Gene

KWMTBOMO00684  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003219

Annotation

glutamate_decarboxylase_1_[Chilo_suppressalis]

Location

Bomo_Chr2(+):444226-495302      View in EpiBrowser

Full name

Glutamate decarboxylase      

Location in the cell

Cytoplasmic   Reliability : 2.382

CDS

ATGTCAAAACTAACACTGGACGGTTTCTTTTCATACTGCAAGCAAATAGCAGAGCATATACAATTGAGCGAAAGGATGGCTTCGATATCCGGCCAGGGAACTCCTAAGCTGACATCCGCTGTCGGGAACCTGTACTATGACTCCATTCTGCCGTACCGCGAGGATGCCAATATGCAGACCAGGGAGTTCCTCGCCAGGGTGGTGGACGTGCTCCTCGACTTCGTGCAAAAGGTCAACGACAGGAATGAAAAGATCTTGGAGTTCAAGATGCCCGAAGAGATGCAGAAGCTCCTAGACTTGGAGCTGCACGATGAGCCTCTCCCTCTGAAGCAACTCCTCGAAGACTGCAAGGCTACGCTCAAGTACCAAGTCAAAACCGGGCATCCTCACTTCTTCAACCAGCTGTCGTGCGGCCTGGACGTGATATCTCTGGCCGGGGAGTGGCTGACGGCTGCTGCAAACACCAACATGTTCACGTACGAGATAGCCCCGGTCTTCATCTTGATGGAAAACATCGTGCTGGAGAAGATGCGCAACATGATCGGGTGGAAGACTGGCGATTCTATACTGGCACCTGGCGGCTCTGTGTCCAATCTCTACGCTTTCCTGGCTGCTCGTCACCACAAGTTCCCGCAGTACAAAGAGAAGGGTCTCACCAGCATCCCTGGGCACCTAGTCATGTTTACTTCGGACCAGTGTCACTACTCTGTGAAGTCCTGCGCTTCGGTCTGCGGCCTGGGCACAGACTACTGTGTGTGCGTGCCTTCGGACGAACGCGGCAGGATGATACCCGCCCAGCTGGAGCGCCTTGTCCGCTACCACAAGGACAAGGGCCACGTCCCGTTCTTCGTGAACGCCACTTCGGGGACAACGGTGCTCGGCGCCTTCGACCCGCTCAGCGAGATTGCCGACATCTGTGAGAAGTATGACATGTGGATGCACGTGGATGCTGCTTGGGGCGGAGGCCTGCTGTTCTCGAAGAAATACCGTCACCCTCGGCTAACCGGCATCGAGAGGGCTGATTCTGTCACGTGGAACCCTCACAAGCTGATGGGGACTCTGCTTCAGTGCTCCACAGTGCACTTTAAGTATGAAGTAAGTGAAATTGAACACATTCTGACTTGTTGA

Protein

MSKLTLDGFFSYCKQIAEHIQLSERMASISGQGTPKLTSAVGNLYYDSILPYREDANMQTREFLARVVDVLLDFVQKVNDRNEKILEFKMPEEMQKLLDLELHDEPLPLKQLLEDCKATLKYQVKTGHPHFFNQLSCGLDVISLAGEWLTAAANTNMFTYEIAPVFILMENIVLEKMRNMIGWKTGDSILAPGGSVSNLYAFLAARHHKFPQYKEKGLTSIPGHLVMFTSDQCHYSVKSCASVCGLGTDYCVCVPSDERGRMIPAQLERLVRYHKDKGHVPFFVNATSGTTVLGAFDPLSEIADICEKYDMWMHVDAAWGGGLLFSKKYRHPRLTGIERADSVTWNPHKLMGTLLQCSTVHFKYEVSEIEHILTC

Catalytic Activity

H(+) + L-glutamate = 4-aminobutanoate + CO2

Cofactor

pyridoxal 5'-phosphate

Subunit

Homodimer.

Similarity

Belongs to the group II decarboxylase family.

Keywords

Complete proteome   Decarboxylase   Lyase   Neurotransmitter biosynthesis   Pyridoxal phosphate   Reference proteome  

Feature

chain  Glutamate decarboxylase

Uniprot

A0A0G3VI11   A0A0N0PBF8   A0A2A4J514   A0A194PTE4   A0A212FH35   A0A0K8VBT3   + More
A0A034V440   W8B868   A0A1I8PBY7   A0A1I8N673   D6WRJ1   A0A1B6ECJ1   A0A1Y1K1D6   A0A087ZN21   A0A1A9V4B6   A0A1A9ZRZ0   A0A158NCY8   A0A151WYC3   A0A0L7R6C2   A0A232EY01   A0A151JAL0   A0A1B0B7T2   A0A1B6M1D2   A0A1A9YEK3   A0A1B6LN87   A0A195F6W9   A0A0M4EH78   A0A195B879   B4N410   A0A1J1JAW4   A0A2S2P8Z1   A0A3L8DJR5   A0A195D0A8   B4LED0   A0A1S4ELY3   B4KWK0   E2ASG5   A0A2S2Q326   B3M5G6   A0A0J7KVX5   K7WYY0   A0A0K8WKJ6   J9JXN1   E2BY32   A0A182RVZ8   M9PH99   B4HTZ3   A0A0J9UE83   B3NG30   B4PHP0   P20228   A0A1W4W6H7   A0A182XMB7   A0A182UYD2   A0A182TN96   A0A182KPX0   Q7PNL7   A0A146M6P1   A0A084WRT3   A0A182MFY9   A0A1Q3FUC4   A0A2H8TRP5   K7IUX9   A0A3B0JX11   A0A182PTR5   B4IYX3   A0A067QYW5   A0A182I252   A0A0M8ZR31   Q2LZW7   A0A182JCW1   A0A0A9XU02   A0A182QS79   A0A1B0GGQ7   Q16NG0   A0A336LXE2   A0A182WHZ5   A0A336MQR1   A0A182FCL3   A0A182Y2Z6   B0XFV4   A0A182GBD9   A0A182N846   W5JFV1   U5ELT3   F4X0P1   A0A026W8B3   T1HHW1   B4HBQ2   B4QQ37   U4UIN9   V5K418   T1KSF2   I6SMJ1   A0A0K2V057  

EC Number

4.1.1.15

Pubmed

26354079    22118469    25348373    24495485    25315136    18362917    + More
19820115    28004739    21347285    28648823    17994087    18057021    30249741    20798317    23220582    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    17550304    1689376    12537569    20966253    12364791    14747013    17210077    26823975    24438588    20075255    24845553    15632085    23185243    25401762    17510324    25244985    26483478    20920257    23761445    21719571    24508170    23537049   

EMBL

KP657640    AKL78865.1    KQ460940    KPJ10601.1    NWSH01003345    PCG66503.1    + More
KQ459593    KPI96691.1    AGBW02008571    OWR53023.1    GDHF01017159    GDHF01016022    GDHF01004976    JAI35155.1    JAI36292.1    JAI47338.1    GAKP01022035    GAKP01022034    GAKP01022033    JAC36917.1    GAMC01017141    GAMC01017140    GAMC01017139    JAB89416.1    KQ971351    EFA06442.1    GEDC01001640    JAS35658.1    GEZM01097269    JAV54301.1    ADTU01012083    ADTU01012084    KQ982650    KYQ52902.1    KQ414646    KOC66364.1    NNAY01001694    OXU23203.1    KQ979266    KYN22051.1    JXJN01009715    JXJN01009716    GEBQ01023731    GEBQ01010231    JAT16246.1    JAT29746.1    GEBQ01015013    JAT24964.1    KQ981744    KYN36345.1    CP012525    ALC43026.1    KQ976558    KYM80711.1    CH964095    EDW79365.1    KRF99053.1    CVRI01000075    CRL08726.1    GGMR01012757    MBY25376.1    QOIP01000007    RLU20637.1    KQ977012    KYN06353.1    CH940647    EDW70106.1    KRF84711.1    CH933809    EDW19629.1    KRG06707.1    GL442298    EFN63631.1    GGMS01002911    MBY72114.1    CH902618    EDV39576.1    KPU78089.1    LBMM01002747    KMQ94414.1    KC134205    AFX68715.1    GDHF01000648    JAI51666.1    ABLF02022308    ABLF02022309    GL451412    EFN79405.1    AE014296    AGB94091.1    CH480817    EDW50414.1    CM002912    KMY97484.1    KMY97485.1    KMY97486.1    CH954178    EDV50859.1    KQS43543.1    KQS43544.1    CM000159    EDW93349.1    KRK01117.1    KRK01118.1    X76198    AY089526    AAAB01008960    EAA11955.3    GDHC01003206    JAQ15423.1    ATLV01026194    KE525407    KFB52927.1    AXCM01004956    AXCM01004957    AXCM01004958    GFDL01003845    JAV31200.1    GFXV01004756    MBW16561.1    AAZX01001184    OUUW01000009    SPP84962.1    CH916366    EDV97681.1    KK853095    KDR11483.1    APCN01000120    KQ435896    KOX69217.1    CH379069    EAL31170.1    KRT07941.1    GBHO01020175    JAG23429.1    AXCN02000918    AJWK01000591    AJWK01000592    AJWK01000593    CH477824    EAT35903.1    UFQT01000279    SSX22712.1    UFQT01001601    SSX31123.1    DS232965    EDS27073.1    JXUM01052660    JXUM01052661    KQ561744    KXJ77663.1    ADMH02001620    ETN61760.1    GANO01001281    JAB58590.1    GL888498    EGI60033.1    KK107347    EZA52347.1    ACPB03000438    CH479261    EDW39456.1    CM000363    EDX09157.1    KB632188    ERL89785.1    KC309404    AGT28747.1    CAEY01000425    JQ942360    AFM73660.1    HACA01025990    CDW43351.1   

Proteomes

UP000053240    UP000218220    UP000053268    UP000007151    UP000095300    UP000095301    + More
UP000007266    UP000005203    UP000078200    UP000092445    UP000005205    UP000075809    UP000053825    UP000215335    UP000078492    UP000092460    UP000092443    UP000078541    UP000092553    UP000078540    UP000007798    UP000183832    UP000279307    UP000078542    UP000008792    UP000079169    UP000009192    UP000000311    UP000007801    UP000036403    UP000007819    UP000008237    UP000075900    UP000000803    UP000001292    UP000008711    UP000002282    UP000192221    UP000076407    UP000075903    UP000075902    UP000075882    UP000007062    UP000030765    UP000075883    UP000002358    UP000268350    UP000075885    UP000001070    UP000027135    UP000075840    UP000053105    UP000001819    UP000075880    UP000075886    UP000092461    UP000008820    UP000075920    UP000069272    UP000076408    UP000002320    UP000069940    UP000249989    UP000075884    UP000000673    UP000007755    UP000053097    UP000015103    UP000008744    UP000000304    UP000030742    UP000015104   

PRIDE

M9PH99    P20228   

Pfam

PF00282   Pyridoxal_deC

Interpro

IPR021115   Pyridoxal-P_BS        + More
IPR015421   PyrdxlP-dep_Trfase_major       
IPR002129   PyrdxlP-dep_de-COase       
IPR015424   PyrdxlP-dep_Trfase       

SUPFAM

SSF53383   SSF53383       

Gene 3D

3.40.640.10    

ProteinModelPortal

A0A0G3VI11   A0A0N0PBF8   A0A2A4J514   A0A194PTE4   A0A212FH35   A0A0K8VBT3   + More
A0A034V440   W8B868   A0A1I8PBY7   A0A1I8N673   D6WRJ1   A0A1B6ECJ1   A0A1Y1K1D6   A0A087ZN21   A0A1A9V4B6   A0A1A9ZRZ0   A0A158NCY8   A0A151WYC3   A0A0L7R6C2   A0A232EY01   A0A151JAL0   A0A1B0B7T2   A0A1B6M1D2   A0A1A9YEK3   A0A1B6LN87   A0A195F6W9   A0A0M4EH78   A0A195B879   B4N410   A0A1J1JAW4   A0A2S2P8Z1   A0A3L8DJR5   A0A195D0A8   B4LED0   A0A1S4ELY3   B4KWK0   E2ASG5   A0A2S2Q326   B3M5G6   A0A0J7KVX5   K7WYY0   A0A0K8WKJ6   J9JXN1   E2BY32   A0A182RVZ8   M9PH99   B4HTZ3   A0A0J9UE83   B3NG30   B4PHP0   P20228   A0A1W4W6H7   A0A182XMB7   A0A182UYD2   A0A182TN96   A0A182KPX0   Q7PNL7   A0A146M6P1   A0A084WRT3   A0A182MFY9   A0A1Q3FUC4   A0A2H8TRP5   K7IUX9   A0A3B0JX11   A0A182PTR5   B4IYX3   A0A067QYW5   A0A182I252   A0A0M8ZR31   Q2LZW7   A0A182JCW1   A0A0A9XU02   A0A182QS79   A0A1B0GGQ7   Q16NG0   A0A336LXE2   A0A182WHZ5   A0A336MQR1   A0A182FCL3   A0A182Y2Z6   B0XFV4   A0A182GBD9   A0A182N846   W5JFV1   U5ELT3   F4X0P1   A0A026W8B3   T1HHW1   B4HBQ2   B4QQ37   U4UIN9   V5K418   T1KSF2   I6SMJ1   A0A0K2V057  

PDB

3VP6     E-value=1.44046e-108,     Score=1004

KEGG

101746611    K01580 glutamate decarboxylase [EC:4.1.1.15] | (RefSeq) glutamate decarboxylase

GO

GO:0004351   GO:0019752   GO:0030170   GO:0016831   GO:0016829   GO:0006538   GO:0008345   GO:0045213   GO:0008355   GO:0009449   GO:0007416   GO:0009612   GO:0007528   GO:0005829   GO:0003824   GO:0005667   GO:0005737   GO:0004505   GO:0006559   GO:0004887   GO:0016021  

Length:

375

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.23027

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00298

outside

1  -  375

 

 

Pi

215.377027

Theta

169.856617

Tajima's D

1.405353

CLR

0.022902

CSRT

0.763361831908405

Interpretation

Uncertain