Silkworm Genome Informatics Database

Gene

KWMTBOMO01019 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA007386

Annotation

PREDICTED:_ubiquitin_carboxyl-terminal_hydrolase_16_[Bombyx_mori]

Location

Bomo_Chr3(+):89076-99340 View in EpiBrowser

Full name

Ubiquitinyl hydrolase 1

Location in the cell

Nuclear Reliability : 4.223

CDS

ATGGTTAAAAAAAAGAGACAGAGCGACCCTGGAGAAAATGGAGACGAATCAACAGAGTCTTGCGAAGAGAACGTAAAATCCGCATGTCCTCACGTCGCGAAAGCAGTAGATCTGACTCGGCTAAAGAAAGCTATTAAAATCGGAGGATTTGAAAAAGAATGTTCAGAGTGCAAAAAAGTTGCAAAAACTGAGGTACTTGATCCAGATTTTGAAGAAGATTTGTCCTTGTGGATGTGTTTACGTTGTGGCACGCAACTCTGTGGCCGAACACGCAATAAACATGCTCTAAATCACTTCAACACGCCTCATTCTGACTGCCATGCTCTCGCTGCTAATTCCACCACCTGGGAAATCTACTGTTACAACTGTAATAATGAAGTTACTGCATCAACAGCCAAAAAACTCCATGAGTGCATAGAGTACCTCAAGAAGCAGTTCCTGGCCAGTAGCACTGTTAAATCATTGCCCCCTATTGAGTTACCATTTGAAACTAAAGACTTCTCTATTATAGAAACTATATCAAAGGATCCCCTATCAAAAGGAAAAGATAAGGCAATGGTTAATTTAGGCCGTGTTAGAGGTCTAAGTAATTTAGGAAATACATGTTTTTTTAATTCTGTTATGCAATGCTTAGTTCAAACCCCATATCTATTAAAAGTATTGCAAGAGATGTCTGTGCCAGGAGAAAAGTTCAAGTTACCAGGAGGAAAACTCAAGCTGAGAGGAGATGCAGGTGAATTAAAAGATGTTGATCTACCCCCTATAGCTGGCCAGTTGGGAGAGTGGGGAACATTAACAAGGACTTTAGCAGAAACATTAGAGGAATTACAGGGAGGTGAGGGTGGGGTTTACACTCCAAGGAAGTTATTATCGGCACTGGTTAATAAACTCCCTCAATTTGGAGGAGGAGACCAACATGATGCACATGAACTACTAAGGCATTTGCTAGAAGCTGTCAGATCAGAGGATCTACGCCGCTACCAATCGGTGATTCTGAGCAGTTTGGGAATGAATTCAAAGGTGGACCCTGCAAAAGTGGATGGAGAAGTCAAACAAAAGGTCAAGTTTTATGGTCAACAGGCTTCGGACACAATGCTCAGGCCCGAACAGGTATTCCGTGGCTTTCTAGTTTCGACCTTGGAATGTCAAGATTGCCTCCACCAATCAGACAGAGCTGAATATTTTTTGGATTTGTCTCTCCCAGTCGCGGCATGTCGTCCTCAACCCCCGGCCGTAGCCAGGAGAAAAACTCCTAATGAAAATGCGTACAATACTCAAGAAGAGAATAAGCCTTCGAAGCATCAGCTCAAGAAAGAACGGATCGCCGCTCGGAAAGCAGCCCGGAAGAACAAAGGAGCCGCGGGCGAGGGCGGCGCCGACACCAGCGGGCCCGCCAAGGAGGACGGCAACTCCTCCTCCGAGCAGTCCGACGCCGACGTGGAGGACAACCTGGAGGAGCAGCCGCGGCCCGGCCCCGCGCTCGCGCACACCGCCGCCAACTTCGCCGTCTACCACATGGAGTCCGGCTACAACTCGGAGAAGGTCATCAGCGCAGACTCCATCCGCACCAGCCCCGTTCATCTCGACAAGGAGAAGGCCGACAACACTCCGGAACGCACCGACAAGGACGGGCCCCCCGTCGCCATCCCGCTCCAGTACGAGCCGCTCGAGAACCTGTCCAACCCTGATTCCGGAGTCGCCAGCCCCGAGGCCACCAAGCACAACTCCACCGAGACCGTCCACGACGAGCCCTCGCCCGTCAAGCCGGAGTACGAGAGGCCCGCCTCCAGAATATCCTTCGCACCGGAGTACACCAACGAACTCGTTTCCCGGGGGATCAGCGTCCAGGGGTGCCGCAACCTGCTGGAGAACAGCGTCGACAACAGCTACGACTCTCTCCTCGAAACCAAGACGCTCAACGAACTCAACGAGCAACTCGACAACCTGTACCTGGAGGAGCCTCCCCCTCCTGCGCCGCAGCCCCGGCCCGCGCCCCCCTCCCCGCGCTACGTGTGCGACGAGGACGAGTGCAGCGTGCACTCCTGCCTCGCGCAGTTCACGGCGCTCGAGCTGCTCACGGGCAACAACAAGGTCGGCTGCGAGCTGTGCACCGAGCGCGTCAACGGCAAGGGCGGGAAGACGATCTACACAAACGCGACGAAGCGGTTCCTGGTGTCCAGCCCGCCCGCCGTCCTCATCCTGCACCTCAAGCGGTTCCAGATCGGGCCGCGATGCATGTTCCGCAAGATGTCGAAGCACGTGGACTTCCCGACCGTCCTGGACCTGGCGCCCTTCTGCGCCATGGACAAGGTGCGCGGCCAGGCCTCGCTGCTGTACGCGCTCCCCGACTCGGACCTGTCCGGCTACGAGTCCGGCGAGGCGGCGGCGGCCGAGCCCCCCGCCGGCCGCTGGTACTACGTGTCGGACAGCATGGTGTCGGAAGTCAGCGAAGACAAGGTGTTGAGGGCGCAGGCCTACCTGCTCTTCTACGAGAGGATATTATAG

Protein

MVKKKRQSDPGENGDESTESCEENVKSACPHVAKAVDLTRLKKAIKIGGFEKECSECKKVAKTEVLDPDFEEDLSLWMCLRCGTQLCGRTRNKHALNHFNTPHSDCHALAANSTTWEIYCYNCNNEVTASTAKKLHECIEYLKKQFLASSTVKSLPPIELPFETKDFSIIETISKDPLSKGKDKAMVNLGRVRGLSNLGNTCFFNSVMQCLVQTPYLLKVLQEMSVPGEKFKLPGGKLKLRGDAGELKDVDLPPIAGQLGEWGTLTRTLAETLEELQGGEGGVYTPRKLLSALVNKLPQFGGGDQHDAHELLRHLLEAVRSEDLRRYQSVILSSLGMNSKVDPAKVDGEVKQKVKFYGQQASDTMLRPEQVFRGFLVSTLECQDCLHQSDRAEYFLDLSLPVAACRPQPPAVARRKTPNENAYNTQEENKPSKHQLKKERIAARKAARKNKGAAGEGGADTSGPAKEDGNSSSEQSDADVEDNLEEQPRPGPALAHTAANFAVYHMESGYNSEKVISADSIRTSPVHLDKEKADNTPERTDKDGPPVAIPLQYEPLENLSNPDSGVASPEATKHNSTETVHDEPSPVKPEYERPASRISFAPEYTNELVSRGISVQGCRNLLENSVDNSYDSLLETKTLNELNEQLDNLYLEEPPPPAPQPRPAPPSPRYVCDEDECSVHSCLAQFTALELLTGNNKVGCELCTERVNGKGGKTIYTNATKRFLVSSPPAVLILHLKRFQIGPRCMFRKMSKHVDFPTVLDLAPFCAMDKVRGQASLLYALPDSDLSGYESGEAAAAEPPAGRWYYVSDSMVSEVSEDKVLRAQAYLLFYERIL

Catalytic Activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Similarity

Belongs to the peptidase C19 family.

Uniprot

H9JCY9 A0A212FL57 A0A2A4JXW8 A0A2W1BDP9 A0A194QBZ4 A0A194RAG9 + More
A0A0L7KZ92 A0A1W4X6H9 D6WXD4 A0A1Y1JVH1 A0A034W4T9 A0A0K8VV12 A0A0T6B0K4 A0A0L0C0D8 U5EYX0 A0A088A035

EC Number

3.4.19.12

Pubmed

19121390 22118469 28756777 26354079 26227816 18362917 + More
19820115 28004739 25348373 26108605

EMBL

BABH01027564 BABH01027565 BABH01027566 BABH01027567 BABH01027568 BABH01027569 + More
BABH01027570 BABH01027571 AGBW02007869 OWR54466.1 NWSH01000402 PCG76659.1 KZ150240 PZC71914.1 KQ459232 KPJ02510.1 KQ460685 KPJ12856.1 JTDY01004200 KOB68465.1 KQ971361 EFA07998.2 GEZM01101955 JAV52168.1 GAKP01009807 JAC49145.1 GDHF01009914 GDHF01000349 JAI42400.1 JAI51965.1 LJIG01016336 KRT80908.1 JRES01001167 KNC24899.1 GANO01000009 JAB59862.1

Proteomes

UP000005204 UP000007151 UP000218220 UP000053268 UP000053240 UP000037510 + More
UP000192223 UP000007266 UP000037069 UP000005203

PRIDE

H9JCY9

Pfam

PF00443 UCH + More
PF02148 zf-UBP

Interpro

IPR038765   Papain-like_cys_pep_sf        + More
IPR018200   USP_CS
IPR001394   Peptidase_C19_UCH
IPR001607   Znf_UBP
IPR013083   Znf_RING/FYVE/PHD
IPR028889   USP_dom

SUPFAM

SSF54001 SSF54001

Gene 3D

3.30.40.10

ProteinModelPortal

H9JCY9 A0A212FL57 A0A2A4JXW8 A0A2W1BDP9 A0A194QBZ4 A0A194RAG9 + More
A0A0L7KZ92 A0A1W4X6H9 D6WXD4 A0A1Y1JVH1 A0A034W4T9 A0A0K8VV12 A0A0T6B0K4 A0A0L0C0D8 U5EYX0 A0A088A035

PDB

2I50 E-value=2.30599e-16, Score=212

KEGG

101745949 K11844 ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12] | (RefSeq) ubiquitin carboxyl-term

GO

GO:0008270 GO:0006511 GO:0016579 GO:0036459 GO:0004197 GO:0004843 GO:0004888 GO:0007016 GO:0005856 GO:0007155 GO:0051015 GO:0003779 GO:0016021

Length:

834

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13854

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00612

outside

1 - 834

Pi

249.916282

Theta

210.051285

Tajima's D

0.766719

CLR

0.02541

CSRT

0.587570621468927

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics