SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO00904
Annotation
IMFamide_precursor_[Bombyx_mori]
Full name
Neuropeptide IMFamide       + More
Neuropeptide SIFamide      
SIFamide-related peptide      
FMRFamide-related neuropeptides      
Alternative Name
TYRKPPFNGSIF-amide
AYKKPPFNGSIF-amide
Location in the cell
Extracellular   Reliability : 1.93
 

Sequence

CDS
ATGTCGAGAGCTGTAATGAGAATGACAGTCACTTTCTGCATTGTAGCCATCTTGTTGTGTCTGTTGGACTTCAGCGAGGCTAACTACAAAAACGCACCGATGAATGGAATTATGTTCGGAAAAAGGGGACCTACGGATTATGATTCACGTAGCAAGACTTTCACTGCTTTGTGTGAGATTGCTACCGAAGCTTGTCAGGCGTGGTTCCCGACACAAGAAAACTAG
Protein
MSRAVMRMTVTFCIVAILLCLLDFSEANYKNAPMNGIMFGKRGPTDYDSRSKTFTALCEIATEACQAWFPTQEN

Summary

Description
Ligand for the neuropeptide SIFamide receptor.
Ligand for the neuropeptide SIFamide receptor (PubMed:16378592). Modulates sexual behavior by negatively regulating female receptivity to male courtship and by playing a role in male sex discrimination (PubMed:17126293, PubMed:26469541). Also involved in promoting sleep (PubMed:24658384).
GYRKPPFNGSIF-amide may be involved in olfaction and contraction of hindgut.
Similarity
Belongs to the FARP (FMRFamide related peptide) family.
Keywords
Amidation   Cleavage on pair of basic residues   Direct protein sequencing   Neuropeptide   Secreted   Signal   Complete proteome   Reference proteome   Behavior   Glycoprotein  
Feature
peptide  Neuropeptide IMFamide
EMBL
AB298924    BAG50363.1    KT005973    ALM30324.1    ODYU01000382    SOQ35072.1    + More
MH028089    AXY04258.1    AGBW02008086    OWR54173.1    JTDY01000896    KOB75515.1    KQ459593    KPI96617.1    KC340927    AGH25559.1    KQ460890    KPJ11039.1    KC340937    AGH25569.1    KPI96616.1    KPJ11038.1    KQ971354    EFA07409.1    MH028128    AXY04297.1    LC146524    BAV78828.1    GAKP01003510    JAC55442.1    KT005992    ALM30343.1    CH933808    EDW09188.1    CH940648    EDW61556.2    CH916367    EDW02244.1    MF765484    AXF48204.1    AB817280    BAO00977.1    CH902619    EDV37789.1    GQ253922    ACT35307.1    CCAG010014920    JXJN01009092    KK854331    PTY14740.1    CH477618    EAT38218.1    AFFK01020457    UFQT01001614    SSX31166.1    KB632322    ERL92324.1    CH964274    EDW85214.1    JXUM01086664    JXUM01090606    GAPW01006812    KQ563852    KQ563583    JAC06786.1    KXJ73167.1    KXJ73634.1    AJVK01059044    AB298923    BAG50362.1    GL442298    EFN63630.1    KQ979266    KYN22052.1    GFDL01004610    JAV30435.1    ADTU01012083    CM000158    EDW92564.1    KX531964    ANY27774.1    CH480838    EDW49218.1    CH954179    EDV57030.1    CM000362    CM002911    EDX08576.1    KMY96377.1    AF376801    AE013599    BT030932    BT030951    BT030970    BT032699    BK003637    AAO15386.1    ABV82333.1    DAA02335.1    KK107347    QOIP01000007    EZA52345.1    RLU20085.1    KQ976558    KYM80712.1    AXCM01006861    KZ288242    PBC31251.1    OUUW01000001    SPP73743.1    CM000071    EDY69487.2    ATLV01024071    KE525348    KFB50485.1    KQ435818    KOX72529.1    JR053277    AEY61896.1    KX273323    AOH96653.1    MG550188    AWT50622.1    HG326274    CDG15340.1    KQ977012    KYN06355.1    KQ414646    KOC66362.1    ABLF02035181    PYGN01001011    PSN38497.1    EU117384    ABV21807.1    CVRI01000059    CRL03065.1    AAZX01001191    NNAY01002644    OXU20876.1    AB036712    AB036713    BAC55939.1    KK119629    KFM76246.1    ABJB010961237    GQ214556    DS939604    ADD92393.1    EEC18288.1   

Ontologies

Topology

Subcellular location
Secreted  
SignalP
Position:   1 - 27,         Likelihood:  0.995773
 
 
Length:
74
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
16.88995
Exp number, first 60 AAs:
16.88787
Total prob of N-in:
0.32259
POSSIBLE N-term signal
sequence
outside
1  -  4
TMhelix
5  -  22
inside
23  -  74
 
 

Population Genetic Test Statistics

Pi
238.978765
Theta
140.564627
Tajima's D
2.454272
CLR
0
CSRT
0.935703214839258
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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