Gene

KWMTBOMO00843

Pre Gene Modal

BGIBMGA009756

Annotation

PREDICTED:_NAD_kinase_2?_mitochondrial_[Papilio_xuthus]

Location

Bomo_Chr2(+):4223692-4255705      View in EpiBrowser

Full name

NAD kinase 2, mitochondrial      

Alternative Name

NAD kinase domain-containing protein 1, mitochondrial

Location in the cell

Nuclear   Reliability : 2.016

CDS

ATGGACAAATGTCTGATTGTTTCAAAGGCCACAAGATACGACTACGAAAAACATAGTCACGATAATATATCGGACGTGGAGTTGGAGAGGATATTGAGGCAGCGCGGTTCAGACTACGACATGATCATGGCGAACCACAGAGAACAGAAGGCGTTTGAGGAGGGCATCGCGAAAAATCTCAAGGACATGGGCATCAAGGTTGAAATGGCTAGCAGACGTACGTACAATGATGAATTGATAAAGTGGTGCGACGTTGTGGTGCCCTGTGGTGGGGACGGAACTTTTTTATTGGCGGCCTCAAGAGTCCGAGATCCCAATAAGCCCGTGATAGGTTTGAACAGCGCCCCGCACAAGTCCGTGGGACGTCTCTGTCTGCCCACGTGGTGCTCGAACGATGTGAAGGGCGCGCTCCACGCCCTCAAGGAGGGTCGATTCCGTTGGATGCGTCGTTCAAGGATACGCACGACGGTCACCTGCGAACCTAAACACCTGGACACCATCACGCCAGTCGACTTACACACGCTGCATTACAGCAGGTACCCGCCTGTGCATAGCGCAGAATACAACACAGACACCAAGAGGCCACTCGGAATAGACGCACAAGGAGATAACTCCACATTGGCCACCAAGGTTCTGCCGTTTCTGGCGTTGAATGAGGTTTTCATAGGCGAGAGCGTGACGTCTAGGGTTTCGGTACTGAGGTTGCAGATCGACAACGGCAAGTGGACGCACACGAAAAGCTCCGGCCTCTGCGTGACCACCGGAACCGGAAGCACCTCCTGGCATTTCAGCATAAACTGCCTCAGAACGCATTCGGTTCTCGAACTGATGAAGATACTGGCCCAAGATTACAACGTTAAGCTCGACACGAGTCTAGAGAAAGCCCGGGAGGTCGCCGAGAGATACAACAAGAAGCTCATGTTCGGACCTGAATCGGAGCAGCTCGCATATTCAGTCCGGGAGTACATAACTTTCGAGGAGTGGCCGGCGCCGCGGGGGCTGCGCGTCCGGGACCGCGCGTCCGCCGTCTGCGTGCGCTCGCACTGCACTGACGCAGGGCTAGTCATAGACGGCAGTGTATCCTTCCCGTTCAACGACGGTACTGAGGCTCTCCTGGAGATCCACCCGGAGGACTCCCTTATGACCGTGCAAATGGACGACGCTTTACCGTATTGA

Protein

MDKCLIVSKATRYDYEKHSHDNISDVELERILRQRGSDYDMIMANHREQKAFEEGIAKNLKDMGIKVEMASRRTYNDELIKWCDVVVPCGGDGTFLLAASRVRDPNKPVIGLNSAPHKSVGRLCLPTWCSNDVKGALHALKEGRFRWMRRSRIRTTVTCEPKHLDTITPVDLHTLHYSRYPPVHSAEYNTDTKRPLGIDAQGDNSTLATKVLPFLALNEVFIGESVTSRVSVLRLQIDNGKWTHTKSSGLCVTTGTGSTSWHFSINCLRTHSVLELMKILAQDYNVKLDTSLEKAREVAERYNKKLMFGPESEQLAYSVREYITFEEWPAPRGLRVRDRASAVCVRSHCTDAGLVIDGSVSFPFNDGTEALLEIHPEDSLMTVQMDDALPY

Description

Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.

Catalytic Activity

ATP + NAD(+) = ADP + H(+) + NADP(+)

Subunit

Homodimer.

Similarity

Belongs to the NAD kinase family.

Uniprot

A0A2A4JE36   A0A194PTD1   H9JJQ5   A0A2H1WCV6   A0A1B6LJF1   A0A336M694   + More
A0A0P8Y9R6   A0A2M4CZ06   A0A1W4XA49   A0A084WLA9   A0A182FI19   A0A2M4CZD3   A0A139WFG2   B4HSL5   B4QGR4   A0A182GS85   A0A2M4ABB9   A0A1W4UZL1   A0A0J9TX13   A0A1W4UKK0   A0A182IU51   A0A2M4AB88   U5ESU0   B3N813   A0A2M4ABK4   A0A3B0J0Z7   A0A0Q5WBL6   B3MI79   A0A2M4CZH6   B4P3W5   Q7JW73   A0A182QXL7   A0A0R1DM91   A0A2M3ZJ41   A0A0B4KEG0   A0A1B6HFF9   Q16PA6   A0A2M4BQE7   A0A2M4BQ59   A0A2M4BQI2   A0A0J9R8N9   A0A2M4BPN3   Q28ZC2   B4GHY7   A0A1W4UY06   A0A182N7J4   A0A0Q5WN98   A0A0J9R8R7   A0A067R3M2   B4LM04   A0A0R3NU88   A0A1W4UYB5   B4NN31   A0A182PEY3   A0A2J7PVN7   A0A0R1DNE8   A0A0B4KFF1   A0A0Q5WBM1   B0WPH7   A0A0R1DPJ6   A0A0B4KEH3   A0A0U2T6A2   A0A182LVA5   A0A2J7PVP5   B4J5B1   A0A0R3NN20   A0A0B4KF27   A0A1Q3FED9   A0A0R3NT48   A0A182R9A3   A0A0Q9W2L6   A0A182YJI7   A0A1I8NEL6   A0A034WMS2   A0A0L0C4K1   A0A182K9Y3   A0A0Q9W209   A0A182THQ9   A0A182I698   A0A0K8WMA3   A0A1I8NEL7   A0A182UJW3   A0A182L441   B4KLK8   W8BBD2   A0A182X237   Q7QIB7   A0A1L8E135   A0A1I8NEL9   A0A1J1I3G2   A0A034WK75   E9GJF7   A0A0P5NSD0   A0A182WI70  

EC Number

2.7.1.23

Pubmed

26354079    19121390    17994087    24438588    18362917    19820115    + More
22936249    26483478    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17510324    15632085    24845553    26621068    25244985    25315136    25348373    26108605    20966253    24495485    12364791    14747013    17210077    21292972   

EMBL

NWSH01001879    PCG69824.1    KQ459593    KPI96562.1    BABH01017556    BABH01017557    + More
BABH01017558    BABH01017559    ODYU01007744    SOQ50786.1    GEBQ01016243    JAT23734.1    UFQS01000392    UFQT01000392    SSX03532.1    SSX23897.1    CH902619    KPU75891.1    GGFL01006394    MBW70572.1    ATLV01024210    KE525350    KFB51003.1    GGFL01006393    MBW70571.1    KQ971352    KYB26619.1    CH480816    EDW47042.1    CM000362    CM002911    EDX06289.1    KMY92423.1    JXUM01016837    KQ560467    KXJ82262.1    GGFK01004764    MBW38085.1    KMY92425.1    GGFK01004733    MBW38054.1    GANO01003078    JAB56793.1    CH954177    EDV59426.1    GGFK01004818    MBW38139.1    OUUW01000001    SPP74437.1    KQS70816.1    EDV35924.1    GGFL01006507    MBW70685.1    CM000157    EDW89448.1    AE013599    AY118304    AAF58993.2    AAM48333.1    AXCN02000576    KRJ98447.1    GGFM01007734    MBW28485.1    AGB93351.1    GECU01034222    GECU01029133    JAS73484.1    JAS78573.1    CH477789    EAT36195.1    GGFJ01006010    MBW55151.1    GGFJ01006011    MBW55152.1    GGFJ01005887    MBW55028.1    KMY92427.1    GGFJ01005889    MBW55030.1    CM000071    EAL25691.1    CH479183    EDW36107.1    KQS70818.1    KMY92426.1    KK852727    KDR17625.1    CH940648    EDW59924.1    KRT02464.1    CH964282    EDW85770.1    NEVH01020945    PNF20402.1    KRJ98446.1    AGB93348.1    KQS70817.1    DS232024    EDS32365.1    KRJ98445.1    AGB93350.1    KT754278    ALS04112.1    AXCM01006814    PNF20401.1    CH916367    EDW01753.1    KRT02465.1    AGB93349.1    GFDL01009126    JAV25919.1    KRT02463.1    KRF79154.1    GAKP01003879    GAKP01003877    JAC55073.1    JRES01000930    KNC27215.1    KRF79155.1    APCN01003600    GDHF01000031    JAI52283.1    CH933808    EDW08644.2    GAMC01008015    JAB98540.1    AAAB01008807    EAA04760.4    GFDF01001644    JAV12440.1    CVRI01000035    CRK92897.1    GAKP01003880    GAKP01003878    JAC55074.1    GL732547    EFX80504.1    GDIQ01148689    JAL03037.1   

Proteomes

UP000218220    UP000053268    UP000005204    UP000007801    UP000192223    UP000030765    + More
UP000069272    UP000007266    UP000001292    UP000000304    UP000069940    UP000249989    UP000192221    UP000075880    UP000008711    UP000268350    UP000002282    UP000000803    UP000075886    UP000008820    UP000001819    UP000008744    UP000075884    UP000027135    UP000008792    UP000007798    UP000075885    UP000235965    UP000002320    UP000075883    UP000001070    UP000075900    UP000076408    UP000095301    UP000037069    UP000075881    UP000075902    UP000075840    UP000075882    UP000009192    UP000076407    UP000007062    UP000183832    UP000000305    UP000075920   

PRIDE

H9JJQ5    Q7JW73   

Pfam

PF01513   NAD_kinase

Interpro

IPR016064   NAD/diacylglycerol_kinase_sf        + More
IPR017438   ATP-NAD_kinase_N       
IPR002504   NADK       
IPR017437   ATP-NAD_kinase_PpnK-typ_C       
IPR012355   NADK2_mit       

SUPFAM

SSF111331   SSF111331       

Gene 3D

2.60.200.30     3.40.50.10330    

ProteinModelPortal

A0A2A4JE36   A0A194PTD1   H9JJQ5   A0A2H1WCV6   A0A1B6LJF1   A0A336M694   + More
A0A0P8Y9R6   A0A2M4CZ06   A0A1W4XA49   A0A084WLA9   A0A182FI19   A0A2M4CZD3   A0A139WFG2   B4HSL5   B4QGR4   A0A182GS85   A0A2M4ABB9   A0A1W4UZL1   A0A0J9TX13   A0A1W4UKK0   A0A182IU51   A0A2M4AB88   U5ESU0   B3N813   A0A2M4ABK4   A0A3B0J0Z7   A0A0Q5WBL6   B3MI79   A0A2M4CZH6   B4P3W5   Q7JW73   A0A182QXL7   A0A0R1DM91   A0A2M3ZJ41   A0A0B4KEG0   A0A1B6HFF9   Q16PA6   A0A2M4BQE7   A0A2M4BQ59   A0A2M4BQI2   A0A0J9R8N9   A0A2M4BPN3   Q28ZC2   B4GHY7   A0A1W4UY06   A0A182N7J4   A0A0Q5WN98   A0A0J9R8R7   A0A067R3M2   B4LM04   A0A0R3NU88   A0A1W4UYB5   B4NN31   A0A182PEY3   A0A2J7PVN7   A0A0R1DNE8   A0A0B4KFF1   A0A0Q5WBM1   B0WPH7   A0A0R1DPJ6   A0A0B4KEH3   A0A0U2T6A2   A0A182LVA5   A0A2J7PVP5   B4J5B1   A0A0R3NN20   A0A0B4KF27   A0A1Q3FED9   A0A0R3NT48   A0A182R9A3   A0A0Q9W2L6   A0A182YJI7   A0A1I8NEL6   A0A034WMS2   A0A0L0C4K1   A0A182K9Y3   A0A0Q9W209   A0A182THQ9   A0A182I698   A0A0K8WMA3   A0A1I8NEL7   A0A182UJW3   A0A182L441   B4KLK8   W8BBD2   A0A182X237   Q7QIB7   A0A1L8E135   A0A1I8NEL9   A0A1J1I3G2   A0A034WK75   E9GJF7   A0A0P5NSD0   A0A182WI70  

PDB

1Y3H     E-value=0.00603377,     Score=93

KEGG

101746269    K00858 NAD+ kinase [EC:2.7.1.23] | (RefSeq) NAD kinase 2, mitochondrial

PATHWAY

00760    Nicotinate and nicotinamide metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0006741   GO:0003951   GO:0019674   GO:0005524   GO:0042803   GO:0005739   GO:0008152   GO:0005737   GO:0006396   GO:0000166   GO:0004887   GO:0003707   GO:0016021  

Subcellular location

Mitochondrion  

Length:

391

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01862

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01602

outside

1  -  391

 

 

Pi

240.44257

Theta

144.558278

Tajima's D

2.305199

CLR

0.047269

CSRT

0.924203789810509

Interpretation

Uncertain