SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO00826
Pre Gene Modal
BGIBMGA009690
Annotation
PREDICTED:_androgen-dependent_TFPI-regulating_protein-like_[Bombyx_mori]
Full name
Androgen-dependent TFPI-regulating protein      
Location in the cell
PlasmaMembrane   Reliability : 4.69
 

Sequence

CDS
ATGAGCTATCAAATTTACTTTCGCTTGCTCGGCTATGTGTCGACAATAGCGATGCATATCGGTAATCTAATTTACATGCGGCATACCATACTATCGGCTAATATCAGCGAAAAATCCCTGGATAATGTCGGAATAGGCACTTTCAAGAAAATGGAGTATCGATATTTTACTACTTGGACGGTGGGTCTACAGATAGGATATGCGGCGCTGGGTACACTCTGCGATCTTCTGGTGCTACTAAATAAACACAAAAAGAACTACAGATTACCTAAATATTTGGGCTCGTCGCGGGAAATTATGTTCGCTGGTCTGGTATGGCCGTCTACTTGGGTAGTCTTCACTGTATTTTGGACTTTATTCAACTACGACAGAAGCCTGATATTCCCGGCTTACTTGGACAAGATCGTGACGCGTCTGTCTAACCACGTCATACATACAATGATCGTTCCGGTCGTGGTCTGGGAGGTGATGTTTCGGCCAAGGAAACCAAAAAGTCACTACAGGAACATCGCGCAACTGGCGATACACATGTTGGCGTACGTCTTCGTGTTACATTTCACTTATCACGAGCACGGCGTCTGGCTGTACCCGATCTTCAAAGCAGTTCAAGGAACGATACATTTCTATCTGCTCCACTTTTATGTCGCAGTTATGTGCTTGATGTTCTACTGGCTTCAATGGCGGTTGAACTCTTTGATCCACGGCGTCGAAGACGTAAAGAAGATTCACTGA
Protein
MSYQIYFRLLGYVSTIAMHIGNLIYMRHTILSANISEKSLDNVGIGTFKKMEYRYFTTWTVGLQIGYAALGTLCDLLVLLNKHKKNYRLPKYLGSSREIMFAGLVWPSTWVVFTVFWTLFNYDRSLIFPAYLDKIVTRLSNHVIHTMIVPVVVWEVMFRPRKPKSHYRNIAQLAIHMLAYVFVLHFTYHEHGVWLYPIFKAVQGTIHFYLLHFYVAVMCLMFYWLQWRLNSLIHGVEDVKKIH

Summary

Description
Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro).
Similarity
Belongs to the AIG1 family.
Keywords
Alternative splicing   Cell membrane   Complete proteome   Membrane   Polymorphism   Reference proteome   Transmembrane   Transmembrane helix  
Feature
chain  Androgen-dependent TFPI-regulating protein
splice variant  In isoform 2.
sequence variant  In dbSNP:rs2076185.
EMBL
BABH01017486    BABH01017487    BABH01017488    GAIX01006034    JAA86526.1    NWSH01008210    + More
PCG62651.1    KQ460890    KPJ10969.1    KQ459593    KPI96546.1    AGBW02009872    OWR49681.1    PCG62652.1    ODYU01008534    SOQ52219.1    KPI96547.1    AK401394    BAM18016.1    KPJ10970.1    NWSH01002754    PCG67571.1    GDQN01007452    JAT83602.1    ODYU01011594    SOQ57431.1    NWSH01001079    PCG72724.1    NWSH01003298    PCG66594.1    NWSH01006591    PCG63347.1    IACK01084098    LAA80299.1    IACJ01112898    LAA57005.1    ACPB03005685    AAWZ02016749    AAWZ02016750    AAWZ02016751    GEDC01008352    JAS28946.1    NDHI03003384    PNJ71145.1    AHZZ02024143    NEVH01026389    PNF14352.1    AQIB01159356    ABGA01392235    ABGA01392236    ABGA01392237    ABGA01392238    ABGA01392239    ABGA01392240    ABGA01392241    ABGA01392242    AJFE02097058    AK313114    AK300919    AL022724    CH471087    BC007011    AACZ04065924    NBAG03000244    PNI62836.1    JU323455    AFE67211.1    JSUE03030254    JSUE03030255    GEDC01024428    GEDC01024128    GEDC01022375    GEDC01018863    GEDC01018435    GEDC01006808    JAS12870.1    JAS13170.1    JAS14923.1    JAS18435.1    JAS18863.1    JAS30490.1    CM001279    EHH52716.1    ADFV01015550    ADFV01015551    ADFV01015552    CM001256    EHH17956.1    CABD030043317    CABD030043318    CABD030043319    AGTP01048485    AGTP01048486    AGTP01048487    AFYH01049129    AFYH01049130    AFYH01049131    AFYH01049132    AEFK01063730    AEFK01063731    AEFK01063732    AEFK01063733    AEFK01063734    AEFK01063735    AQIA01052761    AQIA01052762    FR904873    CDQ73036.1    AEMK02000051    AANG04001101    GAMQ01004936    JAB36915.1    AAGW02052199    AAGW02052200    KPI96716.1    KQ982335    KYQ57538.1    KK853016    KDR12478.1    AZIM01002216    ETE64511.1    PYGN01000274    PSN49552.1   
Pfam
PF04750   Far-17a_AIG1
Interpro
IPR006838   Far-17a_AIG1       

Ontologies

Topology

Subcellular location
Cell membrane  
Length:
243
Number of predicted TMHs:
6
Exp number of AAs in TMHs:
127.87844
Exp number, first 60 AAs:
24.1859
Total prob of N-in:
0.95664
POSSIBLE N-term signal
sequence
inside
1  -  8
TMhelix
9  -  31
outside
32  -  57
TMhelix
58  -  80
inside
81  -  100
TMhelix
101  -  120
outside
121  -  134
TMhelix
135  -  157
inside
158  -  168
TMhelix
169  -  188
outside
189  -  202
TMhelix
203  -  225
inside
226  -  243
 
 

Population Genetic Test Statistics

Pi
225.986555
Theta
143.029386
Tajima's D
1.360296
CLR
0.254041
CSRT
0.748262586870656
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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