Gene

KWMTBOMO00826

Pre Gene Modal

BGIBMGA009690

Annotation

PREDICTED:_androgen-dependent_TFPI-regulating_protein-like_[Bombyx_mori]

Location

Bomo_Chr2(-):3629001-3637706      View in EpiBrowser

Full name

Androgen-dependent TFPI-regulating protein      

Location in the cell

PlasmaMembrane   Reliability : 4.69

CDS

ATGAGCTATCAAATTTACTTTCGCTTGCTCGGCTATGTGTCGACAATAGCGATGCATATCGGTAATCTAATTTACATGCGGCATACCATACTATCGGCTAATATCAGCGAAAAATCCCTGGATAATGTCGGAATAGGCACTTTCAAGAAAATGGAGTATCGATATTTTACTACTTGGACGGTGGGTCTACAGATAGGATATGCGGCGCTGGGTACACTCTGCGATCTTCTGGTGCTACTAAATAAACACAAAAAGAACTACAGATTACCTAAATATTTGGGCTCGTCGCGGGAAATTATGTTCGCTGGTCTGGTATGGCCGTCTACTTGGGTAGTCTTCACTGTATTTTGGACTTTATTCAACTACGACAGAAGCCTGATATTCCCGGCTTACTTGGACAAGATCGTGACGCGTCTGTCTAACCACGTCATACATACAATGATCGTTCCGGTCGTGGTCTGGGAGGTGATGTTTCGGCCAAGGAAACCAAAAAGTCACTACAGGAACATCGCGCAACTGGCGATACACATGTTGGCGTACGTCTTCGTGTTACATTTCACTTATCACGAGCACGGCGTCTGGCTGTACCCGATCTTCAAAGCAGTTCAAGGAACGATACATTTCTATCTGCTCCACTTTTATGTCGCAGTTATGTGCTTGATGTTCTACTGGCTTCAATGGCGGTTGAACTCTTTGATCCACGGCGTCGAAGACGTAAAGAAGATTCACTGA

Protein

MSYQIYFRLLGYVSTIAMHIGNLIYMRHTILSANISEKSLDNVGIGTFKKMEYRYFTTWTVGLQIGYAALGTLCDLLVLLNKHKKNYRLPKYLGSSREIMFAGLVWPSTWVVFTVFWTLFNYDRSLIFPAYLDKIVTRLSNHVIHTMIVPVVVWEVMFRPRKPKSHYRNIAQLAIHMLAYVFVLHFTYHEHGVWLYPIFKAVQGTIHFYLLHFYVAVMCLMFYWLQWRLNSLIHGVEDVKKIH

Description

Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro).

Similarity

Belongs to the AIG1 family.

Keywords

Alternative splicing   Cell membrane   Complete proteome   Membrane   Polymorphism   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Androgen-dependent TFPI-regulating protein
splice variant  In isoform 2.
sequence variant  In dbSNP:rs2076185.

Uniprot

H9JJI9   H9JJI8   S4P4C5   A0A2A4ISD3   A0A194R0B8   A0A194PSZ5   + More
A0A212F7H0   A0A2A4ITZ9   A0A2H1WGM3   A0A194PTA5   I4DJC6   A0A194R142   A0A2A4J6I9   A0A1E1W9D6   A0A2H1WWJ5   A0A2A4JMB5   A0A2A4J503   A0A2A4ITN6   A0A2D4I7W0   A0A2D4GB73   T1IBD8   H9GE02   A0A1B6DTE3   A0A2K6D6X9   A0A2K6D6W2   A0A2J8WN06   A0A2I3N3A2   A0A2J7PDG0   A0A0D9R570   A0A2K5MJC8   A0A096NKY2   A0A2K5MJC9   H2PHY1   A0A2R9AV55   Q96IZ2   A0A2R9ASQ7   A0A2I3RF37   Q96IZ2-3   H9EXV2   A0A1D5Q198   A0A1B6CZW9   F7FVQ1   A0A341D0B8   G7P4F3   A0A2I3HSN3   G7MQK8   A0A2K6D6W5   G3S0A2   G3R864   A0A2K5JJ01   A0A2I3ML13   A0A2K6KYY2   A0A2K6RGG7   I3NHT6   A0A2K5MJD1   A0A2U4C5S4   M3XJ79   G3WW37   F7HLH0   A0A2K5WPU0   F6TKL5   A0A1S3MCH5   A0A060X0N9   F1RV85   M3WAX6   A0A2K5Y9N0   A0A1U7TW54   A0A2K5Y9N2   A0A2D0SL67   A0A2K5CIT5   A0A2K5WPV3   F7DN37   G1SDH9   A0A194PTG9   F7EH87   A0A2D0SL66   A0A151XB65   A0A067QU27   V8NRF1   A0A2K5JIW7   A0A2P8YZ85   A0A2K5RAU8   A0A2K6RGJ0   A0A2K6KZ03   F7I3Z6  

Pubmed

19121390    23622113    26354079    22118469    22651552    21881562    + More
22722832    14702039    14574404    15489334    21868574    16136131    25319552    17431167    22002653    22398555    25362486    9215903    21709235    19892987    24755649    17975172    25243066    21993624    24845553    24297900    29403074   

EMBL

BABH01017486    BABH01017487    BABH01017488    GAIX01006034    JAA86526.1    NWSH01008210    + More
PCG62651.1    KQ460890    KPJ10969.1    KQ459593    KPI96546.1    AGBW02009872    OWR49681.1    PCG62652.1    ODYU01008534    SOQ52219.1    KPI96547.1    AK401394    BAM18016.1    KPJ10970.1    NWSH01002754    PCG67571.1    GDQN01007452    JAT83602.1    ODYU01011594    SOQ57431.1    NWSH01001079    PCG72724.1    NWSH01003298    PCG66594.1    NWSH01006591    PCG63347.1    IACK01084098    LAA80299.1    IACJ01112898    LAA57005.1    ACPB03005685    AAWZ02016749    AAWZ02016750    AAWZ02016751    GEDC01008352    JAS28946.1    NDHI03003384    PNJ71145.1    AHZZ02024143    NEVH01026389    PNF14352.1    AQIB01159356    ABGA01392235    ABGA01392236    ABGA01392237    ABGA01392238    ABGA01392239    ABGA01392240    ABGA01392241    ABGA01392242    AJFE02097058    AK313114    AK300919    AL022724    CH471087    BC007011    AACZ04065924    NBAG03000244    PNI62836.1    JU323455    AFE67211.1    JSUE03030254    JSUE03030255    GEDC01024428    GEDC01024128    GEDC01022375    GEDC01018863    GEDC01018435    GEDC01006808    JAS12870.1    JAS13170.1    JAS14923.1    JAS18435.1    JAS18863.1    JAS30490.1    CM001279    EHH52716.1    ADFV01015550    ADFV01015551    ADFV01015552    CM001256    EHH17956.1    CABD030043317    CABD030043318    CABD030043319    AGTP01048485    AGTP01048486    AGTP01048487    AFYH01049129    AFYH01049130    AFYH01049131    AFYH01049132    AEFK01063730    AEFK01063731    AEFK01063732    AEFK01063733    AEFK01063734    AEFK01063735    AQIA01052761    AQIA01052762    FR904873    CDQ73036.1    AEMK02000051    AANG04001101    GAMQ01004936    JAB36915.1    AAGW02052199    AAGW02052200    KPI96716.1    KQ982335    KYQ57538.1    KK853016    KDR12478.1    AZIM01002216    ETE64511.1    PYGN01000274    PSN49552.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000015103    + More
UP000001646    UP000233120    UP000028761    UP000235965    UP000029965    UP000233060    UP000001595    UP000240080    UP000005640    UP000002277    UP000006718    UP000252040    UP000009130    UP000001073    UP000001519    UP000233080    UP000233180    UP000233200    UP000005215    UP000245320    UP000008672    UP000007648    UP000233100    UP000002281    UP000087266    UP000193380    UP000008227    UP000011712    UP000233140    UP000189704    UP000221080    UP000233020    UP000001811    UP000008225    UP000075809    UP000027135    UP000245037    UP000233040   

PRIDE

H9JJI9    H9JJI8    Q96IZ2    F1RV85   

Pfam

PF04750   Far-17a_AIG1

Interpro

IPR006838   Far-17a_AIG1       

ProteinModelPortal

H9JJI9   H9JJI8   S4P4C5   A0A2A4ISD3   A0A194R0B8   A0A194PSZ5   + More
A0A212F7H0   A0A2A4ITZ9   A0A2H1WGM3   A0A194PTA5   I4DJC6   A0A194R142   A0A2A4J6I9   A0A1E1W9D6   A0A2H1WWJ5   A0A2A4JMB5   A0A2A4J503   A0A2A4ITN6   A0A2D4I7W0   A0A2D4GB73   T1IBD8   H9GE02   A0A1B6DTE3   A0A2K6D6X9   A0A2K6D6W2   A0A2J8WN06   A0A2I3N3A2   A0A2J7PDG0   A0A0D9R570   A0A2K5MJC8   A0A096NKY2   A0A2K5MJC9   H2PHY1   A0A2R9AV55   Q96IZ2   A0A2R9ASQ7   A0A2I3RF37   Q96IZ2-3   H9EXV2   A0A1D5Q198   A0A1B6CZW9   F7FVQ1   A0A341D0B8   G7P4F3   A0A2I3HSN3   G7MQK8   A0A2K6D6W5   G3S0A2   G3R864   A0A2K5JJ01   A0A2I3ML13   A0A2K6KYY2   A0A2K6RGG7   I3NHT6   A0A2K5MJD1   A0A2U4C5S4   M3XJ79   G3WW37   F7HLH0   A0A2K5WPU0   F6TKL5   A0A1S3MCH5   A0A060X0N9   F1RV85   M3WAX6   A0A2K5Y9N0   A0A1U7TW54   A0A2K5Y9N2   A0A2D0SL67   A0A2K5CIT5   A0A2K5WPV3   F7DN37   G1SDH9   A0A194PTG9   F7EH87   A0A2D0SL66   A0A151XB65   A0A067QU27   V8NRF1   A0A2K5JIW7   A0A2P8YZ85   A0A2K5RAU8   A0A2K6RGJ0   A0A2K6KZ03   F7I3Z6  

KEGG

101745264    no KO assigned | (RefSeq) androgen-dependent TFPI-regulating protein-like

GO

GO:0016021   GO:0002042   GO:1903038   GO:0001934   GO:0009986   GO:0030195   GO:0005901   GO:0003332   GO:0050709   GO:0016787   GO:0042758   GO:0140052   GO:0043491   GO:0010628   GO:0071383   GO:2000402   GO:0016020   GO:0002686   GO:0060218   GO:0060216   GO:0016831   GO:0003824   GO:0019752   GO:0030170   GO:0004675   GO:0006559   GO:0004887  

PANTHER

PTHR10989  

Subcellular location

Cell membrane  

Length:

243

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

127.87844

Exp number, first 60 AAs:

24.1859

Total prob of N-in:

0.95664

POSSIBLE N-term signal

sequence

inside

1  -  8

TMhelix

9  -  31

outside

32  -  57

TMhelix

58  -  80

inside

81  -  100

TMhelix

101  -  120

outside

121  -  134

TMhelix

135  -  157

inside

158  -  168

TMhelix

169  -  188

outside

189  -  202

TMhelix

203  -  225

inside

226  -  243

 

 

Pi

225.986555

Theta

143.029386

Tajima's D

1.360296

CLR

0.254041

CSRT

0.748262586870656

Interpretation

Uncertain