Gene

KWMTBOMO00687  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003221

Annotation

PREDICTED:_probable_nucleolar_GTP-binding_protein_1_[Bombyx_mori]

Location

Bomo_Chr2(+):520856-532998      View in EpiBrowser

Full name

Nucleolar GTP-binding protein 1      

Alternative Name

Novel nucleolar protein 1

Location in the cell

Mitochondrial   Reliability : 2.195 Nuclear   Reliability : 1.728

CDS

ATGAGTTTGTACAACTTTAAAAAGATTGCTGTAGTCCCTACAGCTAAGGACTTTATAGACATAATTTTATCGAAAACACAAAGGAAAACTCCTACAGTCGTTCACAAGCATTATAAAATATCAAGAATACGTGGGTTTTATATTAGAAAAGTGAAATATACCCAGCAGAACTTCCACGACCGACTGTCCAGAATTATTCAGGAATTCCCAAAGTTAGATGATGTCCATCCATTTTATGCTGATCTCATGAACGTATTGTACGACAAGGATCATTACAAACTTGGACTCGGACAGCTGAATACAGCCAGACATCTTATTGACAATGTCGCAAAAGACTATGTGAGACTGTTAAAATATGGAGATTCGTTGTATCGGTGCAAACAGCTCAAACGTGCGGCTCTGGGTCGCATGGCCACCATCATGAAACGGCAAGGAGCTAATCTTACATACCTGGAACAGGTCCGTCAACATTTAGCACGTTTACCATCGATAGATCCCTACACCAGGACGATAATCATCTGTGGATTCCCAAATGTCGGAAAATCAAGTTTTATTAATAAAATAACACGTGCTGATGTGGAAGTGCAGCCATATGCGTTTACCACAAAGAGTCTGTATGTTGGTCATACTGATTACAAATATTTGAGATGGCAGGTGATAGACACCCCTGGAATCTTGGATCATCCATTGGAAGAACGCAATGTTATAGAAATGCAAGCGGTCACAGCTTTGGCTCATCTCAGAGCTGCCATACTATACTTCATAGATCCGTCTGAGCAGTGTGGCCATAGTATTGAAGACCAGATATCACTGTTCGAAAGTATAAAGCCTTTATTCACAAGCAAACCCCTAATAGTAGTGTTAAACAAGATGGATGTGGTCAAACCTGAAGAGCTGTCTCTGAGTAAGAAACAGTTGCTGGACGATCTGACCGAAACGTGCTCTAAAGGAAATCTTGTCAATGCGGATTCAAATTCTGATCTGTCCGTGGTGCCTGTGATGCGGATGTCCACTGTGACTGAAGAGGGCGTGCAGGAGGTCAAAATTGAAGCCTGCGAGAGGCTGCTGGGACACCGGGTCACAGAGAAAATGCGGACAAAGAAGGTGGACGGCATCTTGAACCGGCTCCACGTGGCGGTGCCGGCCCCGCGCGACGACAAGCCGCGCCCGCCCGTGCTGCCGCCCTCGGTCCTCGCCAAGAAGGAGAAACAAGCAGAGAAGGAGAACCGGAAGAGGAAACTGGAGAGGGACATCGAGGTGGAGCTCGGCGACGACTACGTACTCGACTTGAAGAAGAACTACACGGAGATCCCGGAGGACGAGCGCTATGACGTCATCCCGGAGATCTGGGAGGGACACAACATCGCCGACTATATCGACCCGGACATCTTTGATAAACTGGCAGAGTTGGAGAAGGACGAGGAACTGCGCGAGGCTGGCGGCATGTACGCCGCGCCCAAGATCGAGCTGGACGACACCGTGAGGGAGATCAGGGAACTGGCCCGGCAGATACGCAACAAGAAGGCCATTCTCAAGGACGAGTCTCGCCTGGTGAAGCAGTCCACGAAGCCGGTGATGCCGCGCACCTCGCGAGCCAAGACCAAGCAGAGGTCCACCTCCAAGCTCAGGAAGGACATGGAGAAACTTGGCGTGGACATGTCGGAGACCGGCGACGCGCACTTCACCCGCGCCCGCCCCCGCTCCCGCTCCCGCTCGCTCTCCGCGCCGCCCGCCAAGCGCGCGCGGGAACCCTCCAACCAGCCGGTGGCCGACCCCATCATGCGCGTGAAAGTAAAGAGGATGGCGCACGCGGCCATCGCCAAGAAGACCAAGAAGATGGGCCTCAAGGGAGAGGCGGACCGGTTCATCGGCACCAAGATGCCGAAGCATCTGTTCGCTGGAAAACGTGGGGTCGGCAAGACGGACCGGAGATAG

Protein

MSLYNFKKIAVVPTAKDFIDIILSKTQRKTPTVVHKHYKISRIRGFYIRKVKYTQQNFHDRLSRIIQEFPKLDDVHPFYADLMNVLYDKDHYKLGLGQLNTARHLIDNVAKDYVRLLKYGDSLYRCKQLKRAALGRMATIMKRQGANLTYLEQVRQHLARLPSIDPYTRTIIICGFPNVGKSSFINKITRADVEVQPYAFTTKSLYVGHTDYKYLRWQVIDTPGILDHPLEERNVIEMQAVTALAHLRAAILYFIDPSEQCGHSIEDQISLFESIKPLFTSKPLIVVLNKMDVVKPEELSLSKKQLLDDLTETCSKGNLVNADSNSDLSVVPVMRMSTVTEEGVQEVKIEACERLLGHRVTEKMRTKKVDGILNRLHVAVPAPRDDKPRPPVLPPSVLAKKEKQAEKENRKRKLERDIEVELGDDYVLDLKKNYTEIPEDERYDVIPEIWEGHNIADYIDPDIFDKLAELEKDEELREAGGMYAAPKIELDDTVREIRELARQIRNKKAILKDESRLVKQSTKPVMPRTSRAKTKQRSTSKLRKDMEKLGVDMSETGDAHFTRARPRSRSRSLSAPPAKRAREPSNQPVADPIMRVKVKRMAHAAIAKKTKKMGLKGEADRFIGTKMPKHLFAGKRGVGKTDRR

Description

Involved in the biogenesis of the 60S ribosomal subunit.
Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle (PubMed:24255106). May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs (PubMed:24255106).

Similarity

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.

Keywords

Cell cycle   Cell division   Complete proteome   GTP-binding   Mitosis   Nucleotide-binding   Nucleus   Reference proteome   Ribosome biogenesis  

Feature

chain  Nucleolar GTP-binding protein 1

Uniprot

A0A2W1BSM8   A0A2A4JB68   A0A194PZV5   D6WR57   A0A1Y1L5U0   A0A1W4XGU9   + More
J3JWL5   A0A0K8UAU0   A0A088AUU3   A0A0L7QL59   A0A2J7PD57   A0A0A1X0F2   B4LN40   W8BBX4   A0A034WSY7   A0A0K8TRI1   B4KTH4   A0A1W4UYD6   A0A1L8ED98   A0A1L8EDA9   A0A1I8PMP4   A0A2P8YT71   B4P415   B3N7H3   A0A1L8EDI7   E2BWL7   B4MJN7   A0A0B4LEY9   Q9V411   A0A232EG88   K7J2V8   B4J4E9   T1PGH7   B4QH85   B4HSR8   A0A1B6HJI0   A0A0M4EV72   A0A023FCH1   A0A154PK65   A0A1B0FR70   A0A2A3E7Z3   A0A0J7NHX3   A0A1A9VN72   B4GHS6   A0A1B6L217   Q28ZG8   A0A0C9QUM2   D3TPK2   A0A026W2X2   A0A067QRT9   B3MFK3   A0A310SUI6   A0A3B0JCM0   A0A0V0G4Q4   R4WJM9   A0A069DW17   A0A224XKY7   A0A0P4VM80   A0A0L0CPG3   A0A0K8V0Z4   A0A1B0CKD3   F4WL71   A0A0N0BG08   A0A158NZJ0   E2AQY2   A0A1J1ITM5   A0A1L8DHY1   A0A2S2R2Z9   A0A1S4FNZ2   Q16UL5   A0A182MB80   A0A023EUN8   J9JX20   A0A182WL15   A0A182RMX9   A0A1Q3FWH5   A0A182UQ05   Q7QIT0   A0A182HWF5   A0A2M3YXK1   A0A2M3ZZ51   A0A2M4BGM6   A0A182WWS5   T1DQ49   A0A2M4A161   W5JW60   A0A195CIB3   A0A084WJV0   A0A182SD60   A0A0A9ZEK9   C5WLT8   A0A336JY94   A0A182QK04   A0A195BMS3   A0A182IK65   A0A182NJP6   A0A195FCB0   T1ICJ4   A0A182KD56   A0A182Y270  

Pubmed

28756777    26354079    18362917    19820115    28004739    22516182    + More
25830018    17994087    24495485    25348373    26369729    29403074    17550304    20798317    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    24255106    28648823    20075255    25315136    22936249    25474469    15632085    20353571    24508170    30249741    24845553    23691247    26334808    27129103    26108605    21719571    21347285    17510324    24945155    26483478    12364791    14747013    17210077    20920257    23761445    24438588    25401762    26823975    25244985   

EMBL

KZ149912    PZC78082.1    NWSH01002193    PCG68938.1    KQ459593    KPI96700.1    + More
KQ971354    EFA06007.1    GEZM01063645    JAV69042.1    BT127633    AEE62595.1    GDHF01028580    GDHF01019997    JAI23734.1    JAI32317.1    KQ414934    KOC59347.1    NEVH01026393    PNF14270.1    GBXI01009946    JAD04346.1    CH940648    EDW60044.1    GAMC01007805    JAB98750.1    GAKP01000286    JAC58666.1    GDAI01000860    JAI16743.1    CH933808    EDW08535.1    GFDG01002092    JAV16707.1    GFDG01002091    JAV16708.1    PYGN01000374    PSN47441.1    CM000157    EDW89498.1    CH954177    EDV59378.1    GFDG01002140    JAV16659.1    GL451131    EFN79973.1    CH963846    EDW72326.1    AE013599    AHN56045.1    AF181654    NNAY01004854    OXU17338.1    CH916367    EDW01631.1    KA647245    AFP61874.1    CM000362    CM002911    EDX06339.1    KMY92505.1    CH480816    EDW47095.1    GECU01032850    JAS74856.1    CP012524    ALC41725.1    GBBI01000239    JAC18473.1    KQ434926    KZC11688.1    CCAG010022994    KZ288356    PBC27171.1    LBMM01004791    KMQ92085.1    CH479183    EDW36046.1    GEBQ01022230    JAT17747.1    CM000071    EAL25645.1    GBYB01007454    JAG77221.1    EZ423354    ADD19630.1    KK107488    QOIP01000012    EZA49936.1    RLU15738.1    KK853011    KDR12537.1    CH902619    EDV36688.1    KQ759866    OAD62489.1    OUUW01000001    SPP72960.1    GECL01003102    JAP03022.1    AK417775    BAN20990.1    GBGD01000779    JAC88110.1    GFTR01007623    JAW08803.1    GDKW01000365    JAI56230.1    JRES01000204    KNC33324.1    GDHF01026847    GDHF01020079    JAI25467.1    JAI32235.1    AJWK01016025    GL888207    EGI65034.1    KQ435794    KOX74112.1    ADTU01004645    GL441846    EFN64128.1    CVRI01000059    CRL03074.1    GFDF01008099    JAV05985.1    GGMS01015173    MBY84376.1    CH477618    EAT38228.1    AXCM01002461    JXUM01002670    GAPW01000458    KQ560143    JAC13140.1    KXJ84199.1    ABLF02032387    GFDL01003108    JAV31937.1    AAAB01008807    EAA03933.2    APCN01001489    GGFM01000239    MBW20990.1    GGFK01000513    MBW33834.1    GGFJ01003064    MBW52205.1    GAMD01002764    JAA98826.1    GGFK01001057    MBW34378.1    ADMH02000263    ETN67194.1    KQ977720    KYN00470.1    ATLV01024074    KE525348    KFB50494.1    GBHO01001811    GBHO01001810    GDHC01020762    JAG41793.1    JAG41794.1    JAP97866.1    BT088903    ACT09400.1    UFQS01000016    UFQT01000016    SSW97419.1    SSX17805.1    AXCN02000497    KQ976433    KYM87288.1    KQ981685    KYN38031.1    ACPB03020780   

Proteomes

UP000218220    UP000053268    UP000007266    UP000192223    UP000005203    UP000053825    + More
UP000235965    UP000008792    UP000009192    UP000192221    UP000095300    UP000245037    UP000002282    UP000008711    UP000008237    UP000007798    UP000000803    UP000215335    UP000002358    UP000001070    UP000095301    UP000000304    UP000001292    UP000092553    UP000076502    UP000092444    UP000242457    UP000036403    UP000078200    UP000008744    UP000001819    UP000053097    UP000279307    UP000027135    UP000007801    UP000268350    UP000037069    UP000092461    UP000007755    UP000053105    UP000005205    UP000000311    UP000183832    UP000008820    UP000075883    UP000069940    UP000249989    UP000007819    UP000075920    UP000075900    UP000075903    UP000007062    UP000075840    UP000076407    UP000000673    UP000078542    UP000030765    UP000075901    UP000075886    UP000078540    UP000075880    UP000075884    UP000078541    UP000015103    UP000075881    UP000076408   

PRIDE

Q9V411    C5WLT8   

Pfam

PF08155   NOGCT        + More
PF17835   NOG1_N
PF06858   NOG1
PF00059   Lectin_C
PF00100   Zona_pellucida

Interpro

IPR027417   P-loop_NTPase        + More
IPR006073   GTP_binding_domain       
IPR010674   NOG1_Rossman_fold_dom       
IPR031167   G_OBG       
IPR012973   NOG_C       
IPR041623   NOG1_N       
IPR024926   NOG1       
IPR005225   Small_GTP-bd_dom       
IPR016186   C-type_lectin-like/link_sf       
IPR001304   C-type_lectin-like       
IPR016187   CTDL_fold       
IPR001507   ZP_dom       

SUPFAM

SSF52540   SSF52540        + More
SSF56436   SSF56436       

Gene 3D

3.10.100.10    

ProteinModelPortal

A0A2W1BSM8   A0A2A4JB68   A0A194PZV5   D6WR57   A0A1Y1L5U0   A0A1W4XGU9   + More
J3JWL5   A0A0K8UAU0   A0A088AUU3   A0A0L7QL59   A0A2J7PD57   A0A0A1X0F2   B4LN40   W8BBX4   A0A034WSY7   A0A0K8TRI1   B4KTH4   A0A1W4UYD6   A0A1L8ED98   A0A1L8EDA9   A0A1I8PMP4   A0A2P8YT71   B4P415   B3N7H3   A0A1L8EDI7   E2BWL7   B4MJN7   A0A0B4LEY9   Q9V411   A0A232EG88   K7J2V8   B4J4E9   T1PGH7   B4QH85   B4HSR8   A0A1B6HJI0   A0A0M4EV72   A0A023FCH1   A0A154PK65   A0A1B0FR70   A0A2A3E7Z3   A0A0J7NHX3   A0A1A9VN72   B4GHS6   A0A1B6L217   Q28ZG8   A0A0C9QUM2   D3TPK2   A0A026W2X2   A0A067QRT9   B3MFK3   A0A310SUI6   A0A3B0JCM0   A0A0V0G4Q4   R4WJM9   A0A069DW17   A0A224XKY7   A0A0P4VM80   A0A0L0CPG3   A0A0K8V0Z4   A0A1B0CKD3   F4WL71   A0A0N0BG08   A0A158NZJ0   E2AQY2   A0A1J1ITM5   A0A1L8DHY1   A0A2S2R2Z9   A0A1S4FNZ2   Q16UL5   A0A182MB80   A0A023EUN8   J9JX20   A0A182WL15   A0A182RMX9   A0A1Q3FWH5   A0A182UQ05   Q7QIT0   A0A182HWF5   A0A2M3YXK1   A0A2M3ZZ51   A0A2M4BGM6   A0A182WWS5   T1DQ49   A0A2M4A161   W5JW60   A0A195CIB3   A0A084WJV0   A0A182SD60   A0A0A9ZEK9   C5WLT8   A0A336JY94   A0A182QK04   A0A195BMS3   A0A182IK65   A0A182NJP6   A0A195FCB0   T1ICJ4   A0A182KD56   A0A182Y270  

PDB

6N8L     E-value=1.38559e-142,     Score=1300

KEGG

101741801    K06943 nucleolar GTP-binding protein | (RefSeq) probable nucleolar GTP-binding protein 1

PATHWAY

03008    Ribosome biogenesis in eukaryotes - Bombyx mori (domestic silkworm)

GO

GO:0042254   GO:0005525   GO:0005730   GO:0090307   GO:0005634   GO:0051301   GO:0016021   GO:0006508   GO:0003824   GO:0005667   GO:0005737   GO:0004505   GO:0006559   GO:0004887  

PANTHER

PTHR45759:SF1  

Subcellular location

  

Length:

644

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.000600000000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00086

outside

1  -  644

 

 

Pi

297.678646

Theta

183.645962

Tajima's D

1.882738

CLR

0.005246

CSRT

0.863506824658767

Interpretation

Uncertain