Gene

KWMTBOMO00842

Pre Gene Modal

BGIBMGA009755

Annotation

PREDICTED:_protein_lunapark-B_[Papilio_machaon]

Location

Bomo_Chr2(+):4195532-4216645      View in EpiBrowser

Full name

Endoplasmic reticulum junction formation protein lunapark-B      

Alternative Name

ER junction formation factor lunapark

Location in the cell

Nuclear   Reliability : 2.665

CDS

ATGGGCCTTATAATTTCAAGATTTCGCCGCAAGAAAACAACAACAGAAATACTCGAACGACTAGAAAACGATATAAAAAGCATAGAAAGAGATGGCCAATACAAGGAGCAAACCCACAAACGCGTTATAGGATACGTTATGGCGTATTCAGTGGGTCTATACGTGTTATTTGCGGTCCTTTACTACTACATGTACGTGGGGAGGAGTCAGTATTGGTTGCATTCGTTGCTGTATGCCTCGCCTTTACTGGTTTTGCCCGTGCTTGTGATATTCTTACGGTCATCAATATCCTGGTATTATAATTGGATGATAAACAAGAACAGGATGAAGTTAAGCAAAATGAGGGAGGATAAAAAGAAGATATTGGAAGAGGTGATGAACACAGAGACATATAAGGTTGCCAAAGAAATCCTTGACAAATACGGAAGTCCAGACGACCAGTCGAAATCGTTGAAGCCGTTCGTACCAACCCTGAACGTACCCGGTAATCTTCCTAGTTCACCCCCAGCAACACCGGGACAGTTAAGGCAGAGACAGCTAGCGTTGCAGACTTCGACGCCCATACCGAATAAAATGAACATGTTGGCTATAAACAACACGCCGAATGCTCTGTACAAAGGACCGCGTCTTAGATCGGACCAGTTGCCCAGGCCACTGCTCGACAAGGACCGGTCTGCTCTCGACAAAGTGGTGGACTATCTTCTCAAGGACGGACCGAATCATCGGATGGCGCTGATATGCAGGGAATGCTTCTCGCACAACGGCATGGCGATGGCCGAAGAGTACGAGTACGTGTCGTACGTGTGCGCGTACTGCGGGCGTCTCAACCCGGCGCGGAAGCAGAGGCCGGCCGCGCCGCTGCTGAGCCCGAAGGCGCTGCCGCCGGCCGTAAGGAGGATGCACGGTGGAAGTGACGATTCTTCGGTAGCCAGTTCCGGAAGTGAAAGCGAAGACGAGAAGAATGGAGGAAATCATTGTAATAATTTTGAGAAATCGATGAGCGAGTCGGATCGTCCCCCCTCCCCGGTTGAGGCGGACCCGAAATCCGACGAAGAAAAAAAAGAAGACTGA

Protein

MGLIISRFRRKKTTTEILERLENDIKSIERDGQYKEQTHKRVIGYVMAYSVGLYVLFAVLYYYMYVGRSQYWLHSLLYASPLLVLPVLVIFLRSSISWYYNWMINKNRMKLSKMREDKKKILEEVMNTETYKVAKEILDKYGSPDDQSKSLKPFVPTLNVPGNLPSSPPATPGQLRQRQLALQTSTPIPNKMNMLAINNTPNALYKGPRLRSDQLPRPLLDKDRSALDKVVDYLLKDGPNHRMALICRECFSHNGMAMAEEYEYVSYVCAYCGRLNPARKQRPAAPLLSPKALPPAVRRMHGGSDDSSVASSGSESEDEKNGGNHCNNFEKSMSESDRPPSPVEADPKSDEEKKED

Description

Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within three-way ER tubular junction network (By similarity).

Subunit

Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.

Similarity

Belongs to the lunapark family.

Keywords

Coiled coil   Complete proteome   Endoplasmic reticulum   Membrane   Metal-binding   Reference proteome   Transmembrane   Transmembrane helix   Zinc   Zinc-finger  

Feature

chain  Endoplasmic reticulum junction formation protein lunapark-B

Uniprot

A0A194QZV1   A0A194PT16   A0A212EIF6   E1ZW26   A0A158NSC4   A0A0J7NTR1   + More
A0A151I2S0   F4W5K3   A0A026W7Y3   A0A0C9RAD4   A0A088AUC3   A0A151JQL9   K7IP88   A0A2J7Q6Q7   A0A195D3X0   A0A0L7RBQ8   A0A2M4ASJ5   A0A0T6BCI7   A0A1Y1MZT0   A0A2P8Z7C9   A0A067QZC6   U5EPS4   T1HY37   A0A2M3ZKM9   A0A1A9WYU8   A0A1B6BWI0   A0A2M3ZAW2   A0A2A3EMU7   A0A023EYR4   A0A2M4BND6   A0A310SLU3   A0A1I8M1X2   A0A034VPA0   A0A182G051   T1GJ40   A0A0K8T8R3   A0A0K8V1G2   A0A069DSM8   A0A224XLN1   D6WRW1   A0A0A9YZY6   A0A182LRW0   A0A182RJ89   V4B9A4   A0A1Q3F482   A0A0K8TQ24   A0A1Q3F469   A0A1Q3F3Q9   A0A1Q3F3J7   A0A1Q3F3H5   A0A1Q3F3M4   A0A3B1IET6   A0A3B1IK64   A0A1Q3F3F1   A0A1Q3F3I5   A0A3B1KDJ3   A0A0A1X2G5   H2ZLJ1   W4ZIZ9   Q7Q3Q4   F1QDW0   A0A182W7F9   Q6PFM4   A0A232F464   A0A182WT26   A0A182L1X5   A0A0R4IYI7   W5JG27   A0A182HV23   A0A182Q1I5   A0A182VBE5   A0A1S4GXK9   B0XAQ3   A0A1A9XDG8   A0A336LNE8   A0A1B0BNG4   A0A1S4K935   A0A0P4WMA9   A0A0N7ZLN7   A0A0N7ZQ27   A0A0P6GQ79   A0A0P6DJE7   Q17D88   A0A0P6DM87   A0A0P6DY44   A0A182NTL3   F6WQS5   A0A1B0AFV8   A0A0P5ESW4   A0A0P5DTN3   A0A0P5XQR1   A0A0N8CDE9   A0A0P5YC81   A0A0P4YQQ0   A0A0P6EWN3   A0A0N7ZW88   A0A0N8CIQ7   A0A0N8CMN2  

Pubmed

26354079    22118469    20798317    21347285    21719571    24508170    + More
30249741    20075255    28004739    29403074    24845553    25474469    25315136    25348373    26334808    18362917    19820115    25401762    26823975    23254933    26369729    25329095    25830018    12364791    23594743    28648823    20966253    20920257    23761445    17510324    12481130    15114417   

EMBL

KQ460890    KPJ10982.1    KQ459593    KPI96561.1    AGBW02014667    OWR41251.1    + More
GL434758    EFN74613.1    ADTU01024816    LBMM01001759    KMQ95805.1    KQ976543    KYM80985.1    GL887655    EGI70500.1    KK107348    QOIP01000010    EZA52212.1    RLU17934.1    GBYB01005220    JAG74987.1    KQ978642    KYN29499.1    NEVH01017460    PNF24266.1    KQ976881    KYN07583.1    KQ414617    KOC68357.1    GGFK01010430    MBW43751.1    LJIG01001931    KRT85009.1    GEZM01016728    GEZM01016727    JAV91164.1    PYGN01000163    PSN52408.1    KK853162    KDR10430.1    GANO01000066    JAB59805.1    ACPB03014864    GGFM01008325    MBW29076.1    GEDC01031657    JAS05641.1    GGFM01004880    MBW25631.1    KZ288205    PBC33133.1    GBBI01004399    JAC14313.1    GGFJ01005458    MBW54599.1    KQ763832    OAD54707.1    GAKP01015005    JAC43947.1    CAQQ02005852    CAQQ02005853    CAQQ02005854    GBRD01003880    GBRD01003879    JAG61942.1    GDHF01019874    JAI32440.1    GBGD01001791    JAC87098.1    GFTR01005698    JAW10728.1    KQ971351    EFA06588.1    GBHO01008509    GBHO01008508    GBHO01008506    GDHC01021193    JAG35095.1    JAG35096.1    JAG35098.1    JAP97435.1    AXCM01008268    KB203274    ESO85439.1    GFDL01012684    JAV22361.1    GDAI01001134    JAI16469.1    GFDL01012679    JAV22366.1    GFDL01012851    JAV22194.1    GFDL01012946    JAV22099.1    GFDL01012952    JAV22093.1    GFDL01012947    JAV22098.1    GFDL01012960    JAV22085.1    GFDL01012942    JAV22103.1    GBXI01009464    JAD04828.1    AAGJ04152145    AAAB01008964    EAA12393.2    BX546447    CT573297    BC057494    NNAY01001020    OXU25465.1    ADMH02001321    ETN63021.1    APCN01002491    AXCN02000795    DS232592    EDS43842.1    UFQT01000093    SSX19612.1    JXJN01017383    GDIP01254271    JAI69130.1    GDIP01233241    JAI90160.1    GDIP01223721    JAI99680.1    GDIQ01042623    JAN52114.1    GDIQ01085717    JAN09020.1    CH477298    EAT44341.1    GDIQ01090207    JAN04530.1    GDIQ01085718    GDIQ01085716    JAN09019.1    EAAA01000296    GDIP01143799    JAJ79603.1    GDIP01151398    JAJ72004.1    GDIP01068632    JAM35083.1    GDIP01142655    JAL61059.1    GDIP01059844    JAM43871.1    GDIP01225246    JAI98155.1    GDIQ01056966    JAN37771.1    GDIP01206433    JAJ16969.1    GDIP01127791    LRGB01000512    JAL75923.1    KZS18895.1    GDIP01116791    JAL86923.1   

Proteomes

UP000053240    UP000053268    UP000007151    UP000000311    UP000005205    UP000036403    + More
UP000078540    UP000007755    UP000053097    UP000279307    UP000005203    UP000078492    UP000002358    UP000235965    UP000078542    UP000053825    UP000245037    UP000027135    UP000015103    UP000091820    UP000242457    UP000095301    UP000069272    UP000015102    UP000007266    UP000075883    UP000075900    UP000030746    UP000018467    UP000007875    UP000007110    UP000007062    UP000000437    UP000075920    UP000215335    UP000076407    UP000075882    UP000000673    UP000075840    UP000075886    UP000075903    UP000002320    UP000092443    UP000092460    UP000008820    UP000075884    UP000008144    UP000092445    UP000076858   

PRIDE

Q6PFM4   

Pfam

PF10058   zinc_ribbon_10        + More
PF02866   Ldh_1_C
PF00919   UPF0004
PF01938   TRAM
PF04055   Radical_SAM
PF00056   Ldh_1_N

Interpro

IPR040115   Lnp        + More
IPR019273   Lunapark_dom       
IPR022383   Lactate/malate_DH_C       
IPR015955   Lactate_DH/Glyco_Ohase_4_C       
IPR036291   NAD(P)-bd_dom_sf       
IPR006463   MiaB_methiolase       
IPR005839   Methylthiotransferase       
IPR001236   Lactate/malate_DH_N       
IPR006638   Elp3/MiaB/NifB       
IPR023404   rSAM_horseshoe       
IPR013848   Methylthiotransferase_N       
IPR002792   TRAM_dom       
IPR007197   rSAM       
IPR020612   Methylthiotransferase_CS       
IPR038135   Methylthiotransferase_N_sf       

SUPFAM

SSF51735   SSF51735        + More
SSF56327   SSF56327       

Gene 3D

3.90.110.10     3.40.50.12160     3.80.30.20    

ProteinModelPortal

A0A194QZV1   A0A194PT16   A0A212EIF6   E1ZW26   A0A158NSC4   A0A0J7NTR1   + More
A0A151I2S0   F4W5K3   A0A026W7Y3   A0A0C9RAD4   A0A088AUC3   A0A151JQL9   K7IP88   A0A2J7Q6Q7   A0A195D3X0   A0A0L7RBQ8   A0A2M4ASJ5   A0A0T6BCI7   A0A1Y1MZT0   A0A2P8Z7C9   A0A067QZC6   U5EPS4   T1HY37   A0A2M3ZKM9   A0A1A9WYU8   A0A1B6BWI0   A0A2M3ZAW2   A0A2A3EMU7   A0A023EYR4   A0A2M4BND6   A0A310SLU3   A0A1I8M1X2   A0A034VPA0   A0A182G051   T1GJ40   A0A0K8T8R3   A0A0K8V1G2   A0A069DSM8   A0A224XLN1   D6WRW1   A0A0A9YZY6   A0A182LRW0   A0A182RJ89   V4B9A4   A0A1Q3F482   A0A0K8TQ24   A0A1Q3F469   A0A1Q3F3Q9   A0A1Q3F3J7   A0A1Q3F3H5   A0A1Q3F3M4   A0A3B1IET6   A0A3B1IK64   A0A1Q3F3F1   A0A1Q3F3I5   A0A3B1KDJ3   A0A0A1X2G5   H2ZLJ1   W4ZIZ9   Q7Q3Q4   F1QDW0   A0A182W7F9   Q6PFM4   A0A232F464   A0A182WT26   A0A182L1X5   A0A0R4IYI7   W5JG27   A0A182HV23   A0A182Q1I5   A0A182VBE5   A0A1S4GXK9   B0XAQ3   A0A1A9XDG8   A0A336LNE8   A0A1B0BNG4   A0A1S4K935   A0A0P4WMA9   A0A0N7ZLN7   A0A0N7ZQ27   A0A0P6GQ79   A0A0P6DJE7   Q17D88   A0A0P6DM87   A0A0P6DY44   A0A182NTL3   F6WQS5   A0A1B0AFV8   A0A0P5ESW4   A0A0P5DTN3   A0A0P5XQR1   A0A0N8CDE9   A0A0P5YC81   A0A0P4YQQ0   A0A0P6EWN3   A0A0N7ZW88   A0A0N8CIQ7   A0A0N8CMN2  

KEGG

101741327    K23292 endoplasmic reticulum junction formation protein lunapark | (RefSeq) protein lunapark-B-like

GO

GO:0071786   GO:0016021   GO:0005975   GO:0016616   GO:0071782   GO:1903373   GO:0071788   GO:0098826   GO:0042802   GO:0046872   GO:0030176   GO:0051539   GO:0016740   GO:0006400  

PANTHER

PTHR22166  

Subcellular location

Endoplasmic reticulum membrane   Localizes at endoplasmic reticulum (ER) three-way tubular junctions, which represent crossing-points at which the tubules build a polygonal network.   With evidence from 3 publications.

Length:

356

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

45.3959100000001

Exp number, first 60 AAs:

17.96154

Total prob of N-in:

0.99235

POSSIBLE N-term signal

sequence

inside

1  -  41

TMhelix

42  -  64

outside

65  -  78

TMhelix

79  -  101

inside

102  -  356

 

 

Pi

229.65927

Theta

155.847956

Tajima's D

1.493094

CLR

0.024366

CSRT

0.787610619469027

Interpretation

Uncertain