Gene

KWMTBOMO00596

Pre Gene Modal

BGIBMGA012226

Annotation

PREDICTED:_succinate_dehydrogenase_[ubiquinone]_flavoprotein_subunit?_mitochondrial-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr1(-):18069746-18072885      View in EpiBrowser

Full name

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial       + More
Succinate dehydrogenase (quinone)      

Location in the cell

Nuclear   Reliability : 3.575

CDS

ATGCAATCGATTACTAATTACAGAATTAAGAATCCTACATATAGAAAGCGAAATATATGCGAGGCGTCATTGGATAATCTGTTTAAAATACGAGATGCCAACGGTACCATTCCGACAGCGGAACTAAGGAACGCCATGAGAAACACGATGCAAAGCAAGTGCGCTGTCTTCAGAGAGGCCAAACTACTGGAAGAAGCTAATCAGGAGATGCTGAAGTGGTATCAGTCATTTAAAGACCTGCGTGTCACGGATCGTCGTCTCAACTGGAACAGCGATCTTGTCGAGAGCTTGGAGCTGCAGAACATGCTGCAACTGGCCATCCAGCTTACGGCCAGCGCTCACAAAAGAACTGAGAGTAGGGGCGCTCATTTCAGAGACGATTACCCTCATAGATGTGACGAAATGGACTATTCCAAGCCAGTCGAAGGCCAGACAAAGAAACCTTTCGACCAGCACTGGAGGAAACACAGTTTAACGATGCTAGACCAGGCCACCGGAAAGGTGACTATAAGCTATCGTCCAGTCATCGATACAACATTGGACGATGAAGTGAAGACAATTCCGCCTGTCCCGAGAGTTTACTGA

Protein

MQSITNYRIKNPTYRKRNICEASLDNLFKIRDANGTIPTAELRNAMRNTMQSKCAVFREAKLLEEANQEMLKWYQSFKDLRVTDRRLNWNSDLVESLELQNMLQLAIQLTASAHKRTESRGAHFRDDYPHRCDEMDYSKPVEGQTKKPFDQHWRKHSLTMLDQATGKVTISYRPVIDTTLDDEVKTIPPVPRVY

Description

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Catalytic Activity

a quinone + succinate = a quinol + fumarate

Cofactor

FAD

Similarity

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Uniprot

H9JRR6   A0A194PLN2   A0A194R354   A0A2W1BK54   A0A212EQE2   A0A2A4JDG1   + More
A0A2H1WCM6   A0A1B6LVW1   A0A183D360   A0A3P6PQC2   A0A182PVF3   A0A1B6FG88   A0A084VTQ4   A0A2H1WLC2   A0A0M3KCD2   A0A023EV92   A0A182GZD1   Q16SE4   B0WFX7   A0A182SHJ4   A0A2M3ZFY9   W5JUV9   A0A182FM31   A0A2M4BGH8   A0A1Q3FY78   A0A1B6E5X9   A0A182J2T0   A0A2M4A5Q6   A0A1Q3FY53   Q8WSR3   A0A232ELA7   A0A1Q3FY46   A0A1Q3FY45   A0A1L8E0S2   A0A0P4X4H5   A0A182WR96   A0A182ULS7   A0A182HX90   A0A182LN92   Q7QDV0   A0A182NDK7   A0A182Q1E1   A0A0P5B7J7   A0A182MA54   A0A182RBD4   A0A182W3S5   A0A1J1J6Z3   A0A2M4A5S3   A0A182KAN5   K7ITI9   A7SCJ3   A0A1B6EY75   A0A1B6EQ31   A0A0A1CQ27   A0A182YLX1   A0A0A1CQ01   A0A194RLM5   A0A1D2MTD8   A0A2C9K3U9   T1H3Q7   M9VDW9   T1E1E5   R7UHX7   B7P620   A0A2W1BZK9   A0A1B6EZ12   A0A1W4WNT7   A0A0P5LEE1   A0A0P5K1D5   A0A1B0CLP4   B3KYA5   G1KJ75   A0A0P5SG45   A0A1W4VHE0   A0A0J9RGM7   A0A1W0X758   F6SI53   A0A1L8E797   A0A1B0G7R7   A0A2J7Q923   B4QE23   T1PAV8   A0A194PVE4   A0A0P5MM86   A0A0P5Q4S6   A0A0M3HW86   K9KEL2   A0A1Z5KV41   A0A0N8B3C6   F1KV78   A0A0P5FW56   V3ZLV6   B3MGG8   A0A0P5G341   A0A1B6IR85   D6WVS3   A0A0P5GC96   A0A0P5LUJ0   A0A0P4WMB9   A0A0B2W091  

EC Number

1.3.5.1

Pubmed

19121390    26354079    28756777    22118469    24438588    24945155    + More
26483478    17510324    20920257    23761445    11803022    21685128    28648823    20966253    12364791    14747013    17210077    20075255    17615350    25244985    27289101    15562597    24330624    23254933    22936249    12481130    15114417    17994087    25315136    28528879    18057021    18362917    19820115   

EMBL

BABH01017291    KQ459605    KPI92015.1    KQ460953    KPJ10276.1    KZ150069    + More
PZC74085.1    AGBW02013270    OWR43708.1    NWSH01001792    PCG70127.1    ODYU01007767    SOQ50820.1    GEBQ01012168    JAT27809.1    UYRT01005209    VDK38189.1    GECZ01020786    JAS48983.1    ATLV01016449    KE525091    KFB41348.1    ODYU01009071    SOQ53224.1    UYRR01034923    VDK62777.1    GAPW01000570    JAC13028.1    JXUM01099388    KQ564488    KXJ72205.1    CH477675    EAT37381.1    DS231921    EDS26512.1    GGFM01006662    MBW27413.1    ADMH02000002    ETN68137.1    GGFJ01003028    MBW52169.1    GFDL01002549    JAV32496.1    GEDC01003948    JAS33350.1    GGFK01002760    MBW36081.1    GFDL01002551    JAV32494.1    JI169558    AB071995    ADY43969.1    BAB84191.1    NNAY01003584    OXU19149.1    GFDL01002555    JAV32490.1    GFDL01002556    JAV32489.1    GFDF01001754    JAV12330.1    GDIP01249472    JAI73929.1    APCN01005154    AAAB01008849    EAA07202.4    AXCN02001756    GDIP01192768    JAJ30634.1    AXCM01000168    CVRI01000073    CRL07754.1    GGFK01002780    MBW36101.1    DS469623    EDO38587.1    GECZ01026919    JAS42850.1    GECZ01032216    GECZ01029733    JAS37553.1    JAS40036.1    KM275751    AIX97507.1    KM275721    AIX97477.1    KQ459989    KPJ18738.1    LJIJ01000544    ODM96389.1    CAQQ02375801    KC161216    AGJ76544.1    GALA01001749    JAA93103.1    AMQN01001266    KB300949    ELU06144.1    ABJB010427648    ABJB010458834    ABJB010601799    DS643501    EEC02042.1    KZ149894    PZC78885.1    GECZ01026678    JAS43091.1    GDIQ01196112    JAK55613.1    GDIQ01196111    JAK55614.1    AJWK01017478    AJWK01017479    AJWK01017480    AJWK01017481    AJWK01017482    AJWK01017483    AK131350    BAG54767.1    GDIQ01096237    JAL55489.1    CM002911    KMY95086.1    MTYJ01000013    OQV23244.1    EAAA01002902    GFDG01004340    JAV14459.1    CCAG010016893    NEVH01016943    PNF25088.1    CM000362    EDX07810.1    KA645063    AFP59692.1    KQ459591    KPI96963.1    GDIQ01177150    JAK74575.1    GDIQ01140423    JAL11303.1    JL641141    AEQ00923.1    GFJQ02007998    JAV98971.1    GDIQ01216851    JAK34874.1    JI166437    ADY41782.1    GDIQ01253143    JAJ98581.1    KB203275    ESO85297.1    CH902619    EDV35711.1    KPU75792.1    GDIQ01251837    JAJ99887.1    GECU01018272    GECU01002633    JAS89434.1    JAT05074.1    KQ971358    EFA09226.1    GDIQ01250389    JAK01336.1    GDIQ01175204    JAK76521.1    GDIP01253414    JAI69987.1    JPKZ01000439    KHN87313.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000218220    UP000050760    + More
UP000075885    UP000030765    UP000036680    UP000069940    UP000249989    UP000008820    UP000002320    UP000075901    UP000000673    UP000069272    UP000075880    UP000215335    UP000076407    UP000075903    UP000075840    UP000075882    UP000007062    UP000075884    UP000075886    UP000075883    UP000075900    UP000075920    UP000183832    UP000075881    UP000002358    UP000001593    UP000076408    UP000094527    UP000076420    UP000015102    UP000014760    UP000001555    UP000192223    UP000092461    UP000001646    UP000192221    UP000008144    UP000092444    UP000235965    UP000000304    UP000095301    UP000036681    UP000030746    UP000007801    UP000007266    UP000031036   

PRIDE

H9JRR6    Q8WSR3    B7P620    B3KYA5   

Pfam

PF02910   Succ_DH_flav_C        + More
PF00890   FAD_binding_2

Interpro

IPR027477   Succ_DH/fumarate_Rdtase_cat_sf        + More
IPR014006   Succ_Dhase_FrdA_Gneg       
IPR015939   Fum_Rdtase/Succ_DH_flav-like_C       
IPR003953   FAD-binding_2       
IPR003952   FRD_SDH_FAD_BS       
IPR037099   Fum_R/Succ_DH_flav-like_C_sf       
IPR036188   FAD/NAD-bd_sf       
IPR011281   Succ_DH_flav_su_fwd       

SUPFAM

SSF51905   SSF51905        + More
SSF56425   SSF56425       
SSF46977   SSF46977       

Gene 3D

3.50.50.60     3.90.700.10    

ProteinModelPortal

H9JRR6   A0A194PLN2   A0A194R354   A0A2W1BK54   A0A212EQE2   A0A2A4JDG1   + More
A0A2H1WCM6   A0A1B6LVW1   A0A183D360   A0A3P6PQC2   A0A182PVF3   A0A1B6FG88   A0A084VTQ4   A0A2H1WLC2   A0A0M3KCD2   A0A023EV92   A0A182GZD1   Q16SE4   B0WFX7   A0A182SHJ4   A0A2M3ZFY9   W5JUV9   A0A182FM31   A0A2M4BGH8   A0A1Q3FY78   A0A1B6E5X9   A0A182J2T0   A0A2M4A5Q6   A0A1Q3FY53   Q8WSR3   A0A232ELA7   A0A1Q3FY46   A0A1Q3FY45   A0A1L8E0S2   A0A0P4X4H5   A0A182WR96   A0A182ULS7   A0A182HX90   A0A182LN92   Q7QDV0   A0A182NDK7   A0A182Q1E1   A0A0P5B7J7   A0A182MA54   A0A182RBD4   A0A182W3S5   A0A1J1J6Z3   A0A2M4A5S3   A0A182KAN5   K7ITI9   A7SCJ3   A0A1B6EY75   A0A1B6EQ31   A0A0A1CQ27   A0A182YLX1   A0A0A1CQ01   A0A194RLM5   A0A1D2MTD8   A0A2C9K3U9   T1H3Q7   M9VDW9   T1E1E5   R7UHX7   B7P620   A0A2W1BZK9   A0A1B6EZ12   A0A1W4WNT7   A0A0P5LEE1   A0A0P5K1D5   A0A1B0CLP4   B3KYA5   G1KJ75   A0A0P5SG45   A0A1W4VHE0   A0A0J9RGM7   A0A1W0X758   F6SI53   A0A1L8E797   A0A1B0G7R7   A0A2J7Q923   B4QE23   T1PAV8   A0A194PVE4   A0A0P5MM86   A0A0P5Q4S6   A0A0M3HW86   K9KEL2   A0A1Z5KV41   A0A0N8B3C6   F1KV78   A0A0P5FW56   V3ZLV6   B3MGG8   A0A0P5G341   A0A1B6IR85   D6WVS3   A0A0P5GC96   A0A0P5LUJ0   A0A0P4WMB9   A0A0B2W091  

PDB

5C3J     E-value=4.00664e-53,     Score=522

KEGG

101739338    K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] | (RefSeq) succinate d

GO

GO:0050660   GO:0006099   GO:0022900   GO:0008177   GO:0005743   GO:0016491   GO:0016020   GO:0006121   GO:0000104   GO:0009055   GO:0005749   GO:0045282   GO:0006355   GO:0043565   GO:0007166   GO:0019752   GO:0030246   GO:0007169   GO:0016021   GO:0055114  

Subcellular location

Mitochondrion inner membrane  

Length:

194

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00038

Exp number, first 60 AAs:

0

Total prob of N-in:

0.39938

outside

1  -  194

 

 

Pi

23.317126

Theta

25.448983

Tajima's D

0.010478

CLR

0.700412

CSRT

0.381630918454077

Interpretation

Uncertain