Gene

KWMTBOMO00918

Pre Gene Modal

BGIBMGA007327

Annotation

UDP-glycosyltransferase_UGT33R1_precursor_[Bombyx_mori]

Location

Bomo_Chr2(-):6335718-6336606      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 2

CDS

ATGATCCTGAGGGTGGTCATAGCGTTAGCCTTCTGTGCGCCGCACATGCGCACGGCAAGGGTTCTTATTGTCGTGCCCACGCCGTCATACAGCCATCAACTGATCTTCCGCCCGATAATCGAAGAGCTAACTAAGAACCATCAAGTAACATTTATAACCACGAACCCAGCGTATCCAAAGGGAGATACCCCACGGAACCTCACTGAAATAGACGTGGGTCTGATCTCTTACTCGATGTGGAACCAAGAACTTTCAATAGCTAAAGACGGGAAAGACAAAGTAAAGGTCATCTTTGAGGCGACACCAAAGATATTTGCAGAGCAACTACGTTCGGCAGTTGTTGAAAAATTGATACGTAATGCCCAATTCGATCTGCTAATTTTAGAGGCTTGGTTCCGACCGGTATTGATCTGGTCGTACCTGTACAAAGCTCCCGTGTTGCTGGTCAGTTCCATGGGCACTGCTCCTGGTAACCCTGAAACCATGGGCCTGCCCAACCATTGGACTTATCACCCTTCGTTAGTTCATCAGAAGATCTACGACCTAACGACCCGTGAAAGGATTAGCAAAATGCTTAGATATCTGCACGTGCAAACGGCTTTCGATGCGAACGAGGCCAAAGAGAATGAGATTTTAAAAGGTATTTTCAATGATGCGCCTCCTCTTAGGAGTTTAAGGAGGAACGTGGACGCCATGCTCTTGAACTTGAACCCGTTGTGGGACAATAACCGTCCTTTGCCGCAGAACGTTCATTACATCGGGAATATCAATCGTAATCCTGCGAAGGAATTGCCAAGGGTGAGTTTTGTGGTCTTGTTTTATTTGTAA

Protein

MILRVVIALAFCAPHMRTARVLIVVPTPSYSHQLIFRPIIEELTKNHQVTFITTNPAYPKGDTPRNLTEIDVGLISYSMWNQELSIAKDGKDKVKVIFEATPKIFAEQLRSAVVEKLIRNAQFDLLILEAWFRPVLIWSYLYKAPVLLVSSMGTAPGNPETMGLPNHWTYHPSLVHQKIYDLTTRERISKMLRYLHVQTAFDANEAKENEILKGIFNDAPPLRSLRRNVDAMLLNLNPLWDNNRPLPQNVHYIGNINRNPAKELPRVSFVVLFYL

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.
Belongs to the peptidase S1 family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

H9JCT0   G9LPT3   H9JJT6   G9LPT4   H9JJT7   A0A0N0PE43   + More
A0A2H1V8V2   A0A024AGF9   A0A0L7LGK1   A0A0N1I2R8   A0A0L7L4H8   A0A0N1PIT5   M4M1W9   A0A191T1K4   A0A191T1M4   A0A2H4WB75   A0A2W1B675   G9LPT1   A0A2W1B7N5   G9LPP2   G9LPT0   A0A0N1PE65   A0A2W1B6A2   A0A0N1IB27   G9LPN4   A0A0L7LGS1   A0A2H1V761   A0A191T1L3   A0A0N1ICS6   A0A2H1W7S2   G9LPS9   A0A2W1BHY3   A0A191T1N0   B7TZA3   A0A0N0PEV0   A0A191T2F8   H9JWC2   A0A2H1VUM4   A0A2W1BL20   A0A191T1K8   A0A191T2G1   A0A024AG00   G9LPP3   G9LPN6   A0A2W1B3V4   H9JWB6   A0A0N1ID60   A0A2H1VUS4   G9LPP4   F1DG68   A0A0L7L346   A0A191T1L8   A0A0L7LF59   G9LPS2   A0A2W1BEB8   A0A2W1BDA5   A0A140EA35   A0A2H1VU94   A0A2W1BCY8   H9JWE7   A0A024AGL3   A0A2H4WB73   G9LPP0   A0A1L8D6F0   G9LPN5   A0A2W1B485   A0A1L8D6T8   G9LPS6   A0A2I6RJL8   A0A191T2J5   A0A2A4IVU8   G9LPP7   Q1HPX7   A0A0N1IJF4   G9LPN9   G9LPN3   D2JLK8   A0A2W1BQP4   A0A2W1B9W6   A0A2W1BE55   G9LPP5   A0A0N1IMZ0   A0A2W1B475   H9JWE4   A0A2H1WTF5   A0A024AH14   A0A2H1WSA7   A0A0N1IQG9   A0A2A4JWQ0   H9JWE6   A0A191T2J2   G9LPS5   A0A2W1BBH1   A0A0N0P9C8   G9LPP1   A0A2W1BA70   A0A2W1B3X2   G9LPT2   G9LPN7   A0A191T2G3  

EC Number

2.4.1.17

Pubmed

19121390    22155036    26354079    24698447    26227816    29027758    + More
28756777    26873292    19954531    21505429   

EMBL

BABH01040891    JQ070240    AEW43156.1    BABH01017785    JQ070241    AEW43157.1    + More
BABH01017787    BABH01017788    BABH01017789    KQ459937    KPJ19195.1    ODYU01001030    SOQ36684.1    KF777110    AHY99681.1    JTDY01001195    KOB74582.1    KQ459547    KPJ00048.1    JTDY01002978    KOB70382.1    KQ460636    KPJ13396.1    JQ747500    AGG36457.1    KU680283    ANI21989.1    KU680286    ANI21992.1    KY202945    AUC64289.1    KZ150704    PZC70375.1    JQ070238    AEW43154.1    PZC70374.1    JQ070199    AEW43115.1    JQ070237    AEW43153.1    KPJ00045.1    KZ150360    PZC71198.1    KPJ00043.1    JQ070191    AEW43107.1    KOB74579.1    SOQ36683.1    KU680288    ANI21994.1    KPJ00041.1    ODYU01006890    SOQ49139.1    BABH01029271    JQ070236    AEW43152.1    KZ150193    PZC72370.1    KU680291    ANI21997.1    FJ418685    ACJ48963.1    KQ459680    KPJ20471.1    KU680280    ANI21986.1    BABH01029238    BABH01029239    BABH01029240    ODYU01004546    SOQ44549.1    PZC72373.1    KU680282    ANI21988.1    KU680285    ANI21991.1    KF777109    AHY99680.1    JQ070200    AEW43116.1    JQ070193    AEW43109.1    PZC71192.1    KPJ20477.1    SOQ44548.1    JQ070201    AEW43117.1    HQ833816    ADY17534.1    JTDY01003324    KOB69741.1    KU680281    ANI21987.1    JTDY01001352    KOB74102.1    JQ070229    AEW43145.1    PZC71200.1    PZC72371.1    KU214506    AMK97472.1    ODYU01004485    SOQ44409.1    PZC71197.1    BABH01029275    KF777112    AHY99683.1    KY202933    AUC64277.1    JQ070197    AEW43113.1    GEYN01000093    JAV02036.1    JQ070192    AEW43108.1    PZC71199.1    GEYN01000079    JAV02050.1    JQ070233    AEW43149.1    KY304474    AUN86405.1    KU680289    ANI21995.1    NWSH01005967    PCG63789.1    JQ070204    AEW43120.1    DQ443275    ABF51364.1    KPJ19198.1    JQ070196    AEW43112.1    JQ070190    AEW43106.1    GQ915324    ACZ97418.2    KZ149974    PZC75964.1    PZC72369.1    PZC71196.1    JQ070202    AEW43118.1    KPJ00054.1    PZC71189.1    BABH01029255    ODYU01010933    SOQ56350.1    KF777111    AHY99682.1    ODYU01010294    SOQ55304.1    KPJ20473.1    NWSH01000435    PCG76447.1    BABH01029273    BABH01029274    KU680284    ANI21990.1    JQ070232    AEW43148.1    PZC71194.1    KPJ00042.1    JQ070198    AEW43114.1    PZC71195.1    PZC71202.1    JQ070239    AEW43155.1    JQ070194    AEW43110.1    KU680290    ANI21996.1   

Proteomes

UP000005204    UP000053240    UP000037510    UP000053268    UP000218220   

PRIDE

H9JCT0    G9LPT3    H9JJT6    G9LPT4    H9JJT7    G9LPT1    + More
G9LPT0    G9LPS9    B7TZA3    H9JWC2    H9JWB6    F1DG68    G9LPS2    H9JWE7    G9LPS6    Q1HPX7    H9JWE4    H9JWE6    G9LPS5    G9LPT2   

Pfam

PF00201   UDPGT        + More
PF00089   Trypsin
PF00082   Peptidase_S8

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR033116   TRYPSIN_SER       
IPR001314   Peptidase_S1A       
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR006326   UDPGT_MGT       
IPR000209   Peptidase_S8/S53_dom       
IPR036852   Peptidase_S8/S53_dom_sf       
IPR023828   Peptidase_S8_Ser-AS       

SUPFAM

SSF50494   SSF50494        + More
SSF52743   SSF52743       

Gene 3D

3.40.50.200    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JCT0   G9LPT3   H9JJT6   G9LPT4   H9JJT7   A0A0N0PE43   + More
A0A2H1V8V2   A0A024AGF9   A0A0L7LGK1   A0A0N1I2R8   A0A0L7L4H8   A0A0N1PIT5   M4M1W9   A0A191T1K4   A0A191T1M4   A0A2H4WB75   A0A2W1B675   G9LPT1   A0A2W1B7N5   G9LPP2   G9LPT0   A0A0N1PE65   A0A2W1B6A2   A0A0N1IB27   G9LPN4   A0A0L7LGS1   A0A2H1V761   A0A191T1L3   A0A0N1ICS6   A0A2H1W7S2   G9LPS9   A0A2W1BHY3   A0A191T1N0   B7TZA3   A0A0N0PEV0   A0A191T2F8   H9JWC2   A0A2H1VUM4   A0A2W1BL20   A0A191T1K8   A0A191T2G1   A0A024AG00   G9LPP3   G9LPN6   A0A2W1B3V4   H9JWB6   A0A0N1ID60   A0A2H1VUS4   G9LPP4   F1DG68   A0A0L7L346   A0A191T1L8   A0A0L7LF59   G9LPS2   A0A2W1BEB8   A0A2W1BDA5   A0A140EA35   A0A2H1VU94   A0A2W1BCY8   H9JWE7   A0A024AGL3   A0A2H4WB73   G9LPP0   A0A1L8D6F0   G9LPN5   A0A2W1B485   A0A1L8D6T8   G9LPS6   A0A2I6RJL8   A0A191T2J5   A0A2A4IVU8   G9LPP7   Q1HPX7   A0A0N1IJF4   G9LPN9   G9LPN3   D2JLK8   A0A2W1BQP4   A0A2W1B9W6   A0A2W1BE55   G9LPP5   A0A0N1IMZ0   A0A2W1B475   H9JWE4   A0A2H1WTF5   A0A024AH14   A0A2H1WSA7   A0A0N1IQG9   A0A2A4JWQ0   H9JWE6   A0A191T2J2   G9LPS5   A0A2W1BBH1   A0A0N0P9C8   G9LPP1   A0A2W1BA70   A0A2W1B3X2   G9LPT2   G9LPN7   A0A191T2G3  

KEGG

100862808    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT33R1; UDP-glycosyltransferase UGT33R1

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0016758   GO:0015020   GO:0004252   GO:0016999   GO:0008152   GO:0003677   GO:0019001   GO:0031683   GO:0007165   GO:0000166   GO:0004887   GO:0003707  

Subcellular location

Membrane  

SignalP

Position:   1 - 18,         Likelihood:  0.638466

 

 

Length:

275

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.4731

Exp number, first 60 AAs:

0.33203

Total prob of N-in:

0.03559

outside

1  -  275

 

 

Pi

243.998396

Theta

208.49763

Tajima's D

0.537648

CLR

0.427653

CSRT

0.52352382380881

Interpretation

Uncertain