Gene

KWMTBOMO00827

Pre Gene Modal

BGIBMGA009689

Annotation

PREDICTED:_androgen-dependent_TFPI-regulating_protein-like_[Bombyx_mori]

Location

Bomo_Chr2(-):3642464-3646536      View in EpiBrowser

Full name

Androgen-dependent TFPI-regulating protein      

Alternative Name

Androgen-dependent-expressed protein FAR-17a

Location in the cell

PlasmaMembrane   Reliability : 4.51

CDS

ATGCACATCAGTAATCTTCTTTACATACAGTACGCCATATTATCAGCTAATGTCAGCGAAGGGTCCATGGAGAATTTCGGAACAGGCACCTTCAAAAATATGGAGTATCGATATTTTACTACTTGGACCGCGGGTCTACAGATAGGATATGCGGCGCTAGGTACACTCTGCGATCTTCTGGTGCTGCTAAATAGACACAAAGAGAACTACAGATTACCTAAATATTTGGGTTCGTCGCGGGAAATTATATTCGCTGGTCTGGTCTGGCCGTCTAGTTGGGTAGTCTTCACTGTATTTTGGACTTTATTACACTACGACAGAAGCCTGATATTCCCAGCTTACTTGGACAAGATCATAACGCGTCTATCTAACCACGTCATACATACAATGATCGTTCCGGTCGTGGTCTGGGAGGTGATGTTTTGGCCCAGGAAACCGAAAAGTCACTACAGGAACATCGCGCAACTGGCGATACACATGTTGGCGTACATCTTCGTGTTACATTTCACTTATCACGAGCACGGCGTCTGGCTGTACCCGATCTTCAAAGCAGTTCAAGGAACGATACATTTCTATCTGCTCCACTTTTATGTCGCAGCTATGTGCTTGATGTTCTACAGGCTTCAGTGGTGGTTGAACTCTGTGATCCACGGCGTCGAAGACGTTGAGAAGATTCGCTTCATAGATTCAGCTGTAGGAAGATTCAGCTATAGGAAGTGGTTTACTTGGGCAATGTTACACGAGAGATCACAAAGCCGCATATAA

Protein

MHISNLLYIQYAILSANVSEGSMENFGTGTFKNMEYRYFTTWTAGLQIGYAALGTLCDLLVLLNRHKENYRLPKYLGSSREIIFAGLVWPSSWVVFTVFWTLLHYDRSLIFPAYLDKIITRLSNHVIHTMIVPVVVWEVMFWPRKPKSHYRNIAQLAIHMLAYIFVLHFTYHEHGVWLYPIFKAVQGTIHFYLLHFYVAAMCLMFYRLQWWLNSVIHGVEDVEKIRFIDSAVGRFSYRKWFTWAMLHERSQSRI

Description

Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro).

Miscellaneous

Expression was reduced after castration and reappeared after testosterone treatments.

Similarity

Belongs to the AIG1 family.

Keywords

Alternative splicing   Cell membrane   Complete proteome   Membrane   Polymorphism   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Androgen-dependent TFPI-regulating protein
splice variant  In isoform 2.
sequence variant  In dbSNP:rs2076185.

Uniprot

H9JJI8   H9JJI9   A0A2A4ISD3   S4P4C5   A0A194R0B8   A0A194PSZ5   + More
A0A212F7H0   A0A2H1WGM3   A0A2A4ITZ9   A0A194PTA5   I4DJC6   A0A194R142   A0A1E1W9D6   A0A2H1WWJ5   A0A2A4J503   T1IBD8   A0A0D9R570   A0A2D4I7W0   A0A2K6D6X9   A0A2D4GB73   A0A2K6D6W2   A0A2J7PDG0   A0A2K5MJD1   A0A096NKY2   A0A2K5MJC9   A0A2K5JJ01   A0A2I3N3A2   G3WW37   A0A2K6KYY2   A0A2K6RGG7   A0A2K5MJC8   A0A2K5WPU0   A0A1D5Q198   H9EXV2   G7P4F3   M3XJ79   A0A2J8WN06   F7FVQ1   A0A2I3ML13   G7MQK8   H2PHY1   H9GE02   A0A2R9ASQ7   A0A2I3RF37   A0A2K5Y9N0   Q96IZ2   A0A2R9AV55   G3S0A2   Q96IZ2-3   G3R864   A0A1B6DTE3   F7DN37   F7EH87   A0A2K6KZ03   A0A1U7TW54   A0A2K5CIT5   A0A2I3HSN3   M3WAX6   A0A2Y9FZ49   Q60534   A0A195BSL9   A0A195D3P2   A0A151XB65   A0A2D0SL66   Q8C138   G3T4W4   A0A2K5RAU8   A0A2D0SL67   A0A1B6CZW9   A0A0R4J0W3   A0A2I0MXL7   A0A023EZS5   A0A171B0S5   A0A341D0B8   K7FA11   A0A091R2W3   H0Z5X2   F1RV85  

Pubmed

19121390    23622113    26354079    22118469    22651552    21709235    + More
25362486    17431167    25319552    22002653    9215903    21881562    22722832    16136131    14702039    14574404    15489334    21868574    22398555    25243066    17975172    2045681    16141072    19468303    23371554    25474469    17381049    20360741   

EMBL

BABH01017488    BABH01017486    BABH01017487    NWSH01008210    PCG62651.1    GAIX01006034    + More
JAA86526.1    KQ460890    KPJ10969.1    KQ459593    KPI96546.1    AGBW02009872    OWR49681.1    ODYU01008534    SOQ52219.1    PCG62652.1    KPI96547.1    AK401394    BAM18016.1    KPJ10970.1    GDQN01007452    JAT83602.1    ODYU01011594    SOQ57431.1    NWSH01003298    PCG66594.1    ACPB03005685    AQIB01159356    IACK01084098    LAA80299.1    IACJ01112898    LAA57005.1    NEVH01026389    PNF14352.1    AHZZ02024143    AEFK01063730    AEFK01063731    AEFK01063732    AEFK01063733    AEFK01063734    AEFK01063735    AQIA01052761    AQIA01052762    JSUE03030254    JSUE03030255    JU323455    AFE67211.1    CM001279    EHH52716.1    AFYH01049129    AFYH01049130    AFYH01049131    AFYH01049132    NDHI03003384    PNJ71145.1    CM001256    EHH17956.1    ABGA01392235    ABGA01392236    ABGA01392237    ABGA01392238    ABGA01392239    ABGA01392240    ABGA01392241    ABGA01392242    AAWZ02016749    AAWZ02016750    AAWZ02016751    AJFE02097058    AACZ04065924    NBAG03000244    PNI62836.1    AK313114    AK300919    AL022724    CH471087    BC007011    CABD030043317    CABD030043318    CABD030043319    GEDC01008352    JAS28946.1    GAMQ01004936    JAB36915.1    ADFV01015550    ADFV01015551    ADFV01015552    AANG04001101    M80427    KQ976419    KYM89277.1    KQ976885    KYN07518.1    KQ982335    KYQ57538.1    AK029025    AK135327    AC165263    BC027755    GEDC01024428    GEDC01024128    GEDC01022375    GEDC01018863    GEDC01018435    GEDC01006808    JAS12870.1    JAS13170.1    JAS14923.1    JAS18435.1    JAS18863.1    JAS30490.1    AKCR02000001    PKK34427.1    GBBI01004723    JAC13989.1    GEMB01000406    JAS02715.1    AGCU01199960    KK712361    KFQ34135.1    ABQF01024175    AEMK02000051   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000015103    + More
UP000029965    UP000233120    UP000235965    UP000233060    UP000028761    UP000233080    UP000007648    UP000233180    UP000233200    UP000233100    UP000006718    UP000009130    UP000008672    UP000001595    UP000001646    UP000240080    UP000002277    UP000233140    UP000005640    UP000001519    UP000008225    UP000189704    UP000233020    UP000001073    UP000011712    UP000248480    UP000189706    UP000078540    UP000078542    UP000075809    UP000221080    UP000000589    UP000007646    UP000233040    UP000053872    UP000252040    UP000007267    UP000007754    UP000008227   

PRIDE

H9JJI8    H9JJI9    Q96IZ2    Q8C138    F1RV85   

Pfam

PF04750   Far-17a_AIG1

Interpro

IPR006838   Far-17a_AIG1       

ProteinModelPortal

H9JJI8   H9JJI9   A0A2A4ISD3   S4P4C5   A0A194R0B8   A0A194PSZ5   + More
A0A212F7H0   A0A2H1WGM3   A0A2A4ITZ9   A0A194PTA5   I4DJC6   A0A194R142   A0A1E1W9D6   A0A2H1WWJ5   A0A2A4J503   T1IBD8   A0A0D9R570   A0A2D4I7W0   A0A2K6D6X9   A0A2D4GB73   A0A2K6D6W2   A0A2J7PDG0   A0A2K5MJD1   A0A096NKY2   A0A2K5MJC9   A0A2K5JJ01   A0A2I3N3A2   G3WW37   A0A2K6KYY2   A0A2K6RGG7   A0A2K5MJC8   A0A2K5WPU0   A0A1D5Q198   H9EXV2   G7P4F3   M3XJ79   A0A2J8WN06   F7FVQ1   A0A2I3ML13   G7MQK8   H2PHY1   H9GE02   A0A2R9ASQ7   A0A2I3RF37   A0A2K5Y9N0   Q96IZ2   A0A2R9AV55   G3S0A2   Q96IZ2-3   G3R864   A0A1B6DTE3   F7DN37   F7EH87   A0A2K6KZ03   A0A1U7TW54   A0A2K5CIT5   A0A2I3HSN3   M3WAX6   A0A2Y9FZ49   Q60534   A0A195BSL9   A0A195D3P2   A0A151XB65   A0A2D0SL66   Q8C138   G3T4W4   A0A2K5RAU8   A0A2D0SL67   A0A1B6CZW9   A0A0R4J0W3   A0A2I0MXL7   A0A023EZS5   A0A171B0S5   A0A341D0B8   K7FA11   A0A091R2W3   H0Z5X2   F1RV85  

KEGG

101745637    no KO assigned | (RefSeq) androgen-dependent TFPI-regulating protein-like

GO

GO:0016021   GO:0050709   GO:0016787   GO:0042758   GO:0043491   GO:0140052   GO:0010628   GO:0071383   GO:2000402   GO:0002042   GO:1903038   GO:0001934   GO:0009986   GO:0005901   GO:0030195   GO:0003332   GO:0016020   GO:0002686   GO:0005886   GO:0060218   GO:0060216   GO:0016831   GO:0003824   GO:0019752   GO:0030170   GO:0004675   GO:0006559   GO:0004887  

PANTHER

PTHR10989  

Subcellular location

Cell membrane  

Length:

254

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

108.08508

Exp number, first 60 AAs:

21.10736

Total prob of N-in:

0.07792

POSSIBLE N-term signal

sequence

outside

1  -  40

TMhelix

41  -  63

inside

64  -  81

TMhelix

82  -  104

outside

105  -  118

TMhelix

119  -  141

inside

142  -  152

TMhelix

153  -  172

outside

173  -  186

TMhelix

187  -  206

inside

207  -  254

 

 

Pi

214.88153

Theta

156.164502

Tajima's D

0.957294

CLR

0

CSRT

0.647717614119294

Interpretation

Uncertain