Gene

KWMTBOMO00722  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003259

Annotation

methionine--tRNA_ligase?_cytoplasmic_[Bombyx_mori]

Location

Bomo_Chr2(-):1472574-1501475      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.921

CDS

ATGAAGATATACACAAACAAAAACAATACTGGAACGTTAAAACTGTTAATAGCGGCTAATTTAGCAGCAAAGAAAGTAGAAATTGTGGAAGCCGAGTTTGAAGACGATGTATTCGCAGGGCCCCGTCAGCTGCCGCTCCTCGAGGTCGACCCAGAACTAAGGTTCTTTTCCAGCAATGCGGCGGTCCAGTATCTGTTCCCGATTCTGGACATGTCCGAGAATGGGCAATGTCAGCAGCTTCAAGAATGGGAGGCGACACGCCTTCAGCCGTCCCTAAGTGCTGCGCTCGGGAAATCCCCAGCTTCTGATGTAAAGCAAGTCTTGAAGTCGTCGCTTGAACACGTCAATGGACTGCTGGGAGGACACCAATACGTTCTCGGGGACAAAATCTCAGCGGCCGACATCTCAATATGGAGCACGTTATATCCTCTTACTCACAATGATGATCTCCGAGAACAGTATCTGAAGGAGCTCGGTAATATAAGGCGTTGGTCTGACGCTATTGGAGGTGCGAAATCTGTTCAAGAAGCTGTGAGACAATGGGGCGGCTCACCGACTGGACCATTCGGGCAGATATCTGCCCTGGGCTTACCACAGGTGGCCAACCTCGTCTCTCCTGCAGGGTCGCCGGATGACGACGCCGAGGTCCAAGAAGGTCCGACCCCTGAAGAGATCGAAGCGGCAAAAGAGGGATGGCTCAATGGTCTGAGCAAGCTGCAGCCTCCGTTGAAACAGGAGAAGATTGTGTTACCAGTGAAGGGTCGTAAGAACGTACTGATCACCTCGGCGTTGCCCTATGTCAACAACGTTCCCCACCTCGGCAATATCATCGGATGCGTTCTATCCGCGGACATATTTGCAAGATATTGTCGGTTATGTGATTACAACACGCTGTATATATGCGGCACAGATGAATACGGAACCGCTACGGAGACTAAAGCGCTAGAAGAAGGCGTCACGCCCAAACAGATCTGCGACAAATATTTCGAGATACACAATAATGTCTACCGCTGGTTCAACATTGGATTCGATTATTTCGGGAGAACCTCCACAGAGGAACAGGCTGAGATCACCCAGAGGCTGTTTCTGAAGCTGAACGAGAACGGCTTCGTCAGCTCGCAGACCGTCGACCAGCTGTTCTGCGAGAAGTGCGACAGGTTTCTGGCTGACAGGTTCGTGGAGGGGACGTGCCCACATCCCGGCTGCGGGTACGAGGGCGCGCGCGGCGACCAGTGCGACAAGTGCGGGAGGCTGGTCAACGCGCCCGAGCTGCTGCAGCCGAGGTGTAAGGTCTGCGCCCACCCCCCCGTCCTCAAGCCCAGCGAGCAACTCTTCATCGAACTAGGGCAGTTGGAGCCGTCGCTGCGCAGCTGGATGTCGCGGTGGGAGCACCTTTGGTCGGCCCCCGCGCGCGCCGTGGGCCGCGCCTGGCTGCGGGAGCCGCTGCGGGCGCGCGCCCTCACCCGCGACCTGCGCTGGGGGGTGCCCGTGCCGCTCGACGGGTACCGACACAAGGTCTTCTACGTGTGGTTCGACGCTCCCATCGGCTACATGAGCATCACCCAGTGCGCCACGAAGCAATACGAGGCCTGGTGGAAACCTGACAAGGAATATGACGTCAGTTTATATCAGTTCATGGCGAAGGACAACGTGCCTTTCCACGTGGTCATGTTCCCGGCGACCGTCCTGGGCGTCAATGAGGGCCACCTGCTGGTCAAGCACCTGTTCGCCACCGAATACTTGAACTACGAAGAAGGGAAGTTTTCTAAGTCGAGAGGCGTCGGTGTGTTTGGCAACGACGCGCAAGACACCGGGATACCGTCGGACGTGTGGCGCTTCTACCTGGCCAGCATCCGACCCGAGACCTCGGACTCCAGCTTCAGCTGGACCGAACTGGGCACCAGGAACAACTCGGAGCTTTTGAACAACCTGGGAAACTTTTGTCACCGTTCGTTGAGCTTCTGTTCGAACGCGTTCAAGGGTCTCATCCCGGAACCGAACCCGCGACGTTCGGACTACGAGCTGATGGCGCTCGTCAACAGGGAGATAGCAGCGTACGTGCAGAACATGGAGAAGGGTCGTCTGCGTGAGGCCTTGAGGCACGTGCTGTCCATCTCTAGGCTCGGCAACCAGCACATGCAGTCGGAGCAACCCTGGGTGCTGCTCAAAGGAAGCGAGGATGATAAGCAAAGGGGTGCAACAGCCATCGGTCTGTGTTGCCAGCTCGTGGCGCTGCTGTGCGCGCTGCTGGCGCCCTACGTGCCGGACACGACGCGCAAGCTCCGCGGACAACTCAACGTGGACGCCGAAAAGCTCCGACTGAACCCCGAGAACCCCAGGCTCCTCCGGTACCTGCCGCCGGGTCACATCATCGGGAAACCGGAGCCCTTATTCGTGAAGATCGAGCAGGAGAGGCTCGAGGAGCTGAGGGCGAGGTACGCCGGCACGCAGAGCCAGAGGGCAGATAAGAAAAACTCCAAAACGTTGGATATAGCTGAATTAGAGAAGGCAATAGCTGAGCAGGGCGATGCAGTTAGAAAATTGAAGTCGACAACGAAAGATAAGTCAGTATGGCAACCGGAGGTTGAGAAGCTGTTAGAGCTGAAGAAACGGCTCACCGAAGCTCAGAAGCAAGCTGAAACGCGACCAGCAGCGAACCAGGCCGCTGGCGATGTGGCCAGCTTAGAGAAAGCTATTGCTGAGCAGGGCGATGCAGTTAGAAAATTGAAATCGACAACGAAAGATAAGTCAGTTTGGCAACCGGAGGTTGAGAAGCTGTTAGAGCTGAAGAAACGGCTCACCGAAGCTCAGAAGCAAGCTGAAACGCGACCAGCAGCGAACCAGGCCGCTGGCGATGTGGCCAGCTTAGAGAAAGCTATTGCTGAGCAGGGTGACAAAGTCCGGAAATTGAAAGCCTCAACAAAAGACAAGGCCGTGTGGCAGCCTGAAGTAAATGTATTGCTCGATCTGAAAAAACGTCTCCAAGCACTGCAAGTCAAGAAATAA

Protein

MKIYTNKNNTGTLKLLIAANLAAKKVEIVEAEFEDDVFAGPRQLPLLEVDPELRFFSSNAAVQYLFPILDMSENGQCQQLQEWEATRLQPSLSAALGKSPASDVKQVLKSSLEHVNGLLGGHQYVLGDKISAADISIWSTLYPLTHNDDLREQYLKELGNIRRWSDAIGGAKSVQEAVRQWGGSPTGPFGQISALGLPQVANLVSPAGSPDDDAEVQEGPTPEEIEAAKEGWLNGLSKLQPPLKQEKIVLPVKGRKNVLITSALPYVNNVPHLGNIIGCVLSADIFARYCRLCDYNTLYICGTDEYGTATETKALEEGVTPKQICDKYFEIHNNVYRWFNIGFDYFGRTSTEEQAEITQRLFLKLNENGFVSSQTVDQLFCEKCDRFLADRFVEGTCPHPGCGYEGARGDQCDKCGRLVNAPELLQPRCKVCAHPPVLKPSEQLFIELGQLEPSLRSWMSRWEHLWSAPARAVGRAWLREPLRARALTRDLRWGVPVPLDGYRHKVFYVWFDAPIGYMSITQCATKQYEAWWKPDKEYDVSLYQFMAKDNVPFHVVMFPATVLGVNEGHLLVKHLFATEYLNYEEGKFSKSRGVGVFGNDAQDTGIPSDVWRFYLASIRPETSDSSFSWTELGTRNNSELLNNLGNFCHRSLSFCSNAFKGLIPEPNPRRSDYELMALVNREIAAYVQNMEKGRLREALRHVLSISRLGNQHMQSEQPWVLLKGSEDDKQRGATAIGLCCQLVALLCALLAPYVPDTTRKLRGQLNVDAEKLRLNPENPRLLRYLPPGHIIGKPEPLFVKIEQERLEELRARYAGTQSQRADKKNSKTLDIAELEKAIAEQGDAVRKLKSTTKDKSVWQPEVEKLLELKKRLTEAQKQAETRPAANQAAGDVASLEKAIAEQGDAVRKLKSTTKDKSVWQPEVEKLLELKKRLTEAQKQAETRPAANQAAGDVASLEKAIAEQGDKVRKLKASTKDKAVWQPEVNVLLDLKKRLQALQVKK

Similarity

Belongs to the class-I aminoacyl-tRNA synthetase family.

Uniprot

A0A0D6A6H2   H9J172   A0A2A4K7Y8   A0A194PZ78   A0A194R007   S4P722   + More
A0A212F767   A0A1I8M974   A0A0M4E7B7   A0A0L0CCR9   A0A1I8Q5H0   B4MK24   A0A336K3R3   B4PBS9   A1ZBE9   B3NKC5   A0A1W4V6B0   B4HP29   B3MI08   A0A336L480   B4QD42   B4LNG8   A0A0Q9X7H3   A0A0J9RHI7   B4J4J7   Q292H1   B4GDJ5   A0A1W4X8J2   Q8MRS4   B4KMR8   A0A3B0JJQ6   A0A182G347   A0A1Y1N8Z9   Q16FM1   A2I885   A0A1S4G2P1   Q16G77   T1P978   A0A182H5P8   U5EXD0   A0A182V633   Q7Q3I3   A0A182L275   A0A182HVB8   A0A1Q3FWE3   A0A1Q3FWD3   A0A1S4GWK4   A0A182K7M0   A0A182TIA6   A0A182WTC5   K7IZM6   A0A1S4KI36   A0A1A9WPB0   A0A182RBQ6   A0A182PMC7   D6WU61   A0A2M4BC14   A0A0K8VU08   A0A0K8WGM2   A0A182YGX9   A0A182NE71   W5JBE2   A0A182R1F6   A0A2M3YZK8   A0A084VP50   A0A182MEZ9   A0A2M4BC37   A0A2M4A1R9   A0A2M4BCP4   A0A2M3ZFN8   A0A034V2H4   A0A182G0D4   A0A182IYF9   A0A2M4A1L8   A0A0A1WES6   A0A2M4A1G2   W8BPX2   A0A182W9T4   A0A0C9RA76   A0A1A9X9H6   A0A1B0BPP5   A0A1A9UV52   A0A067QZ66   N6TAC6   U4UGW8   A0A088A3B9   A0A1L8DRR1   A0A195E089   A0A151XIW2   A0A195BVL4   A0A158NEP7   A0A0A9XCR8   A0A2J7RLB8   A0A3L8D8R7   A0A026WYY4   F4WRP6   A0A0K8SXF5   A0A0A9X9E8   A0A0K8SXM0   A0A154NYD7  

Pubmed

25644632    19121390    26354079    23622113    22118469    25315136    + More
26108605    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    15632085    18057021    26483478    28004739    17510324    17519023    12364791    20966253    20075255    18362917    19820115    25244985    20920257    23761445    24438588    25348373    25830018    24495485    24845553    23537049    21347285    25401762    30249741    24508170    21719571   

EMBL

LC008193    BAQ58045.1    BABH01031383    BABH01031384    BABH01031385    BABH01031386    + More
NWSH01000062    PCG80048.1    KQ459593    KPI96460.1    KQ460890    KPJ10869.1    GAIX01004784    JAA87776.1    AGBW02009910    OWR49585.1    CP012524    ALC42554.1    JRES01000678    KNC29254.1    CH963846    EDW72463.1    UFQS01000040    UFQT01000040    SSW98198.1    SSX18584.1    CM000158    EDW91563.1    AE013599    AAF57625.2    CH954179    EDV55147.1    CH480816    EDW48531.1    CH902619    EDV38018.1    UFQS01001876    UFQT01001876    SSX12628.1    SSX32071.1    CM000362    EDX07747.1    CH940648    EDW62148.1    CH933808    KRG04283.1    CM002911    KMY94954.1    CH916367    EDW02702.1    CM000071    EAL24891.1    CH479181    EDW31652.1    AY119445    AAM50099.1    EDW08810.2    KRG04282.1    OUUW01000001    SPP73669.1    JXUM01140882    KQ569141    KXJ68752.1    GEZM01011894    JAV93350.1    CH478414    EAT33034.1    EF173375    ABM68611.1    CH478315    EAT33248.1    KA645336    AFP59965.1    JXUM01112327    KQ565582    KXJ70857.1    GANO01001005    JAB58866.1    AAAB01008964    EAA12906.4    APCN01002504    GFDL01003104    JAV31941.1    GFDL01003114    JAV31931.1    KQ971352    EFA06771.1    GGFJ01001448    MBW50589.1    GDHF01009976    JAI42338.1    GDHF01002023    JAI50291.1    ADMH02001962    ETN60175.1    AXCN02000870    GGFM01000920    MBW21671.1    ATLV01014977    KE524999    KFB39744.1    AXCM01000141    GGFJ01001449    MBW50590.1    GGFK01001267    MBW34588.1    GGFJ01001447    MBW50588.1    GGFM01006625    MBW27376.1    GAKP01021470    GAKP01021468    GAKP01021466    GAKP01021464    GAKP01021462    GAKP01021460    GAKP01021458    JAC37486.1    GGFK01001299    MBW34620.1    GBXI01016778    JAC97513.1    GGFK01001268    MBW34589.1    GAMC01015036    JAB91519.1    GBYB01005160    JAG74927.1    JXJN01018147    JXJN01018148    KK852861    KDR14813.1    APGK01045645    KB741037    ENN74688.1    KB632319    ERL92272.1    GFDF01005044    JAV09040.1    KQ979999    KYN18294.1    KQ982080    KYQ60255.1    KQ976401    KYM92310.1    ADTU01013602    GBHO01027016    JAG16588.1    NEVH01002692    PNF41623.1    QOIP01000011    RLU16917.1    KK107078    EZA60354.1    GL888292    EGI63053.1    GBRD01007843    JAG57978.1    GBHO01027015    JAG16589.1    GBRD01007842    JAG57979.1    KQ434772    KZC03890.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000095301    + More
UP000092553    UP000037069    UP000095300    UP000007798    UP000002282    UP000000803    UP000008711    UP000192221    UP000001292    UP000007801    UP000000304    UP000008792    UP000009192    UP000001070    UP000001819    UP000008744    UP000192223    UP000268350    UP000069940    UP000249989    UP000008820    UP000075903    UP000007062    UP000075882    UP000075840    UP000075881    UP000075902    UP000076407    UP000002358    UP000091820    UP000075900    UP000075885    UP000007266    UP000076408    UP000075884    UP000000673    UP000075886    UP000030765    UP000075883    UP000069272    UP000075880    UP000075920    UP000092443    UP000092460    UP000078200    UP000027135    UP000019118    UP000030742    UP000005203    UP000078492    UP000075809    UP000078540    UP000005205    UP000235965    UP000279307    UP000053097    UP000007755    UP000076502   

PRIDE

H9J172    A1ZBE9    Q8MRS4   

Pfam

PF09334   tRNA-synt_1g        + More
PF00458   WHEP-TRS
PF18485   GST_N_5
PF00043   GST_C
PF14497   GST_C_3

Interpro

IPR014758   Met-tRNA_synth        + More
IPR036282   Glutathione-S-Trfase_C_sf       
IPR029038   MetRS_Zn       
IPR033911   MetRS_core       
IPR041598   MARS_N       
IPR015413   Methionyl/Leucyl_tRNA_Synth       
IPR009080   tRNAsynth_Ia_anticodon-bd       
IPR041872   Anticodon_Met       
IPR000738   WHEP-TRS_dom       
IPR009068   S15_NS1_RNA-bd       
IPR014729   Rossmann-like_a/b/a_fold       
IPR001412   aa-tRNA-synth_I_CS       
IPR010987   Glutathione-S-Trfase_C-like       
IPR004045   Glutathione_S-Trfase_N       
IPR023458   Met-tRNA_ligase_1       
IPR004046   GST_C       

SUPFAM

SSF47323   SSF47323        + More
SSF47616   SSF47616       
SSF57770   SSF57770       
SSF47060   SSF47060       

Gene 3D

2.20.28.20     3.40.50.620    

CDD

cd00814  MetRS_core
cd07957  Anticodon_Ia_Met

ProteinModelPortal

A0A0D6A6H2   H9J172   A0A2A4K7Y8   A0A194PZ78   A0A194R007   S4P722   + More
A0A212F767   A0A1I8M974   A0A0M4E7B7   A0A0L0CCR9   A0A1I8Q5H0   B4MK24   A0A336K3R3   B4PBS9   A1ZBE9   B3NKC5   A0A1W4V6B0   B4HP29   B3MI08   A0A336L480   B4QD42   B4LNG8   A0A0Q9X7H3   A0A0J9RHI7   B4J4J7   Q292H1   B4GDJ5   A0A1W4X8J2   Q8MRS4   B4KMR8   A0A3B0JJQ6   A0A182G347   A0A1Y1N8Z9   Q16FM1   A2I885   A0A1S4G2P1   Q16G77   T1P978   A0A182H5P8   U5EXD0   A0A182V633   Q7Q3I3   A0A182L275   A0A182HVB8   A0A1Q3FWE3   A0A1Q3FWD3   A0A1S4GWK4   A0A182K7M0   A0A182TIA6   A0A182WTC5   K7IZM6   A0A1S4KI36   A0A1A9WPB0   A0A182RBQ6   A0A182PMC7   D6WU61   A0A2M4BC14   A0A0K8VU08   A0A0K8WGM2   A0A182YGX9   A0A182NE71   W5JBE2   A0A182R1F6   A0A2M3YZK8   A0A084VP50   A0A182MEZ9   A0A2M4BC37   A0A2M4A1R9   A0A2M4BCP4   A0A2M3ZFN8   A0A034V2H4   A0A182G0D4   A0A182IYF9   A0A2M4A1L8   A0A0A1WES6   A0A2M4A1G2   W8BPX2   A0A182W9T4   A0A0C9RA76   A0A1A9X9H6   A0A1B0BPP5   A0A1A9UV52   A0A067QZ66   N6TAC6   U4UGW8   A0A088A3B9   A0A1L8DRR1   A0A195E089   A0A151XIW2   A0A195BVL4   A0A158NEP7   A0A0A9XCR8   A0A2J7RLB8   A0A3L8D8R7   A0A026WYY4   F4WRP6   A0A0K8SXF5   A0A0A9X9E8   A0A0K8SXM0   A0A154NYD7  

PDB

5GOY     E-value=0,     Score=1771

KEGG

101739633    K01874 methionyl-tRNA synthetase [EC:6.1.1.10] | (RefSeq) BmMRS; methionine--tRNA ligase, cytoplasmi

PATHWAY

00450    Selenocompound metabolism - Bombyx mori (domestic silkworm)
00970    Aminoacyl-tRNA biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0006431   GO:0004825   GO:0017101   GO:0005737   GO:0005829   GO:0016021   GO:0004812   GO:0006412   GO:0000166   GO:0006418   GO:0006559   GO:0004887  

Length:

1001

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.32285

Exp number, first 60 AAs:

0.00349

Total prob of N-in:

0.00953

outside

1  -  1001

 

 

Pi

229.001758

Theta

153.760779

Tajima's D

2.723364

CLR

0.155526

CSRT

0.96335183240838

Interpretation

Uncertain