Gene

KWMTBOMO00922

Pre Gene Modal

BGIBMGA009791

Annotation

carotenoid-binding_protein_isoform_1_[Bombyx_mori]

Location

Bomo_Chr2(+):6366737-6405071      View in EpiBrowser

Full name

Steroidogenic acute regulatory protein-like      

Location in the cell

PlasmaMembrane   Reliability : 3.266

CDS

ATGTCTCATCCTCACATACGAGAAGCAGCTGAATCTCTCTTAAACAGCGTCACGTCCCCGCCTTATAGAATGATGAATCATTCACAGTCCGTGAATCTGATGACCGAGGACCTAGTGGCGGGACACAGGCCCGCCGGGAAGATGTCCTCGGTCAGAAGGTTCTTCTGTCTCTTCGTGACCTTCGATTTAATGTTCACAAGCCTCATGTGGCTGATTTGTGTTATGGTTCGTAACGAGACGTTAGACCAAATATTGCAAAGAGAAATTATTAGTTATAATATAAAACTATCGTTATTCGACATAGTGGTGTTAGCTGTGATAAGATTTACAATATTATTGTTGTTCTACGCTTTATTATATATCAACAATTGGAGTGTGATAGCTCTCTCGACAAGCGGCACTTGCGCCTTTTTAATAGCGAAAGTGTTCGTATTCGTTTGGTCCGATGCGTCACAGCCCGTGTATCAAGTGTTCCTTATACTGACTTCGTTTACCTTGTCATGGGGAGAGGCCTGGTTCTTGGACTTCAGGGTCTTACCGCAGGAGCTACACTGCAAGGAGATACTAGATTCCTTAGCTCAGCACAGCGTCTCCGAGCGCACGCCGCTACTGGACCCTCAGCCCGGTGTGAATTCGACGTACGCAGAGTCCACGGTTAAATGGTTCTCCCCGGTCGACACGCCGGAGTCGAGTCCACGGCCGCGCAGGTTCGGGGAGCAAGTCATATTGACGCAGGAGCAGATCGATGAGTACAAGAGTCAGGCTAACGAGAGCATGGCGAACGCTTGGCGCATCATCACGCTGCCAAACTGGACGGTGGAGAAGCGAGGGTCCGTCAGGGGAGACGTCGTGGAGTCCAGGAAAGTTGAAGGCTACGGCAAGGTCTATAGATTTACGGGCGTCGTCAACTGTCCCGCCAGGTTTCTATACGAGGAGTTCAAGAACAACCTGACGAAGTTGCCCGAATGGAATCCGACGATATTGAAATGCGAAATAATTAAGGAAATCGGCGATGGCGTGGACCTGTCGTACCAGGTGACGGCTGGCGGGGGACGAGGCATAATAACCCCTCGCGACTTCGTGATCCTGCGCCGGATCGCGCTACTCTCCCGGGAGGGACGCGTCGTCGACGACAATCCCCACGGATACATCAGTAGCGGAGTCAGCGTTCAAGTTCCCGGGTACCCGCCCCTCAAGGAGATGGTTAGGGGACACAATAAAGTTGGTTGCTGGTACCTACAGCCTCGGACTGTACAAACTGCTGGAGGAAAAATCGAGGACCAGACCCTGTTCCAATGGTTGATGTGTTGTGATCTCAAAGGTAAAATACCTCAATTCGTGTTGGACGTCGCTTTCGCCACTGTGATGCTGGACTACATCGTGCACGTCAGGAAGTTCGTGGCCGAAGCGAAGGCCAGAGCCGAATTCTGA

Protein

MSHPHIREAAESLLNSVTSPPYRMMNHSQSVNLMTEDLVAGHRPAGKMSSVRRFFCLFVTFDLMFTSLMWLICVMVRNETLDQILQREIISYNIKLSLFDIVVLAVIRFTILLLFYALLYINNWSVIALSTSGTCAFLIAKVFVFVWSDASQPVYQVFLILTSFTLSWGEAWFLDFRVLPQELHCKEILDSLAQHSVSERTPLLDPQPGVNSTYAESTVKWFSPVDTPESSPRPRRFGEQVILTQEQIDEYKSQANESMANAWRIITLPNWTVEKRGSVRGDVVESRKVEGYGKVYRFTGVVNCPARFLYEEFKNNLTKLPEWNPTILKCEIIKEIGDGVDLSYQVTAGGGRGIITPRDFVILRRIALLSREGRVVDDNPHGYISSGVSVQVPGYPPLKEMVRGHNKVGCWYLQPRTVQTAGGKIEDQTLFQWLMCCDLKGKIPQFVLDVAFATVMLDYIVHVRKFVAEAKARAEF

Description

May bind to and transport cholesterol and may play a role in ecdysteroid biosynthesis.

Keywords

Alternative splicing   Complete proteome   Lipid transport   Lipid-binding   Membrane   Reference proteome   Steroidogenesis   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Steroidogenic acute regulatory protein-like
splice variant  In isoform B.

Uniprot

Q3V5Y6   D6WT76   A0A2J7RRK7   A0A067RND7   A0A2J7RRL2   A0A2J7RRI0   + More
A0A2J7RRJ7   E9FUI1   A0A1Y1N158   A0A1Y1MZS7   A0A0P5V2X9   A0A0P5JA07   A0A0P5LQT0   A0A0P6C0B4   A0A0P5B236   A0A0P5CZM4   A0A0N7ZPD8   A0A0P4YZF7   A0A0P5V270   A0A0P4ZIB0   A0A0P5BKX0   V5GWI2   K7INF7   E2BKV3   A0A154PI58   A0A0N8EK28   E2AXF6   A0A232ENV8   A0A0N8CZL7   A0A0C9RE63   A0A189XGA0   A0A3L8DCB3   A0A026WKG3   A0A0L0CLS7   A0A1L8DY45   A0A1L8DYJ2   B4H561   B5E1A0   A0A3B0J3D2   A0A0K8W3V8   A0A0C9R542   A0A0K8UUC4   A0A034VJP0   A0A0M4EB96   A0A3B0JM71   A0A1A9VWE5   A0A195EET5   A0A195D402   A0A1I8PDW8   A0A2P8XXI2   A0A0L7RBS2   A0A195ESU6   A0A158NTM5   B4MP76   A0A151I2E5   A0A182Q372   A0A087ZMS2   A0A1W4W0I6   A0A182WWT2   A0A182HWG1   A0A1A9WA31   A0A151X343   A0A0P4WBR8   T1PBR4   A0A1I8NFT8   A0A0A1XIE6   B3NQU6   A0A1B0B6G6   B4PBD0   A0A182NJQ0   W8BVC6   A0A182Y264   A0A1Q3G1B7   A0A1B0D5P1   B4QC20   A0A1B0FN74   Q9W145-2   A0A1A9YDA3   B4IH40   Q9W145   B4LJI9   A0A1Q3G164  

Pubmed

16169523    18362917    19820115    24845553    21292972    28004739    + More
20075255    20798317    28648823    30249741    24508170    26108605    17994087    15632085    23185243    25348373    29403074    21347285    25315136    25830018    17550304    24495485    25244985    22936249    14745013    10731132    12537572    18057021   

EMBL

AB211534    AB211535    BAE44461.1    BAE44462.1    KQ971354    EFA07554.1    + More
NEVH01000603    PNF43452.1    KK852521    KDR22110.1    PNF43454.1    PNF43449.1    PNF43453.1    GL732525    EFX88733.1    GEZM01016737    JAV91158.1    GEZM01016736    JAV91159.1    GDIP01105553    JAL98161.1    GDIQ01228002    GDIQ01228001    JAK23723.1    GDIQ01242450    GDIQ01211903    GDIQ01192960    GDIQ01190910    GDIQ01189508    GDIP01134150    GDIQ01072252    LRGB01000868    JAK60815.1    JAL69564.1    KZS15573.1    GDIP01011478    JAM92237.1    GDIP01190930    JAJ32472.1    GDIP01167391    JAJ56011.1    GDIP01225633    JAI97768.1    GDIP01222784    JAJ00618.1    GDIP01108097    JAL95617.1    GDIP01225632    JAI97769.1    GDIP01188338    JAJ35064.1    GALX01002409    JAB66057.1    GL448826    EFN83702.1    KQ434899    KZC10880.1    GDIQ01019044    JAN75693.1    GL443549    EFN61880.1    NNAY01003047    OXU20059.1    GDIP01083311    JAM20404.1    GBYB01011437    GBYB01011438    JAG81204.1    JAG81205.1    KT072711    ALO17561.1    QOIP01000010    RLU17971.1    KK107171    EZA56111.1    JRES01000204    KNC33323.1    GFDF01002748    JAV11336.1    GFDF01002749    JAV11335.1    CH479210    EDW32897.1    CM000071    EDY69488.1    ENO01925.2    OUUW01000001    SPP73742.1    GDHF01027525    GDHF01010397    GDHF01009665    GDHF01008147    GDHF01006426    GDHF01005581    JAI24789.1    JAI41917.1    JAI42649.1    JAI44167.1    JAI45888.1    JAI46733.1    GBYB01011439    JAG81206.1    GDHF01022186    GDHF01017644    JAI30128.1    JAI34670.1    GAKP01016923    GAKP01016922    GAKP01016921    GAKP01016920    JAC42030.1    CP012524    ALC40752.1    SPP73741.1    KQ978983    KYN26748.1    KQ976881    KYN07617.1    PYGN01001214    PSN36624.1    KQ414617    KOC68377.1    KQ981993    KYN30987.1    ADTU01026048    ADTU01026049    CH963848    EDW73915.2    KQ976543    KYM81019.1    AXCN02000497    APCN01001489    KQ982562    KYQ54846.1    GDRN01054278    JAI66101.1    KA645403    AFP60032.1    GBXI01008943    GBXI01003541    JAD05349.1    JAD10751.1    CH954179    EDV57029.1    JXJN01009092    CM000158    EDW92562.1    KRK00579.1    GAMC01013491    JAB93064.1    GFDL01001453    JAV33592.1    AJVK01025461    AJVK01025462    CM000362    CM002911    EDX08575.1    KMY96376.1    CCAG010014920    AY455866    AE013599    AY102683    AAM27512.1    AAR19767.1    CH480838    EDW49216.1    CH940648    EDW61557.1    KRF80062.1    KRF80063.1    GFDL01001513    JAV33532.1   

Proteomes

UP000007266    UP000235965    UP000027135    UP000000305    UP000076858    UP000002358    + More
UP000008237    UP000076502    UP000000311    UP000215335    UP000279307    UP000053097    UP000037069    UP000008744    UP000001819    UP000268350    UP000092553    UP000078200    UP000078492    UP000078542    UP000095300    UP000245037    UP000053825    UP000078541    UP000005205    UP000007798    UP000078540    UP000075886    UP000005203    UP000192221    UP000076407    UP000075840    UP000091820    UP000075809    UP000095301    UP000008711    UP000092460    UP000002282    UP000075884    UP000076408    UP000092462    UP000000304    UP000092444    UP000000803    UP000092443    UP000001292    UP000008792   

PRIDE

Q3V5Y6    Q9W145   

Pfam

PF10457   MENTAL        + More
PF01852   START
PF02770   Acyl-CoA_dh_M
PF00441   Acyl-CoA_dh_1
PF02771   Acyl-CoA_dh_N
PF00160   Pro_isomerase
PF00400   WD40

Interpro

IPR002913   START_lipid-bd_dom        + More
IPR023393   START-like_dom_sf       
IPR019498   MENTAL       
IPR000799   StAR-like       
IPR006089   Acyl-CoA_DH_CS       
IPR013786   AcylCoA_DH/ox_N       
IPR036250   AcylCo_DH-like_C       
IPR037069   AcylCoA_DH/ox_N_sf       
IPR009100   AcylCoA_DH/oxidase_NM_dom       
IPR006091   Acyl-CoA_Oxase/DH_cen-dom       
IPR009075   AcylCo_DH/oxidase_C       
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR017986   WD40_repeat_dom       
IPR002130   Cyclophilin-type_PPIase_dom       
IPR001680   WD40_repeat       
IPR029000   Cyclophilin-like_dom_sf       

SUPFAM

SSF56645   SSF56645        + More
SSF47203   SSF47203       
SSF50978   SSF50978       
SSF50891   SSF50891       

Gene 3D

3.30.530.20     1.10.540.10     2.130.10.10     2.40.100.10    

ProteinModelPortal

Q3V5Y6   D6WT76   A0A2J7RRK7   A0A067RND7   A0A2J7RRL2   A0A2J7RRI0   + More
A0A2J7RRJ7   E9FUI1   A0A1Y1N158   A0A1Y1MZS7   A0A0P5V2X9   A0A0P5JA07   A0A0P5LQT0   A0A0P6C0B4   A0A0P5B236   A0A0P5CZM4   A0A0N7ZPD8   A0A0P4YZF7   A0A0P5V270   A0A0P4ZIB0   A0A0P5BKX0   V5GWI2   K7INF7   E2BKV3   A0A154PI58   A0A0N8EK28   E2AXF6   A0A232ENV8   A0A0N8CZL7   A0A0C9RE63   A0A189XGA0   A0A3L8DCB3   A0A026WKG3   A0A0L0CLS7   A0A1L8DY45   A0A1L8DYJ2   B4H561   B5E1A0   A0A3B0J3D2   A0A0K8W3V8   A0A0C9R542   A0A0K8UUC4   A0A034VJP0   A0A0M4EB96   A0A3B0JM71   A0A1A9VWE5   A0A195EET5   A0A195D402   A0A1I8PDW8   A0A2P8XXI2   A0A0L7RBS2   A0A195ESU6   A0A158NTM5   B4MP76   A0A151I2E5   A0A182Q372   A0A087ZMS2   A0A1W4W0I6   A0A182WWT2   A0A182HWG1   A0A1A9WA31   A0A151X343   A0A0P4WBR8   T1PBR4   A0A1I8NFT8   A0A0A1XIE6   B3NQU6   A0A1B0B6G6   B4PBD0   A0A182NJQ0   W8BVC6   A0A182Y264   A0A1Q3G1B7   A0A1B0D5P1   B4QC20   A0A1B0FN74   Q9W145-2   A0A1A9YDA3   B4IH40   Q9W145   B4LJI9   A0A1Q3G164  

PDB

5I9J     E-value=1.07824e-23,     Score=273

KEGG

692547    K22291 StAR-related lipid transfer protein 3 | (RefSeq) Cbp, Start1; carotenoid-binding protein

GO

GO:0016021   GO:0008289   GO:0050660   GO:0003995   GO:0003755   GO:0006869   GO:0006694   GO:0016758   GO:0003677   GO:0019001   GO:0031683   GO:0007165   GO:0000166   GO:0004887   GO:0003707  

Subcellular location

Membrane  

Length:

476

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

85.15067

Exp number, first 60 AAs:

6.73186

Total prob of N-in:

0.40847

inside

1  -  53

TMhelix

54  -  76

outside

77  -  95

TMhelix

96  -  118

inside

119  -  124

TMhelix

125  -  147

outside

148  -  476

 

 

Pi

272.874736

Theta

174.349428

Tajima's D

3.145123

CLR

0.300752

CSRT

0.987000649967502

Interpretation

Possibly Positive selection