Gene

KWMTBOMO00974  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001363

Annotation

40S_ribosomal_protein_S21_[Bombyx_mori]

Location

Bomo_Chr2(+):7694888-7697085      View in EpiBrowser

Full name

40S ribosomal protein S21      

Alternative Name

Overgrown hematopoietic organs at 23B

Location in the cell

Cytoplasmic   Reliability : 1.236 Nuclear   Reliability : 1.465

CDS

ATGCAGAACGACGCCGGTGAATTCGTTGACTTGTACTGCCCGAGGAAATGCTCGGCCAGCAACCGCCTCATCCACGCTAAGGACCATGCTTCAGTACAGCTAGTGATTGCTGACGTAGACCCCGCCACAGGTCGTGCTGCTGACACATCTAAAATGTATGTTGTCTGTGGGGCTATCCGAAGGATGGGAGAGTCTGATGATTGCATCGTGAGGTTAACAAAGAAAGATGGTATACTGGCTAAAAACTATTAA

Protein

MQNDAGEFVDLYCPRKCSASNRLIHAKDHASVQLVIADVDPATGRAADTSKMYVVCGAIRRMGESDDCIVRLTKKDGILAKNY

Description

May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva.
May be an associated component of the ribosome rather than a core structural subunit. May act as a translation initiation factor. Has a role in regulation of cell proliferation in the hematopoietic organs and the imaginal disks of larva (By similarity).

Subunit

Component of the 40S small ribosomal subunit.
Interacts with sta.
Component of the 40S small ribosomal subunit. Interacts with sta.
Component of the 40S small ribosomal subunit (PubMed:23636399). Interacts with sta (PubMed:10022917).

Similarity

Belongs to the eukaryotic ribosomal protein eS21 family.

Keywords

Cytoplasm   Endoplasmic reticulum   Ribonucleoprotein   Ribosomal protein   Complete proteome   Reference proteome   Developmental protein   rRNA processing   Translation regulation   3D-structure   Alternative splicing  

Feature

chain  40S ribosomal protein S21
splice variant  In isoform E.

Uniprot

A0A2H1WF70   E3UUW1   Q962Q8   Q6PUF8   E7DZ14   A0A2W1BEW5   + More
A0A2A4JFE5   I4DMI1   I4DJG0   G0ZED3   Q6F477   A0A3G1T180   S4NGR2   H9IVT2   D1LYP1   A0A194RJ44   A0A194PSF2   A0A212EX61   D6X125   K7IVP3   Q4GXP2   A0A067QSU9   A0A1B6LLV5   A0A182PZ17   A0A182VLH2   A0A182LR90   A0A182XUT2   Q7PTN4   A0A182IIQ4   I3VPF5   A0A224Y4L7   A0A0V0G643   A0A023F9B6   A0A069DNS2   A0A182KJ82   A0A170XEM8   A0A182MX77   A0A182S4T3   A0A182Q8F1   A0A182YFY0   D1M7Z5   Q4GXP3   A0A182IMC5   A0A0P4W0R6   G1K0C6   R4WIC3   Q1HR25   Q4GXP0   A0A2M3YXX0   A0A2M3ZZH4   W5J4B1   A0A182VUS5   A0A182G0G6   A0A1B6M324   A0A1W4XUA8   A0A182NZB0   E0V8X6   A0A195F9A6   A0A0J7KG87   E2AD71   A0A026WUS2   A0A1B0GNG0   A0A0K8TR17   A0A195BYB9   A0A158NCG9   A0A151WMV0   T1DFX5   A0A1L8DRC3   A0A1Q3FAG6   B0W289   B7U4Q0   A0A0J9QUL1   B4Q8M1   A0A0A9XE49   M9PEA6   Q6XIR2   B4I2S0   O76927   B3NA78   Q0PXU5   N6SSV0   A0A182G4B2   A0A182G906   A0A1W4V5V1   A0A3B0KFJ0   B4N002   Q29KF5   B4GSC0   B3MLA8   Q4GXP1   A0A087TQZ7   A0A154PNN6   A0A2A3ER39   A0A088AVR2   A0A1D1Y0G8   A0A336N004   A0A0L7RJA1   A0A1I8N5Z7   A0A1I8P8F4   A0A1L8EHI9  

Pubmed

14668217    28756777    22651552    23622113    19121390    26354079    + More
22118469    18362917    19820115    20075255    24845553    20966253    12364791    14747013    17210077    23049752    25474469    26334808    25244985    27129103    21736942    23691247    17204158    17510324    20920257    23761445    20566863    20798317    24508170    30249741    26369729    21347285    24330624    22936249    17994087    25401762    26823975    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    14525923    10022917    23636399    23537049    26483478    15632085    25315136   

EMBL

ODYU01008272    SOQ51713.1    HM590401    ADP21470.1    AF400218    AY578154    + More
AY769337    HQ424717    ADT80661.1    KZ150094    PZC73652.1    NWSH01001795    PCG70122.1    AK402499    BAM19121.1    AK401428    BAM18050.1    JF265011    AEL28842.1    AB180413    MG846887    AXY94739.1    GAIX01014634    JAA77926.1    BABH01038047    GU084315    ACY95348.1    KQ460152    KPJ17360.1    KQ459593    KPI96366.1    AGBW02011823    OWR46092.1    KQ971367    EFA09390.1    AM048981    KK853059    KDR11921.1    GEBQ01015339    JAT24638.1    AAAB01008797    EAA03627.5    APCN01004115    JW050237    AFK82394.1    GFTR01000965    JAW15461.1    GECL01003351    JAP02773.1    GBBI01000620    JAC18092.1    GBGD01003652    JAC85237.1    GEMB01004497    JAR98783.1    AXCM01004322    AXCN02000850    GU120419    ACY71269.1    AM048980    GDKW01001304    JAI55291.1    ACPB03016329    JO495008    GAHY01001260    AEL79237.1    JAA76250.1    AK417135    BAN20350.1    DQ440269    CH477306    CH477195    ABF18302.1    EAT44098.1    EAT48397.1    AM048983    CAJ17217.1    GGFM01000337    MBW21088.1    GGFK01000551    MBW33872.1    ADMH02002093    ETN59277.1    GEBQ01009654    JAT30323.1    DS234986    EEB09832.1    KQ981727    KYN37023.1    LBMM01008020    KMQ89216.1    GL438684    EFN68619.1    KK107088    QOIP01000008    EZA59762.1    RLU19824.1    AJVK01029420    GDAI01001248    JAI16355.1    KQ976396    KYM92933.1    ADTU01011884    ADTU01011885    KQ982934    KYQ49186.1    GALA01000397    JAA94455.1    GFDF01005123    JAV08961.1    GFDL01010547    JAV24498.1    DS231825    EDS28153.1    FJ430684    ACJ50598.1    CM002910    KMY87763.1    CM000361    EDX03538.1    GBHO01028229    GDHC01006676    JAG15375.1    JAQ11953.1    AE014134    AGB92507.1    AY231767    AY231999    CM000157    AAR09790.1    EDW87456.1    CH480820    EDW54065.1    AJ009557    BT015189    AAF51191.1    AAT94418.1    CAA08751.1    CH954177    EDV57541.1    DQ673441    ABG82014.1    APGK01058032    KB741285    KB632425    ENN70759.1    ERL95368.1    JXUM01143426    KQ569599    KXJ68578.1    JXUM01048552    KQ561567    KXJ78139.1    OUUW01000006    SPP82398.1    CH963920    EDW77937.1    CH379061    EAL33220.2    CH479189    EDW25667.1    CH902620    EDV30697.1    AM048982    CAJ17216.1    KK116363    KFM67536.1    KQ434998    KZC13337.1    KZ288198    PBC33686.1    GDJX01019793    JAT48143.1    UFQT01000062    UFQT01001716    SSX19202.1    SSX31498.1    KQ414582    KOC70863.1    GFDG01000684    JAV18115.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000007266    + More
UP000002358    UP000027135    UP000075885    UP000075903    UP000075882    UP000076407    UP000007062    UP000075840    UP000075881    UP000075883    UP000075900    UP000075886    UP000076408    UP000075880    UP000015103    UP000008820    UP000000673    UP000075920    UP000069272    UP000192223    UP000075884    UP000009046    UP000078541    UP000036403    UP000000311    UP000053097    UP000279307    UP000092462    UP000078540    UP000005205    UP000075809    UP000002320    UP000000304    UP000000803    UP000002282    UP000001292    UP000008711    UP000079169    UP000019118    UP000030742    UP000069940    UP000249989    UP000192221    UP000268350    UP000007798    UP000001819    UP000008744    UP000007801    UP000054359    UP000076502    UP000242457    UP000005203    UP000053825    UP000095301    UP000095300   

PRIDE

Q6PUF8    H9IVT2    O76927   

Pfam

PF00753   Lactamase_B        + More
PF01249   Ribosomal_S21e

Interpro

IPR036866   RibonucZ/Hydroxyglut_hydro        + More
IPR038579   Ribosomal_S21e_sf       
IPR001931   Ribosomal_S21e       
IPR018279   Ribosomal_S21e_CS       
IPR001279   Metallo-B-lactamas       

SUPFAM

SSF56281   SSF56281       

Gene 3D

3.30.1230.20     3.60.15.10    

ProteinModelPortal

A0A2H1WF70   E3UUW1   Q962Q8   Q6PUF8   E7DZ14   A0A2W1BEW5   + More
A0A2A4JFE5   I4DMI1   I4DJG0   G0ZED3   Q6F477   A0A3G1T180   S4NGR2   H9IVT2   D1LYP1   A0A194RJ44   A0A194PSF2   A0A212EX61   D6X125   K7IVP3   Q4GXP2   A0A067QSU9   A0A1B6LLV5   A0A182PZ17   A0A182VLH2   A0A182LR90   A0A182XUT2   Q7PTN4   A0A182IIQ4   I3VPF5   A0A224Y4L7   A0A0V0G643   A0A023F9B6   A0A069DNS2   A0A182KJ82   A0A170XEM8   A0A182MX77   A0A182S4T3   A0A182Q8F1   A0A182YFY0   D1M7Z5   Q4GXP3   A0A182IMC5   A0A0P4W0R6   G1K0C6   R4WIC3   Q1HR25   Q4GXP0   A0A2M3YXX0   A0A2M3ZZH4   W5J4B1   A0A182VUS5   A0A182G0G6   A0A1B6M324   A0A1W4XUA8   A0A182NZB0   E0V8X6   A0A195F9A6   A0A0J7KG87   E2AD71   A0A026WUS2   A0A1B0GNG0   A0A0K8TR17   A0A195BYB9   A0A158NCG9   A0A151WMV0   T1DFX5   A0A1L8DRC3   A0A1Q3FAG6   B0W289   B7U4Q0   A0A0J9QUL1   B4Q8M1   A0A0A9XE49   M9PEA6   Q6XIR2   B4I2S0   O76927   B3NA78   Q0PXU5   N6SSV0   A0A182G4B2   A0A182G906   A0A1W4V5V1   A0A3B0KFJ0   B4N002   Q29KF5   B4GSC0   B3MLA8   Q4GXP1   A0A087TQZ7   A0A154PNN6   A0A2A3ER39   A0A088AVR2   A0A1D1Y0G8   A0A336N004   A0A0L7RJA1   A0A1I8N5Z7   A0A1I8P8F4   A0A1L8EHI9  

PDB

4V6W     E-value=2.89891e-29,     Score=313

KEGG

692689    K02971 small subunit ribosomal protein S21e | (RefSeq) RpS21; ribosomal protein S21

PATHWAY

03010    Ribosome - Bombyx mori (domestic silkworm)

GO

GO:0003735   GO:0006412   GO:0005840   GO:0005791   GO:0005829   GO:0000447   GO:0022627   GO:0000461   GO:0006417   GO:0048542   GO:0042127   GO:0006364   GO:0043022   GO:0007275   GO:0002181   GO:0022626   GO:0005622   GO:0004812   GO:0006418   GO:0004887   GO:0003707   GO:0016021  

PANTHER

PTHR10442  

Subcellular location

Cytoplasm   Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).   With evidence from 2 publications.
Cytosol   Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).   With evidence from 2 publications.
Rough endoplasmic reticulum   Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).   With evidence from 2 publications.

Length:

83

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00047

Exp number, first 60 AAs:

0.00044

Total prob of N-in:

0.25934

outside

1  -  83

 

 

Pi

292.822246

Theta

186.645428

Tajima's D

1.639801

CLR

0

CSRT

0.817009149542523

Interpretation

Uncertain