Gene

KWMTBOMO00850

Pre Gene Modal

BGIBMGA009676

Annotation

PREDICTED:_4-coumarate--CoA_ligase_1-like_[Bombyx_mori]

Location

Bomo_Chr2(-):4387573-4394201      View in EpiBrowser

Full name

Luciferin 4-monooxygenase      

Location in the cell

Cytoplasmic   Reliability : 2.041

CDS

ATGTATAGGCCGGCCATTCTAGATCCAGAGCTCAGTAGTCTGAACATAAGAGGATGGCACCACATCTCTGGTCTGCTGGCTGTCTCGGCAGCAATGGCTTTTGGAAGGAGAGGTCTGTACCTGGATAATTTCGAATTGGAATTATTTTTGAAAACAATCGAGAAATATAAGGTAGCTCAGGTGGTCGTGGCGCCTACAGTTCTGGTCGCAATGTGTAAAAGCGACGCTAAATACGACTTGAGCTCTTTAAGATTTATATATTCATCGGTCGCTCCACTACACAAGGAGACGATAAGCGCTGCTTATAAAAAATTGCCCAACCTTAAAGCCGTCCTCCAGGGCTACGGTTCGTCGGAGACCACGCTGGTCATCATCAGATACACGTACAAAGATGCGGATATAGTCAAGTCCGGCAGCGTGGGACTGGTCGCTCCCAATTGTATCGTGAAGGTGGTCGACATAAAAGATCAAAGACCCTTAGGACCAAATCAGGAAGGGGAAATCTACGTAAAGGGTCCGCTCCTCATGAAGGGCTACATGGGGAGGGCCAGGTCCGACGACTTCGATGACGAAGGCTTCTACAGGACCGGGGACGCGGGCTACTATGACGAGGATGGACACTTCTACATCTGCGACAGGATTAAGGAATTCATCAAATGCCACGGATACCAGGTTCCACCAGCTGAAGTAGAAGCTGTGTTACTCCTGCATGACGCAGTAAGAGAAGCCGGCGTTATCGGGCTGAAGGATCCGGATGCCGGGGAGATTCCACTGGCCTTCGTCTCTTTACAGCCAGGGAAGGAAGTCACCGAAGAGGAATTGAAGGAGTTTGTTGCGAAACGGGTCGGTGTGAGATTTGCTATGAGATGGTCGCGAATGCTTATGACGTGCACCACGGATAAACATGTCAAATAA

Protein

MYRPAILDPELSSLNIRGWHHISGLLAVSAAMAFGRRGLYLDNFELELFLKTIEKYKVAQVVVAPTVLVAMCKSDAKYDLSSLRFIYSSVAPLHKETISAAYKKLPNLKAVLQGYGSSETTLVIIRYTYKDADIVKSGSVGLVAPNCIVKVVDIKDQRPLGPNQEGEIYVKGPLLMKGYMGRARSDDFDDEGFYRTGDAGYYDEDGHFYICDRIKEFIKCHGYQVPPAEVEAVLLLHDAVREAGVIGLKDPDAGEIPLAFVSLQPGKEVTEEELKEFVAKRVGVRFAMRWSRMLMTCTTDKHVK

Description

Produces green light with a wavelength of 544 nm.
Produces green light.

Catalytic Activity

ATP + firefly D-luciferin + O2 = AMP + CO2 + diphosphate + firefly oxyluciferin + hnu

Cofactor

Mg(2+)

Similarity

Belongs to the peptidase S1 family.
Belongs to the ATP-dependent AMP-binding enzyme family.

Keywords

3D-structure   ATP-binding   Luminescence   Magnesium   Metal-binding   Monooxygenase   Nucleotide-binding   Oxidoreductase   Peroxisome   Photoprotein  

Feature

chain  Luciferin 4-monooxygenase

Uniprot

H9JJH5   H9JJH4   A0A2A4JYH7   I4DPZ6   A0A194PT23   A0A194QZM0   + More
A0A194QZV5   A0A194PT28   A0A194PZH5   A0A194R162   A0A194R547   A0A194R0D8   A0A2H1VNT1   A0A194PUZ5   A0A212FIH9   A0A194PUB9   A0A212FII9   A0A1B0DFB0   H9J2F6   A0A084VAF2   G8GE17   A0A182YM73   A0A240PK82   A0A1Y9H2Q7   A0A182Q5M2   A0A194PHR8   F5HJ76   A0A182TRT7   A0A1I8JTE0   A0A1I8JVD9   A0A182WW21   A0A182TA88   A0A2J7QLT8   A0A194QRL9   A0A240PLR9   A0A194RK67   A0A2C9GUN5   A0A1Y9IUV9   A0A0C6DRW5   A0A1I8JUE9   A0A2J7QLX8   A0A2A4JNM0   A0A067R342   A0A182PST3   A0A182QEY9   A0A2M4BJK7   A0A2H1WNI5   A0A182YEP9   A0A2M4BJS1   A0A2M4BJN0   A0A2M4BJM2   A0A1B0GIW0   A0A1L8DYF7   A0A182SUG3   A0A212EHJ8   A0A1L8DYB2   A0A2A4J232   A0A2H1VTP5   A0A182RE74   H9J5X9   A0A2A4JN67   A0A182LQ72   A0A182I9E2   Q7Q503   A0A182VPX3   D2KV87   A0A2W1BTP3   A0A182JWZ3   A0A084W803   A0A182X4T0   A0A0L7LP26   E3WI50   A0A1Q2TT48   P13129   A0A2A4JMM7   A0A182HDU2   A0A182NN52   A0A1I8JVD6   A7US60   A0A1Q3FYK1   A0A0A1X815   A0A182KX68   A0A1Y9H2R4   Q05KC0   A0A3F2YLV6   H1AD94   A0A1Q2TT53   Q01158   Q2ABY2   A0A194PPL0   A0A1I8JVX6   A0A1I8JV25   Q27348   Q17Q43   A0A182JKD8   A0A240PPP9   A0A182LZJ7   A0A2A4K7K9   A0A1I8JTC1   Q1WLP6  

EC Number

1.13.12.7

Pubmed

19121390    22651552    26354079    22118469    24438588    25244985    + More
12364791    14747013    17210077    24845553    20966253    20004235    28756777    26227816    2473944    26483478    25830018    30456363    1610896    16380223    10380103    17510324    17002879   

EMBL

BABH01017564    BABH01017566    BABH01017567    NWSH01000380    PCG76826.1    AK403861    + More
BAM19986.1    KQ459593    KPI96566.1    KQ460890    KPJ10988.1    KPJ10987.1    KPI96571.1    KPI96565.1    KPJ10990.1    KPJ10986.1    KPJ10989.1    ODYU01003402    SOQ42112.1    KPI96564.1    AGBW02008380    OWR53543.1    KPI96568.1    OWR53544.1    AJVK01015100    AJVK01015101    AJVK01015102    AJVK01015103    BABH01007891    ATLV01003206    KE524124    KFB34946.1    JN127350    AET05796.1    AXCN02000090    KQ459604    KPI92264.1    AAAB01008820    EGK96337.1    APCN01002222    NEVH01013241    PNF29543.1    KQ461181    KPJ07625.1    KQ460045    KPJ18228.1    AXCM01004086    AB251887    BAQ25864.1    PNF29548.1    NWSH01001030    PCG73033.1    KK852730    KDR17523.1    AXCN02002214    GGFJ01004115    MBW53256.1    ODYU01009511    SOQ54004.1    GGFJ01004113    MBW53254.1    GGFJ01004116    MBW53257.1    GGFJ01004114    MBW53255.1    AJWK01017694    AJWK01017695    AJWK01017696    GFDF01002635    JAV11449.1    AGBW02014874    OWR40957.1    GFDF01002634    JAV11450.1    NWSH01003686    PCG65919.1    ODYU01004352    SOQ44136.1    BABH01029979    BABH01029980    PCG73034.1    APCN01008266    AAAB01008961    EAA11995.3    AB479114    BAI66602.1    KZ149903    PZC78438.1    ATLV01021336    KE525316    KFB46347.1    JTDY01000482    KOB76976.1    AB603803    BAJ41367.1    AB908263    BAW94790.1    M26194    PCG73036.1    JXUM01130360    KQ567568    KXJ69363.1    EDO64449.2    GFDL01002418    JAV32627.1    GBXI01007236    JAD07056.1    AB255748    BAF34360.1    AB644226    BAL46510.1    AB909130    BAW94791.1    X66919    AB220162    BAE80731.1    KQ459597    KPI94913.1    U49182    AY192561    Z49891    AAA91472.1    AAO39674.1    CAA90072.1    CH477187    EAT48873.1    AXCM01000327    NWSH01000060    PCG80059.1    DQ137139    AAZ74651.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000092462    + More
UP000030765    UP000076408    UP000075885    UP000075884    UP000075886    UP000007062    UP000075902    UP000075840    UP000075903    UP000076407    UP000075901    UP000235965    UP000075881    UP000075883    UP000075920    UP000075900    UP000027135    UP000092461    UP000075882    UP000037510    UP000069940    UP000249989    UP000008820    UP000075880   

PRIDE

H9JJH5    H9JJH4    H9J2F6    G8GE17    H9J5X9   

Pfam

PF00501   AMP-binding        + More
PF13193   AMP-binding_C
PF00089   Trypsin
PF00855   PWWP
PF00856   SET
PF17907   AWS

Interpro

IPR000873   AMP-dep_Synth/Lig        + More
IPR042099   AMP-dep_Synthh-like_sf       
IPR025110   AMP-bd_C       
IPR020845   AMP-binding_CS       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR033116   TRYPSIN_SER       
IPR027380   Luciferase-like_N_sf       
IPR011011   Znf_FYVE_PHD       
IPR001965   Znf_PHD       
IPR013083   Znf_RING/FYVE/PHD       
IPR000313   PWWP_dom       
IPR001214   SET_dom       
IPR006560   AWS_dom       

SUPFAM

SSF50494   SSF50494        + More
SSF57903   SSF57903       

Gene 3D

3.40.50.12780     4.10.8.10     3.30.40.10    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JJH5   H9JJH4   A0A2A4JYH7   I4DPZ6   A0A194PT23   A0A194QZM0   + More
A0A194QZV5   A0A194PT28   A0A194PZH5   A0A194R162   A0A194R547   A0A194R0D8   A0A2H1VNT1   A0A194PUZ5   A0A212FIH9   A0A194PUB9   A0A212FII9   A0A1B0DFB0   H9J2F6   A0A084VAF2   G8GE17   A0A182YM73   A0A240PK82   A0A1Y9H2Q7   A0A182Q5M2   A0A194PHR8   F5HJ76   A0A182TRT7   A0A1I8JTE0   A0A1I8JVD9   A0A182WW21   A0A182TA88   A0A2J7QLT8   A0A194QRL9   A0A240PLR9   A0A194RK67   A0A2C9GUN5   A0A1Y9IUV9   A0A0C6DRW5   A0A1I8JUE9   A0A2J7QLX8   A0A2A4JNM0   A0A067R342   A0A182PST3   A0A182QEY9   A0A2M4BJK7   A0A2H1WNI5   A0A182YEP9   A0A2M4BJS1   A0A2M4BJN0   A0A2M4BJM2   A0A1B0GIW0   A0A1L8DYF7   A0A182SUG3   A0A212EHJ8   A0A1L8DYB2   A0A2A4J232   A0A2H1VTP5   A0A182RE74   H9J5X9   A0A2A4JN67   A0A182LQ72   A0A182I9E2   Q7Q503   A0A182VPX3   D2KV87   A0A2W1BTP3   A0A182JWZ3   A0A084W803   A0A182X4T0   A0A0L7LP26   E3WI50   A0A1Q2TT48   P13129   A0A2A4JMM7   A0A182HDU2   A0A182NN52   A0A1I8JVD6   A7US60   A0A1Q3FYK1   A0A0A1X815   A0A182KX68   A0A1Y9H2R4   Q05KC0   A0A3F2YLV6   H1AD94   A0A1Q2TT53   Q01158   Q2ABY2   A0A194PPL0   A0A1I8JVX6   A0A1I8JV25   Q27348   Q17Q43   A0A182JKD8   A0A240PPP9   A0A182LZJ7   A0A2A4K7K9   A0A1I8JTC1   Q1WLP6  

PDB

2D1S     E-value=1.03527e-54,     Score=538

KEGG

101746546    no KO assigned | (RefSeq) 4-coumarate--CoA ligase 1-like

GO

GO:0003824   GO:0016874   GO:0004497   GO:0004252   GO:0016021   GO:0008218   GO:0047077   GO:0005524   GO:0005777   GO:0046872   GO:0005634   GO:0018024   GO:0008152   GO:0019674   GO:0006741   GO:0005737   GO:0006396   GO:0000166   GO:0004887   GO:0003707  

Subcellular location

Peroxisome  

Length:

304

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.65964

Exp number, first 60 AAs:

2.64911

Total prob of N-in:

0.12884

outside

1  -  304

 

 

Pi

227.334283

Theta

167.632196

Tajima's D

1.218813

CLR

0.01292

CSRT

0.71866406679666

Interpretation

Uncertain