Gene

KWMTBOMO00556

Pre Gene Modal

BGIBMGA012343

Annotation

PREDICTED:_tyrosine-protein_phosphatase_corkscrew-like_[Amyelois_transitella]

Location

Bomo_Chr1(+):16478369-16518381      View in EpiBrowser

Full name

Tyrosine-protein phosphatase non-receptor type      

Location in the cell

Nuclear   Reliability : 3.021

CDS

ATGTCGAAAGATAATCCAAGGTTGAGCCGGCTCGGAGTGTTGGCGCCGGCTGCCCTGTCGGCCTGCATGGATGCCTCCGTGCTCGCAGTCCCGGCTGCAGGTGCAATCGTCTCCACGGTTCTCAAGGAGTTGAGCAAGGCCTTCATGCTCAAAAAATGGTTCCACGGTGTTATGTCAGCCAAAGAAGCCGAGAGCCTCATCATGGAGAAAGGGAAGAACGGTTCGTTCTTGGTCCGAGAATCTCAGGCGCATCCCGGTGAATACGTGCTGTCTGTCAGAGTCAGAGGTCGAGTTAGCCACGTCCTTATCAGACGACAGCACAACAAATACGACGTAGGTAGCGGTGAGCAGTTCGATGACCTGGTGGGTCTTATTGAACACTTTCGTTCGTATCCGATGATCGAGACATCAGGAGACGTACTGCGTCTCTTGCAGCCTGTTAGTGGCACCAGACTAAGAGCTCACGACATCGACCAGAAAGTACAGGAGATGCAGGGAATAGAAGATCGACAAAAAATGGAATGTAATACCGGTTTCGATGGTGAGTTTCAGTCATTGAAACTGCTTGAAGACAGACACGTGTTCACAACTATCGAGGGAATGAAGCCTGAGAACGTTTCGAAGAACAGATATAGAAATGTATTGCCTTATGACCAAACGCGGGTAGTTCTTCGTCGTCGAGATAACAAACTGGAATCGGACTACATCAACGCATGCTTCGTACGATCGTCGCGTCTCAGTGATTCTACAAGCTCTGTCCAGTCATCGAACGAAAGTCTTGACAGTGTTCAATCGTTGATCCTGAATACTGAAAAGAAGAAGGCAGTACCACTCGTCACGAAATCGCTTTCAGACGACGCTCTGAGAGAAATGAAGAAAAGTCTTAAATTAGATAAAATTAATGGGAATCTAAATAAAGATGCAGTAAAAGACAAAATATATATCGCCGCTCAGGGATGTTTGCCGAGCACTAAGGATGACTTCTGGCGAATGATCTGGCAGGAGGACGTCAGAGTTATAGCGATGATCACGAACGAACATGAAAAGGGGAAGAGAAAATGTGAACGTTATTGGCCATTATCGGGACAGGAAGAGCGATATGACAACCTCCTTGTGAGATCCATTTCTGAGTCGCACTACGAAGATTACCTAATTAGGGAGCTTGACGTATGCGACGAAAATAAATGTTGCAGAGCAGTTTATCAATATCAGTTTACGGCCTGGCCGGACCACAGTACTCCACCGGAGCCGGACAGGATAATCTCATTTATGGAGGATATAAACAGGAGAATGTTTCTAATCACACAAGAGAAAAATGCACCAGATCAGAATGTGATTTGCGTGCATTGTTCCGCGGGAGTCGGGAGAACCGGCACGTTCATAGTCTTGGACATCCTTCTTGACAAAATCAAATCATCTGGTTTTAACTGTGACATCGACGTACACAATACAGTGAAGCTAGTGAGGGCTCAGAGAAGCGGCATGGTACAGAATAAAACCCAATATAGATTCATATATCTCGCCCTTCAGGATTACATTGAAAACAAAAATATTAAATTGAGACGGAAGGGCTACCGGCCGGACATCTGTCGCGACTTCCATCACTAA

Protein

MSKDNPRLSRLGVLAPAALSACMDASVLAVPAAGAIVSTVLKELSKAFMLKKWFHGVMSAKEAESLIMEKGKNGSFLVRESQAHPGEYVLSVRVRGRVSHVLIRRQHNKYDVGSGEQFDDLVGLIEHFRSYPMIETSGDVLRLLQPVSGTRLRAHDIDQKVQEMQGIEDRQKMECNTGFDGEFQSLKLLEDRHVFTTIEGMKPENVSKNRYRNVLPYDQTRVVLRRRDNKLESDYINACFVRSSRLSDSTSSVQSSNESLDSVQSLILNTEKKKAVPLVTKSLSDDALREMKKSLKLDKINGNLNKDAVKDKIYIAAQGCLPSTKDDFWRMIWQEDVRVIAMITNEHEKGKRKCERYWPLSGQEERYDNLLVRSISESHYEDYLIRELDVCDENKCCRAVYQYQFTAWPDHSTPPEPDRIISFMEDINRRMFLITQEKNAPDQNVICVHCSAGVGRTGTFIVLDILLDKIKSSGFNCDIDVHNTVKLVRAQRSGMVQNKTQYRFIYLALQDYIENKNIKLRRKGYRPDICRDFHH

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Similarity

Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.

Uniprot

A0A212EQI6   A0A2A4JVZ2   A0A2W1BB59   H9JS33   A0A2A4JVP3   A0A2H1WQZ9   + More
A0A2A4JVA9   A0A2A4JU47   A0A194QXU9   A0A194RJU9   A0A194Q681   H9IV20   A0A2H1WY52   A0A2A4K380   A0A0L7LLZ9   V5G2H4   A0A195DM14   A0A154PEJ5   D7ELF2   A0A182JH09   V5GJE6   A0A195F3Y8   A0A1J1HPS2   A0A1J1HV72   A0A1Q3FY24   A0A1J1HR93   A0A182ULX7   A0A182LF66   A0A067QLL8   U4U270   A0A182NFH2   Q5TTR3   J3JX41   A0A2R5L5Q5   U4V0R5   A0A084VU59   N6TKK0   A0A1S3HFG4   A0A293LFB0   A0A0A1XPL0   A0A0A1WVB4   A0A1Q3FXY5   A0A1Q3FV42   A0A1Q3FV66   A0A3B5AD19   A0A3B4F223   I3KDR2   A0A3P8R4H9   A0A3P9BLI1   A0A3P8SUJ1   E0VXC8   A0A3B4AX11   T1JTX1   F6WVD2   A0A3B4VQC1   G9KJA0   A0A151NSB1   A0A218V6D8   H0Z8W9   U3K2T1   A0A3Q0G8L8   A0A0T6B2D1   U5ER21   M7B1N1   G3PSG4   F5HK48   A0A182HT30   G3PSG6   A0A182XI48   A0A3B4XDF9   A0A182TBD5   A0A182MX54   A0A094NHH7   A0A0R3T0Z4   A0A151N4C4   A0A3Q0G3B0   A0A0A0ASV2   A0A091LSF2   A0A3B1J9Z1   A0A093L6F5   A0A1L1RU24   A0A093P6M0   A0A226PF42   A0A2I0M3D4   U3J954   A0A0Q3LZE7   A0A226N0A8   R0KFJ5   A0A0R3X2L0   A0A2P4TGI2   A0A1V4KNV7   U6JGQ4   G1MWD5   A0A0R3VSG3   A0A1A8CU23   G1P7X2  

EC Number

3.1.3.48

Pubmed

22118469    28756777    19121390    26354079    26227816    18362917    + More
19820115    20966253    24845553    23537049    12364791    22516182    24438588    25830018    25186727    20566863    25463417    17495919    23236062    22293439    20360741    23624526    14747013    17210077    25329095    15592404    24621616    23371554    23749191    24013640    23485966    20838655    21993624   

EMBL

AGBW02013269    OWR43760.1    NWSH01000575    PCG75552.1    KZ150203    PZC72268.1    + More
BABH01017146    PCG75553.1    ODYU01010354    SOQ55406.1    PCG75554.1    PCG75555.1    KQ460953    KPJ10302.1    KQ460297    KPJ16226.1    KQ459439    KPJ01043.1    BABH01000164    ODYU01011528    SOQ57314.1    NWSH01000210    PCG78378.1    JTDY01000610    KOB76472.1    GALX01004251    JAB64215.1    KQ980762    KYN13534.1    KQ434889    KZC10247.1    DS497846    EFA12064.1    GALX01004252    JAB64214.1    KQ981826    KYN35106.1    CVRI01000015    CRK90056.1    CRK90057.1    GFDL01002632    JAV32413.1    CRK90058.1    KK853191    KDR10028.1    KB632006    ERL87959.1    AAAB01008859    EAL40926.4    BT127809    AEE62771.1    GGLE01000677    MBY04803.1    KI210464    ERL96276.1    ATLV01016641    ATLV01016642    ATLV01016643    ATLV01016644    KE525099    KFB41503.1    APGK01034121    APGK01034122    KB740904    ENN78448.1    GFWV01001828    MAA26558.1    GBXI01001512    JAD12780.1    GBXI01011711    JAD02581.1    GFDL01002679    JAV32366.1    GFDL01003723    JAV31322.1    GFDL01003722    JAV31323.1    AERX01036520    AERX01036521    DS235830    EEB18034.1    CAEY01000486    JP016381    AES04979.1    AKHW03002185    KYO39678.1    MUZQ01000045    OWK61142.1    ABQF01028897    ABQF01028898    ABQF01028899    ABQF01028900    AGTO01020434    LJIG01016140    KRT81496.1    GANO01003972    JAB55899.1    KB585326    EMP25998.1    EGK96889.1    APCN01000403    AXCM01003184    KL361808    KFZ65951.1    UZAE01000147    VDN96378.1    AKHW03004073    KYO31537.1    KL872854    KGL96947.1    KK509203    KFP62453.1    KK598797    KFW04891.1    AADN05000197    KL225141    KFW67902.1    AWGT02000089    OXB78182.1    AKCR02000044    PKK24176.1    ADON01000006    ADON01000007    LMAW01002900    KQK75864.1    MCFN01000301    OXB61007.1    KB742382    EOB09216.1    UYWX01020379    VDM31911.1    PPHD01000442    POI35466.1    LSYS01002427    OPJ86103.1    LK028589    APAU02000020    CDS23237.1    EUB61468.1    UYRS01000008    VDK20229.1    HADZ01018260    SBP82201.1    AAPE02037827    AAPE02037828   

Proteomes

UP000007151    UP000218220    UP000005204    UP000053240    UP000053268    UP000037510    + More
UP000078492    UP000076502    UP000007266    UP000075880    UP000078541    UP000183832    UP000075903    UP000075882    UP000027135    UP000030742    UP000075884    UP000007062    UP000030765    UP000019118    UP000085678    UP000261400    UP000261460    UP000005207    UP000265100    UP000265160    UP000265080    UP000009046    UP000261520    UP000015104    UP000002280    UP000261420    UP000050525    UP000197619    UP000007754    UP000016665    UP000189705    UP000031443    UP000007635    UP000075840    UP000076407    UP000261360    UP000075901    UP000075883    UP000046398    UP000278807    UP000053858    UP000018467    UP000000539    UP000054081    UP000198419    UP000053872    UP000016666    UP000051836    UP000198323    UP000046396    UP000274429    UP000190648    UP000019149    UP000001645    UP000046400    UP000282613    UP000001074   

PRIDE

H9JS33    H9IV20   

Pfam

PF00102   Y_phosphatase        + More
PF00017   SH2
PF06916   DUF1279

Interpro

IPR000242   PTPase_domain        + More
IPR016130   Tyr_Pase_AS       
IPR036860   SH2_dom_sf       
IPR029021   Prot-tyrosine_phosphatase-like       
IPR000980   SH2       
IPR000387   TYR_PHOSPHATASE_dom       
IPR003595   Tyr_Pase_cat       
IPR012152   Tyr_Pase_non-rcpt_typ-6/11       
IPR009688   DUF1279       

SUPFAM

SSF52799   SSF52799        + More
SSF55550   SSF55550       

Gene 3D

3.30.505.10     3.90.190.10    

ProteinModelPortal

A0A212EQI6   A0A2A4JVZ2   A0A2W1BB59   H9JS33   A0A2A4JVP3   A0A2H1WQZ9   + More
A0A2A4JVA9   A0A2A4JU47   A0A194QXU9   A0A194RJU9   A0A194Q681   H9IV20   A0A2H1WY52   A0A2A4K380   A0A0L7LLZ9   V5G2H4   A0A195DM14   A0A154PEJ5   D7ELF2   A0A182JH09   V5GJE6   A0A195F3Y8   A0A1J1HPS2   A0A1J1HV72   A0A1Q3FY24   A0A1J1HR93   A0A182ULX7   A0A182LF66   A0A067QLL8   U4U270   A0A182NFH2   Q5TTR3   J3JX41   A0A2R5L5Q5   U4V0R5   A0A084VU59   N6TKK0   A0A1S3HFG4   A0A293LFB0   A0A0A1XPL0   A0A0A1WVB4   A0A1Q3FXY5   A0A1Q3FV42   A0A1Q3FV66   A0A3B5AD19   A0A3B4F223   I3KDR2   A0A3P8R4H9   A0A3P9BLI1   A0A3P8SUJ1   E0VXC8   A0A3B4AX11   T1JTX1   F6WVD2   A0A3B4VQC1   G9KJA0   A0A151NSB1   A0A218V6D8   H0Z8W9   U3K2T1   A0A3Q0G8L8   A0A0T6B2D1   U5ER21   M7B1N1   G3PSG4   F5HK48   A0A182HT30   G3PSG6   A0A182XI48   A0A3B4XDF9   A0A182TBD5   A0A182MX54   A0A094NHH7   A0A0R3T0Z4   A0A151N4C4   A0A3Q0G3B0   A0A0A0ASV2   A0A091LSF2   A0A3B1J9Z1   A0A093L6F5   A0A1L1RU24   A0A093P6M0   A0A226PF42   A0A2I0M3D4   U3J954   A0A0Q3LZE7   A0A226N0A8   R0KFJ5   A0A0R3X2L0   A0A2P4TGI2   A0A1V4KNV7   U6JGQ4   G1MWD5   A0A0R3VSG3   A0A1A8CU23   G1P7X2  

PDB

2B3O     E-value=1.31783e-75,     Score=721

KEGG

101736863    K07293 tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48] | (RefSeq) tyrosine-protein p

PATHWAY

04013    MAPK signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0004725   GO:0005737   GO:0060027   GO:0003146   GO:0060548   GO:0060028   GO:0048703   GO:0016740   GO:0036302   GO:0032991   GO:0046326   GO:0001784   GO:0046676   GO:0042445   GO:0071364   GO:0060125   GO:0070374   GO:0048806   GO:0032755   GO:0004726   GO:0060020   GO:0007229   GO:0021697   GO:0048873   GO:0005634   GO:0007173   GO:0005158   GO:0061582   GO:0048013   GO:0035855   GO:0000187   GO:0051463   GO:0060325   GO:0043254   GO:0046887   GO:0033277   GO:0051428   GO:0035264   GO:0032728   GO:0009755   GO:0048609   GO:0045931   GO:0030971   GO:0050839   GO:0005070   GO:0046628   GO:0048008   GO:0033629   GO:0032760   GO:0035265   GO:0000077   GO:0032528   GO:0048011   GO:0030220   GO:0042593   GO:0006641   GO:0048839   GO:0007409   GO:0046825   GO:0006470   GO:0016311   GO:0016791   GO:0035023   GO:0005515   GO:0019752   GO:0030246   GO:0007169   GO:0016021  

Subcellular location

Cytoplasm  

Length:

535

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

7.41588999999999

Exp number, first 60 AAs:

7.40737

Total prob of N-in:

0.31107

outside

1  -  535

 

 

Pi

27.349102

Theta

26.88763

Tajima's D

0.178211

CLR

0.036805

CSRT

0.425778711064447

Interpretation

Uncertain