Gene

KWMTBOMO00751

Pre Gene Modal

BGIBMGA013339

Annotation

ornithine_decarboxylase_antizyme_[Bombyx_mori]

Location

Bomo_Chr2(-):2426132-2444065      View in EpiBrowser

Full name

Ornithine decarboxylase antizyme 1       + More
Ornithine decarboxylase antizyme      

Alternative Name

ODC antizyme, short form

Location in the cell

Extracellular   Reliability : 1.481 Nuclear   Reliability : 1.193

CDS

ATGATGTACCTCCGCGTGCCCGGGGTCCTGCAGTCCGGCAGCAAGGACAGCTTCATGCTGCTCCTGGATTTCGCTGAAGAGCGTCTCGGCTGTAAGAGTTGCATCATCTGCGTTTTGAAGAGTCGTCCCGACCGCGCTACCCTGCTGCGCACCTTCATGTTCATGGGATTCCAAGTTCTGGCTCCGAATTCGCCGCTGACCCCACAGCACATCAACAACCCTAATTACATTTTCTTACACTACAATATGCAGTAA

Protein

MMYLRVPGVLQSGSKDSFMLLLDFAEERLGCKSCIICVLKSRPDRATLLRTFMFMGFQVLAPNSPLTPQHINNPNYIFLHYNMQ

Description

Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

Subunit

Interacts with ODC1 and thereby sterically blocks ODC homodimerization.

Similarity

Belongs to the CD36 family.
Belongs to the ODC antizyme family.

Keywords

Complete proteome   Polyamine biosynthesis   Reference proteome   Ribosomal frameshifting  

Feature

chain  Ornithine decarboxylase antizyme 1

Uniprot

H9JUX6   Q9GSV9   A0A0K2S3N3   A0A3B0EV17   A0A194PU31   A0A2H1V4P6   + More
A0A2W1BGI7   A0A194R4U9   A0A2A4K061   A0A2A4K0I7   A0A2A4JZ44   A0A0K8S867   A0A212EXT8   A0A2Z6FLD0   A0A1J1HNH0   A0A1J1HSZ5   C3ZX52   A0A1L8E2N1   A0A1B0D1T9   A0A1S4H3Y5   A0A182HQX2   A0A182WXJ2   A0A3N0Y3N8   A0A1B0CKD8   A0A023END3   A0A182FN08   Q9YI98   A0A384BH35   A0A182IYX0   A0A1S4H3U0   A0A2U9C3B0   A0A182VDG5   A0A084VWW2   A0A182KJD5   R7VI46   L5MIF9   A0A1A8ILR5   A0A1A7ZE21   A0A1A8P1A4   A0A1A8LJH8   A0A1A8BPB1   A0A1A8HF04   A0A182UK52   A0A2M3YXK9   A0A2M4A0U7   Q95P51   A0A182K677   A0A3B5AME1   L5ME86   A0A182T4N3   A0A023EMB1   A0A1A8VF33   A0A1A7X5P3   A0A182Q4G2   A0A182YQV2   A0A182MIK8   A0A1A8QA68   A7RKX2   A0A2M4CKR8   A0A1W7R8J5   H0YPX3   A0A3B5AL80   A0A3M0JJ38   W5JQA2   A0A3B4GGH8   A0A3P8QW86   A0A3P9BF37   T1DRW6   A0A146NQN9   A0A315VNU8   Q6X3F2   S7MG55   A0A182PTL5   A0A2P4SQL1   A5JST0   I3MZW7   A0A3B3X8E6   A0A2G9Q4H0   I3JAY0   Q5TNW3   A0A0Q3QYA8   A0A096MH89   K1RDR6   A0A3B3W2J2   L5L6I4   A0A2V2PAT3   F6VR40   A0A1Y9GH65   A0A3B4YLY6   A0A3B4TML7   A0A2I4AX82   A0A3P8SAR7   M7AKR9   A0A182NNN8   A0A060XBG3   A0A3B3X8B0   A0A226M745   A0A151NGV5   A0A182W8E2   A0A3B4Y7C9  

Pubmed

19121390    26354079    28756777    22118469    18563158    12364791    + More
24945155    10600644    24438588    20966253    23254933    14513362    17510324    25244985    17615350    20360741    20920257    23761445    25186727    29703783    22992520    23258410    17495919    23624526    24755649    24621616    22293439   

EMBL

BABH01041439    BABH01041440    AF291575    AAG16235.1    AB999997    BAS21455.1    + More
RBVL01000177    RKO11078.1    KQ459593    KPI96483.1    ODYU01000657    SOQ35811.1    KZ150197    PZC72317.1    KQ460890    KPJ10891.1    NWSH01000338    PCG77284.1    PCG77283.1    PCG77285.1    GBRD01016353    JAG49473.1    AGBW02011708    OWR46254.1    LC384840    BBE28983.1    CVRI01000013    CRK89599.1    CRK89598.1    GG666708    EEN42881.1    GFDF01001107    JAV12977.1    AJVK01010393    AJVK01010394    AAAB01008980    APCN01001608    RJVU01053127    ROL40797.1    AJWK01016088    AJWK01016089    AJWK01016090    GAPW01003183    JAC10415.1    AB017117    CP026254    AWP11104.1    ATLV01017759    KE525185    KFB42456.1    AMQN01003837    KB292015    ELU18279.1    KB100339    ELK37503.1    HAED01011810    SBQ98204.1    HADY01002582    SBP41067.1    HAEI01001181    SBR75043.1    HAEF01007104    HAEG01007493    SBR44486.1    HADZ01004752    HAEA01013847    SBP68693.1    HAEB01008266    HAEC01013048    SBQ81265.1    GGFM01000249    MBW21000.1    GGFK01001082    MBW34403.1    AF396870    AF396871    AY064120    AY133346    CH477314    KB101390    ELK36647.1    GAPW01004154    JAC09444.1    HAEJ01018024    SBS58481.1    HADW01011835    HADX01005021    SBP13235.1    AXCN02001967    AXCM01005077    HAEH01010580    SBR90079.1    DS469517    EDO47835.1    GGFL01001657    MBW65835.1    GEHC01000164    JAV47481.1    ABQF01047514    QRBI01000142    RMC00829.1    ADMH02000643    ETN65468.1    GAMD01000460    JAB01131.1    GCES01152570    JAQ33752.1    NHOQ01001926    PWA20921.1    AY257551    AAP82032.1    KE161324    EPQ03134.1    PPHD01028928    POI26404.1    EF564268    ABQ51195.1    AGTP01068775    AGTP01068776    KZ369196    PIO10445.1    AERX01026419    EAL39277.1    LMAW01002688    KQK78097.1    AYCK01018215    JH818863    EKC32251.1    KB030265    ELK19339.1    QGNU01000250    PWS23116.1    KB586660    EMP25741.1    FR905190    CDQ76978.1    AWGT02031212    OXB51070.1    AKHW03003034    KYO36018.1   

Proteomes

UP000005204    UP000276569    UP000053268    UP000053240    UP000218220    UP000007151    + More
UP000183832    UP000001554    UP000092462    UP000075840    UP000076407    UP000092461    UP000069272    UP000000437    UP000075880    UP000246464    UP000075903    UP000030765    UP000075882    UP000014760    UP000075902    UP000008820    UP000075881    UP000261400    UP000075901    UP000075886    UP000076408    UP000075883    UP000001593    UP000007754    UP000269221    UP000000673    UP000261460    UP000265100    UP000265160    UP000075885    UP000005215    UP000261480    UP000005207    UP000007062    UP000051836    UP000028760    UP000005408    UP000261500    UP000010552    UP000245538    UP000002280    UP000261360    UP000261420    UP000192220    UP000265080    UP000031443    UP000075884    UP000193380    UP000198419    UP000050525    UP000075920   

PRIDE

H9JUX6    Q9GSV9    Q9YI98   

Pfam

PF02100   ODC_AZ        + More
PF01130   CD36
PF00339   Arrestin_N
PF02752   Arrestin_C

Interpro

IPR002993   ODC_AZ        + More
IPR016181   Acyl_CoA_acyltransferase       
IPR038581   ODC_AZ_sf       
IPR029914   ODC-AZ_1       
IPR002159   CD36_fam       
IPR014752   Arrestin_C       
IPR011021   Arrestin-like_N       
IPR014753   Arrestin_N       
IPR017864   Arrestin_CS       
IPR011022   Arrestin_C-like       
IPR014756   Ig_E-set       

SUPFAM

SSF55729   SSF55729        + More
SSF81296   SSF81296       

Gene 3D

3.40.630.60     2.60.40.640     2.60.40.840    

ProteinModelPortal

H9JUX6   Q9GSV9   A0A0K2S3N3   A0A3B0EV17   A0A194PU31   A0A2H1V4P6   + More
A0A2W1BGI7   A0A194R4U9   A0A2A4K061   A0A2A4K0I7   A0A2A4JZ44   A0A0K8S867   A0A212EXT8   A0A2Z6FLD0   A0A1J1HNH0   A0A1J1HSZ5   C3ZX52   A0A1L8E2N1   A0A1B0D1T9   A0A1S4H3Y5   A0A182HQX2   A0A182WXJ2   A0A3N0Y3N8   A0A1B0CKD8   A0A023END3   A0A182FN08   Q9YI98   A0A384BH35   A0A182IYX0   A0A1S4H3U0   A0A2U9C3B0   A0A182VDG5   A0A084VWW2   A0A182KJD5   R7VI46   L5MIF9   A0A1A8ILR5   A0A1A7ZE21   A0A1A8P1A4   A0A1A8LJH8   A0A1A8BPB1   A0A1A8HF04   A0A182UK52   A0A2M3YXK9   A0A2M4A0U7   Q95P51   A0A182K677   A0A3B5AME1   L5ME86   A0A182T4N3   A0A023EMB1   A0A1A8VF33   A0A1A7X5P3   A0A182Q4G2   A0A182YQV2   A0A182MIK8   A0A1A8QA68   A7RKX2   A0A2M4CKR8   A0A1W7R8J5   H0YPX3   A0A3B5AL80   A0A3M0JJ38   W5JQA2   A0A3B4GGH8   A0A3P8QW86   A0A3P9BF37   T1DRW6   A0A146NQN9   A0A315VNU8   Q6X3F2   S7MG55   A0A182PTL5   A0A2P4SQL1   A5JST0   I3MZW7   A0A3B3X8E6   A0A2G9Q4H0   I3JAY0   Q5TNW3   A0A0Q3QYA8   A0A096MH89   K1RDR6   A0A3B3W2J2   L5L6I4   A0A2V2PAT3   F6VR40   A0A1Y9GH65   A0A3B4YLY6   A0A3B4TML7   A0A2I4AX82   A0A3P8SAR7   M7AKR9   A0A182NNN8   A0A060XBG3   A0A3B3X8B0   A0A226M745   A0A151NGV5   A0A182W8E2   A0A3B4Y7C9  

PDB

4ZGY     E-value=3.47862e-16,     Score=200

KEGG

692580    K16548 ornithine decarboxylase antizyme 1 | (RefSeq) Oaz; ornithine decarboxylase antizyme

GO

GO:0008073   GO:0045732   GO:0005634   GO:0005737   GO:0016021   GO:0007165   GO:0090316   GO:0006596   GO:0005829   GO:0006595   GO:1902268   GO:0006545   GO:0009165   GO:0050661   GO:0005524   GO:0006418   GO:0006559   GO:0004887  

PANTHER

PTHR10279   PTHR10279:SF8   PTHR11923  

Length:

84

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.30803

Exp number, first 60 AAs:

0.20338

Total prob of N-in:

0.13963

outside

1  -  84

 

 

Pi

186.87404

Theta

146.302445

Tajima's D

1.082416

CLR

0.155133

CSRT

0.678866056697165

Interpretation

Uncertain