Gene

KWMTBOMO00928

Pre Gene Modal

BGIBMGA009645

Annotation

PREDICTED:_zinc_transporter_foi-like_[Bombyx_mori]

Location

Bomo_Chr2(-):6483303-6489356      View in EpiBrowser

Full name

Zinc transporter foi      

Alternative Name

Protein fear-of-intimacy
Protein kastchen

Location in the cell

PlasmaMembrane   Reliability : 1.768

CDS

ATGTCACATCATTTGGTGACAGTTTGCATGTTTTGTCTACTGTGCGCCGCCCACACTTGCGGCTCCCACGTGGACATACAGACAGATGGAGTCTCGGCACACGAACCGAGGCTCGAGACCACGGACCACATGCCCCTCGAATTAGAAGAGAAAAGGAGGCTGGATTCGAGGAACCGCTACCATCAGAAGCTTCAGAAGATCAGACAGAAGGATCGCTTGAAGAGGGACGCGAAGAATGTCGACCCTGAGTTGTATGTAGCCCAGATATTCGGCATGTACGGGGACGCCGCTAGTATGACCATGAACCTGACCGGCTTCAACAAGATGCTTGAAGAGCTAGACCTGCATAAGCTGATCGATGGTGGCCAAACGACCGACAGCACGGCCTACTTCCACGTTCAGACGTCGAAGGATGAAGAAGTTGTCAGCTGCGTTAACAGTTCAGAACTGGTTACAACGGTGAACACGAGGTTAAAGCCCCACGACCATGGCCACGGTCACGAGGATCACACCCACAGCGACCACGACCACGAACTCCTAATATCCAAAGACACGTTGAGGTCAGTCTGTCCAATATTGCTGTACCAGAAACTAGCAAACACGTCGATAGAACGTTCTGGATGCGTCAAAGAAACGAATCTACTGGTTCGCCACCACCGAGACTTGGAAGAGAAGGAGAACGCGTACACGAAAAACATGTTCGCGGTCTGGCTGTATTCATCCCTGAGCATAACCGCGATCAGCGCCTGTGGTCTCCTAGGCGTGGCGGTCATCCCTGTCATGCACAAGACTTATTATAACCATCTGCTGCAGTTTCTGGTGGCTCTGGCCGTAGGGACGCTGTGCGGGGACGCCTTGCTGCACCTGATGCCTCACGCGATGAGTCCCATGCACGACCACGAGGGCGGTGGACATGCGGTGGCGGAAATGTCGCACGACGACGGAATGTGGAAGGGATTCGCCGCCATGCTGGGCGTTGTGTTCTTCTATTTCACAGAGAAGGGATTAACGGTTGTCGTTGAGTGGAGGAAACGCAGGCAGAAGTTGGAGGAAGACAAACTTCCGACCAGAGTGCGCGTCCTTAAGGACGAGACGGTCGGGGGATGTTCGGGTGGTTCAAAAGCTCCCATAACGAACACAACTTCGAACAGTCTCATGAAGATCTTTAAGCGGGACGAAAAGGGAGATCCCACAACGAAAACTTGCAAGCACAAATACTCTGAATATCCTTATTGTTATGATGAAATCGATACGGATACTCACGACGAGCACCATCTGAGGGACGGTATACCGCCCAGCCCTAAAGCGAAGCACAACTCCGTAAGCGTGGTCTCGTCCAACGCCCTCAATCCTGAGGGCAAAGAGGAACCCACAGCCAAGGACTGGCTGCTGAAAGCCGAGACCACTCCTGCTGTTGTCGAAATGAACAATATCAAACACAAAGAAGACGGGTCCAAGGATCTGAAGGATGGCGGCAGTTACACAGTTATATTGAGGGAACATTCTAGAGCGCACCACGGTCACTCCCATGCCCATGGGCACGTGCACGCTCCACCGTCGTCGATAGCGTCCGTGGCCTGGATGGTGATCATGGGTGACGGCCTCCACAATTTCACAGACGGCATGGCCATTGGCGCAGCGTTCGCATCCAGCATAGCAGGTGGATTCTCGACCGCCATCGCGGTGCTCTGCCATGAACTTCCTCACGAGCTGGGCGATTTCGCGGTGTTACTGAAGGCGGGCATGTCTGTTAAGCGTGCTGTCTGCTACAACATACTGTCGTCGGCTCTGTGCTTGGCGGGGATGGTCTGCGGGGTCCTGGCCGGGCACGCCCCCTCGGCAACCAGGTGGCTATTCGCAGTGGCAGCTGGCATGTTCCTCTACATAGCCCTCGTTGATATGATGCCTGAACTTAGCACGTCTCACAGCAACGAGGGTACGCTATGCCAATGTGTGCTGCAACTGATGGGTCTAGCCAGCGGCATCGGTATAATGCTGGTCATCGCTCTATACGAAGACGACCTCAAAAACCTGTTCGGCTGA

Protein

MSHHLVTVCMFCLLCAAHTCGSHVDIQTDGVSAHEPRLETTDHMPLELEEKRRLDSRNRYHQKLQKIRQKDRLKRDAKNVDPELYVAQIFGMYGDAASMTMNLTGFNKMLEELDLHKLIDGGQTTDSTAYFHVQTSKDEEVVSCVNSSELVTTVNTRLKPHDHGHGHEDHTHSDHDHELLISKDTLRSVCPILLYQKLANTSIERSGCVKETNLLVRHHRDLEEKENAYTKNMFAVWLYSSLSITAISACGLLGVAVIPVMHKTYYNHLLQFLVALAVGTLCGDALLHLMPHAMSPMHDHEGGGHAVAEMSHDDGMWKGFAAMLGVVFFYFTEKGLTVVVEWRKRRQKLEEDKLPTRVRVLKDETVGGCSGGSKAPITNTTSNSLMKIFKRDEKGDPTTKTCKHKYSEYPYCYDEIDTDTHDEHHLRDGIPPSPKAKHNSVSVVSSNALNPEGKEEPTAKDWLLKAETTPAVVEMNNIKHKEDGSKDLKDGGSYTVILREHSRAHHGHSHAHGHVHAPPSSIASVAWMVIMGDGLHNFTDGMAIGAAFASSIAGGFSTAIAVLCHELPHELGDFAVLLKAGMSVKRAVCYNILSSALCLAGMVCGVLAGHAPSATRWLFAVAAGMFLYIALVDMMPELSTSHSNEGTLCQCVLQLMGLASGIGIMLVIALYEDDLKNLFG

Description

Required for the normal migration of longitudinal and peripheral glial cells. During larval development, required for the migration of the subretinal glia into the eye disk. During embryonic development, also controls the migration of muscle cells toward their attachment sites. Required in the mesoderm for the correct morphogenesis of embryonic gonad and for tracheal branch fusion during tracheal development. Shg may be cooperating with foi to mediate a common mechanism for gonad and tracheal morphogenesis. Acts as a zinc transporter in both yeast and mammalian cells.

Similarity

Belongs to the ZIP transporter (TC 2.A.5) family.

Keywords

Cell membrane   Complete proteome   Developmental protein   Differentiation   Glycoprotein   Ion transport   Membrane   Neurogenesis   Phosphoprotein   Reference proteome   Signal   Transmembrane   Transmembrane helix   Transport   Zinc   Zinc transport  

Feature

chain  Zinc transporter foi

Uniprot

A0A2H1V9Z0   A0A212FBM1   A0A0N0PD99   A0A194PT92   A0A2A4J0W5   A0A0L7LFI5   + More
A0A1B0CGU2   A0A1L8DDX3   A0A1L8DE56   A0A1L8DDW2   A0A1L8DDY9   E2B260   A0A0C9R9D7   A0A195C9I3   A0A151I5J1   A0A1B6GI83   A0A1B6KB35   A0A0M8ZNQ0   A0A2A3EMP4   A0A088AC68   A0A151WNG3   A0A232EWT8   A0A158NU01   A0A0L7RET1   F4WXB0   A0A026X0W0   A0A336LX90   A0A195DJG1   A0A1B6F1U2   A0A3L8DST0   A0A1B6DE89   A0A1J1JA36   A0A182M706   A0A1W4XTK0   A0A154P2S3   A0A2J7QRD8   A0A2J7QRD0   A0A1Y1KCT6   A0A2J7QRE2   A0A2J7QRF0   A0A224XI10   A0A1Q3FVT7   A0A1Q3FVM2   A0A310STU8   A0A0P4VRX1   Q16RN0   A0A182QQ70   A0A139WEH4   A0A182WCK3   A0A182RDF0   A0A084VDG5   A0A182S8G6   A0A182K0Z9   A0A182PJW2   B4PG09   A0A0A9XM25   B4N5A7   Q29R33   M9PES6   Q9VSL7  

Pubmed

22118469    26354079    26227816    20798317    28648823    21347285    + More
21719571    24508170    30249741    28004739    27129103    17510324    18362917    19820115    24438588    17994087    17550304    25401762    26823975    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12702650    15464587    15509557    18327897   

EMBL

ODYU01001445    SOQ37655.1    AGBW02009306    OWR51113.1    KQ460280    KPJ16311.1    + More
KQ459593    KPI96636.1    NWSH01003798    PCG65807.1    JTDY01001278    KOB74313.1    AJWK01011588    AJWK01011589    AJWK01011590    AJWK01011591    GFDF01009428    JAV04656.1    GFDF01009427    JAV04657.1    GFDF01009425    JAV04659.1    GFDF01009426    JAV04658.1    GL445059    EFN60235.1    GBYB01013018    GBYB01013019    JAG82785.1    JAG82786.1    KQ978143    KYM96773.1    KQ976445    KYM86078.1    GECZ01007617    JAS62152.1    GEBQ01031318    GEBQ01029085    GEBQ01028066    GEBQ01007362    JAT08659.1    JAT10892.1    JAT11911.1    JAT32615.1    KQ435970    KOX67797.1    KZ288210    PBC32960.1    KQ982926    KYQ49225.1    NNAY01001826    OXU22795.1    ADTU01026230    KQ414608    KOC69467.1    GL888423    EGI61159.1    KK107046    EZA61713.1    UFQT01000031    SSX18258.1    KQ980794    KYN13035.1    GECZ01025631    JAS44138.1    QOIP01000004    RLU23386.1    GEDC01013280    JAS24018.1    CVRI01000075    CRL08732.1    AXCM01001750    KQ434796    KZC05644.1    NEVH01011907    PNF31148.1    PNF31149.1    GEZM01086504    JAV59279.1    PNF31146.1    PNF31147.1    GFTR01006978    JAW09448.1    GFDL01003387    JAV31658.1    GFDL01003391    JAV31654.1    KQ760512    OAD60051.1    GDKW01002775    JAI53820.1    CH477702    EAT37058.1    AXCN02000347    KQ971354    KYB26289.1    ATLV01011335    KE524664    KFB36009.1    CM000159    EDW93153.1    KRK00986.1    GBHO01023731    GBHO01023730    GBRD01014230    GDHC01016407    JAG19873.1    JAG19874.1    JAG51596.1    JAQ02222.1    CH964101    EDW79546.1    BT024207    ABC86269.1    AE014296    AGB94279.1    AGB94280.1    AHN58010.1    AAF50401.3   

Proteomes

UP000007151    UP000053240    UP000053268    UP000218220    UP000037510    UP000092461    + More
UP000000311    UP000078542    UP000078540    UP000053105    UP000242457    UP000005203    UP000075809    UP000215335    UP000005205    UP000053825    UP000007755    UP000053097    UP000078492    UP000279307    UP000183832    UP000075883    UP000192223    UP000076502    UP000235965    UP000008820    UP000075886    UP000007266    UP000075920    UP000075900    UP000030765    UP000075901    UP000075881    UP000075885    UP000002282    UP000007798    UP000000803   

PRIDE

Q29R33    M9PES6    Q9VSL7   

Pfam

PF02535   Zip        + More
PF03388   Lectin_leg-like

Interpro

IPR003689   ZIP        + More
IPR002048   EF_hand_dom       
IPR005052   Lectin_leg       
IPR013320   ConA-like_dom_sf       

SUPFAM

SSF49899   SSF49899       

ProteinModelPortal

A0A2H1V9Z0   A0A212FBM1   A0A0N0PD99   A0A194PT92   A0A2A4J0W5   A0A0L7LFI5   + More
A0A1B0CGU2   A0A1L8DDX3   A0A1L8DE56   A0A1L8DDW2   A0A1L8DDY9   E2B260   A0A0C9R9D7   A0A195C9I3   A0A151I5J1   A0A1B6GI83   A0A1B6KB35   A0A0M8ZNQ0   A0A2A3EMP4   A0A088AC68   A0A151WNG3   A0A232EWT8   A0A158NU01   A0A0L7RET1   F4WXB0   A0A026X0W0   A0A336LX90   A0A195DJG1   A0A1B6F1U2   A0A3L8DST0   A0A1B6DE89   A0A1J1JA36   A0A182M706   A0A1W4XTK0   A0A154P2S3   A0A2J7QRD8   A0A2J7QRD0   A0A1Y1KCT6   A0A2J7QRE2   A0A2J7QRF0   A0A224XI10   A0A1Q3FVT7   A0A1Q3FVM2   A0A310STU8   A0A0P4VRX1   Q16RN0   A0A182QQ70   A0A139WEH4   A0A182WCK3   A0A182RDF0   A0A084VDG5   A0A182S8G6   A0A182K0Z9   A0A182PJW2   B4PG09   A0A0A9XM25   B4N5A7   Q29R33   M9PES6   Q9VSL7  

KEGG

101738511    K14716 solute carrier family 39 (zinc transporter), member 10 | (RefSeq) zinc transporter foi-like

GO

GO:0046873   GO:0016021   GO:0005509   GO:0006882   GO:0005385   GO:0071578   GO:0005887   GO:0005537   GO:0005737   GO:0006888   GO:0007506   GO:0035262   GO:0009986   GO:0007417   GO:0008354   GO:0016323   GO:0035147   GO:0030154   GO:0005886   GO:0006829   GO:0007280   GO:0016477   GO:0008406   GO:0016020   GO:0030001   GO:0006422   GO:0004812   GO:0006418   GO:0004887   GO:0003707   GO:0055085  

Subcellular location

Cell membrane  

SignalP

Position:   1 - 21,         Likelihood:  0.987042

 

 

Length:

680

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

151.69237

Exp number, first 60 AAs:

0.29013

Total prob of N-in:

0.07273

outside

1  -  235

TMhelix

236  -  258

inside

259  -  264

TMhelix

265  -  287

outside

288  -  319

TMhelix

320  -  342

inside

343  -  586

TMhelix

587  -  609

outside

610  -  612

TMhelix

613  -  632

inside

633  -  651

TMhelix

652  -  671

outside

672  -  680

 

 

Pi

209.145984

Theta

203.05214

Tajima's D

0.216032

CLR

0.526011

CSRT

0.430678466076696

Interpretation

Uncertain