SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO00907  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA009780
Annotation
PREDICTED:_unconventional_myosin-Va_[Bombyx_mori]
Full name
Unconventional myosin-Va      
Alternative Name
Dilute myosin heavy chain, non-muscle
Myosin heavy chain p190
Myosin-V
Location in the cell
Nuclear   Reliability : 3.137
 

Sequence

CDS
ATGTCATTTGTGAAAGATGTATTTTCCTCCGTCACAGATCGCCTCTCCTCTCCGCCTTCCAATCCTAACGTCGACAGGTTCAAGCTGGAAGAGCTGGAGATTGAGAATAAGAAGCTGAAGGAGCATCTGGACAGGCTCCGCGCTGCCGGAGACAGTACTCTCGTCTCCAAGGAGGTTATCGATCAGCTGGGCGTCATACAGAAGGAGCTGGACCGGCGCCGCGACGAATGCGTCCAGCTGAAGAGCGTATTGACGAATCAAACGGTGAATCTGAAGTCGCTCGCCTCATCCAATTACGGGTCTGACGTGGACATCATTAACGAAGACGGTGAACTGGCGTCGGCCTATGAAGCGCAGAAGGGCATAAATAGACAATTACAAGAAGAGCTGACAGCCGAAAAGGAATTCTATTCGAAGCACATATCGTCCGCTAAGGCCGAAATCGAGAGACTACGGGAAGAGAACGAAAAATATCAGAAGCTGCTGAGCGCGGACCTGAGCCAAGACCCGAAGGACAAGAGCCATGAGTTCGCGCAGAACGAGATCATCAGGCTGGCCTCAGAAAGTCTGGCTCTACAGGAGCGGGTCGACAAGTTGTCGGAGAGCTGTCGCCGCTACAAGAATCAGATACGGATGCTCGTCAACAAACTCAAGGAGGTCGGCGTTGATGACGTCACCGACATCCTCGAGGGTAGCGACCCGGTGGCGGCGCCCAGCGCTTCGGTCTCGCTGAACATGGCGCCGGTCACCCGGAAGAAGGAGAGGGAGTACCTCGGCATGTTCGAGTACAGGATACAGGACGAGCCCACCATCATAAAGAAACTTATAACCGATTTGAAACCGAAAGTGGCGACCACGCTGCTGCCGGGCCTGCCCGCCTACATCCTGTTCATGATGCTGCGCCACACGGACCACGTGGACGACGAGCCCAAGATGCACCAGCTCATGAAGGCGGTGCGGAACGGCGTCAAGAAGACCCTGAAGAAGCGATCGGACAGCATCGAGTACAACGCGCTGTGGCTCGCCAACATGCTGAGGCTAGTACACGAAGCCCCCCACAGTGTCCCCCCAGTCGTCCCCCCCTAG
Protein
MSFVKDVFSSVTDRLSSPPSNPNVDRFKLEELEIENKKLKEHLDRLRAAGDSTLVSKEVIDQLGVIQKELDRRRDECVQLKSVLTNQTVNLKSLASSNYGSDVDIINEDGELASAYEAQKGINRQLQEELTAEKEFYSKHISSAKAEIERLREENEKYQKLLSADLSQDPKDKSHEFAQNEIIRLASESLALQERVDKLSESCRRYKNQIRMLVNKLKEVGVDDVTDILEGSDPVAAPSASVSLNMAPVTRKKEREYLGMFEYRIQDEPTIIKKLITDLKPKVATTLLPGLPAYILFMMLRHTDHVDDEPKMHQLMKAVRNGVKKTLKKRSDSIEYNALWLANMLRLVHEAPHSVPPVVPP

Summary

Description
Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity).
Subunit
May be a homodimer, which associates with multiple calmodulin or myosin light chains.
Similarity
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Keywords
3D-structure   Actin-binding   ATP-binding   Calmodulin-binding   Coiled coil   Complete proteome   Direct protein sequencing   Golgi apparatus   Membrane   Motor protein   Myosin   Nucleotide-binding   Phosphoprotein   Reference proteome   Repeat  
Feature
chain  Unconventional myosin-Va
EMBL
BABH01017762    BABH01017763    BABH01017764    ODYU01000388    SOQ35087.1    NWSH01001891    + More
PCG69780.1    KQ460280    KPJ16326.1    GDQN01009645    JAT81409.1    GDQN01006058    JAT84996.1    KQ459593    KPI96619.1    NEVH01001344    PNF43034.1    JTDY01006044    KOB66343.1    GDRN01089955    JAI60557.1    GDRN01089957    JAI60556.1    GALX01003268    JAB65198.1    KQ971354    EFA06975.2    HM212671    ADM15669.1    IACF01007780    LAB73363.1    AAZX01001194    LBMM01000310    KMR01422.1    NNAY01000532    OXU27842.1    GL445235    EFN90001.1    GL436993    EFN71292.1    GL888719    EGI58273.1    KQ976464    KYM84426.1    KQ981382    KYN42143.1    KQ434822    KZC07080.1    GECZ01014290    JAS55479.1    GFWV01023237    MAA47964.1    GFJQ02005527    JAW01443.1    LJIG01002798    KRT84142.1    ADTU01022924    ADTU01022925    GACK01002599    JAA62435.1    GEDV01009513    JAP79044.1    GEGO01002425    JAR92979.1    LN830727    CFW94236.1    GBBM01003505    JAC31913.1    KQ977279    KYN04261.1    GFAC01003801    JAT95387.1    GFAA01003816    JAT99618.1    ABJB010176425    ABJB010253897    ABJB010408395    ABJB010674318    ABJB010823393    ABJB011044382    DS854257    EEC13680.1    GL440553    EFN65790.1    KB632326    ERL92471.1    PZQS01000002    PVD36507.1    GEBQ01022099    JAT17878.1    GEDC01028278    GEDC01006987    JAS09020.1    JAS30311.1    APGK01035149    APGK01035150    APGK01035151    KB740923    ENN78188.1    AMQN01015508    KB311976    ELT88116.1    GEZM01031022    JAV85121.1    KU193727    AMB26737.1    AMQM01001739    KB097639    ESN92553.1    GDIQ01018624    JAN76113.1    GDIQ01061683    JAN33054.1    GDIQ01108817    JAL42909.1    GDIQ01170346    GDIQ01136811    GDIQ01030299    LRGB01003163    JAK81379.1    KZS03930.1    GDIP01017260    JAM86455.1    GDIQ01141357    JAL10369.1    GDIQ01086333    JAN08404.1    GDIQ01214230    JAK37495.1    GDIP01140471    JAL63243.1    GDIP01235456    JAI87945.1    GDIQ01106515    JAL45211.1    GDIP01088479    JAM15236.1    GDIQ01041893    JAN52844.1    GDIQ01106568    JAL45158.1    GDIQ01090022    JAN04715.1    GDIQ01152952    JAK98773.1    GDIP01096726    JAM06989.1    GDIP01052936    JAM50779.1    KB202284    ESO90956.1    HACA01031851    CDW49212.1    GL732599    EFX72449.1    DS235019    EEB10549.1    KB518028    EMP38954.1    AAWZ02028717    AAWZ02028718    AAWZ02028719    AAWZ02028720    AAWZ02028721    AKHW03006295    KYO21221.1    KYO21220.1    X67251    Z11718    AGCU01054991    AGCU01054992    AGCU01054993    AGCU01054994    AGCU01054995    MCFN01000225    OXB62270.1    KK575648    KFW10242.1    KK502053    KFP20202.1    AADN05000047    EU921839    ACH48182.1    AC133947    CT033761    NBAG03000224    PNI74812.1    NDHI03003424    PNJ54992.1    AC010674    AC018902    AC025917    KF459554    KZ505660    PKU48095.1    KL671826    KFW83660.1    LMAW01000003    KQL61248.1    AWGT02000059    OXB79964.1    KK709155    KFQ32240.1    ABQF01017076   
Pfam
PF01843   DIL        + More
PF00063   Myosin_head
PF00612   IQ
PF07662   Nucleos_tra2_C
PF01773   Nucleos_tra2_N
PF02736   Myosin_N
PF00400   WD40
Interpro
IPR002710   Dilute_dom        + More
IPR000048   IQ_motif_EF-hand-BS       
IPR036961   Kinesin_motor_dom_sf       
IPR001609   Myosin_head_motor_dom       
IPR027417   P-loop_NTPase       
IPR002668   CNT_N_dom       
IPR011657   CNT_C_dom       
IPR036103   MYSc_Myo5       
IPR008989   Myosin_S1_N       
IPR004009   Myosin_N       
IPR017986   WD40_repeat_dom       
IPR001680   WD40_repeat       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       
IPR037988   Myo5a_CBD       
SUPFAM
SSF52540   SSF52540        + More
SSF50084   SSF50084       
SSF50978   SSF50978       
Gene 3D
PDB
4J5M     E-value=2.42545e-23,     Score=269

Ontologies

Topology

Subcellular location
Golgi apparatus membrane  
Length:
361
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.30585
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00891
outside
1  -  361
 
 

Population Genetic Test Statistics

Pi
300.849489
Theta
162.975979
Tajima's D
2.673306
CLR
0.082177
CSRT
0.95885205739713
Interpretation
Uncertain
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