   A0A195E751   U6CTK3   A0A3P4KFX2   A0A2Y9J0A1   E0VDW9   A0A0N0U447   F1SKM8   G9KDJ3   A0A2Y9QSZ2   A0A0P4VVY6   S9XM34   A0A1W7RA72   A0A3M0ITI4   M3YU52   W5NJ53   D2HTY7   A0A1W4WQ97   A0A218UAJ4   A0A2A3E7H8   A0A091DQA3   O88425  

PDB

5X00     E-value=1.57871e-18,     Score=223

KEGG

101739864    K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] | (RefSeq) nucleoside diphosphate kinase 6-like

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
00240    Pyrimidine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0006228   GO:0006241   GO:0004550   GO:0006183   GO:0005524   GO:0006915   GO:0045839   GO:0030308   GO:0046872   GO:0005739   GO:0006506   GO:0016021   GO:0016787   GO:0006165   GO:0005856   GO:0007155   GO:0051015   GO:0003779  

PANTHER

PTHR13315  

Length:

171

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

12.89049

Exp number, first 60 AAs:

1.06116

Total prob of N-in:

0.52574

outside

1  -  171

 

 

Pi

26.924643

Theta

27.98064

Tajima's D

-0.898454

CLR

235.631494

CSRT

0.153042347882606

Interpretation

Uncertain