Gene

KWMTBOMO00794  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009698

Annotation

nascent_polypeptide_associated_complex_protein_alpha_subunit_[Bombyx_mori]

Location

Bomo_Chr2(-):3076139-3081444      View in EpiBrowser

Full name

Nascent polypeptide-associated complex subunit alpha      

Alternative Name

Alpha-NAC

Location in the cell

Nuclear   Reliability : 2.781

CDS

ATGCCAGAACTGACTGAACTTGACAAGGCCACCGCCTCTATGACCGAGAAGCGCAAAGAAGAGACTGCATCATCTGACAGTGACTCTGATGACAACATTCCAGAATTGGAAGATGCAGGTGCACCAGATGCAGGTGGAATCACAAACCCGATTGCTGGAATTGACATCGTCAGCAAATCGAAACAGTCTCGTGGTGAGAAGAAGGCCAGAAAGATAATGAGTAAACTCGGTCTCAAACCAGTACAAGGAGTAGAGAGAGTGACAATCAGAAAATCAAAGAACATTCTCTTTGTCATTAACTCACCTGATGTATACAAGAATCCTCATTCAGACACCTACATTGTTTTTGGTGAAGCCAAGATTGAAGATTTGTCCACACAGGCCACCATGGCTGCAGCAGAGAGATTCAAGGCACCAGAGACCACAGCCACTGGCAATGACGCTTCCACAACTGGAACGACGGTAGCACCAATAGCAGAAGAAGAAGACGAAGAAGGAGTAGACGAGACTGGAGTTGATGAGAAGGACGTGGAGATAGTAATGTCCCAGGCGAACGTCTCTCGAGCGAAAGCAGTCCGAGCGCTCAAGAACAACCAATCTGACATTGTTAATGCAATTATGGAGCTAACAATGTAG

Protein

MPELTELDKATASMTEKRKEETASSDSDSDDNIPELEDAGAPDAGGITNPIAGIDIVSKSKQSRGEKKARKIMSKLGLKPVQGVERVTIRKSKNILFVINSPDVYKNPHSDTYIVFGEAKIEDLSTQATMAAAERFKAPETTATGNDASTTGTTVAPIAEEEDEEGVDETGVDEKDVEIVMSQANVSRAKAVRALKNNQSDIVNAIMELTM

Description

May promote appropriate targeting of ribosome-nascent polypeptide complexes (By similarity). Required for correct localization of the osk/oskar protein to the posterior pole during embryonic development. The osk protein directs the recruitment of molecules responsible for posterior body patterning and germline formation in the embryo.

Subunit

Part of the nascent polypeptide-associated complex (NAC), consisting of Nac-alpha and bicaudal (bic).

Similarity

Belongs to the NAC-alpha family.

Keywords

Complete proteome   Developmental protein   Protein transport   Reference proteome   Transport  

Feature

chain  Nascent polypeptide-associated complex subunit alpha

Uniprot

Q1HQ81   H9JJJ7   I4DM86   S4PXV7   I4DJC7   A0A3G1T1N9   + More
A0A194PU75   A0A194QZI5   A0A212EPN1   A0A1E1W5T5   A0A2H1W3F3   A0A2A4JKN3   A0A2A4ITE7   A0A0K8SSP9   U5EY60   A0A2J7PIS3   A0A1B0CFB5   A0A1L8DIG5   A0A2P8Z4P5   A0A067R157   A0A182N7J5   A0A182V6U9   A0A182L439   A0A182X236   Q7QIB6   A0A182I697   A0A182TN59   A0A182Q980   A0A182PEY4   A0A182WI71   W5JMC0   D6WPS6   A0A1B0DC96   A0A182SGC8   A0A182MJC5   A0A182R9A2   A0A182JDB5   A0A1B6CX80   A0A1B6F758   A0A0K8TP91   A0A1B6EMY6   A0A1B6JWY8   A0A182YJI8   T1DPL2   A0A2M4BZE0   A0A182FI20   A0A1B6I2A0   A0A2M4CND2   A0A2M4A1H2   A0A2M3YZE8   A0A2M3YZH0   E1ZW25   A0A1B6MNW2   V5GCS8   A0A1B6KZF3   E0VJX8   A0A1Q3F7P7   B0WPI0   B4N5Z7   E2BHN8   A0A084WLB0   J3JZJ4   Q16PA5   T1E2Y6   A0A023EJZ8   A0A0J7KZL2   A0A2A3ENP9   V9IJ73   A0A088AUC4   K7IP87   A0A1W4X952   A0A1J1J2V8   A0A0P6IM55   A0A154PG98   A0A0M4E422   A0A0T6B796   B3MG13   A0A1I8PKR6   A0A0P8XP67   F4W5K2   A0A1Y1KA77   B4MDU7   Q0IEK4   A0A1L8EEL8   A0A151X349   A0A0L0C5N2   A0A151JQV6   A0A195D413   A0A1B0BXB1   D3TPE3   A0A1A9XPK0   A0A1A9X4R8   B4P4Y8   A0A0A1WFP3   A0A3B0JSI7   T1PB50   A0A1B0AB83   A0A0B4LEY6   Q94518   B4KQ03  

Pubmed

19121390    22651552    23622113    26354079    22118469    29403074    + More
24845553    20966253    12364791    14747013    17210077    20920257    23761445    18362917    19820115    26369729    25244985    20798317    20566863    17994087    24438588    22516182    23537049    17510324    24330624    24945155    26483478    20075255    18057021    21719571    28004739    26108605    20353571    17550304    25830018    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    10071211    11102369    12537569    15239960   

EMBL

DQ443171    ABF51260.1    BABH01017422    AK402404    BAM19026.1    GAIX01004368    + More
JAA88192.1    AK401395    BAM18017.1    MG992444    AXY94882.1    KQ459593    KPI96528.1    KQ460890    KPJ10953.1    AGBW02013449    OWR43417.1    GDQN01008719    JAT82335.1    ODYU01006085    SOQ47620.1    NWSH01001257    PCG71960.1    NWSH01008684    PCG62452.1    GBRD01009625    JAG56199.1    GANO01000507    JAB59364.1    NEVH01024966    PNF16240.1    AJWK01009907    GFDF01007927    JAV06157.1    PYGN01000196    PSN51463.1    KK869083    KDR11265.1    AAAB01008807    EAA04708.2    APCN01003599    AXCN02000576    ADMH02000632    ETN65522.1    KQ971354    EFA06181.1    AJVK01030690    AXCM01006814    GEDC01019270    JAS18028.1    GECZ01023732    GECZ01013407    JAS46037.1    JAS56362.1    GDAI01001439    JAI16164.1    GECZ01030513    JAS39256.1    GECU01004303    JAT03404.1    GAMD01003254    JAA98336.1    GGFJ01009309    MBW58450.1    GECU01026648    JAS81058.1    GGFL01002523    MBW66701.1    GGFK01001249    MBW34570.1    GGFM01000882    MBW21633.1    GGFM01000895    MBW21646.1    GL434758    EFN74612.1    GEBQ01002347    JAT37630.1    GALX01000541    JAB67925.1    GEBQ01023155    JAT16822.1    DS235231    EEB13684.1    GFDL01011478    JAV23567.1    DS232024    EDS32368.1    CH964154    EDW79786.1    GL448322    EFN84786.1    ATLV01024210    KE525350    KFB51004.1    APGK01034946    BT128676    KB740923    KB631963    AEE63633.1    ENN78092.1    ERL87496.1    CH477789    EAT36197.1    GALA01000865    JAA93987.1    JXUM01078212    JXUM01078213    JXUM01078214    GAPW01004178    KQ563051    JAC09420.1    KXJ74566.1    LBMM01001759    KMQ95806.1    KZ288205    PBC33134.1    JR047348    AEY60389.1    CVRI01000067    CRL06703.1    GDIQ01003438    JAN91299.1    KQ434899    KZC10885.1    CP012524    ALC40691.1    LJIG01009364    KRT83228.1    CH902619    EDV36708.1    KPU76374.1    KPU76375.1    GL887655    EGI70499.1    GEZM01087975    JAV58363.1    CH940662    EDW58712.1    CH477600    EAT38459.1    GFDG01001632    JAV17167.1    KQ982562    KYQ54813.1    JRES01000960    KNC26734.1    KQ978642    KYN29500.1    KQ976881    KYN07586.1    JXJN01022150    EZ423295    ADD19571.1    CM000158    EDW90709.1    KRJ99384.1    GBXI01017059    JAC97232.1    OUUW01000001    SPP74058.1    KA645375    AFP60004.1    AE013599    AHN56161.1    Y08969    AF017783    AY075332    CH933808    EDW08105.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000218220    UP000235965    + More
UP000092461    UP000245037    UP000027135    UP000075884    UP000075903    UP000075882    UP000076407    UP000007062    UP000075840    UP000075902    UP000075886    UP000075885    UP000075920    UP000000673    UP000007266    UP000092462    UP000075901    UP000075883    UP000075900    UP000075880    UP000076408    UP000069272    UP000000311    UP000009046    UP000002320    UP000007798    UP000008237    UP000030765    UP000019118    UP000030742    UP000008820    UP000069940    UP000249989    UP000036403    UP000242457    UP000005203    UP000002358    UP000192223    UP000183832    UP000076502    UP000092553    UP000007801    UP000095300    UP000007755    UP000008792    UP000075809    UP000037069    UP000078492    UP000078542    UP000092460    UP000092443    UP000091820    UP000002282    UP000268350    UP000095301    UP000092445    UP000000803    UP000009192   

PRIDE

Q1HQ81    H9JJJ7    Q94518   

Pfam

PF01849   NAC

Interpro

IPR002715   Nas_poly-pep-assoc_cplx_dom        + More
IPR038187   NAC_A/B_dom_sf       
IPR016641   EGD2/NACA       

Gene 3D

2.20.70.30    

ProteinModelPortal

Q1HQ81   H9JJJ7   I4DM86   S4PXV7   I4DJC7   A0A3G1T1N9   + More
A0A194PU75   A0A194QZI5   A0A212EPN1   A0A1E1W5T5   A0A2H1W3F3   A0A2A4JKN3   A0A2A4ITE7   A0A0K8SSP9   U5EY60   A0A2J7PIS3   A0A1B0CFB5   A0A1L8DIG5   A0A2P8Z4P5   A0A067R157   A0A182N7J5   A0A182V6U9   A0A182L439   A0A182X236   Q7QIB6   A0A182I697   A0A182TN59   A0A182Q980   A0A182PEY4   A0A182WI71   W5JMC0   D6WPS6   A0A1B0DC96   A0A182SGC8   A0A182MJC5   A0A182R9A2   A0A182JDB5   A0A1B6CX80   A0A1B6F758   A0A0K8TP91   A0A1B6EMY6   A0A1B6JWY8   A0A182YJI8   T1DPL2   A0A2M4BZE0   A0A182FI20   A0A1B6I2A0   A0A2M4CND2   A0A2M4A1H2   A0A2M3YZE8   A0A2M3YZH0   E1ZW25   A0A1B6MNW2   V5GCS8   A0A1B6KZF3   E0VJX8   A0A1Q3F7P7   B0WPI0   B4N5Z7   E2BHN8   A0A084WLB0   J3JZJ4   Q16PA5   T1E2Y6   A0A023EJZ8   A0A0J7KZL2   A0A2A3ENP9   V9IJ73   A0A088AUC4   K7IP87   A0A1W4X952   A0A1J1J2V8   A0A0P6IM55   A0A154PG98   A0A0M4E422   A0A0T6B796   B3MG13   A0A1I8PKR6   A0A0P8XP67   F4W5K2   A0A1Y1KA77   B4MDU7   Q0IEK4   A0A1L8EEL8   A0A151X349   A0A0L0C5N2   A0A151JQV6   A0A195D413   A0A1B0BXB1   D3TPE3   A0A1A9XPK0   A0A1A9X4R8   B4P4Y8   A0A0A1WFP3   A0A3B0JSI7   T1PB50   A0A1B0AB83   A0A0B4LEY6   Q94518   B4KQ03  

PDB

3MCE     E-value=2.68184e-16,     Score=205

KEGG

732899    K03626 nascent polypeptide-associated complex subunit alpha | (RefSeq) nascent polypeptide associate

GO

GO:0005854   GO:0005388   GO:0015031   GO:0007275  

PANTHER

PTHR21713  

Length:

211

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00061

Exp number, first 60 AAs:

0.00061

Total prob of N-in:

0.03773

outside

1  -  211

 

 

Pi

329.954209

Theta

203.607086

Tajima's D

1.602194

CLR

0.008404

CSRT

0.815509224538773

Interpretation

Uncertain