Gene

KWMTBOMO00646  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA003865

Annotation

PREDICTED:_glycine_cleavage_system_H_protein-like_[Papilio_machaon]

Location

Bomo_Chr1(+):20026865-20032745      View in EpiBrowser

Full name

Glycine cleavage system H protein      

Location in the cell

Mitochondrial   Reliability : 1.608

CDS

ATGCTAGCGAGCGGCGCAATACGTGCAGCGACACGGTTCTCAAGATCTGCCTACAGCGGCTACAACGCGGGCTGCTGCAGACACGCGTTGTATTACAGCACTGAAAACAAAATGAGGTACTACACCAAGAAACATGAATGGGTGTCAATTGACGAAAACATCGGAACCGTAGGAGTATCACATTATGCTCAGGATGCGTTAGGAGAAGTTGTATTTATACAGCTGCCTGACGTAGGCCAGGAGATATCAGCCGGTGACGAGAGCGGGGCCCTCGAGAGCGTGAAGGCAGCAGCTGAAGTATACAGTCCTGTGTCGGGAACGGTGACAGAAAAGAACACAGCATTGGAGTCTACACCTTCGTTGGTGAATAAGTCTTGTTACGGGGAAGGTTGGCTGTTCCGCATCAAGCTCTCAAACCGGGATGAGGTGCAGCATTTAATGGACCAGCCGACTTACGACAACTATCTCAAGGAATCTGGCCACTGA

Protein

MLASGAIRAATRFSRSAYSGYNAGCCRHALYYSTENKMRYYTKKHEWVSIDENIGTVGVSHYAQDALGEVVFIQLPDVGQEISAGDESGALESVKAAAEVYSPVSGTVTEKNTALESTPSLVNKSCYGEGWLFRIKLSNRDEVQHLMDQPTYDNYLKESGH

Description

The H protein shuttles the methylamine group of glycine from the P protein to the T protein.

Cofactor

(R)-lipoate

Subunit

The glycine cleavage system is composed of four proteins: P, T, L and H.

Similarity

Belongs to the GcvH family.

Uniprot

H9J2X8   A0A2W1BKD3   A0A2H1VKC6   A0A2A4JPE5   A0A194QYE4   A0A194PLJ9   + More
A0A212EKF4   A0A1B0CS70   A0A1L8E2K4   R4WKC4   A0A1Q3FCT0   A0A1Q3FD15   B0XAY4   A0A182MGP4   Q0IE94   U5EVI3   A0A2M4DPE1   T1DNG6   Q17PI9   A0A182QSW9   A0A2M4DNF6   A0A084WMP1   A0A1B0DIS6   A0A182NIU5   A0A2M4AIJ8   A0A2J7RP67   A0A2M4C1S6   A0A2M3Z8X8   A0A2M4C1R6   A0A182WBU4   A0A2M4C1V5   A0A2M3ZL46   E2BX40   A0A026VUE0   A0A182JFM6   A0A182PRX5   A0A194QFA1   A0A182GLF3   A0A182K926   E2AWJ4   H9JRB5   A0A226F2Z4   A0A0B4J2U2   A0A232F3J0   A0A1I8NYC4   A0A182Y7Y8   A0A151JN10   A0A194QPL1   A0A195BNZ9   A0A158NTS9   A0A0K8R935   W5JCV0   A0A1D2NCT7   A0A131Y0W7   A0A182X4D8   F1L7I3   J3JVI8   S4PAH8   E0W0W4   F4WJ24   A0A0M3KAE7   A0A0L7LTG1   A0A1B6FJW8   A0A195FPK0   A0A023G6D0   A0A0B2UZU2   A0A0K8SYK7   A0A195CV75   A0A0L0CQS4   A0A182LKJ3   Q7PI72   A0A182I4D6   A0A182V7Y1   A0A182TW96   A0A151WLP2   A0A1L8EDH4   L7M6I6   A0A0V0GBY6   T1GHP7   V5HN21   A0A224XZ82   A0A1B6MJC8   A0A224YX98   A0A131Z7I5   A0A154P973   A0A171A1D1   A0A2R5LIS3   A0A023FBR3   W8CBG2   G3MGE3   A0A293MT22   A0A165RB70   A0A131XBX6   T1FMS6   C9W1H0   A0A0P4VMG8   A0A1Y1N7K2   A0A0A1XI15   A0A3P7PZN4   A0A0A1WMZ9  

Pubmed

19121390    28756777    26354079    22118469    23691247    17510324    + More
24438588    20798317    24508170    26483478    20075255    28648823    25244985    21347285    20920257    23761445    27289101    21685128    22516182    23622113    20566863    21719571    26227816    26108605    20966253    12364791    14747013    17210077    25576852    25765539    28797301    26830274    25474469    24495485    22216098    28049606    23254933    20650005    24029695    27129103    28004739    25830018   

EMBL

BABH01031223    KZ150031    PZC74731.1    ODYU01003024    SOQ41273.1    NWSH01000836    + More
PCG73935.1    KQ460953    KPJ10319.1    KQ459599    KPI94311.1    AGBW02014274    OWR41945.1    AJWK01025711    GFDF01001114    JAV12970.1    AK418025    BAN21240.1    GFDL01009661    JAV25384.1    GFDL01009652    JAV25393.1    DS232603    EDS43954.1    AXCM01002601    CH477955    EAT34816.1    GANO01003393    JAB56478.1    GGFL01014790    MBW78968.1    GAMD01002900    JAA98690.1    CH477191    EAT48628.1    AXCN02000477    GGFL01014891    MBW79069.1    ATLV01024498    KE525352    KFB51485.1    AJVK01063079    GGFK01007289    MBW40610.1    NEVH01002140    PNF42630.1    GGFJ01010112    MBW59253.1    GGFM01004201    MBW24952.1    GGFJ01010111    MBW59252.1    GGFJ01010113    MBW59254.1    GGFM01008387    MBW29138.1    GL451202    EFN79759.1    KK111147    EZA46469.1    KQ459252    KPJ02146.1    JXUM01072026    KQ562697    KXJ75313.1    GL443346    EFN62158.1    BABH01016071    LNIX01000001    OXA64159.1    AAZX01005267    NNAY01001139    OXU25013.1    KQ978878    KYN27876.1    KQ461185    KPJ07473.1    KQ976435    KYM87084.1    ADTU01026129    ADTU01026130    GADI01006212    JAA67596.1    ADMH02001752    ETN61173.1    LJIJ01000088    ODN03051.1    GEFM01002897    JAP72899.1    JI173098    ADY46087.1    BT127256    AEE62218.1    GAIX01003259    JAA89301.1    DS235862    EEB19270.1    GL888181    EGI65794.1    UYRR01034021    VDK60166.1    JTDY01000138    KOB78644.1    GECZ01019294    JAS50475.1    KQ981382    KYN42331.1    GBBM01005632    JAC29786.1    JPKZ01002486    UYWY01019948    KHN76576.1    VDM39910.1    GBRD01007507    JAG58314.1    KQ977279    KYN04069.1    JRES01000036    KNC34708.1    AAAB01008960    EAA44254.4    APCN01002303    KQ982959    KYQ48784.1    GFDG01002114    JAV16685.1    GACK01006266    JAA58768.1    GECL01001229    JAP04895.1    CAQQ02131679    GANP01009385    JAB75083.1    GFTR01002853    JAW13573.1    GEBQ01003982    JAT35995.1    GFPF01008075    MAA19221.1    GEDV01001772    JAP86785.1    KQ434846    KZC08383.1    GEMB01001608    JAS01555.1    GGLE01005101    MBY09227.1    GBBI01000339    JAC18373.1    GAMC01004821    JAC01735.1    JO840944    AEO32561.1    GFWV01019224    MAA43952.1    KR028427    AML23853.1    GEFH01003908    JAP64673.1    AMQM01003373    KB096134    ESO08029.1    EZ406118    ACX53917.1    GDKW01002945    JAI53650.1    GEZM01010695    JAV93902.1    GBXI01003671    JAD10621.1    UYYG01001156    VDN56523.1    GBXI01013873    JAD00419.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000092461    + More
UP000002320    UP000075883    UP000008820    UP000075886    UP000030765    UP000092462    UP000075884    UP000235965    UP000075920    UP000008237    UP000053097    UP000075880    UP000075885    UP000069940    UP000249989    UP000075881    UP000000311    UP000198287    UP000002358    UP000215335    UP000095300    UP000076408    UP000078492    UP000078540    UP000005205    UP000000673    UP000094527    UP000076407    UP000009046    UP000007755    UP000036680    UP000037510    UP000078541    UP000031036    UP000050794    UP000267007    UP000078542    UP000037069    UP000075882    UP000007062    UP000075840    UP000075903    UP000075902    UP000075809    UP000015102    UP000076502    UP000015101    UP000274756   

PRIDE

H9J2X8    H9JRB5   

Pfam

PF01597   GCV_H

Interpro

IPR000089   Biotin_lipoyl        + More
IPR002930   GCV_H       
IPR033753   GCV_H/Fam206       
IPR017453   GCV_H_sub       
IPR011053   Single_hybrid_motif       
IPR003016   2-oxoA_DH_lipoyl-BS       

SUPFAM

SSF51230   SSF51230       

CDD

cd06848  GCS_H

ProteinModelPortal

H9J2X8   A0A2W1BKD3   A0A2H1VKC6   A0A2A4JPE5   A0A194QYE4   A0A194PLJ9   + More
A0A212EKF4   A0A1B0CS70   A0A1L8E2K4   R4WKC4   A0A1Q3FCT0   A0A1Q3FD15   B0XAY4   A0A182MGP4   Q0IE94   U5EVI3   A0A2M4DPE1   T1DNG6   Q17PI9   A0A182QSW9   A0A2M4DNF6   A0A084WMP1   A0A1B0DIS6   A0A182NIU5   A0A2M4AIJ8   A0A2J7RP67   A0A2M4C1S6   A0A2M3Z8X8   A0A2M4C1R6   A0A182WBU4   A0A2M4C1V5   A0A2M3ZL46   E2BX40   A0A026VUE0   A0A182JFM6   A0A182PRX5   A0A194QFA1   A0A182GLF3   A0A182K926   E2AWJ4   H9JRB5   A0A226F2Z4   A0A0B4J2U2   A0A232F3J0   A0A1I8NYC4   A0A182Y7Y8   A0A151JN10   A0A194QPL1   A0A195BNZ9   A0A158NTS9   A0A0K8R935   W5JCV0   A0A1D2NCT7   A0A131Y0W7   A0A182X4D8   F1L7I3   J3JVI8   S4PAH8   E0W0W4   F4WJ24   A0A0M3KAE7   A0A0L7LTG1   A0A1B6FJW8   A0A195FPK0   A0A023G6D0   A0A0B2UZU2   A0A0K8SYK7   A0A195CV75   A0A0L0CQS4   A0A182LKJ3   Q7PI72   A0A182I4D6   A0A182V7Y1   A0A182TW96   A0A151WLP2   A0A1L8EDH4   L7M6I6   A0A0V0GBY6   T1GHP7   V5HN21   A0A224XZ82   A0A1B6MJC8   A0A224YX98   A0A131Z7I5   A0A154P973   A0A171A1D1   A0A2R5LIS3   A0A023FBR3   W8CBG2   G3MGE3   A0A293MT22   A0A165RB70   A0A131XBX6   T1FMS6   C9W1H0   A0A0P4VMG8   A0A1Y1N7K2   A0A0A1XI15   A0A3P7PZN4   A0A0A1WMZ9  

PDB

3WDN     E-value=1.31193e-32,     Score=344

KEGG

101743217    K02437 glycine cleavage system H protein | (RefSeq) glycine cleavage system H protein, mitochondrial

PATHWAY

00260    Glycine, serine and threonine metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0019464   GO:0005960   GO:0005739   GO:0007186   GO:0005216   GO:0006355   GO:0043565   GO:0003677   GO:0003707   GO:0004887   GO:0016021  

PANTHER

PTHR11715  

Subcellular location

Mitochondrion  

Length:

161

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01857

Exp number, first 60 AAs:

0.01843

Total prob of N-in:

0.10276

outside

1  -  161

 

 

Pi

14.425509

Theta

18.195837

Tajima's D

-0.740882

CLR

0.042955

CSRT

0.190340482975851

Interpretation

Uncertain