Gene

KWMTBOMO00597

Pre Gene Modal

BGIBMGA012226

Annotation

PREDICTED:_succinate_dehydrogenase_[ubiquinone]_flavoprotein_subunit?_mitochondrial-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr1(-):18073587-18082085      View in EpiBrowser

Full name

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial       + More
Succinate dehydrogenase (quinone)      
Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial      

Alternative Name

Flavoprotein subunit of complex II B
Flavoprotein subunit of complex II

Location in the cell

Cytoplasmic   Reliability : 2.226

CDS

ATGCACCCGGATGATTGGCGCTGGCACTTCTATGATACTGTCAAAGGCTCGGATTGGCTAGGAGATCAGGACTCAATCCACTATCTCACGCGTGAAGCACCAAACGTGGCTATAGAATTGGAAAATATGGGTATGCCATTCTCAAGGACTAAAGATGGCAAGATCTACCAGAGGCCTTTCGGTGGAAGTACCACGCACAACGGTAAAGAAGTGGCTAAAAGGACCTGCTGTGTTGCTGATAGAACCGGTCACGCTCTCCTCCACACTCTCTACGGCTACAGCACCAAGCTGAAGAACATTGACCACTTCGCTGAATTCTTTGTGCTAGATCTTCTGATTCAAGACGGAGTTGTGGTCGGGGCGGTAGCGCTCGACATGGACGACAGCAGTATACACAGGTTTCAAGCAAAGAACACGGTGATCGCAACAGGGGGCTACCCCCGTATGTATTTCTCGTGCACAGCGGCCCACACTTGCACCGGTGATGGATGCGCCATCGCTACGAGAGCTGGTATCATGTTGCAGGACATGGAGTTTGTGCAGTTTCATCCGACAGGCATGTATGGTTCCGGTTGCCTGATGACGGAGGGCTGTCGTGGAGAAGGTGGCTTCCTCGTAAACAGCAAGGGCGAGAGGTTTATGGAGAAGTACGCCCCAAAAGCCAAGGATCTGGCCAGTAGAGATGTAGTCTCTAGATCGATTGCTACCGAGATACGAGAAGGGCGTGGAATAGGACCGAATAAGGACTACGTTCACCTTCAGCTGCACCATTTGAAGCCGGAAGTAATCAAGGAGAGGCTGCCCGGTATTTCGGAGACGGCTTGGACATTCACCGGAGTGGACGTCTACACACAGCCTCTACCGGTCTTGCCGACGGTTCATTATACGATGGGCGGCATCCCAATCAATTACAAGGGAGAGGTTGTGATTCACGAAAACAATAAGGATTGCCCGGTGCCGGGACTGCATGGGGCCGGGGAGGCGGTCAGCAACTGCCACGGCGCCAACCGTCTTGGAGCCAACTCCATTCTTGACATTGTGGTGTTCGGCAAGGCAATCAGCATCAACATTGCAAAGAACAGCAAGCCGGGCGATAAGCAACCAGATTTGAAAGACGTTAGTTGGGCGGCAACAAAAATCTCTCCATATTTTAGTTGA

Protein

MHPDDWRWHFYDTVKGSDWLGDQDSIHYLTREAPNVAIELENMGMPFSRTKDGKIYQRPFGGSTTHNGKEVAKRTCCVADRTGHALLHTLYGYSTKLKNIDHFAEFFVLDLLIQDGVVVGAVALDMDDSSIHRFQAKNTVIATGGYPRMYFSCTAAHTCTGDGCAIATRAGIMLQDMEFVQFHPTGMYGSGCLMTEGCRGEGGFLVNSKGERFMEKYAPKAKDLASRDVVSRSIATEIREGRGIGPNKDYVHLQLHHLKPEVIKERLPGISETAWTFTGVDVYTQPLPVLPTVHYTMGGIPINYKGEVVIHENNKDCPVPGLHGAGEAVSNCHGANRLGANSILDIVVFGKAISINIAKNSKPGDKQPDLKDVSWAATKISPYFS

Description

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic Activity

a quinone + succinate = a quinol + fumarate

Cofactor

FAD

Subunit

Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.

Similarity

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Keywords

Electron transport   FAD   Flavoprotein   Membrane   Mitochondrion   Mitochondrion inner membrane   Oxidoreductase   Transit peptide   Transport   Tricarboxylic acid cycle   Complete proteome   Reference proteome  

Feature

chain  Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial

Uniprot

H9JRR6   A0A194R354   A0A194PLN2   A0A2W1BK54   A0A212EQE2   A0A2A4JDG1   + More
A0A3B4AUQ4   J9K3N0   A0A191XX92   A0A2W1BZK9   A0A182PVF3   A0A182YLX1   A0A212FEF5   A0A3B4G7P0   A0A2S2RB75   A0A3P8QS68   A0A182FM31   A0A147ARB9   A0A182WR96   A0A182MA54   A0A182Q1E1   A0A182ULS7   A0A2M3ZFY9   A0A2M4A5S3   A0A2M4A5Q6   A0A182HX90   A0A2M4BGH8   W5JUV9   A0A146Y486   A0A3B4XN57   A0A3B4UEI0   A0A224X905   A0A182NDK7   A0A182TQ59   A0A182RBD4   A0A182LN92   Q7QDV0   A0A1L8FRX7   M4A3A0   A0A3P9BGU4   A0A336LMK4   Q801S2   H2V735   A0A0P7UCW9   A0A3P9PFF1   F6TAP7   A0A2A2J1Y9   A0A3B3X5B9   A0A0S7F4G1   A0A3B5R1F5   A0A3B5ME57   A0A182J2T0   A0A023FCI3   A0A1W0X758   A0A3N0YGW7   A0A1W4ZQW7   A0A3P9PFD1   I3JJX8   A0A182W3S5   A0A2A2LN39   A0A084VTQ4   A0A1B0CLP4   A0A3P8VWY3   A0A3B3X5H6   A0A2D0S3E3   G3NQT9   A0A3B3CCL3   W5L342   A0A3Q0G352   A0A0K8RS06   A0A0K8RMR7   A0A182KAN5   Q28ED0   A0A3B3UNG4   H3AEC5   A0A131XZB1   A0A146NX27   A0A2I4CI24   A0A3B1JX10   A0A1A7YJJ7   A0A096ZN66   A0A3B3CCJ4   A0A1A8GZF9   A0A3B3VUL3   Q0QF21   G3X1W7   A0A3P8TIU0   A0A3B5ASJ3   H2LNX5   A0A3P9LAZ9   H3AEC4   A0A0F6MX15   B2GQ13   A0A2U9AZ74   A0A3P9IUD8   A0A3P8TLD6   A0A0N5AQQ6   A0A293M1F6   C3YMM1   A0A1I7SBD7  

EC Number

1.3.5.1

Pubmed

19121390    26354079    28756777    22118469    25463417    25244985    + More
20920257    23761445    20966253    12364791    14747013    17210077    27762356    23542700    25186727    21551351    17495919    25474469    24438588    24487278    29451363    25329095    9215903    16751257    21709235    17554307    25875231    18563158    21909270   

EMBL

BABH01017291    KQ460953    KPJ10276.1    KQ459605    KPI92015.1    KZ150069    + More
PZC74085.1    AGBW02013270    OWR43708.1    NWSH01001792    PCG70127.1    ABLF02018996    KU229876    ANJ45171.1    KZ149894    PZC78885.1    AGBW02008935    OWR52136.1    GGMS01018011    MBY87214.1    GCES01005277    JAR81046.1    AXCM01000168    AXCN02001756    GGFM01006662    MBW27413.1    GGFK01002780    MBW36101.1    GGFK01002760    MBW36081.1    APCN01005154    GGFJ01003028    MBW52169.1    ADMH02000002    ETN68137.1    GCES01037928    JAR48395.1    GFTR01007611    JAW08815.1    AAAB01008849    EAA07202.4    CM004477    OCT74354.1    UFQS01000020    UFQT01000020    SSW97497.1    SSX17883.1    BC047261    JARO02014423    KPP58208.1    LIAE01010763    PAV55589.1    GBYX01471314    JAO10336.1    GBBI01000219    JAC18493.1    MTYJ01000013    OQV23244.1    RJVU01042611    ROL45048.1    AERX01010366    LIAE01006560    PAV87568.1    ATLV01016449    KE525091    KFB41348.1    AJWK01017478    AJWK01017479    AJWK01017480    AJWK01017481    AJWK01017482    AJWK01017483    GADI01000354    JAA73454.1    GADI01001448    JAA72360.1    CR848322    BC135730    AFYH01107019    AFYH01107020    AFYH01107021    AFYH01107022    AFYH01107023    AFYH01107024    AFYH01107025    GEFM01003223    JAP72573.1    GCES01150024    JAQ36298.1    HADW01018479    HADX01008097    SBP30329.1    KM098145    AIS22434.1    HAEC01009060    SBQ77276.1    DQ402973    ABD77306.1    AEFK01053046    AEFK01053047    AEFK01053048    KC217615    AGV76821.1    BC164560    AAI64560.1    CP026243    AWO96989.1    GFWV01009182    MAA33911.1    GG666531    EEN58362.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000218220    UP000261520    + More
UP000007819    UP000075885    UP000076408    UP000261460    UP000265100    UP000069272    UP000076407    UP000075883    UP000075886    UP000075903    UP000075840    UP000000673    UP000261360    UP000261420    UP000075884    UP000075902    UP000075900    UP000075882    UP000007062    UP000186698    UP000002852    UP000265160    UP000005226    UP000034805    UP000242638    UP000002280    UP000218231    UP000261480    UP000261380    UP000075880    UP000192224    UP000005207    UP000075920    UP000030765    UP000092461    UP000265120    UP000221080    UP000007635    UP000261560    UP000018467    UP000189705    UP000075881    UP000008143    UP000261500    UP000008672    UP000192220    UP000007648    UP000265080    UP000261400    UP000001038    UP000265180    UP000246464    UP000265200    UP000046393    UP000001554    UP000095284   

PRIDE

H9JRR6    Q801S2    I3JJX8    Q28ED0    B2GQ13   

Pfam

PF02910   Succ_DH_flav_C        + More
PF00890   FAD_binding_2

Interpro

IPR027477   Succ_DH/fumarate_Rdtase_cat_sf        + More
IPR014006   Succ_Dhase_FrdA_Gneg       
IPR015939   Fum_Rdtase/Succ_DH_flav-like_C       
IPR003953   FAD-binding_2       
IPR003952   FRD_SDH_FAD_BS       
IPR037099   Fum_R/Succ_DH_flav-like_C_sf       
IPR036188   FAD/NAD-bd_sf       
IPR011281   Succ_DH_flav_su_fwd       

SUPFAM

SSF51905   SSF51905        + More
SSF56425   SSF56425       
SSF46977   SSF46977       

Gene 3D

3.50.50.60     3.90.700.10    

ProteinModelPortal

H9JRR6   A0A194R354   A0A194PLN2   A0A2W1BK54   A0A212EQE2   A0A2A4JDG1   + More
A0A3B4AUQ4   J9K3N0   A0A191XX92   A0A2W1BZK9   A0A182PVF3   A0A182YLX1   A0A212FEF5   A0A3B4G7P0   A0A2S2RB75   A0A3P8QS68   A0A182FM31   A0A147ARB9   A0A182WR96   A0A182MA54   A0A182Q1E1   A0A182ULS7   A0A2M3ZFY9   A0A2M4A5S3   A0A2M4A5Q6   A0A182HX90   A0A2M4BGH8   W5JUV9   A0A146Y486   A0A3B4XN57   A0A3B4UEI0   A0A224X905   A0A182NDK7   A0A182TQ59   A0A182RBD4   A0A182LN92   Q7QDV0   A0A1L8FRX7   M4A3A0   A0A3P9BGU4   A0A336LMK4   Q801S2   H2V735   A0A0P7UCW9   A0A3P9PFF1   F6TAP7   A0A2A2J1Y9   A0A3B3X5B9   A0A0S7F4G1   A0A3B5R1F5   A0A3B5ME57   A0A182J2T0   A0A023FCI3   A0A1W0X758   A0A3N0YGW7   A0A1W4ZQW7   A0A3P9PFD1   I3JJX8   A0A182W3S5   A0A2A2LN39   A0A084VTQ4   A0A1B0CLP4   A0A3P8VWY3   A0A3B3X5H6   A0A2D0S3E3   G3NQT9   A0A3B3CCL3   W5L342   A0A3Q0G352   A0A0K8RS06   A0A0K8RMR7   A0A182KAN5   Q28ED0   A0A3B3UNG4   H3AEC5   A0A131XZB1   A0A146NX27   A0A2I4CI24   A0A3B1JX10   A0A1A7YJJ7   A0A096ZN66   A0A3B3CCJ4   A0A1A8GZF9   A0A3B3VUL3   Q0QF21   G3X1W7   A0A3P8TIU0   A0A3B5ASJ3   H2LNX5   A0A3P9LAZ9   H3AEC4   A0A0F6MX15   B2GQ13   A0A2U9AZ74   A0A3P9IUD8   A0A3P8TLD6   A0A0N5AQQ6   A0A293M1F6   C3YMM1   A0A1I7SBD7  

PDB

2WQY     E-value=4.74359e-154,     Score=1396

KEGG

101739338    K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] | (RefSeq) succinate d

PATHWAY

00020    Citrate cycle (TCA cycle) - Bombyx mori (domestic silkworm)
00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)

GO

GO:0050660   GO:0006099   GO:0022900   GO:0008177   GO:0005743   GO:0016020   GO:0006121   GO:0000104   GO:0009055   GO:0005749   GO:0045282   GO:0016491   GO:0006355   GO:0043565   GO:0007166   GO:0019752   GO:0030246   GO:0007169   GO:0016021  

Subcellular location

Mitochondrion inner membrane  

Length:

385

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.22598

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01744

outside

1  -  385

 

 

Pi

18.150441

Theta

27.00586

Tajima's D

-1.047446

CLR

0

CSRT

0.129243537823109

Interpretation

Uncertain