Gene

KWMTBOMO00904

Annotation

IMFamide_precursor_[Bombyx_mori]

Location

Bomo_Chr2(+):6112087-6113527      View in EpiBrowser

Full name

Neuropeptide IMFamide       + More
Neuropeptide SIFamide      
SIFamide-related peptide      
FMRFamide-related neuropeptides      

Alternative Name

TYRKPPFNGSIF-amide
AYKKPPFNGSIF-amide

Location in the cell

Extracellular   Reliability : 1.93

CDS

ATGTCGAGAGCTGTAATGAGAATGACAGTCACTTTCTGCATTGTAGCCATCTTGTTGTGTCTGTTGGACTTCAGCGAGGCTAACTACAAAAACGCACCGATGAATGGAATTATGTTCGGAAAAAGGGGACCTACGGATTATGATTCACGTAGCAAGACTTTCACTGCTTTGTGTGAGATTGCTACCGAAGCTTGTCAGGCGTGGTTCCCGACACAAGAAAACTAG

Protein

MSRAVMRMTVTFCIVAILLCLLDFSEANYKNAPMNGIMFGKRGPTDYDSRSKTFTALCEIATEACQAWFPTQEN

Description

Ligand for the neuropeptide SIFamide receptor.
Ligand for the neuropeptide SIFamide receptor (PubMed:16378592). Modulates sexual behavior by negatively regulating female receptivity to male courtship and by playing a role in male sex discrimination (PubMed:17126293, PubMed:26469541). Also involved in promoting sleep (PubMed:24658384).
GYRKPPFNGSIF-amide may be involved in olfaction and contraction of hindgut.

Similarity

Belongs to the FARP (FMRFamide related peptide) family.

Keywords

Amidation   Cleavage on pair of basic residues   Direct protein sequencing   Neuropeptide   Secreted   Signal   Complete proteome   Reference proteome   Behavior   Glycoprotein  

Feature

peptide  Neuropeptide IMFamide

Uniprot

B3IUC8   A0A0S1U2C1   A0A2H1V3Y6   A0A385H8W0   C0HKU0   A0A212FKA6   + More
A0A0L7LJA7   A0A194PTH9   M4QEL7   A0A194R0I8   C0HKV8   M4QEM6   A0A194PT72   A0A194QZR6   D6WT77   A0A385H900   A0A1E1G7V9   A0A034WM50   A0A0S1U0F6   B4KQ60   B4LJI8   B4J814   A0A1I8NTC4   A0A345BEF2   U3U8T5   A0A1I8N4A9   B3MG86   C7E6V5   A0A240SWE5   A0A1B0FN31   A0A1B0AH03   A0A1A9YDA0   A0A1B0B6I1   A0A2R7W6Z4   Q16UM4   T1IZI5   A0A336MLL6   U4UED8   B4NLH5   A0A023ED68   A0A240SYM7   B3IUC7   A0A1W4WV12   E2ASG4   A0A151JAR6   A0A1Q3FS99   A0A158NCY6   A0A182FER3   A0A1W4WB88   B4PBD2   A0A1B2AKW2   B4IH42   B3NQU7   B4QC21   Q6IGX9   A0A026W8G3   A0A195B903   A0A182MX73   A0A182WL10   A0A2A3EJN8   A0A182Y265   A0A3B0J3C8   A0A182NJP9   B5E199   A0A084WJU1   A0A0M8ZZ52   V9IML1   A0A182VFN0   A0A1C8Y949   A0A1S3CVV7   W0UTB3   A0A087ZMZ7   A0A195D0B1   A0A0L7R661   J9M924   A0A2P8Y2L2   A7Y330   A0A1J1IWY1   K7JPC8   A0A232ERG7   Q867W1   A0A087UFV7   B7QHG6  

Pubmed

30171635    29466015    22118469    26227816    26354079    18362917    + More
19820115    25348373    17994087    23932938    25315136    20958806    17510324    23537049    24945155    26483478    20798317    25641051    21347285    17550304    22936249    10731132    12537572    14709175    15219831    16378592    17126293    24658384    26469541    24508170    30249741    25244985    15632085    24438588    29403074    18308319    20075255    28648823    14723891    19824085   

EMBL

AB298924    BAG50363.1    KT005973    ALM30324.1    ODYU01000382    SOQ35072.1    + More
MH028089    AXY04258.1    AGBW02008086    OWR54173.1    JTDY01000896    KOB75515.1    KQ459593    KPI96617.1    KC340927    AGH25559.1    KQ460890    KPJ11039.1    KC340937    AGH25569.1    KPI96616.1    KPJ11038.1    KQ971354    EFA07409.1    MH028128    AXY04297.1    LC146524    BAV78828.1    GAKP01003510    JAC55442.1    KT005992    ALM30343.1    CH933808    EDW09188.1    CH940648    EDW61556.2    CH916367    EDW02244.1    MF765484    AXF48204.1    AB817280    BAO00977.1    CH902619    EDV37789.1    GQ253922    ACT35307.1    CCAG010014920    JXJN01009092    KK854331    PTY14740.1    CH477618    EAT38218.1    AFFK01020457    UFQT01001614    SSX31166.1    KB632322    ERL92324.1    CH964274    EDW85214.1    JXUM01086664    JXUM01090606    GAPW01006812    KQ563852    KQ563583    JAC06786.1    KXJ73167.1    KXJ73634.1    AJVK01059044    AB298923    BAG50362.1    GL442298    EFN63630.1    KQ979266    KYN22052.1    GFDL01004610    JAV30435.1    ADTU01012083    CM000158    EDW92564.1    KX531964    ANY27774.1    CH480838    EDW49218.1    CH954179    EDV57030.1    CM000362    CM002911    EDX08576.1    KMY96377.1    AF376801    AE013599    BT030932    BT030951    BT030970    BT032699    BK003637    AAO15386.1    ABV82333.1    DAA02335.1    KK107347    QOIP01000007    EZA52345.1    RLU20085.1    KQ976558    KYM80712.1    AXCM01006861    KZ288242    PBC31251.1    OUUW01000001    SPP73743.1    CM000071    EDY69487.2    ATLV01024071    KE525348    KFB50485.1    KQ435818    KOX72529.1    JR053277    AEY61896.1    KX273323    AOH96653.1    MG550188    AWT50622.1    HG326274    CDG15340.1    KQ977012    KYN06355.1    KQ414646    KOC66362.1    ABLF02035181    PYGN01001011    PSN38497.1    EU117384    ABV21807.1    CVRI01000059    CRL03065.1    AAZX01001191    NNAY01002644    OXU20876.1    AB036712    AB036713    BAC55939.1    KK119629    KFM76246.1    ABJB010961237    GQ214556    DS939604    ADD92393.1    EEC18288.1   

Proteomes

UP000007151    UP000037510    UP000053268    UP000053240    UP000007266    UP000009192    + More
UP000008792    UP000001070    UP000095300    UP000095301    UP000007801    UP000091820    UP000092444    UP000092445    UP000092443    UP000092460    UP000008820    UP000030742    UP000007798    UP000069940    UP000249989    UP000092462    UP000192223    UP000000311    UP000078492    UP000005205    UP000069272    UP000192221    UP000002282    UP000001292    UP000008711    UP000000304    UP000000803    UP000053097    UP000279307    UP000078540    UP000075883    UP000075920    UP000242457    UP000076408    UP000268350    UP000075884    UP000001819    UP000030765    UP000053105    UP000075903    UP000079169    UP000005203    UP000078542    UP000053825    UP000007819    UP000245037    UP000183832    UP000002358    UP000215335    UP000054359    UP000001555   

PRIDE

B3IUC8    B3IUC7    Q6IGX9   

ProteinModelPortal

B3IUC8   A0A0S1U2C1   A0A2H1V3Y6   A0A385H8W0   C0HKU0   A0A212FKA6   + More
A0A0L7LJA7   A0A194PTH9   M4QEL7   A0A194R0I8   C0HKV8   M4QEM6   A0A194PT72   A0A194QZR6   D6WT77   A0A385H900   A0A1E1G7V9   A0A034WM50   A0A0S1U0F6   B4KQ60   B4LJI8   B4J814   A0A1I8NTC4   A0A345BEF2   U3U8T5   A0A1I8N4A9   B3MG86   C7E6V5   A0A240SWE5   A0A1B0FN31   A0A1B0AH03   A0A1A9YDA0   A0A1B0B6I1   A0A2R7W6Z4   Q16UM4   T1IZI5   A0A336MLL6   U4UED8   B4NLH5   A0A023ED68   A0A240SYM7   B3IUC7   A0A1W4WV12   E2ASG4   A0A151JAR6   A0A1Q3FS99   A0A158NCY6   A0A182FER3   A0A1W4WB88   B4PBD2   A0A1B2AKW2   B4IH42   B3NQU7   B4QC21   Q6IGX9   A0A026W8G3   A0A195B903   A0A182MX73   A0A182WL10   A0A2A3EJN8   A0A182Y265   A0A3B0J3C8   A0A182NJP9   B5E199   A0A084WJU1   A0A0M8ZZ52   V9IML1   A0A182VFN0   A0A1C8Y949   A0A1S3CVV7   W0UTB3   A0A087ZMZ7   A0A195D0B1   A0A0L7R661   J9M924   A0A2P8Y2L2   A7Y330   A0A1J1IWY1   K7JPC8   A0A232ERG7   Q867W1   A0A087UFV7   B7QHG6  

KEGG

100174833    no KO assigned | (RefSeq) IMFa; IMFamide

GO

GO:0005576   GO:0007218   GO:0016021   GO:0071855   GO:0048047   GO:0045938   GO:0048018   GO:0007621   GO:0005184   GO:0005615   GO:0005179   GO:0042752  

Subcellular location

Secreted  

SignalP

Position:   1 - 27,         Likelihood:  0.995773

 

 

Length:

74

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

16.88995

Exp number, first 60 AAs:

16.88787

Total prob of N-in:

0.32259

POSSIBLE N-term signal

sequence

outside

1  -  4

TMhelix

5  -  22

inside

23  -  74

 

 

Pi

238.978765

Theta

140.564627

Tajima's D

2.454272

CLR

0

CSRT

0.935703214839258

Interpretation

Uncertain