Gene

KWMTBOMO00651

Pre Gene Modal

BGIBMGA003888

Annotation

arrowhead_PA_[Bombyx_mori]

Location

Bomo_Chr1(-):20064404-20087084      View in EpiBrowser

Full name

LIM/homeobox protein Awh      

Alternative Name

Protein arrowhead

Transcription factor

Homeobox

Location in the cell

Nuclear   Reliability : 2.795

CDS

ATGACGGAGCACCGCACGTGCTGCGCGTGCGGGGAGCCCATCGCCGACCGCTTCTTGCTGGAGGTGGGCGGGGCTGCGTGGCACACCGGCTGTCTCCGATGCTGTGTCTGCGCCGTACAGCTCGACCGGCACCCGTCCTGCTTCCTCAGAGACAGGCAGGTCTACTGCAAGCAGGATTATGCCAAGAGTTTCGGTGCGAAGTGTTCCAAGTGCTGCCGAGGGATATCTTCGTCCGACTGGGTGCGGAAGGCTCGCGAGCAGGTCTACCACCTGGCGTGCTTTGCGTGTGATGCGTGCGGCCGGCAGCTCTCCACGGGAGAACAGTTCGCTCTCCACGAGGACAGAGTGCTCTGCAAGCCACACTACCTCGAAACCTTGGACGGAGGCTCCATTTCATCCGATGACGGGTGTGACTCGGAGGGCTATCACAAGAGTAAAGCGAAGAGGGTCCGGACAACCTTCACCGAGGAACAGCTTCAAGTACTCCAAGCAAACTTCCAGCTAGACTCGAATCCCGATGGACAGGACCTCGAGAGGATCGCGCAGGTGACCGGCCTTAGCAAGAGGGTCACGCAAGTTTGGTTTCAGAATAGTCGCGCAAGACAAAAGAAACATCAGCACACCGGGAAAGGAAAACAGAATCAATTGATGTCCAGGGAAGGGGACGCCGTGGGGTTTGGCAGGCCTATCAACCTACACCTCACTTATTCGTTCCAGAACAAACCGCCATTCGTCCCTATAGACGGTACCTCTTTCACCGACTCTTCAATGGATGAGCTTTCTGAAGATTCTTCGATCCACTGCATGCAGAGTGAAGTCTGA

Protein

MTEHRTCCACGEPIADRFLLEVGGAAWHTGCLRCCVCAVQLDRHPSCFLRDRQVYCKQDYAKSFGAKCSKCCRGISSSDWVRKAREQVYHLACFACDACGRQLSTGEQFALHEDRVLCKPHYLETLDGGSISSDDGCDSEGYHKSKAKRVRTTFTEEQLQVLQANFQLDSNPDGQDLERIAQVTGLSKRVTQVWFQNSRARQKKHQHTGKGKQNQLMSREGDAVGFGRPINLHLTYSFQNKPPFVPIDGTSFTDSSMDELSEDSSIHCMQSEV

Description

Probable transcription factor. Required for the establishment of a subset of imaginal tissues: the abdominal histoblasts and the salivary gland imaginal rings.

Similarity

Belongs to the peptidase S1 family.

Keywords

Alternative splicing   Complete proteome   Developmental protein   DNA-binding   Homeobox   LIM domain   Metal-binding   Nucleus   Phosphoprotein   Reference proteome   Repeat   Transcription   Transcription regulation   Zinc  

Feature

chain  LIM/homeobox protein Awh
splice variant  In isoform A.

Uniprot

G1UCX1   A0A2A4JR89   A0A2W1BIP2   A0A194QXX0   D6WE62   A0A139WM18   + More
A0A1A9Y9Z9   A0A067RGW7   A0A1A9Z8W6   A0A336M0X5   A0A0A1WEE8   A0A1I8PL01   A0A1I8MAV3   A0A1I8PL68   A0A1I8MAV5   A0A0L0CKE9   A0A1B6CXX4   A0A0M4EFP8   B4LDG3   M9PEI5   B4PH67   B3NFY8   A0A0J9UE26   B4HTV0   Q8IRC7   A0A0K8V9V3   A0A0J9RNE5   M9PE75   A0A3B0JWV6   B4GS09   Q2M074   A0A1W4W4V9   A0A1W4VTQ7   B3M802   A0A3B0KIJ7   B4KY96   A0A1J1I579   A0A194PNJ5   B4N593   A0A212EKH1   A0A146LJH2   B4QPZ4   A0A023F5A2   T1I674   A0A0P4VMU8   Q8IRC7-2   A0A0J9RNI5   A0A0J9RPZ2   A0A0K8W5S7   Q16JZ5   B0W839   A0A2S2PYU4   A0A023EN09   J9K3Q1   A0A2S2PKR5   A0A2H8TKF9   A0A084WMM5   A0A182VCD1   A0A182V3L1   A0A182LKK3   Q7PNX2   A0A182Y7Y1   A0A182FFF1   Q7Q5A5   A0A084WMN3   A0A182PZL4   Q16QM8   A0A182IRW6   A0A1A9WCX0   A0A2M4AYT5   A0A023ENP8   A0A2M4BWV5   T1IJP6   B4IZW5   K1RU62   A0A2C9H5R0   A0A182JUB7   A0A182X4C9   A0A182U704   A0A182LKK4   A0NEV0   E9J169   A0A182I4C5   A0A0C9QZL9   E2C3W4   A0A182QTN5   A0A182PRY6   E9FUD2   A0A182RLR9   A0A182LTJ1   A0A0L7QTA5   A0A182NIV4   A0A158N8Y3   F4W9G6   A0A088ANR1   A0A0P5CA31   A0A0P6BF56   A0A182WBV3   A0A182Q807  

Pubmed

28756777    26354079    18362917    19820115    24845553    25830018    + More
25315136    26108605    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    22936249    9331336    12537569    18327897    15632085    22118469    26823975    25474469    27129103    17510324    24945155    24438588    20966253    12364791    14747013    17210077    25244985    22992520    21282665    20798317    21292972    21347285    21719571   

EMBL

AB480539    AB687553    BAK78925.1    BAO05322.1    NWSH01000836    PCG73930.1    + More
KZ150031    PZC74728.1    KQ460953    KPJ10322.1    KQ971318    EFA01311.2    KYB28934.1    KK852645    KDR19538.1    UFQT01000392    SSX23895.1    GBXI01017472    JAC96819.1    JRES01000364    KNC31934.1    GEDC01018966    JAS18332.1    CP012525    ALC43115.1    CH940647    EDW68901.2    AE014296    AGB94074.1    CM000159    EDW93304.2    CH954178    EDV50817.2    CM002912    KMY97430.1    CH480817    EDW50371.1    U82539    AY071197    BT025230    AAB71337.1    AAL48819.1    AAN11572.1    GDHF01016643    JAI35671.1    KMY97431.1    AGB94075.1    OUUW01000009    SPP84912.1    CH479188    EDW40544.1    CH379069    EAL31062.3    CH902618    EDV39910.2    SPP84911.1    CH933809    EDW17675.2    CVRI01000042    CRK95445.1    KQ459599    KPI94314.1    CH964101    EDW79532.1    AGBW02014274    OWR41948.1    GDHC01011577    JAQ07052.1    CM000363    EDX09114.1    GBBI01002429    JAC16283.1    ACPB03000757    GDKW01000072    JAI56523.1    KMY97428.1    KMY97429.1    GDHF01005833    JAI46481.1    CH477984    EAT34603.1    DS231857    EDS38664.1    GGMS01001386    MBY70589.1    GAPW01002825    JAC10773.1    ABLF02038003    ABLF02038011    ABLF02038012    GGMR01017410    MBY30029.1    GFXV01002818    MBW14623.1    ATLV01024486    KE525352    KFB51469.1    AAAB01008960    EAA11386.5    EAA11207.4    ATLV01024497    ATLV01024498    KFB51477.1    AXCN02000477    CH477744    EAT36689.1    GGFK01012645    MBW45966.1    GAPW01003544    JAC10054.1    GGFJ01008415    MBW57556.1    JH430339    CH916366    EDV96737.1    JH816073    EKC38176.1    EAU76621.2    GL767586    EFZ13400.1    APCN01002301    GBYB01001155    JAG70922.1    GL452364    EFN77350.1    GL732525    EFX88940.1    AXCM01014134    KQ414751    KOC61845.1    ADTU01008912    ADTU01008913    GL888030    EGI69141.1    GDIP01173476    JAJ49926.1    GDIP01016067    JAM87648.1   

Proteomes

UP000218220    UP000053240    UP000007266    UP000092443    UP000027135    UP000092445    + More
UP000095300    UP000095301    UP000037069    UP000092553    UP000008792    UP000000803    UP000002282    UP000008711    UP000001292    UP000268350    UP000008744    UP000001819    UP000192221    UP000007801    UP000009192    UP000183832    UP000053268    UP000007798    UP000007151    UP000000304    UP000015103    UP000008820    UP000002320    UP000007819    UP000030765    UP000075903    UP000075882    UP000007062    UP000076408    UP000069272    UP000075886    UP000075880    UP000091820    UP000001070    UP000005408    UP000075881    UP000076407    UP000075902    UP000075840    UP000008237    UP000075885    UP000000305    UP000075900    UP000075883    UP000053825    UP000075884    UP000005205    UP000007755    UP000005203    UP000075920   

PRIDE

G1UCX1    Q8IRC7   

Pfam

PF00046   Homeodomain        + More
PF00412   LIM
PF00089   Trypsin

Interpro

IPR009057   Homeobox-like_sf        + More
IPR001781   Znf_LIM       
IPR001356   Homeobox_dom       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR033116   TRYPSIN_SER       

SUPFAM

SSF46689   SSF46689        + More
SSF50494   SSF50494       

CDD

cd00086  homeodomain
cd00190  Tryp_SPc

ProteinModelPortal

G1UCX1   A0A2A4JR89   A0A2W1BIP2   A0A194QXX0   D6WE62   A0A139WM18   + More
A0A1A9Y9Z9   A0A067RGW7   A0A1A9Z8W6   A0A336M0X5   A0A0A1WEE8   A0A1I8PL01   A0A1I8MAV3   A0A1I8PL68   A0A1I8MAV5   A0A0L0CKE9   A0A1B6CXX4   A0A0M4EFP8   B4LDG3   M9PEI5   B4PH67   B3NFY8   A0A0J9UE26   B4HTV0   Q8IRC7   A0A0K8V9V3   A0A0J9RNE5   M9PE75   A0A3B0JWV6   B4GS09   Q2M074   A0A1W4W4V9   A0A1W4VTQ7   B3M802   A0A3B0KIJ7   B4KY96   A0A1J1I579   A0A194PNJ5   B4N593   A0A212EKH1   A0A146LJH2   B4QPZ4   A0A023F5A2   T1I674   A0A0P4VMU8   Q8IRC7-2   A0A0J9RNI5   A0A0J9RPZ2   A0A0K8W5S7   Q16JZ5   B0W839   A0A2S2PYU4   A0A023EN09   J9K3Q1   A0A2S2PKR5   A0A2H8TKF9   A0A084WMM5   A0A182VCD1   A0A182V3L1   A0A182LKK3   Q7PNX2   A0A182Y7Y1   A0A182FFF1   Q7Q5A5   A0A084WMN3   A0A182PZL4   Q16QM8   A0A182IRW6   A0A1A9WCX0   A0A2M4AYT5   A0A023ENP8   A0A2M4BWV5   T1IJP6   B4IZW5   K1RU62   A0A2C9H5R0   A0A182JUB7   A0A182X4C9   A0A182U704   A0A182LKK4   A0NEV0   E9J169   A0A182I4C5   A0A0C9QZL9   E2C3W4   A0A182QTN5   A0A182PRY6   E9FUD2   A0A182RLR9   A0A182LTJ1   A0A0L7QTA5   A0A182NIV4   A0A158N8Y3   F4W9G6   A0A088ANR1   A0A0P5CA31   A0A0P6BF56   A0A182WBV3   A0A182Q807  

PDB

4JCJ     E-value=8.19109e-26,     Score=289

KEGG

100862786    no KO assigned | (RefSeq) Awh, BmAwh, arrowhead; arrowhead PA

GO

GO:0005634   GO:0046872   GO:0003677   GO:0045944   GO:0000977   GO:0000981   GO:0030182   GO:0010468   GO:0003700   GO:0006355   GO:0048749   GO:0007444   GO:0004252   GO:0008270   GO:0005506   GO:0009072   GO:0008152   GO:0016597   GO:0004505   GO:0006559   GO:0004887   GO:0016021  

Subcellular location

Nucleus  

Length:

273

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00984999999999999

Exp number, first 60 AAs:

0.00873

Total prob of N-in:

0.20884

outside

1  -  273

 

 

Pi

21.329115

Theta

20.777505

Tajima's D

0.110131

CLR

0.046569

CSRT

0.4026798660067

Interpretation

Uncertain