Gene

KWMTBOMO00715

Pre Gene Modal

BGIBMGA003230

Annotation

RNA-directed_RNA_polymerase_L_[Papilio_machaon]

Location

Bomo_Chr2(+):1160085-1165849      View in EpiBrowser

Full name

Large structural protein      

Alternative Name

RNA-directed RNA polymerase L

Location in the cell

Nuclear   Reliability : 3.626

CDS

ATGATCTCAGATGACTTGCTAATTGAAAAAGAGCTGACCAGTATCAAAACAAACGGAAAATACTTTTTGTTCCCTACTACATTAATTATGTGTGTTCTTGATAACTTGCAGACACGATTCTACATAAGATTACATGTTGCAATTAAAGAACAAAATGAAGGACTAAGAGGTCTTTTAAACCATTATGACCGTCTTCACTCATCATTGGTCTTACTTAGATCTAAGTATAAAAATCACTTCTTTGATATCATGAAGAACTGGGATGCTTACTGTATAGGATGTACAGTGTCAGATGAAGTAGAAGATCTAGGGTTTAAAACATTAAAGGATTCGATAGAGGCAGAGTTGTTCGAAAAATACAATAAACATGATATAAGAGATATATTAGATTTAATGTCCTGTCTTAACATATCAAATAACCGAGATATTGCAGTCCCGATCTCTCTTTACTTCTCAAACTTGAGCAAGAATTATGGTCATCCAATATTACATCCAACTGAAGGGATCGAAAAACTCCGTTTGAACTCTAAAAAACAGATCCCAGTTGATGATAATATAGCGAAGAAAGTTTTGTGGATGTTCAGAAAGACGTACTTTATGAATTACTTTAGGAAGAAAGGGAACTATCCACATCATAAAGTATTAGGAGAACTTCACCCAGTACTAGTTGATTGCTTGAAAGATGAAAGAGTATTAACAGCTAATGAATTAAAATCATTACCTTTATCTGCCTGGGGAAACCTGAAACTGGATAAAAACCATGACATGAGTTTAGAAATAGATGAAAAGGAATTGTTGAAAGATACTGCATGCTCACCCCCAAGAGAAGAATGGTTTCGACCCTATGATCAATGTGCTTTCCAAAATCTTTACAATCAAAGAAAACCTAGGAGTTGGAATGATTTTGAACCTCGAGTGTTATCAAGATACCTCAAGGGTGATGAAGGAGAATTAGCAAGAAAAATAATGGATCAAGAAAATTCATTCTATAATCACTTGCGAGATGATATAGTGCAACTTTGTCGAAAGGAAAGAGAGTTAAACATCAAGGGCAGGGTGTTCTGTAAGCAAACTTACGAGATGAGACTAATGCAAGTTTGTATGGAAAAGTCTCTAAGTGACAATATTCTCCCATATATAAGAGAACAAACTATGACTAATACTGAACTTGAAGTTGCAAAGAGGATGGATAAAGTTGCATCTCATCTCAAAGAAAAAGGTCATGCAAACCTTAATTTAGATCTGAGTTCATGGAATCAACTTAATCGTCATGAATTAAATAAATATTTATTTCAAGAATTGGATGATTTACATGGAAGGAAGAATCTTTATTCTGACTCTCATTTATGGTTTAATCGCTGCATGGTATTGCTTAGTTCTAGATTAACCCCTCCAAAAATAGGACCAGACGGCGAACCATTAGCAGGAGATTATTGCCATTACAACCAGTTTGGAGGATTCGAAGGAATGAGACAAAAAGCGTGGACACTAACAACAATAATGATCATCAAAATTGCGTTAGAAGAATGTAATATCCATGGTGAAGTAATGGGGCAAGGAGATAATCAGATAATCCACATAAGATTGAGTACTGAACAACAGGGCAGACCTCATTTTTATATTAAACTTCTGCTCAATAGCTTGGATTATCTTTTCATATCCGCTGGTCTCTTATTGAAACTCCAGGAAACTTGGTATTCTCAAAATCTGTTTGAGTACTCAAAAGTTAGATATTACAAGTCAATCAGAATCGATGATAGTCTCAAAAGACTCAATAGAATGATACCCGATATAAATGAAGGATTTCCATCTTTACAATCCTTGATTACTGGAGTCTCTACCACAACCGAAAATATGTCCAGAAATTATGTCTCTCCGGTCACACCTTTTTTCCTTTACTCGCTAGAATTAGGTAACACTCTTAAACGGAAAGGTATACTTGATCTTAAGTCCAGAGAGACAGATAAATTATGTGCCCTGATGAATATTCCCTCTATTCTAGGGGGATTACCTCTTTCAAACATGTATCAACATTGTCAGAGAGGATGCCCTGATCCACTAACAATCTGGCTTAAAGTTATTGAGACTATAAGAAAGAATAGTCCTAGAATATATAATCATATATTACACCTCATTCCATGTAATATTAAAGCTACTTATGATCCTGTCAAATTAGTAGAAGATATATACAGTTTGAATATTGTCGGCATGCCAAACTTTGAAAGAAAAGCTCGAGAAATTATCGAAGAATTTCTACCCACCTATGTCACCAACCCTAAAGTTATAAGATTATTAGGTGCAGACCGTTCAGATCTGGAAGCATTATGTAGTATTTTGACTACTATGAGACCATATGTTGCTAATCTGGCACATGAGATTCTAAGAAATTCAAATGAAGGAGTCCAGTTACAGCTAATAGGGAGTTTCTCTAATCTTCAAACAATCAATCGGATGATAAATGAGGATCCAAATAGAACAGAGACGATTTTCTCTTTAGGGAAATTCAAAGATGCTGAGGCCATCGAGGTACTTAAGAAAAGATTGATCAAATCGGAATTACCGGTCAATGGAACCCATCTTTTAGAAAGTGCCCTTTCCTCTATTCCTTGTACTTTTAAAGCTTCACAGTGGCTCAGAGAGACTACCTGGGGATTTCCGATTACTGGGATTACAAGTCCTGTCCCCTGTGAACAGGTTAAAATAGAAGATTATGACACAGCAGAAAAACACCTTAAAAAAGACTGTATAATTGTTAAAACATCTTACAAACTTAAAACTGAAGGGAGAAATGCACTCAAGGTTCGAGGACCATTTGAACCTTATTTGGGCTCATCGACCCCTGAAAAGATGATCAAACCAAAATTGACAGTCGTTAACCCAAATCCTCAAATCAAATCAGTGATGAAACTGTACTATATTCTTACATATTTAGAAAGAATGGATCCTAATAGTGCTCTAATTGGGCTTGTGAATAAAATGATTCAAGAAAAACTTAAATATTTACCCACTGAATTTAGTCAAACTCCTCTCTCAGATTGGTGTGGAAGGAATTACGGCGGGAGTTATGAACACAGGTTTAAAGCTTCTTCCCAGAAAAGGTCTGCTCTTTTCTCATTAATGGAAAACCTTGCAACACATGTCACTATCAATACCAACCTTCTTGGAAAAGCACTCAGAGGAAATGAAGATTACAACCTATTTTTCCAAGAAATTTTTCTTTATATACAAAATTATGTAACTGAATGTGCGAGTAGAGGAATACCTATTGCCGATACATATGCAGTGCCTTTAAATTGTCCGGATTGTACTTATTTAATTCTCAATACACCTATATCAATAAATCTCCAACACATGAGCTACCAATCAAGAATGATTCAAGATCAAGTTAACTCTAAATTAAGTAAAACTAACTTGACAGAAAGTATTCATATTTGCACACTCGCAATGTCTCTATCTGTAGGAAGGAAATTAGCAACTGCACGTCTCCATGACCCAGAAGTTCACAATACATTGGAAACATTTCAAGGGGTCAAGACTGATGAGTCAACAGAAAGAACTAGTAGCAACTTAATGTCAGAATTTCGTAATGCGAACATAGACTATGTCCTGGTTGGAGCATTACAAGGAAGCAAGCAGCTAGTAGAATTTGTAATAGGAAGCTCTAGAGAATATCCTGTCTCGATATTCGAACACTTATCTTACTTAATAATCAACAGTGAGAGAATGCAAGAAATACTTCAACTCCTAGGAGTTCCTATAGAGAAGCACTCCTCAGTGACTCAAACAAGTGGACTAGCAAAGATACTTGCTAAGTCAACTCTAGAGTATATCCGAAATAGAAAAGGAATGTTCTTTAGAGCCTGTGCATTTACCACGTTCTCCTCTGACTTAATTTCTAAACAAGCTTATTTCTGGAGAATCTTTGTAGGACACCTTATCCATGAAGATTCAAGACTAACAACCATCCAAAAAAGAGGGATTATGAGAATTCCTCAATGCGGAGGGTCTAATGTTCACGAATGGAGATCGAAGGTCCCTATAGATCTAACAAAGGGGCTCTCGGTTGAGATTAAATTCGAAGAAACTGATGCAATTTCTGTTTGGCGTGATCTCAAGAGTGAGATAAGTGAACACATAGAGCCTAGGTTTCCCTTATCCAGCCGATTCAACAAAGAGATGGTCAAAGATAATGATTCTCCACAGAGAATCGAGATTAGTGAGCCATTAAACAACTGTTTCCACTTCTCTTTTGACTCCCTGCTAGAACACGGAATGACAGAAAGTCCATTATGGGTAAAGTGGGTTCATCACTGCACCAGACAGGTTGGAAGAATTAGTACTTCAGCATCAAAAATTCATCAAGTAATGAGTTATTATCCAGAAATACTTCCTCAAGAGGGATTGATCATCACACTAGCAGAGGGATCAGGAGGAATCCTCCATTACTTCTCTCACTTGTTCACCACTTCTCATCTGATTTATAATACATTGCAAAGTGACATCGTCGAAAATAAAGAGAATGTACTCAACATAAGTCCTCCAGCATTAGTCGGAGATCAATGTAGTCCTACAGATAGACTATTATACTTAGAGGAAACATGTCTAGGAGAAACTGATATTACAAACAAAGCTTTCATTGAAAAATTCACCACTATAATACGGAGCGAAAATCATGCAATCCTTATTCTCAATATGGATGCAGAACTAAAAACAGATCTGACTAACACCGACAAATTGGATATATACCTTCCTTTAGTTAGAACCTATCTAACACCTGCAAGTTTAATTATAAACAAAATGTTCATCAAATCCCATGACGAGTTAACTCACATAAGATATCGGTGCAAGTCTCTTGGATATCTTTGCGACTTCCACAAACCATCCGCCAGCCATCCTCATAATGATGAGGTCTATGTAGTTTGTTTTCTGGATTTACAGAATAACTACATAGAATCACAAGAACCCATTGGAGAACTTCATTCTTTGAATTGGAAACTAGCACAAAAAAAGATTCAGCTGTTATCAACAAGACCTAACAGGGTAAATTACCTGAAGCACATATTAGGACAGGCCAATGAGAGTCTTCTCAAAAGTGTAAGGAGTCATCCTTGTGTTTGGACAGTCAGGGAGAAATATCAAGTCGAAGAAATTTCAGAACACTTTATTACGAAAAGACATCAAAGGAATTTAATCATGTGTCTTCTCGCAATAGAAAGAAATTCTGAAGTTATAGATTATCATGAAAAGATCATGGTCTATATACCATTTGTTAACAAAGAACAAATAGTATCTCTTCTTGTATTATCTGTACTAACATCACTTTATCGAAATTTTGACCAACTCGTTTCAATCTTGGACTCTCTCTCGATTTTAGAAGTCAAATGTAACATCATACCACCGAAGAAGATCGAAGTGAGCTTAGTTTTGATAACTGGCCCAGAGACTTCATCTCGATCTGTTCTTGGTATCCTAGACCACAAAATGAAAGATTACTTCAGGACTTTGCCGTTCTTCCGCGATCCAGCAAATCCAAGAGTCCCCGCTTATACCTTAAGAGATGGGATTACTAAAATGAGAGAAGCAGAACAAATGAGATATGAAGTTGAGGCAAATCTCAAAGAATTGGTTAGAGAAAGCGAATGTGGATATTCAAGTTACCTTCGAATTCTAAGAAGATAA

Protein

MISDDLLIEKELTSIKTNGKYFLFPTTLIMCVLDNLQTRFYIRLHVAIKEQNEGLRGLLNHYDRLHSSLVLLRSKYKNHFFDIMKNWDAYCIGCTVSDEVEDLGFKTLKDSIEAELFEKYNKHDIRDILDLMSCLNISNNRDIAVPISLYFSNLSKNYGHPILHPTEGIEKLRLNSKKQIPVDDNIAKKVLWMFRKTYFMNYFRKKGNYPHHKVLGELHPVLVDCLKDERVLTANELKSLPLSAWGNLKLDKNHDMSLEIDEKELLKDTACSPPREEWFRPYDQCAFQNLYNQRKPRSWNDFEPRVLSRYLKGDEGELARKIMDQENSFYNHLRDDIVQLCRKERELNIKGRVFCKQTYEMRLMQVCMEKSLSDNILPYIREQTMTNTELEVAKRMDKVASHLKEKGHANLNLDLSSWNQLNRHELNKYLFQELDDLHGRKNLYSDSHLWFNRCMVLLSSRLTPPKIGPDGEPLAGDYCHYNQFGGFEGMRQKAWTLTTIMIIKIALEECNIHGEVMGQGDNQIIHIRLSTEQQGRPHFYIKLLLNSLDYLFISAGLLLKLQETWYSQNLFEYSKVRYYKSIRIDDSLKRLNRMIPDINEGFPSLQSLITGVSTTTENMSRNYVSPVTPFFLYSLELGNTLKRKGILDLKSRETDKLCALMNIPSILGGLPLSNMYQHCQRGCPDPLTIWLKVIETIRKNSPRIYNHILHLIPCNIKATYDPVKLVEDIYSLNIVGMPNFERKAREIIEEFLPTYVTNPKVIRLLGADRSDLEALCSILTTMRPYVANLAHEILRNSNEGVQLQLIGSFSNLQTINRMINEDPNRTETIFSLGKFKDAEAIEVLKKRLIKSELPVNGTHLLESALSSIPCTFKASQWLRETTWGFPITGITSPVPCEQVKIEDYDTAEKHLKKDCIIVKTSYKLKTEGRNALKVRGPFEPYLGSSTPEKMIKPKLTVVNPNPQIKSVMKLYYILTYLERMDPNSALIGLVNKMIQEKLKYLPTEFSQTPLSDWCGRNYGGSYEHRFKASSQKRSALFSLMENLATHVTINTNLLGKALRGNEDYNLFFQEIFLYIQNYVTECASRGIPIADTYAVPLNCPDCTYLILNTPISINLQHMSYQSRMIQDQVNSKLSKTNLTESIHICTLAMSLSVGRKLATARLHDPEVHNTLETFQGVKTDESTERTSSNLMSEFRNANIDYVLVGALQGSKQLVEFVIGSSREYPVSIFEHLSYLIINSERMQEILQLLGVPIEKHSSVTQTSGLAKILAKSTLEYIRNRKGMFFRACAFTTFSSDLISKQAYFWRIFVGHLIHEDSRLTTIQKRGIMRIPQCGGSNVHEWRSKVPIDLTKGLSVEIKFEETDAISVWRDLKSEISEHIEPRFPLSSRFNKEMVKDNDSPQRIEISEPLNNCFHFSFDSLLEHGMTESPLWVKWVHHCTRQVGRISTSASKIHQVMSYYPEILPQEGLIITLAEGSGGILHYFSHLFTTSHLIYNTLQSDIVENKENVLNISPPALVGDQCSPTDRLLYLEETCLGETDITNKAFIEKFTTIIRSENHAILILNMDAELKTDLTNTDKLDIYLPLVRTYLTPASLIINKMFIKSHDELTHIRYRCKSLGYLCDFHKPSASHPHNDEVYVVCFLDLQNNYIESQEPIGELHSLNWKLAQKKIQLLSTRPNRVNYLKHILGQANESLLKSVRSHPCVWTVREKYQVEEISEHFITKRHQRNLIMCLLAIERNSEVIDYHEKIMVYIPFVNKEQIVSLLVLSVLTSLYRNFDQLVSILDSLSILEVKCNIIPPKKIEVSLVLITGPETSSRSVLGILDHKMKDYFRTLPFFRDPANPRVPAYTLRDGITKMREAEQMRYEVEANLKELVRESECGYSSYLRILRR

Catalytic Activity

a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)

Uniprot

A0A191T7V7   A0A0N1PIT2   H9J143   A0A1L3KN31   A0A0B5KK48   A0A140D8N6   + More
A0A1L3KN20   W4VRB8   A0A2Z4HFG9   A0A1Z2RSZ4   A0A1Z2RT94   A0A1Z2RTF5   A0A1Z2RT53   A0A1Z2RSW5   A0A2Z4HFJ1   A0A2Z4HFC6   A0A2Z4HFA6   A0A2Z4HFC4   A0A2Z4HF97   A0A2Z4HFG4   A0A2S1ZPS1   A0A2Z4HFJ7   A0A2Z4HFB8   A0A2Z4HFC7   A0A2Z4GIN2   A0A2Z4HF69   A0A2Z4HF79   A0A2Z4HFS7   A0A2H4YI41   A0A0B5KTS7   A0A1Z2RT41   A0A1Z2RTE0   A0A1Z2RT54   A0A1Z2RSU8   A0A1Z2RTB4   A0A1C9U5D4   A0A1C9U5K0  

Pubmed

27236849    26354079    19121390    27880757    25633976    28637756    + More
29741476    29203920    27639161   

EMBL

KU865643    ANI26478.1    KQ460794    KPJ12187.1    BABH01031416    KX884430    + More
APG78739.1    KM817638    AJG39135.1    KR822819    AMK09260.1    KX884428    APG78729.1    GANO01004103    JAB55768.1    MH430651    AWW13453.1    MF176268    ASA47322.1    MF176318    ASA47413.1    MF176332    MF176377    ASA47433.1    ASA47504.1    MF176298    ASA47379.1    MF176247    ASA47292.1    MH430665    AWW13503.1    MH430657    AWW13485.1    MH430663    MH430664    AWW13497.1    AWW13500.1    MH430666    AWW13507.1    MH430653    AWW13465.1    MH430648    MH430659    AWW13443.1    AWW13492.1    MH237595    AWK27462.1    MH430650    AWW13450.1    MH430654    AWW13472.1    MH430656    AWW13482.1    MH037149    AWW01093.1    MH430655    AWW13479.1    MH430658    AWW13489.1    MH430652    AWW13458.1    MG012486    AUE23903.1    KM817661    AJG39227.1    MF176296    ASA47369.1    MF176375    ASA47494.1    MF176316    ASA47403.1    MF176245    ASA47282.1    MF176356    ASA47464.1    KX148551    AOR51366.1    KX148552    AOR51372.1   

Proteomes

UP000053240    UP000005204    UP000202789    UP000270875    UP000270144    UP000201180    + More
UP000275001    UP000280288    UP000270635    UP000280841    UP000204232    UP000272427    UP000218283    UP000267964   

PRIDE

H9J143   

Pfam

PF14318   Mononeg_mRNAcap        + More
PF00946   Mononeg_RNA_pol
PF01728   FtsJ

Interpro

IPR025786   Mononega_L_MeTrfase        + More
IPR014023   Mononeg_RNA_pol_cat       
IPR016269   RNA-dir_pol_paramyxovirus       
IPR026890   Mononeg_mRNAcap       
IPR002877   rRNA_MeTrfase_FtsJ_dom       

ProteinModelPortal

A0A191T7V7   A0A0N1PIT2   H9J143   A0A1L3KN31   A0A0B5KK48   A0A140D8N6   + More
A0A1L3KN20   W4VRB8   A0A2Z4HFG9   A0A1Z2RSZ4   A0A1Z2RT94   A0A1Z2RTF5   A0A1Z2RT53   A0A1Z2RSW5   A0A2Z4HFJ1   A0A2Z4HFC6   A0A2Z4HFA6   A0A2Z4HFC4   A0A2Z4HF97   A0A2Z4HFG4   A0A2S1ZPS1   A0A2Z4HFJ7   A0A2Z4HFB8   A0A2Z4HFC7   A0A2Z4GIN2   A0A2Z4HF69   A0A2Z4HF79   A0A2Z4HFS7   A0A2H4YI41   A0A0B5KTS7   A0A1Z2RT41   A0A1Z2RTE0   A0A1Z2RT54   A0A1Z2RSU8   A0A1Z2RTB4   A0A1C9U5D4   A0A1C9U5K0  

PDB

5A22     E-value=1.89119e-31,     Score=346

KEGG

NA   

GO

GO:0005524   GO:0003968   GO:0004482   GO:0019012   GO:0016021   GO:0006370   GO:0050661   GO:0006559   GO:0004887   GO:0006139   GO:0016740  

Subcellular location

Virion  

Length:

1892

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.44995

Exp number, first 60 AAs:

1.41042

Total prob of N-in:

0.07270

outside

1  -  1892

 

 

Pi

303.072592

Theta

218.406559

Tajima's D

1.139799

CLR

202.238624

CSRT

0.697165141742913

Interpretation

Uncertain