Gene

KWMTBOMO00915

Pre Gene Modal

BGIBMGA009786

Annotation

G_protein_alpha_subunit_73B-like_protein_[Bombyx_mori]

Location

Bomo_Chr2(+):6305487-6320800      View in EpiBrowser

Full name

Guanine nucleotide-binding protein G(f) subunit alpha      

Alternative Name

G protein alpha f subunit

Location in the cell

Cytoplasmic   Reliability : 1.571 Mitochondrial   Reliability : 1.003 Nuclear   Reliability : 1.572

CDS

ATGCGCTTGCTACCCTGCATGAAAGGCTACGACGAAGACCAGGAGCACTCAATTGAGATAGACCGACAGATAAAGCAATGGATTAAAAATTATAACGGTGCCATAAAACTTCTGCTATTGGGTACGGGGGAGAGCGGGAAGACAACAATCATAAAACAAATGAAGATATTACATGTGCACGGATTCTCCGCGAGCGAAAGGAAAGAGAAAATTAAACATATAAAATTCAACATCCACGAATCGATATACGAGATAGTTCACAGCATGTCCCGTCTGAGCATCGCTCTGCAGAATCCGAGGAATGTGCAATCGCAACAGTACATACTGAAGATGGGTAGTGAGGGTCCTGCGGAATACACCGAGGACTACTTTGACCACGTCCGGTCGCTGTGGAGAGACGGCGGGGTCAGGGAATGTTTTAGACGATCGAACGAATATCAGCTCATTGATAGCGCCGAATATTTCCTAGACAGGATAGACTTGATAGAGAAAGAAGACTACATTCCGTCGGACAGCGATATACTTAGATGTCGTCAGAAAACGACGGGGATCCAAAAAATTGAGTTCAAAGTCAAGATACCGAAGTCGATGCAGGGCGGCGTACAAGACTTCTGGATGTTCGACGTGGGCGGCCAGAGGGGTGAAAGGAAAAAGTGGATACAGGTGTTTGAAGGTATCAACGCGATCTGGTTCTTGGTGGCTTGTAGCGACTTCGACCAAACTTTGAGGGAGGACAACACCACTAACAGACTGCAGGAGTCCTTGAACCTCTTCGAAGACGTGTGGCAGAGCAGGTTTCTTCTGGAGGCTGGGCTGATCGTGTTCCTCAACAAGCAGGACGTGCTGGAGGCGAAGGTGTCCCGGGGCCGCTCGCCCGCCACCCACTTCCCGGAGTACTCCCGGTACGAAGCGCCCGGGGACGAGTACACGAGGACCAAGCTCTTCATACGGAGTCTGTTCGTCGACTTGACCAAGAGGCAGCGGCAGCGCGCCGTGGCCGCCTCGGCCGAGCGCTTCGTCGTTGGTGAGGCCCACAGGCCCCGGGAGTGCTACTTCCACTTCACGACCGCCACGGACACTGACAATGTCCGGACCGTCTTCAGAGACGTCCACCAGATCATACTGACGCACGTGCTCAATAATATAGGCGTTTATTGA

Protein

MRLLPCMKGYDEDQEHSIEIDRQIKQWIKNYNGAIKLLLLGTGESGKTTIIKQMKILHVHGFSASERKEKIKHIKFNIHESIYEIVHSMSRLSIALQNPRNVQSQQYILKMGSEGPAEYTEDYFDHVRSLWRDGGVRECFRRSNEYQLIDSAEYFLDRIDLIEKEDYIPSDSDILRCRQKTTGIQKIEFKVKIPKSMQGGVQDFWMFDVGGQRGERKKWIQVFEGINAIWFLVACSDFDQTLREDNTTNRLQESLNLFEDVWQSRFLLEAGLIVFLNKQDVLEAKVSRGRSPATHFPEYSRYEAPGDEYTRTKLFIRSLFVDLTKRQRQRAVAASAERFVVGEAHRPRECYFHFTTATDTDNVRTVFRDVHQIILTHVLNNIGVY

Description

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Subunit

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

Similarity

Belongs to the G-alpha family.

Keywords

Complete proteome   GTP-binding   Magnesium   Metal-binding   Nucleotide-binding   Reference proteome   Transducer  

Feature

chain  Guanine nucleotide-binding protein G(f) subunit alpha

Uniprot

C7S8B5   A0A2H1VKA1   A0A2H1V4K1   A0A1E1WH23   A0A194PV43   A0A2A4IT67   + More
A0A182GFB8   T1J0Q7   A0A2L2YBB2   A0A0L0CAB9   A0A182PS00   A0A182KHB5   A0A182NIW8   A0A182QRL4   A0A182UYV6   A0A2L2Y924   A0A182U1A7   Q7Q5C3   A0A182WBW9   V5FXV5   A0A182WXB8   A0A182I4A7   A0A182LKL2   A0A182MSF7   A0A0A1XEQ1   A0A182J6P3   A0A034VWX0   A0A1B0CP62   A0A084WMK7   A0A0K8VFN9   B4KXK1   A0A182RU47   A0A182FFD7   A0A1B0F9L2   A0A1L8DKY9   B4LG44   D6WPS7   A0A1L8DKW1   A0A1A9W3D0   A0A1A9VMP1   J3JXP8   W5JV65   A0A1I8MBC1   A0A1I8NLJ5   T1P7J0   A0A1A9Y9T7   B4IXE6   W8BF42   A0A1A9ZMV4   A0A182Y7W4   B4N3N3   A0A1W4UUX8   A0A1W4XTH5   A0A1W4UHP9   A0A336KC17   B4HJR3   Q05337   N6TCS6   B4PKB5   B3M4F4   A0A0R1DYB2   A0A0Q5U5A7   A0A1B0BKB5   B3NDJ2   B4QMW7   A0A0M4ER57   A0A3B0KQS4   A0A0M3QW28   A0A3B0KGM8   B5DRG3   A0A336KDT3   A0A0R3P984   A0A226DF04   A0A0P6J5X1   A0A0J9RWM4   B0W864   A0A3B4DBY4   A0A315W5H0   A0A3B4BES1   A0A3P9MWU7   A0A3B3Y9G0   A0A087XMG4   A0A3B3U2D2   A0A3P8T4I0   A0A3P8WVI7   A0A3P8X1H9   T1KVV3   A0A3B3BI77   A0A2U9C0I1   H2LF32   A0A3P9MGI6   F1QJX7   A0A0S7I8N2   G3NS72   A0A3B4ZA44   A0A2D0QHR3   A0A1A8QQL4  

Pubmed

26354079    26483478    26561354    26108605    12364791    14747013    + More
17210077    20966253    25830018    25348373    24438588    17994087    18362917    19820115    22516182    20920257    23761445    25315136    24495485    25244985    7683429    10731132    12537572    23537049    17550304    15632085    26999592    22936249    29703783    25463417    24487278    29451363    17554307    23594743    23127152   

EMBL

EU914850    ACJ83251.1    ODYU01003018    SOQ41258.1    ODYU01000629    SOQ35739.1    + More
GDQN01004764    JAT86290.1    KQ459593    KPI96624.1    NWSH01007454    PCG62965.1    JXUM01000854    JH431739    IAAA01013835    LAA04660.1    JRES01000681    KNC29201.1    AXCN02000476    IAAA01013836    LAA04662.1    AAAB01008960    EAA11338.4    GALX01005966    JAB62500.1    APCN01002296    AXCM01016557    GBXI01005324    JAD08968.1    GAKP01012914    JAC46038.1    AJWK01021446    ATLV01024481    KE525352    KFB51451.1    GDHF01014627    JAI37687.1    CH933809    EDW18687.1    CCAG010015211    GFDF01007003    JAV07081.1    CH940647    EDW69352.1    KQ971354    EFA06864.2    GFDF01007002    JAV07082.1    BT128018    AEE62980.1    ADMH02000355    ETN66850.1    KA644437    AFP59066.1    CH916366    EDV96383.1    GAMC01009258    JAB97297.1    CH964095    EDW79238.1    UFQS01000253    UFQS01000614    UFQT01000253    UFQT01000614    SSX02041.1    SSX05412.1    SSX22418.1    CH480815    EDW41790.1    L09700    AE014296    BT064643    APGK01034946    KB740923    KB631963    ENN78094.1    ERL87498.1    CM000159    EDW94813.1    CH902618    EDV40448.1    KRK02070.1    CH954178    KQS44091.1    JXJN01015869    EDV52054.2    CM000363    EDX10759.1    CP012525    ALC44892.1    OUUW01000012    SPP87571.1    ALC43423.1    SPP87570.1    CH379070    EDY74132.1    SSX02042.1    SSX22419.1    KRT08832.1    LNIX01000021    OXA43548.1    GDUN01000344    JAN95575.1    CM002912    KMZ00089.1    DS231857    EDS38689.1    NHOQ01000318    PWA30923.1    AYCK01018842    CAEY01000614    CP026253    AWP09440.1    BX927257    GBYX01432704    JAO48610.1    HAEH01012839    SBR95831.1   

Proteomes

UP000053268    UP000218220    UP000069940    UP000037069    UP000075885    UP000075881    + More
UP000075884    UP000075886    UP000075903    UP000075902    UP000007062    UP000075920    UP000076407    UP000075840    UP000075882    UP000075883    UP000075880    UP000092461    UP000030765    UP000009192    UP000075900    UP000069272    UP000092444    UP000008792    UP000007266    UP000091820    UP000078200    UP000000673    UP000095301    UP000095300    UP000092443    UP000001070    UP000092445    UP000076408    UP000007798    UP000192221    UP000192223    UP000001292    UP000000803    UP000019118    UP000030742    UP000002282    UP000007801    UP000008711    UP000092460    UP000000304    UP000092553    UP000268350    UP000001819    UP000198287    UP000002320    UP000261440    UP000261520    UP000242638    UP000261480    UP000028760    UP000261500    UP000265080    UP000265120    UP000015104    UP000261560    UP000246464    UP000001038    UP000265180    UP000000437    UP000007635    UP000261400    UP000221080   

PRIDE

C7S8B5    Q05337    F1QJX7   

Pfam

PF00503   G-alpha        + More
PF07992   Pyr_redox_2

Interpro

IPR001019   Gprotein_alpha_su        + More
IPR027417   P-loop_NTPase       
IPR011025   GproteinA_insert       
IPR000367   Gprotein_alpha_S       
IPR023753   FAD/NAD-binding_dom       
IPR036188   FAD/NAD-bd_sf       
IPR015904   Sulphide_quinone_reductase       

SUPFAM

SSF47895   SSF47895        + More
SSF52540   SSF52540       
SSF51905   SSF51905       

Gene 3D

1.10.400.10     3.50.50.60    

CDD

cd00066  G-alpha

ProteinModelPortal

C7S8B5   A0A2H1VKA1   A0A2H1V4K1   A0A1E1WH23   A0A194PV43   A0A2A4IT67   + More
A0A182GFB8   T1J0Q7   A0A2L2YBB2   A0A0L0CAB9   A0A182PS00   A0A182KHB5   A0A182NIW8   A0A182QRL4   A0A182UYV6   A0A2L2Y924   A0A182U1A7   Q7Q5C3   A0A182WBW9   V5FXV5   A0A182WXB8   A0A182I4A7   A0A182LKL2   A0A182MSF7   A0A0A1XEQ1   A0A182J6P3   A0A034VWX0   A0A1B0CP62   A0A084WMK7   A0A0K8VFN9   B4KXK1   A0A182RU47   A0A182FFD7   A0A1B0F9L2   A0A1L8DKY9   B4LG44   D6WPS7   A0A1L8DKW1   A0A1A9W3D0   A0A1A9VMP1   J3JXP8   W5JV65   A0A1I8MBC1   A0A1I8NLJ5   T1P7J0   A0A1A9Y9T7   B4IXE6   W8BF42   A0A1A9ZMV4   A0A182Y7W4   B4N3N3   A0A1W4UUX8   A0A1W4XTH5   A0A1W4UHP9   A0A336KC17   B4HJR3   Q05337   N6TCS6   B4PKB5   B3M4F4   A0A0R1DYB2   A0A0Q5U5A7   A0A1B0BKB5   B3NDJ2   B4QMW7   A0A0M4ER57   A0A3B0KQS4   A0A0M3QW28   A0A3B0KGM8   B5DRG3   A0A336KDT3   A0A0R3P984   A0A226DF04   A0A0P6J5X1   A0A0J9RWM4   B0W864   A0A3B4DBY4   A0A315W5H0   A0A3B4BES1   A0A3P9MWU7   A0A3B3Y9G0   A0A087XMG4   A0A3B3U2D2   A0A3P8T4I0   A0A3P8WVI7   A0A3P8X1H9   T1KVV3   A0A3B3BI77   A0A2U9C0I1   H2LF32   A0A3P9MGI6   F1QJX7   A0A0S7I8N2   G3NS72   A0A3B4ZA44   A0A2D0QHR3   A0A1A8QQL4  

PDB

5UZ7     E-value=9.44199e-82,     Score=773

KEGG

100307015    K04640 guanine nucleotide-binding protein subunit alpha, other | (RefSeq) Galpha73b; G protein alpha

GO

GO:0007186   GO:0005525   GO:0003924   GO:0031683   GO:0005834   GO:0001664   GO:0007188   GO:0007498   GO:0051489   GO:0035208   GO:0016021   GO:0046872   GO:0016491   GO:0007165   GO:0007191   GO:0004871   GO:0019001   GO:0000166   GO:0004887   GO:0003707  

PANTHER

PTHR10218   PTHR10632  

Length:

385

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01454

Exp number, first 60 AAs:

0.00713

Total prob of N-in:

0.00688

outside

1  -  385

 

 

Pi

181.63987

Theta

157.17763

Tajima's D

0.517225

CLR

0.411933

CSRT

0.517474126293685

Interpretation

Uncertain