Gene

KWMTBOMO00676

Pre Gene Modal

BGIBMGA003214

Annotation

PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_16_[Bombyx_mori]

Location

Bomo_Chr2(+):224966-234774      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 16      

Alternative Name

Mediator complex subunit 16

Location in the cell

Extracellular   Reliability : 1.15 PlasmaMembrane   Reliability : 1.279

CDS

ATGGAGCTAATATACTCTATGAGACGCAAGCCACTTAAATGTGAACCTCCGCACTTCGAAAATGTAAAAGACTCTGAAGTAGTCCGACCAATATGTACAATATCATGTGCAAATATCATAGCATTCTCATCACCGACAGAGCTTAGTGATGTGGACGGAGCAACATGGGGAGGTCATGTGTATGTATGTGACTTAGATACCCCATGGAACAGTCACAAAGTTACAAGTACAGCTTATCCTGTGTCAGCTCTAGAGTGGGACCTGGAAGGCAAACAGTTGTTAGTAGCCACTACAGTGGGTGATGTGTCTGTCTATGGACAGAAAGACTTCCTCCTCAATGATTGGACATGTCTTTACAGTGCTAACTTCCCTGGAGAACACATAATCCAAGGGGCCTTTTTCCACAATGGACGTCGTGTGGTGGCCGTGGATAAAAAATCAGATGCGGTTATCCCTGAAAAAATACAAATGCTTCGGTTCTCTCCTACTCTCAAGGGATTCGGTGGCGTAGCTTGCGAGGGCGTGCTGGTGGTCACAGCCAGCGGTCTCATCTGTGTGGCAGTGTCCCCGGGCGGAGACTCGAGGACCGCGCTGGTGGCCACCGAAGGCCTTCGCCCCCACAGGGATCACGTCACCGCCGCTGCTATTTGTTATAAAGGTGGCAGCCCCGTGGTGGCGCTGTGCTGCGCGGACGGCTGCGTGCGCTGCGCCGCCGTCACCGTCACCCGCGCGCCCCCCGCCGCCCCCGCGCTCGCCCTGCAGCCGCTGCCAGCCATCCACCTGCTGCACGAGGACCCGCCCGCTGCCGTGGCCTGGAGCTGCCGCGAGGACTCGGACTGCCTGCTGCTGGCGGGCGCCGCGCTGTCGCTGTGGAAGTGCAGCGAGCGGGCGCACCCCGTGCACAAGGTGTTCGCGAAGGGTAACCTGCAGACCAACCCCACCGCGGGGGGCGGGCAGAAGGCGGCCGCGGACTGCTTCAACACCCTGGTGTGGCAGCGCACGGCCGTGCTGCAGCAGGAGGGGGGCCGCGCCGTGTCGGTGTGCGGGGCGCGCTTACCGCAGTCCGTGCCCGCCGTGCTGCTGGCCACGCCGCACGCCGTGCACTACAAGCCCAAGGACAGTCACGTGGCGTTGATCAGCAGGCCGGTGACGAGTCACGGCGCGGCGGACGCGCAGGCCGGGGGCGCCACTCCGCCCAAGAACACTAAATACGGTCCGGGGGTCGCGCCGGGGGGGGCGCGGTGCGCGCTGGTGTCGTGCGCGGCGGTGAGCGCGCAGGGCGGCGCGGCGGTGCTGGTGGACACGCACGGGCAGCTGCACGTGTACCGCCTGCCGCAGGTGTGGCCCGACCTGCTGCTGACCAACCCGGCGCTGTCGGTGCAGCTGGCGGTGAGCGCGCTGGAGTACGCGGCGGTGGCCGGCTGCGACTGTCTCGACGTGCTCATGGCGCTGCGCCCCGGCGCCGCCGAAACCGTCTACGAGAGGTTCACGGAGTCGTTCCAGAGACAGCCGCCGGCAGTGCAGCAGTACTACCAGCAGAGCGCGCTCAAGCTGAGGATAGCTCTGTGCAGGCTGTCGGCCCGGCTGACGGGCAGCGGCGCCTGGCTGACGTGCCTGCAGACGTGCGAGGTCGTGTGGGCGGCCGCCTCCGCCGCGCTCAAGCTGGAGGAGCGGCCCGACGGCGACTGCGAAGAGAACCACATCGAGCAGGATAAGTTGATAGCGTCGCTAGAAGCGAAGGCGGAGGCGGGCGCGGAGCTGGCGGCGCTGCGCGTGTCGGTGCAGCGGGTGGGCGACATCGCCGTCACCGCGCTGCTGTCCCTCTCGCAGCAGCCGCACCACCAGTCGCACGGGTACGAGCTGTGGTCGGACAACGGCGCGGTGTGGCTGCTGCGCAGGGTGCTGGCGCTGTCCCGGGGCACCGGCCGGCCGCACGACGCCGCCGCGCGCTGCCTGGCCCGCCTCGCCGCCGCCGCGCCCGCGCTCAAGCAGGACCTGCTCGGCAGACGAGCATACGGCCCACCTGATGATGAGTGGTTACCGTCGCTCATGGACGTCAGCAATGCCAGGGGCAGAGCCAAGCCGCTGCCCATCTGTGTGCCCCCGGGCACCGCCGCGGAGCAGTCCACTGAAAGCTCGGAGCGTGTCCTGGGAGCTCTGTCACCGTCCGACCCCCTCACGCAGGGGGGCCGGCGGCAGCGCGGGGAGCAGGGGGCTCGAACCGGTGGACGAGCGTGGACCGTTGATGATGATGACCATATTAGTTTTTGTTTTTATGTAATAGAGGAGTGTGCGTCGCTGGTGGCTCAATGTCCGGGGCCGCGCGTGTGGGAGGCGCTCCCCCGGGTCAGTGTCTCGGCGCCTCACCAGAAACCTGGACCCCACTATTTGGAGTACGGAGTAGAGCCTGATTCATTGAAATATGCGCCGGAGCCGCCCCCCTACGTGCAATGTGAAACTACACCCTCTCTAGCCATGGACTCCATACGGTACATGTACCTCGGAGGAGGGTTGAGGCCGGCCCGCTGGCGGGGGTGCGCGCGCTGCGGGGGCAGGGCGCTGGCCGCCGCGCTGCCCGCCAGGCACCCGGCGCACAGGGCCTTCGACGCTCGCTTCGTCTCCAGCTGCAGATGCGGAGGAAAGTGGACGCTGTTCACAAATACTGAAATGAATTCAAACGATAAATAA

Protein

MELIYSMRRKPLKCEPPHFENVKDSEVVRPICTISCANIIAFSSPTELSDVDGATWGGHVYVCDLDTPWNSHKVTSTAYPVSALEWDLEGKQLLVATTVGDVSVYGQKDFLLNDWTCLYSANFPGEHIIQGAFFHNGRRVVAVDKKSDAVIPEKIQMLRFSPTLKGFGGVACEGVLVVTASGLICVAVSPGGDSRTALVATEGLRPHRDHVTAAAICYKGGSPVVALCCADGCVRCAAVTVTRAPPAAPALALQPLPAIHLLHEDPPAAVAWSCREDSDCLLLAGAALSLWKCSERAHPVHKVFAKGNLQTNPTAGGGQKAAADCFNTLVWQRTAVLQQEGGRAVSVCGARLPQSVPAVLLATPHAVHYKPKDSHVALISRPVTSHGAADAQAGGATPPKNTKYGPGVAPGGARCALVSCAAVSAQGGAAVLVDTHGQLHVYRLPQVWPDLLLTNPALSVQLAVSALEYAAVAGCDCLDVLMALRPGAAETVYERFTESFQRQPPAVQQYYQQSALKLRIALCRLSARLTGSGAWLTCLQTCEVVWAAASAALKLEERPDGDCEENHIEQDKLIASLEAKAEAGAELAALRVSVQRVGDIAVTALLSLSQQPHHQSHGYELWSDNGAVWLLRRVLALSRGTGRPHDAAARCLARLAAAAPALKQDLLGRRAYGPPDDEWLPSLMDVSNARGRAKPLPICVPPGTAAEQSTESSERVLGALSPSDPLTQGGRRQRGEQGARTGGRAWTVDDDDHISFCFYVIEECASLVAQCPGPRVWEALPRVSVSAPHQKPGPHYLEYGVEPDSLKYAPEPPPYVQCETTPSLAMDSIRYMYLGGGLRPARWRGCARCGGRALAAALPARHPAHRAFDARFVSSCRCGGKWTLFTNTEMNSNDK

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Subunit

Component of the Mediator complex.

Similarity

Belongs to the Mediator complex subunit 16 family.

Keywords

Activator   Complete proteome   Nucleus   Reference proteome   Repeat   Transcription   Transcription regulation   WD repeat  

Feature

chain  Mediator of RNA polymerase II transcription subunit 16

Uniprot

A0A2W1BSP0   A0A0N1PG06   A0A212F7J6   A0A194PUM9   A0A1B6ICJ1   A0A1B6EV13   + More
A0A1B6LIY8   A0A0A9Z569   A0A067R9H3   A0A2J7QX66   A0A2J7QX62   A0A1B6CD61   A0A1Q3G3Z3   D6WPP8   Q16K67   A0A2K7P6D5   A0A087ZXT0   F4X5R6   A0A1Y1M6W3   A0A158NMC1   A0A195CEF7   A0A154P338   A0A151I340   A0A151K1L1   A0A3L8DUN5   A0A2A3EB66   A0A151IX47   A0A0N0U475   A0A0P4VSI7   T1HRI3   A0A232EKA7   A0A023EYK4   K7IQ99   A0A1B0CL25   A0A151WVN7   A0A026X320   A0A310SWT0   E2ASS0   U4U6W2   N6SWE3   A0A224YYH1   A0A131YQ05   T1IRP9   A0A1E1X3W5   A0A293LUA8   A0A2R5LAE2   J9K1Y2   A0A2S2P3T6   A0A2H8TL81   A0A2S2RAA5   A0A0L0CBN7   A0A0K8W6F2   A0A2R8Q3Q1   A0A1I8QDW5   A0A1A7WRJ4   A0A1A8I9U0   A0A1A8D3Z4   A0A1A8AY75   A0A1A8FQ31   I3JA57   I3JA56   E7F602   A0A1A8MCC4   A0A1A8SHG2   A0A3B5A7B6   A0A3B3RRJ3   A0A3B3RSA6   A0A3P8QJQ6   A0A3P9D091   A0A3B4G540  

Pubmed

28756777    26354079    22118469    25401762    26823975    24845553    + More
18362917    19820115    17510324    21719571    28004739    21347285    30249741    27129103    28648823    25474469    20075255    24508170    20798317    23537049    28797301    26830274    28503490    26108605    23594743    25186727    29240929   

EMBL

KZ149912    PZC78092.1    KQ460940    KPJ10599.1    AGBW02009872    OWR49679.1    + More
KQ459593    KPI96688.1    GECU01023067    JAS84639.1    GECZ01028000    JAS41769.1    GEBQ01016369    JAT23608.1    GBHO01004591    GBHO01004588    GDHC01016563    GDHC01004697    JAG39013.1    JAG39016.1    JAQ02066.1    JAQ13932.1    KK852657    KDR19237.1    NEVH01009393    PNF33171.1    PNF33170.1    GEDC01026078    JAS11220.1    GFDL01000528    JAV34517.1    KQ971354    EFA06850.2    CH477974    GL888742    EGI58156.1    GEZM01038777    JAV81512.1    ADTU01020384    KQ977957    KYM98453.1    KQ434796    KZC05550.1    KQ976507    KYM82785.1    KQ981175    KYN45296.1    QOIP01000004    RLU24170.1    KZ288308    PBC28714.1    KQ980838    KYN12342.1    KQ435834    KOX71552.1    GDKW01001046    JAI55549.1    ACPB03010477    NNAY01003832    OXU18789.1    GBBI01005048    JAC13664.1    AJWK01016852    KQ982701    KYQ51898.1    KK107046    EZA61794.1    KQ759847    OAD62586.1    GL442359    EFN63495.1    KB631740    ERL85695.1    APGK01054198    KB741247    ENN72069.1    GFPF01009613    MAA20759.1    GEDV01007909    JAP80648.1    JH431375    GFAC01005260    JAT93928.1    GFWV01006701    MAA31431.1    GGLE01002375    MBY06501.1    ABLF02036212    GGMR01011510    MBY24129.1    GFXV01002955    MBW14760.1    GGMS01017397    MBY86600.1    JRES01000644    KNC29647.1    GDHF01005854    JAI46460.1    BX000430    HADW01007162    SBP08562.1    HAED01006818    SBQ92943.1    HADZ01022400    HAEA01000475    SBQ28955.1    HADY01020685    HAEJ01002572    SBP59170.1    HAEB01014431    SBQ60958.1    AERX01026346    HAEF01013319    SBR54478.1    HAEI01014650    SBS17119.1   

Proteomes

UP000053240    UP000007151    UP000053268    UP000027135    UP000235965    UP000007266    + More
UP000008820    UP000005203    UP000007755    UP000005205    UP000078542    UP000076502    UP000078540    UP000078541    UP000279307    UP000242457    UP000078492    UP000053105    UP000015103    UP000215335    UP000002358    UP000092461    UP000075809    UP000053097    UP000000311    UP000030742    UP000019118    UP000007819    UP000037069    UP000000437    UP000095300    UP000005207    UP000261400    UP000261540    UP000265100    UP000265160    UP000261460   

Pfam

PF11635   Med16

Interpro

IPR021665   Mediator_Med16        + More
IPR036322   WD40_repeat_dom_sf       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR011041   Quinoprot_gluc/sorb_DH       
IPR017986   WD40_repeat_dom       

SUPFAM

SSF50978   SSF50978        + More
SSF50952   SSF50952       

Gene 3D

2.130.10.10    

ProteinModelPortal

A0A2W1BSP0   A0A0N1PG06   A0A212F7J6   A0A194PUM9   A0A1B6ICJ1   A0A1B6EV13   + More
A0A1B6LIY8   A0A0A9Z569   A0A067R9H3   A0A2J7QX66   A0A2J7QX62   A0A1B6CD61   A0A1Q3G3Z3   D6WPP8   Q16K67   A0A2K7P6D5   A0A087ZXT0   F4X5R6   A0A1Y1M6W3   A0A158NMC1   A0A195CEF7   A0A154P338   A0A151I340   A0A151K1L1   A0A3L8DUN5   A0A2A3EB66   A0A151IX47   A0A0N0U475   A0A0P4VSI7   T1HRI3   A0A232EKA7   A0A023EYK4   K7IQ99   A0A1B0CL25   A0A151WVN7   A0A026X320   A0A310SWT0   E2ASS0   U4U6W2   N6SWE3   A0A224YYH1   A0A131YQ05   T1IRP9   A0A1E1X3W5   A0A293LUA8   A0A2R5LAE2   J9K1Y2   A0A2S2P3T6   A0A2H8TL81   A0A2S2RAA5   A0A0L0CBN7   A0A0K8W6F2   A0A2R8Q3Q1   A0A1I8QDW5   A0A1A7WRJ4   A0A1A8I9U0   A0A1A8D3Z4   A0A1A8AY75   A0A1A8FQ31   I3JA57   I3JA56   E7F602   A0A1A8MCC4   A0A1A8SHG2   A0A3B5A7B6   A0A3B3RRJ3   A0A3B3RSA6   A0A3P8QJQ6   A0A3P9D091   A0A3B4G540  

KEGG

101747027    K15159 mediator of RNA polymerase II transcription subunit 16 | (RefSeq) mediator of RNA polymerase

GO

GO:0016592   GO:0016021   GO:0045893   GO:0005634   GO:0003824   GO:0005515   GO:0008270   GO:0007608   GO:0016020   GO:0005667   GO:0005737   GO:0004505   GO:0006559   GO:0004887  

PANTHER

PTHR13224  

Subcellular location

Nucleus  

Length:

895

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.77236000000001

Exp number, first 60 AAs:

0.00328

Total prob of N-in:

0.12078

outside

1  -  895

 

 

Pi

280.337673

Theta

175.691625

Tajima's D

1.97427

CLR

0.017459

CSRT

0.88245587720614

Interpretation

Uncertain