SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO00799
Pre Gene Modal
BGIBMGA009697
Annotation
PREDICTED:_probable_serine/threonine-protein_kinase_DDB_G0278901_[Bombyx_mori]
Full name
Receptor protein serine/threonine kinase       + More
Serine/threonine-protein kinase receptor      
Location in the cell
Nuclear   Reliability : 3.448
 

Sequence

CDS
ATGCAGAATGTGTTCCACAGTGCTACCCTGTCTTACGATGATGACACGAACGCTCAAACTATGACAGTGAATGATGTTTATAGAGAGAGGCCAATAACAGATATGAAACTTGAAACCGGTGAAACAGTAAGAGTTGAACACTGTACACATACACGAGATGTTTGCTACACATTCTGGCATATGCAGGATCAAGGAAATATTACAATACTTGGACAAGGTTGCTGGAGATCAGCTGAAACAGCAAGGGGCATTAGCACATGTGACAAGTGCATGCGTGCCCCCAAACGATTGCCGGGTTCTAAATTCTGCTGTTGTACCAAAAGTTATTGCAACAGTGATTTCTTATCACTCAAAGAGGAGACGGTGACGATATCTGCCGAGTCTACAATGAACACAGCATCTCAGCAGCCGAGCTATTCCAGCCTCGTCGCTTCGTCATCCCTAGCCCTAGTCGCGATACTTGTGATGGCGATAGTCGTTAAGACGTTTTATTGCAAACGCATCAACATCGATAAGGGGGAGCTTAGTGACGGAACTGATGTCGAGAAAGGTGATATAATGGGCAACTGCCCCGATTCGCTGTCCACGGGACTACTGTGTGTCGACAATCTGACGCTTATCGAACATATAGGTCAAGGTAAATTCGGTTCAGTGTGGCGCGGTTCATTGGGCTCGACGCCAGTTGCTGTCAAACTGTATTCCAGCTCTAGCGCCTGGCAGAAGGAGACGGCTATATACGCGTTACCTCACCTGTCTCATCCAAATCTACTCAGATATTACGGCAGCGAAACAAGACCCACTCTGACTGAGGGTGGCGGGAGGGAACATCTAGTCGTTCTAGAGCTTTGTGTGGGAACTTTGAGGGCGAAGCTTCAGGCTCAGACGTTAAGCTGGTTGGAGTTCGCTACTCTGGCTCACGGGATAGCCGCCGCACTGGCACACCTACATACACCAATCGGGAACAAACCTTGCGTGGTCCATCGCGACGTGAACAGCAACAACGTGCTCATAGCGAGCAACGGCACCGCCAGACTCGCCGACCTGGGTCTGGCCCAAGTCTTGCAGCCCAGGAGAGAGCACACAGCTCCAAACAGGATCACTGAGGCCGGTACCCTTCGATATCTCGCGCCCGAAGCCCTAGAAGGCGCGCTGGACCTCAGCGGAGCCCGGGCGGCCTTGTGCGCCGTCGACGTGTACGCCCTCGGGCTCGTCCTCTGGGAGCTGCTGTGGAGAACCGCCCCGGCCCACAGCGGGCCCACGCCCTGCTACATGCTGCCCTACCAGCATCTGGGGCTGCCGGCCAATCCCACGCTGCATCACATGCAGACGCTGGTGTCCCGCAAGAAGGCCCGGCCTCCGGTGCCGCGCGGGCCGGGGCTCGCGCAGTGCACGGCCGCCGACACGTGCGACGAGTGCTGCGACCACGATGCGGAGGCCAGGTTGACCGCGGTGTGCGTTGAGGAACGCATGGCCGAACTGAAGCAGATACTGCAAGCCCAGGGACCTCTGATACACGATAACAACTTGCATCCGAATTCGGAGACGAGCCCGCCCTCGCCAGCCGATCAGGACAAGAACTCCAACTGCACGGCGTTACGTCACGGTTGTGACGTCACGACCCCGCTGCTCTACCCGCACCCGCACATGGGCCGCAACGCGTGCATCGAACGCAACACGCACACGAGCACGCAGCAATACGTGACGCTCATACACAAGAGCCTGAAGGACATATCCGACCCGAGCGACGCCATCCGACTCGAGAACATAGACGACAATTGCTTGTCTGTGGCCAGGGGCTCGCCCAGGGTTGCCGTACCGGAAAATTCGGGGCCGAACGTGACCAGGTCACACCAGCGCCCGCTAGATTACGTTCAGAACGACGTGAGCCACCACGACGTCGACCGGGGACCGAAGCAAACCAATTTACTGCAGGAGACAAGAACCGAGAAAACCGGATGGGGCATCAGGAAGTTCTTCGAGAAGTTCAACAAGAACAAAATGGATACGGAAGTGAAGCTCGCACCGGAAGGCCAGAGAACGAGGATATCCGTAGTTAACGACAAGAACAACTACAACAGACCCAGCAACTTGGTCCTGAGCCAAGACCCGAATCTTATATACGAAGCGCCCTGCCTCTCGCCGCCAAATCGAACCCTGTCCCCTAACATGATGGCGGACGCGACCTTCAAGGAGATACCCTCGCACAACGACAGTCATATTTACGCGGTCATCGTGCCGAAAGTCCAACCGGACGTAAGCGGTATCAAGAGCAAGAACGGTAGCAGTTCGGAGAGTTTGAAACAGTCCGTAGGCACATCCGCCTCATCCCAGAGCGTTTACAGGAACAACTCTGAATCCGGGGATTGGACGCTCAAGAATCGACTGAGCCGCGACAACAAGCCCGGCTCTAACAGCTCATCCAGGGCCAGTATCAATTTGGAGTTGCAGTTCATAGAGGGTGCGAACCCTGCGGCCAGTCCCTTCGAGTTGAACTCGGATTGTTCTGGAAGTGAAGACGAGCAGCTGCTGCTTTTGTCCGAGAACGGGGGCTCGAGGATCACGATGCAGACGGTCAGCAAAGACCCCAAGTACCAGAACGACGTGCTGAAGGAGAGCCAAAAGAAAACGGTGACCTTCAACAAGAACCACAACCGCTACTCGAACTTCGACAACGAGGTCAGCGACCCCAACGATAAAGAGAATGTAGCGAATGGCTACAGCGGAGACAACCCCGCCTACCTGCCCGCCCCCCCCAACGCCGCCGCCCCCGCGCCCCGCAAGCCCACCGTGCGCCGCCAGCGCTCGCTCGAGCAGGTAAGCGACATCTTCAGCACGGTGAGCGACGTTAAACTAGTGAAGCCGGCGGGCCGGGTCAAGACCCCCGGCGACCTTCCCGTGGCCCTGCGCAAGGCCAGGCGCGACCGAGCCCTTCAGAAGGGCCGGGAGAGCGCCAACAGACTGAGCCTGTACGACGACAGCGTCATGCTGGGGAACACCCTGTAG
Protein
MQNVFHSATLSYDDDTNAQTMTVNDVYRERPITDMKLETGETVRVEHCTHTRDVCYTFWHMQDQGNITILGQGCWRSAETARGISTCDKCMRAPKRLPGSKFCCCTKSYCNSDFLSLKEETVTISAESTMNTASQQPSYSSLVASSSLALVAILVMAIVVKTFYCKRINIDKGELSDGTDVEKGDIMGNCPDSLSTGLLCVDNLTLIEHIGQGKFGSVWRGSLGSTPVAVKLYSSSSAWQKETAIYALPHLSHPNLLRYYGSETRPTLTEGGGREHLVVLELCVGTLRAKLQAQTLSWLEFATLAHGIAAALAHLHTPIGNKPCVVHRDVNSNNVLIASNGTARLADLGLAQVLQPRREHTAPNRITEAGTLRYLAPEALEGALDLSGARAALCAVDVYALGLVLWELLWRTAPAHSGPTPCYMLPYQHLGLPANPTLHHMQTLVSRKKARPPVPRGPGLAQCTAADTCDECCDHDAEARLTAVCVEERMAELKQILQAQGPLIHDNNLHPNSETSPPSPADQDKNSNCTALRHGCDVTTPLLYPHPHMGRNACIERNTHTSTQQYVTLIHKSLKDISDPSDAIRLENIDDNCLSVARGSPRVAVPENSGPNVTRSHQRPLDYVQNDVSHHDVDRGPKQTNLLQETRTEKTGWGIRKFFEKFNKNKMDTEVKLAPEGQRTRISVVNDKNNYNRPSNLVLSQDPNLIYEAPCLSPPNRTLSPNMMADATFKEIPSHNDSHIYAVIVPKVQPDVSGIKSKNGSSSESLKQSVGTSASSQSVYRNNSESGDWTLKNRLSRDNKPGSNSSSRASINLELQFIEGANPAASPFELNSDCSGSEDEQLLLLSENGGSRITMQTVSKDPKYQNDVLKESQKKTVTFNKNHNRYSNFDNEVSDPNDKENVANGYSGDNPAYLPAPPNAAAPAPRKPTVRRQRSLEQVSDIFSTVSDVKLVKPAGRVKTPGDLPVALRKARRDRALQKGRESANRLSLYDDSVMLGNTL

Summary

Catalytic Activity
[receptor-protein]-L-serine + ATP = [receptor-protein]-O-phospho-L-serine + ADP + H(+)
[receptor-protein]-L-threonine + ATP = [receptor-protein]-O-phospho-L-threonine + ADP + H(+)
Similarity
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Feature
chain  Serine/threonine-protein kinase receptor
EC Number
2.7.11.30
Pfam
PF00069   Pkinase        + More
PF01064   Activin_recp
PF07714   Pkinase_Tyr
Interpro
IPR000333   TGFB_receptor        + More
IPR011009   Kinase-like_dom_sf       
IPR000719   Prot_kinase_dom       
IPR017441   Protein_kinase_ATP_BS       
IPR000472   Activin_recp       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
SUPFAM
SSF56112   SSF56112       
PDB
3G2F     E-value=2.6802e-42,     Score=437

Ontologies

Topology

Subcellular location
Membrane  
Length:
1000
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
21.5822
Exp number, first 60 AAs:
4e-05
Total prob of N-in:
0.86123
inside
1  -  137
TMhelix
138  -  160
outside
161  -  1000
 
 

Population Genetic Test Statistics

Pi
215.095891
Theta
159.511598
Tajima's D
1.807283
CLR
0.077367
CSRT
0.846157692115394
Interpretation
Uncertain
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