Gene

KWMTBOMO00919

Pre Gene Modal

BGIBMGA009787

Annotation

UDP-glycosyltransferase_UGT33R2_precursor_[Bombyx_mori]

Location

Bomo_Chr2(+):6347807-6352253      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

Mitochondrial   Reliability : 1.015 PlasmaMembrane   Reliability : 1.533

CDS

ATGATCCTGAGGGTGGTCATAGCGTTAGCCTTTTGTGCGCCGCACACGCACACGGCAAGGATTCTTATTATCGTGCCCACACCGGCATACAGCCATCAGCTGATCTTCCGCCCAATAATCGAAGAGCTAACCAAGAACCATCAAGTAACATTTATAACCACGAACCCAGCGTATCCGAAGGGAGATACCCCACGGAACCTCACGGAAATCGACGCGGGTCCGATCTCTTATTCGCTGTGGAACCAGGAAGTTTCAATAACTAAATTCGGGAAAGACAACTTTATTTACGACGGCGTAAATGTTATTTTTGAGGTTATGCCGAAGATATTTGCAGAGCAACTTCGTTTGGCGGATGTTGAGAAATTGATCCGTAATGCCCAATTCGATCTGCTAATTTTAGAAGCTTGGTTTCAACCGATATTGATCTGGTCGTACCTGTACAAAGTTCCAGTGCTGCAGATCAGTTCCATGGGCACTAGTCCCGGCAACCCTGACACCATGGGCCTGCCCGACTATTGGACTTATCACCCTTCGTTATTTCATCAGAAGATCTACGACCTAACGACCTCGGAAAGGATTAGCGAAATGCTTAGATATCTGCACGTGCAATCGGTTTTTGATGCGAACGAGGCCAAAGAGGATGAGATTTTAAAAGGTATTTTCAATGATGCACCTCCTCTTAGGAGTTTAAGGAGGAACGTGGACGCCATGCTCTTGAACTTGAACCCGTTGTGGGACAATAACCGTCCTTTGCCGCAGAACGTTCATTACATCGGGAATATCAATCGTAATCCTGCGAAGGAATTGCCAAGGGATCTCCAAGCGTATTTGGATTCATCTGACACCGGCGTGATCTACATGAGCTTCGGCACAAACGTTCCTCCTTCAAAGCTGCCTCGTCAGCTGACGCAGATGTTCGCGAGCGTATTCCGTGAGCTGCCGTACAAGGTGCTGTGGAAGTGGGACCTCGACGTGGTGGAGGGGATGCCGGAGAACGTCAAGACCGGACGGTGGTTCCCGCAGGCTGATGTCTTCAGACATCCGAACGTGAAGCTGGTGATAACCCAGGCAGGGCTGTAG

Protein

MILRVVIALAFCAPHTHTARILIIVPTPAYSHQLIFRPIIEELTKNHQVTFITTNPAYPKGDTPRNLTEIDAGPISYSLWNQEVSITKFGKDNFIYDGVNVIFEVMPKIFAEQLRLADVEKLIRNAQFDLLILEAWFQPILIWSYLYKVPVLQISSMGTSPGNPDTMGLPDYWTYHPSLFHQKIYDLTTSERISEMLRYLHVQSVFDANEAKEDEILKGIFNDAPPLRSLRRNVDAMLLNLNPLWDNNRPLPQNVHYIGNINRNPAKELPRDLQAYLDSSDTGVIYMSFGTNVPPSKLPRQLTQMFASVFRELPYKVLWKWDLDVVEGMPENVKTGRWFPQADVFRHPNVKLVITQAGL

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.
Belongs to the peptidase S1 family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPT4   G9LPT3   H9JCT0   H9JJT6   M4M1W9   A0A191T1K8   + More
A0A2H1W7S2   A0A024AG00   A0A2H4WB75   A0A024AGF9   G9LPT1   A0A191T1K4   A0A0N0PE43   A0A2W1BL20   A0A191T2F8   A0A2W1BCY8   A0A2W1BEB8   G9LPP3   A0A2A4IVU8   A0A191T1L3   G9LPS9   A0A191T1M4   B7TZA3   G9LPP0   A0A191T2G1   A0A2W1B485   A0A2W1B675   A0A2H1V761   A0A191T1L8   A0A2W1BE55   A0A0N1PE65   G9LPN9   A0A2W1BEA5   A0A2W1B3V4   G9LPN3   G9LPN6   A0A140EA35   G9LPP5   A0A191T2J2   G9LPP2   A0A2W1B8D3   A0A2H4WB73   A0A2W1B475   A0A2H1VU94   G9LPN5   G9LPS6   A0A2W1B7N5   H9JWB6   A0A0N1I2R8   A0A2H1VUM4   A0A1L8D6F0   A0A1L8D6T8   F1DG68   G9LPN2   G9LPP1   Q1HPX7   A0A2W1B9W6   A0A0L7LF59   G9LPS2   A0A2W1B3X2   A0A2W1B6A2   G9LPP4   G9LPT0   A0A2W1BBH1   A0A2W1BHY3   A0A2W1B8G2   A0A2W1BDA5   A0A191T1N0   G9LPS5   A0A024AGL3   G9LPN8   G9LPN4   G9LPS3   A0A2H1WTF5   A0A191T2J5   H9JWE6   H9JWB7   A0A0N1IB27   G9LPS8   A0A2I6RJL8   A0A024AH14   A0A2W1BHP8   G9LPN7   A0A2H1VUS4   A0A2W1BA70   G9LPP7   A0A2W1BQP4   H9JWC2   A0A2A4JWQ0   A0A191T1L2   D2JLK8   A0A2H1WSA7   H9JWB9   A0A0N1ICS6   A0A0N0P9C8   G9LPS4   A0A191T2G3   A0A0N1IB34   A0A0L7LGS1  

EC Number

2.4.1.17

Pubmed

22155036    19121390    24698447    29027758    26354079    28756777    + More
26873292    26227816    19954531    21505429   

EMBL

JQ070241    AEW43157.1    JQ070240    AEW43156.1    BABH01040891    BABH01017785    + More
JQ747500    AGG36457.1    KU680282    ANI21988.1    ODYU01006890    SOQ49139.1    KF777109    AHY99680.1    KY202945    AUC64289.1    KF777110    AHY99681.1    JQ070238    AEW43154.1    KU680283    ANI21989.1    KQ459937    KPJ19195.1    KZ150193    PZC72373.1    KU680280    ANI21986.1    KZ150360    PZC71197.1    PZC71200.1    JQ070200    AEW43116.1    NWSH01005967    PCG63789.1    KU680288    ANI21994.1    BABH01029271    JQ070236    AEW43152.1    KU680286    ANI21992.1    FJ418685    ACJ48963.1    JQ070197    AEW43113.1    KU680285    ANI21991.1    PZC71199.1    KZ150704    PZC70375.1    ODYU01001030    SOQ36683.1    KU680281    ANI21987.1    PZC71196.1    KQ459547    KPJ00045.1    JQ070196    AEW43112.1    PZC71190.1    PZC71192.1    JQ070190    AEW43106.1    JQ070193    AEW43109.1    KU214506    AMK97472.1    JQ070202    AEW43118.1    KU680284    ANI21990.1    JQ070199    AEW43115.1    PZC71191.1    KY202933    AUC64277.1    PZC71189.1    ODYU01004485    SOQ44409.1    JQ070192    AEW43108.1    JQ070233    AEW43149.1    PZC70374.1    KPJ00048.1    ODYU01004546    SOQ44549.1    GEYN01000093    JAV02036.1    GEYN01000079    JAV02050.1    HQ833816    ADY17534.1    JQ070189    AEW43105.1    JQ070198    AEW43114.1    DQ443275    ABF51364.1    PZC72369.1    JTDY01001352    KOB74102.1    JQ070229    AEW43145.1    PZC71202.1    PZC71198.1    JQ070201    AEW43117.1    JQ070237    AEW43153.1    PZC71194.1    PZC72370.1    PZC71201.1    PZC72371.1    KU680291    ANI21997.1    JQ070232    AEW43148.1    KF777112    AHY99683.1    JQ070195    AEW43111.1    JQ070191    AEW43107.1    JQ070230    AEW43146.1    ODYU01010933    SOQ56350.1    KU680289    ANI21995.1    BABH01029273    BABH01029274    BABH01029269    BABH01029270    KPJ00043.1    JQ070235    AEW43151.1    KY304474    AUN86405.1    KF777111    AHY99682.1    PZC71193.1    JQ070194    AEW43110.1    SOQ44548.1    PZC71195.1    JQ070204    AEW43120.1    KZ149974    PZC75964.1    BABH01029238    BABH01029239    BABH01029240    NWSH01000435    PCG76447.1    KU680287    ANI21993.1    GQ915324    ACZ97418.2    ODYU01010294    SOQ55304.1    BABH01029259    BABH01029260    KPJ00041.1    KPJ00042.1    JQ070231    AEW43147.1    KU680290    ANI21996.1    KPJ00056.1    JTDY01001195    KOB74579.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000053268    UP000037510   

PRIDE

G9LPT4    G9LPT3    H9JCT0    H9JJT6    G9LPT1    G9LPS9    + More
B7TZA3    G9LPS6    H9JWB6    F1DG68    Q1HPX7    G9LPS2    G9LPT0    G9LPS5    G9LPS3    H9JWE6    H9JWB7    G9LPS8    H9JWC2    H9JWB9    G9LPS4   

Pfam

PF00201   UDPGT        + More
PF00089   Trypsin

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR006326   UDPGT_MGT       
IPR033116   TRYPSIN_SER       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

G9LPT4   G9LPT3   H9JCT0   H9JJT6   M4M1W9   A0A191T1K8   + More
A0A2H1W7S2   A0A024AG00   A0A2H4WB75   A0A024AGF9   G9LPT1   A0A191T1K4   A0A0N0PE43   A0A2W1BL20   A0A191T2F8   A0A2W1BCY8   A0A2W1BEB8   G9LPP3   A0A2A4IVU8   A0A191T1L3   G9LPS9   A0A191T1M4   B7TZA3   G9LPP0   A0A191T2G1   A0A2W1B485   A0A2W1B675   A0A2H1V761   A0A191T1L8   A0A2W1BE55   A0A0N1PE65   G9LPN9   A0A2W1BEA5   A0A2W1B3V4   G9LPN3   G9LPN6   A0A140EA35   G9LPP5   A0A191T2J2   G9LPP2   A0A2W1B8D3   A0A2H4WB73   A0A2W1B475   A0A2H1VU94   G9LPN5   G9LPS6   A0A2W1B7N5   H9JWB6   A0A0N1I2R8   A0A2H1VUM4   A0A1L8D6F0   A0A1L8D6T8   F1DG68   G9LPN2   G9LPP1   Q1HPX7   A0A2W1B9W6   A0A0L7LF59   G9LPS2   A0A2W1B3X2   A0A2W1B6A2   G9LPP4   G9LPT0   A0A2W1BBH1   A0A2W1BHY3   A0A2W1B8G2   A0A2W1BDA5   A0A191T1N0   G9LPS5   A0A024AGL3   G9LPN8   G9LPN4   G9LPS3   A0A2H1WTF5   A0A191T2J5   H9JWE6   H9JWB7   A0A0N1IB27   G9LPS8   A0A2I6RJL8   A0A024AH14   A0A2W1BHP8   G9LPN7   A0A2H1VUS4   A0A2W1BA70   G9LPP7   A0A2W1BQP4   H9JWC2   A0A2A4JWQ0   A0A191T1L2   D2JLK8   A0A2H1WSA7   H9JWB9   A0A0N1ICS6   A0A0N0P9C8   G9LPS4   A0A191T2G3   A0A0N1IB34   A0A0L7LGS1  

PDB

2O6L     E-value=1.05171e-09,     Score=151

KEGG

100862842    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT33R2; UDP-glycosyltransferase UGT33R2

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016758   GO:0016021   GO:0015020   GO:0016999   GO:0004252   GO:0008152   GO:0003677   GO:0019001   GO:0031683   GO:0007165   GO:0000166   GO:0004887   GO:0003707  

Subcellular location

Membrane  

SignalP

Position:   1 - 18,         Likelihood:  0.892680

 

 

Length:

359

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.12802

Exp number, first 60 AAs:

1.9552

Total prob of N-in:

0.09895

outside

1  -  359

 

 

Pi

162.919

Theta

135.543704

Tajima's D

0.32738

CLR

0.36933

CSRT

0.466676666166692

Interpretation

Uncertain