Gene

KWMTBOMO01007

Pre Gene Modal

BGIBMGA001344

Annotation

cyclin_dependent_kinase_4_[Bombyx_mori]

Location

Bomo_Chr2(-):8310843-8314561      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.477 Mitochondrial   Reliability : 1.206 Nuclear   Reliability : 1.123

CDS

ATGATGTCGCGACCGAGTACCTCACAGTCACCACCTGTTGTTGCTTCCATTAACGATGTCAGTGCATTATTTCAAAATGCACAGAAATATGAAGAACTGAGTCTAATTGGTACAGGTGCATATGGGACAGTGTATAAAGCTCGCGATCTTCATAATGGAGGGCAGATTGTAGCTATGAAGAAAGTTAAAGTTGCCCTCACAGAGGATGGGATACCACTCTCAACTGTACGAGAGATTGCCTTGTTAAGACAACTTGAGGCGTATAGACATCCCAATATAGTCAGACTGCTAGATGTCTGCCACGGAGGGCAGTGCTTGGAGCGAGACCAGCAGCTAGTACTATTCCTGGTGTTTGAACATGTGGAACAGGACCTTGACTCTTTCCTTAGTCGAGCACCGGGACCGCTTCCAGAGAGCAGGATTAGAAGCATGTCCCACGATATAATATCAGGGGTGGACTTCTTGCACTCTCATCGCATTGTGCACCGAGATCTCAAACCTCACAATCTCCTGGTGACGGTGGCTGGACGAGTCAAGCTAGCTGACTTTGGTCTCGCCAAGACCTATGATGTAGAGATGAAGCTCACCAGTGTTGTGGTGACGCTGTGGTACCGGCCCCCGGAGGTGCTGCTGGGGGCGCGCTACTGCTCGGCGCTGGACGTGTGGTCGGCGGGCTGCGTGCTGGCGCAGCTGCACACGCGCCGCCCGCTGCTGCCCGGCGCCTCCGACTCCGATCAGCTGCACCGTATCTTTAGATTAATAGGTCGGCCCCCTCGCTCGGAGTGGCCTGACAACGTATCCATAGAGCTGGACAGCTTCCCCAGCTACCCTCCGCAGGACCTGGCCAGAATCCTGCCCAGGATACATCCTCATGCATTAGATCTTATCAAGGGCATGCTGGTGTTTGACCCGTCCAAACGGCTGACGGCGATGGACTGTCTGGAGCACCCTTACTTCACGGAGGAGCCGGTCGCGTAG

Protein

MMSRPSTSQSPPVVASINDVSALFQNAQKYEELSLIGTGAYGTVYKARDLHNGGQIVAMKKVKVALTEDGIPLSTVREIALLRQLEAYRHPNIVRLLDVCHGGQCLERDQQLVLFLVFEHVEQDLDSFLSRAPGPLPESRIRSMSHDIISGVDFLHSHRIVHRDLKPHNLLVTVAGRVKLADFGLAKTYDVEMKLTSVVVTLWYRPPEVLLGARYCSALDVWSAGCVLAQLHTRRPLLPGASDSDQLHRIFRLIGRPPRSEWPDNVSIELDSFPSYPPQDLARILPRIHPHALDLIKGMLVFDPSKRLTAMDCLEHPYFTEEPVA

Similarity

Belongs to the protein kinase superfamily.

Uniprot

D2IGZ3   A0A2W1BE77   A0A194PTM9   A0A2H1W6R1   A0A212F2E3   A0A0N1IPK0   + More
A0A212FE42   A0A2A4IZ57   H9IVR3   Q17L94   A0A182H2N0   B0X906   A0A1Q3FAZ0   U5EVA6   A0A0L7R6K4   A0A182FDW0   A0A084WDE3   A0A182QP23   A0A182NJH3   A0A2M4BTZ2   A0A182JK13   A0A182V4Z2   A0A182TRF8   A0A182XMG3   A0A182KQ23   Q7Q6I9   A0A182KDC4   A0A182I293   W5JMI6   A0A182S9Z4   A0A182R469   A0A182MCA2   A0A2R7WCP1   A0A182YJA6   I6LL49   A0A1W4WV22   T1KLU5   J3JXF4   A0A088AA26   A0A023F4F7   E1ZW69   A0A336K1P0   A0A224XG28   A0A291S6U9   A0A0C9R6W6   A0A1Y1L7U6   A0A0P5XSQ2   A0A026WDZ8   A0A0P5NF85   A0A3L8E4E0   A0A2S2N6M6   A0A0N0BKF9   A0A0P6H955   E9IQJ8   F4X719   A0A2H8TM23   A0A1B6L8Y6   A0A2A3EHD2   A0A151INF8   A0A3M6U1K1   J9JY47   A0A195F8R9   D6WTL2   E0VBN2   A0A151WS65   S4RCS5   A0A2B4SXB2   A0A0L0BLW6   A0A1I8MXG1   A0A1B6J566   A0A0A1WHN4   A0A1B6H2H0   A0A195DUA0   A0A3B0JGI9   A0A232EUP5   W8BJJ2   A0A0P6B8V4   A0A3B0JLS1   A0A154P6Z5   A0A0P5ST91   A0A0N8CZY7   A0A0T6BCP7   A0A087TPE2   A0A1B6CJI3   A0A1I8PNC1   A0A1D2N3C7   V3ZR16   A0A067R1E1   A0A1W4UYA1   A0A0P5RES4   A0A0K8U1N2   A0A034WGA6   A0A3Q0IND4   A0A2L2YGV4   B4MNU4   B4P5Y5   A0A1B0FMX0   A0A1A9Y2Y4   A0A1B0B069   H3DK77  

Pubmed

28756777    26354079    22118469    19121390    17510324    26483478    + More
24438588    20966253    12364791    14747013    17210077    20920257    23761445    25244985    22516182    25474469    20798317    28992199    28004739    24508170    30249741    21282665    21719571    30382153    18362917    19820115    20566863    26108605    25315136    25830018    28648823    24495485    27289101    23254933    24845553    25348373    26561354    17994087    17550304    15496914   

EMBL

GQ250575    ACT83400.1    KZ150216    PZC72135.1    KQ459593    KPI96672.1    + More
ODYU01006684    SOQ48748.1    AGBW02010749    OWR47918.1    KQ460296    KPJ16290.1    AGBW02008983    OWR51978.1    NWSH01004335    PCG65217.1    BABH01038101    CH477217    EAT47481.1    JXUM01023842    KQ560673    KXJ81334.1    DS232513    EDS42912.1    GFDL01010301    JAV24744.1    GANO01001962    JAB57909.1    KQ414646    KOC66478.1    ATLV01022998    KE525339    KFB48237.1    AXCN02000446    GGFJ01007409    MBW56550.1    AAAB01008960    EAA10812.3    APCN01000131    ADMH02001139    ETN63964.1    AXCM01007830    KK854464    PTY16065.1    FJ966898    ADI52631.1    CAEY01000212    BT127923    AEE62885.1    GBBI01002808    JAC15904.1    GL434776    EFN74578.1    UFQS01000063    UFQT01000063    SSW98874.1    SSX19260.1    GFTR01004990    JAW11436.1    MF432983    ATL75334.1    GBYB01003695    JAG73462.1    GEZM01068144    JAV67147.1    GDIP01080091    JAM23624.1    KK107260    EZA54138.1    GDIQ01142930    JAL08796.1    QOIP01000001    RLU27343.1    GGMR01000245    MBY12864.1    KQ435700    KOX80538.1    GDIQ01022663    JAN72074.1    GL764834    EFZ17141.1    GL888828    EGI57781.1    GFXV01002907    MBW14712.1    GEBQ01027935    GEBQ01019817    JAT12042.1    JAT20160.1    KZ288249    PBC31118.1    KQ976933    KYN07010.1    RCHS01002410    RMX47575.1    ABLF02039607    KQ981744    KYN36444.1    KQ971354    EFA05832.1    DS235033    EEB10788.1    KQ982776    KYQ50749.1    LSMT01000008    PFX33819.1    JRES01001669    KNC21017.1    GECU01013399    JAS94307.1    GBXI01016262    GBXI01015985    GBXI01013775    GBXI01009918    GBXI01007336    JAC98029.1    JAC98306.1    JAD00517.1    JAD04374.1    JAD06956.1    GECZ01000904    JAS68865.1    KQ980341    KYN16431.1    OUUW01000001    SPP74470.1    NNAY01002107    OXU22064.1    GAMC01009377    JAB97178.1    GDIP01020219    JAM83496.1    SPP74469.1    KQ434822    KZC07114.1    GDIP01140953    JAL62761.1    GDIP01082351    JAM21364.1    LJIG01001840    KRT85100.1    KK116158    KFM66981.1    GEDC01023813    GEDC01017389    JAS13485.1    JAS19909.1    LJIJ01000255    ODM99786.1    KB202990    ESO86807.1    KK853098    KDR11403.1    GDIQ01101642    JAL50084.1    GDHF01031655    GDHF01021009    GDHF01007615    JAI20659.1    JAI31305.1    JAI44699.1    GAKP01005254    GAKP01005253    JAC53699.1    IAAA01025282    LAA07348.1    CH963848    EDW73783.2    CM000158    EDW91901.1    KRK00197.1    KRK00198.1    CCAG010017066    JXJN01006585    JXJN01006586   

Proteomes

UP000053268    UP000007151    UP000053240    UP000218220    UP000005204    UP000008820    + More
UP000069940    UP000249989    UP000002320    UP000053825    UP000069272    UP000030765    UP000075886    UP000075884    UP000075880    UP000075903    UP000075902    UP000076407    UP000075882    UP000007062    UP000075881    UP000075840    UP000000673    UP000075901    UP000075900    UP000075883    UP000076408    UP000192223    UP000015104    UP000005203    UP000000311    UP000053097    UP000279307    UP000053105    UP000007755    UP000242457    UP000078542    UP000275408    UP000007819    UP000078541    UP000007266    UP000009046    UP000075809    UP000245300    UP000225706    UP000037069    UP000095301    UP000078492    UP000268350    UP000215335    UP000076502    UP000054359    UP000095300    UP000094527    UP000030746    UP000027135    UP000192221    UP000079169    UP000007798    UP000002282    UP000092444    UP000092443    UP000092460    UP000007303   

PRIDE

D2IGZ3    H9IVR3   

Pfam

PF00069   Pkinase        + More
PF01230   HIT

Interpro

IPR000719   Prot_kinase_dom        + More
IPR011009   Kinase-like_dom_sf       
IPR008271   Ser/Thr_kinase_AS       
IPR017441   Protein_kinase_ATP_BS       
IPR036265   HIT-like_sf       
IPR019808   Histidine_triad_CS       
IPR011146   HIT-like       
IPR001310   Histidine_triad_HIT       
IPR028788   CDK6       

SUPFAM

SSF56112   SSF56112        + More
SSF54197   SSF54197       

Gene 3D

3.30.428.10    

CDD

cd07862  STKc_CDK6

ProteinModelPortal

D2IGZ3   A0A2W1BE77   A0A194PTM9   A0A2H1W6R1   A0A212F2E3   A0A0N1IPK0   + More
A0A212FE42   A0A2A4IZ57   H9IVR3   Q17L94   A0A182H2N0   B0X906   A0A1Q3FAZ0   U5EVA6   A0A0L7R6K4   A0A182FDW0   A0A084WDE3   A0A182QP23   A0A182NJH3   A0A2M4BTZ2   A0A182JK13   A0A182V4Z2   A0A182TRF8   A0A182XMG3   A0A182KQ23   Q7Q6I9   A0A182KDC4   A0A182I293   W5JMI6   A0A182S9Z4   A0A182R469   A0A182MCA2   A0A2R7WCP1   A0A182YJA6   I6LL49   A0A1W4WV22   T1KLU5   J3JXF4   A0A088AA26   A0A023F4F7   E1ZW69   A0A336K1P0   A0A224XG28   A0A291S6U9   A0A0C9R6W6   A0A1Y1L7U6   A0A0P5XSQ2   A0A026WDZ8   A0A0P5NF85   A0A3L8E4E0   A0A2S2N6M6   A0A0N0BKF9   A0A0P6H955   E9IQJ8   F4X719   A0A2H8TM23   A0A1B6L8Y6   A0A2A3EHD2   A0A151INF8   A0A3M6U1K1   J9JY47   A0A195F8R9   D6WTL2   E0VBN2   A0A151WS65   S4RCS5   A0A2B4SXB2   A0A0L0BLW6   A0A1I8MXG1   A0A1B6J566   A0A0A1WHN4   A0A1B6H2H0   A0A195DUA0   A0A3B0JGI9   A0A232EUP5   W8BJJ2   A0A0P6B8V4   A0A3B0JLS1   A0A154P6Z5   A0A0P5ST91   A0A0N8CZY7   A0A0T6BCP7   A0A087TPE2   A0A1B6CJI3   A0A1I8PNC1   A0A1D2N3C7   V3ZR16   A0A067R1E1   A0A1W4UYA1   A0A0P5RES4   A0A0K8U1N2   A0A034WGA6   A0A3Q0IND4   A0A2L2YGV4   B4MNU4   B4P5Y5   A0A1B0FMX0   A0A1A9Y2Y4   A0A1B0B069   H3DK77  

PDB

2F2C     E-value=5.27356e-85,     Score=800

KEGG

100316860    K02089 cyclin-dependent kinase 4 [EC:2.7.11.22] | (RefSeq) cyclin dependent kinase 4

PATHWAY

04933    AGE-RAGE signaling pathway in diabetic complications - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0004674   GO:0051301   GO:0004693   GO:0005634   GO:0006468   GO:0004672   GO:0016021   GO:0008353   GO:0043697   GO:0042127   GO:0005925   GO:0007016   GO:0005856   GO:0007155   GO:0051015   GO:0003779  

Length:

325

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00589

Exp number, first 60 AAs:

0.00067

Total prob of N-in:

0.02604

outside

1  -  325

 

 

Pi

285.9033

Theta

146.199396

Tajima's D

2.819769

CLR

0.092872

CSRT

0.969551522423879

Interpretation

Uncertain