Silkworm Genome Informatics Database

Gene

KWMTBOMO00550 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012338

Annotation

PREDICTED:_E3_ubiquitin-protein_ligase_MYCBP2-like_[Bombyx_mori]

Location

Bomo_Chr1(+):16312000-16341443 View in EpiBrowser

Full name

E3 ubiquitin-protein ligase MYCBP2

Alternative Name

Myc-binding protein 2
Protein Esrom

Location in the cell

Nuclear Reliability : 1.633 PlasmaMembrane Reliability : 1.427

CDS

ATGGCACTCAGGGTACCAACACCAGAGCTAAGCTGCATAGATCCCGAGAACTACAGACAGTATTTTAGAGCCTTATGCTGGAGTGGCACAAGGCGATCCATATTGGCCCGTTGGAGAAATCTCCAAAGTAATTCTTCAGAGGCATCTGATGACAGCGACAATGAAGAAGGTGTTTCCCCAGTTCCTATCAACAAATTGCCTAAGATCACAGGAGTAGGTCTTCGTACAGTTTTCTCTCTTATTTCACAAGCTAAGATAACCAATCCGCATTTTTGCGAGCAAGCGTTAAAAGCACTCTTAGATGTACTGCAAGGGCATTCTCCTGAAGAGCTTTCGCAAGAACCAACCGATATGATCTTTAATATACATTCTATGCTAGTTGAAGTGTCTAGTGGTGTGAGCCCTAGTGGTCGTTCTGAACATCCTTCAAAACTCACAGCTTTAAGCAGCTCTTGTTTAATTGCATTGTCAGTCGCACGTGGCGAAGCTGAATTAATATTAAATGCAGCGGCCTCCTTGGCAATGTGTGCTCCATTGTACTTAGACCAATACTTGAAGACTCCTGCAAATCTGACCACGCTACAACGAAGCGTTCAGTCCGTTATTCTGGGTTCTCCATCCCGTAACCAGTGGTTGCAGTACGGTGTACCATCACTGTCGCTCATCAACAGTTTTCCTGTAGATCTTCCAGTTTCGTTAACGTCTGGTTCGGGTGACCTAGTTGTACGGTCTCTTGTATCGGACGGTTGTTATCTCTATGTTTTCACTTCCAAAGGATTGTTGAAGATTGGCTCTGGTTATGGCAGTTCTATAAAGCAACATGTTTATTCTTATAAACCAGATTTTTTCGCGGGTGAGCGACATGGATGGCTTGGGTATTGTAGAACTAAGTTGTTTGTAAGAATTGGTAGAAAAAAGACTGATATCTACGAAATAGATAGAGATACACTAGAAGTACGACAAACAATCAAATTAGATCCAGGGCTACCAGCACCGATTGAATCTAAATCCGCCGTGTTTAGTGATGGCAATCAAATTGGGCTAATCTTACTCACAAAATTTGACACGTTGACGATACGAATGTATAGTGTGGACACTGCAAGTCGTCAGGAAGGAACAAACATCTTGACTTCACAGAAAGAATTCAATGTGCACTTATTAAGGCGTAGAACGTTAGTAATGGGTCGGGCGCCATTCGAAGACATCCTGCCACGTCGGCCCCTTGATATGGACGTACCGGTTGCAACACAACTTGATGATAATGACGACGACCCCCTCTTGAGTATTTGTGGGGGACAAGAATTTGGACTGCTAGCAACTGTATCAGGAAAGGTATATTACTGCGGCAAAGGCAGTAGTCTCGGTTACAAAGCGGCATCTGCTAACACAAAAAAATGGACTTTAATGAAAGAAACAACAGTCACGAAGAACGAAGCGCCGAATGCAAAAAAAGCAAAAATTGCTCAGGTGGCCGTCGGTCATGAGGGCGTACACGCTATATTAGTACTAGACAACGGCACGGCTTTGTTTACCGGTGTGGCAAGACGAGGAGAAGATGGTGATGCGATCAGACATCGACGGACACCAAAACCTACAAGGCCTAAAAAGATATTCAAGGCTGAAGGACATCACATAGTTTATGCGGCTTGTAACTATGGCTCCACCGCTTTGGTAACGCGTCAAGGTCTCTTACTAATGTTCGGAAAAGACACCCTGCATTGCGATTCGTCGGGACTAGTTCTCGGTCTCAGACACGAACGAGTCATACAGGTGGCGCTAGGGAAAGCTCATGCAGTTGTTTTAACGAGCTTCGGACTGGTCTATACCCTTGGTATAAACAATAAGGGACAGTGCGGTCGCGAATTTGGATATACAAAAGAAAAACCGTCTCATTCTCGTCATCATGACGAGAACAAAGACGAAGCCCGCATATGCCAGACGCCGCATAGCTGGACGACGGACTATTGTCGCGTGTGCGTGCTCTGCTGCGAGTGCACGGGATTCTCTAATGCGTGCCATTGCTCTCATTTACCAAACAGAGTGCCCGGAGAAAAGTGTGGGTGCGGTGAAGGCGATAGCGGCTGCAGCGTTTGTGGAATTTGCCGTCGATGTGCGGACGCGTTTGCCGCGGCCGGACGCGCCGAATGTACCGAGCGTGTCTCGGACGCCGACGACGACGCGGACGCCGAGACATCGACCGCAGCAGAAGCTAAGAATGACCCGGAGCCATCGAGGTATACGCAATACGAGGGACATTCAAGCGGTCTAGACGATAGAGACACCAGCTTCAAAGTGAGTTGTCTTCCGCCTGCTCGCGTGGCTGTGCCCGGAGGACACCGCGTCGCGGCCGTTGCGTGTGGGCTTCATCATACTGTGCTACTCACCGAACATGGTGAAGTCTTGACATTCGGCTCAAACCAGTTTGGTCAGTTGGGCGCAGGCGATATATCAACACATCATCGAATAATCCGAGTAAAGGTACCTAAAGCTTCAGCCATCGCGGCTGGCAGTAATCACACTGCTGTCCTGACTAGAGATGGAGAACTTTTCACTTTTGGCAGTTATCAGAAAGGGTCACTCGGTCGTCCTTGCGATGACGACGCGCCTCGCTCGGAGAGAGGTCTGATATGGTACGCTACCCCAGGGAGAGTACCCCGACTGGGTCCGCGGTATTCATGCAAGGCCGTTTGGATTTCGGCTTCAGGGGACCAAACATTCGTGCAAATCTCTCAAGCTCTCATCAAAACCGATACGCTTTTCAGCTCGACCATTACTTCCAACAATAACTGTATTCTGATTCTTCCGAATCGCCCGGAGCACACATTTAAATGTCTGACCATCAATAAGAACGACGGAACTTGTAATGCTTGGACAGGTTCAGAACAAGTCGACTTTGTAAACACACTCGCGTGCCTCGATCCGCTTTACGATGTCCTGTGGTGCTACCATCCTCAGGTGCAAGTGATAAGATGTTACAACATACTAGCATTCGATGCGCACAAGATACAGAGGTGCTGCAACAATGACCCTGACGGTTACGATGACGACAATGATTTCGATTATCCGAGCTGCGGAAACATGAGGCGCTTGGAAGATTTCAAGAACTTGGAGAGTTTCGAAGTGACATGCAGTAATGAAGAGAAGCCGACCGATATCGTGGCTCTAGTGAACATGTCGGTTCTGAGCCAAGAGCTGGCTATACCGTGTGCGCCAAAGTGTTCAATCACACGAATGCACGCGGTCCTGCATCTGCTCGCGTGTCTCGACTCCCTGAACTATGCACACGATAACAAGCTGAGTCAAGTGGAGTGTAAACGAGACAACGCGTCTGCTCCAGAGGCGTCCATGAAAGAGGACTTCCTCACCGTGAACCGTTTCGAGAGCCACGGCGGAGGGTGGGGATACTCTGGACATTCCGTTGAAGCTATACGGTTTATGTGCGACACCGATATATTGCTAGGCGGTTATGGGCTGTTTGGGGGTCGTGGGGATTACACTGCGAAGATAAAGTTATATGACATTGGACTTGACGGCGGAGATCAAGAGGCTGATGGTGAATTGTTAGCCGAGAGCGACGAAATTGTATTCGAGTGCGCGCCGAGGGATCGTTTCCCGGTACTGTTCGAAACACCAGTACCAATAGTTGCAAACCGATGGTATTTGGCGTGGGCTTGCATGAACGGTCCATCATCGGACTGTGGTTCTTCGGGACAAGCGATGGTAATAAATGATGAAGTCGGTTTCCATTTCAAATCCTCAAAGAAATCGAACAACGGTACCGACGTTAATGCTGGGCAGATACCGTGCCTCCTGTACAATATTGCAACGCCCGATCATAATCTTCCAATGAGGATTACCGACCCGGGAGAACCAATAATTCCTCTCAGTAAAAATATATCAAGGAAAGTTACAGTGCCGTGCTTCAGATCTTTAATATCACTATTAACTTGGGGATGGGCATCTTTAAAAGAATTCATTTTGGACACGAACGGACAGATTCCTATTACCTACCAAAAACTGCTGTTGATGAAGCAGCAAAAGCGATTAGTGTACGTGGTGAGGTCTTGTCTGAGACTCGTGAAGTTCTACATCAACGAAATATACCCTCAAAACAACAGAAAACGCAATTCGCACGAGTATATGTCATACTTTGAATCCATAGGAGAAGTGAGGAATTTAATACAAATGATAATGGCCGATTGTACCCCAACTTGCTCTCGGATCCCAAGACGAGTGGGCAGGATTAGGTCTAGTCGAGTTTGCTATGTTCAGTTTGCGTTGGAGCTGATGCATTCAGTTTTCAATGAGGCACACGACACGGTCACTGCCTGTTTTCACGCATTCTTTCCGACGCCCACTTTAAAATGGAACCACATGTGCAGCCTGCTATTTTATGTAAAGGAGGGCACAGTGCCTCCTGCCCAAATTCGTGAGCTGACGGCTACTTGTGCCGCGATGTGTGTATCAAGGAGTCTGCGAGATGTTCTGCAATACATAGTTCCCGTCACTCAAAATTATCTCATAACGCATGAGAATAAGCGCCCCGATAGTAAAGTGGTTATCAAAGAGATGCCATTGAAATCGGCGACCGTACCTAGATCATCGTACGCCCAGAAGCCACCTCCTATTCCGCCCAGAACGGGAAATATGGAATCACCGAAGTTTCAAGAGACGACTGAAACGAAGCAGAACTTCAGCGACTGGCATCTGTTGGATGTGATTACCAAACTACTCGATATTGTACTTCTTCCGATCAAGCGTCAGATGATGACGCGTCCTTGCAACCAGCCTCACGATCACGGCGAGATCAAGCAACACGAACGACTCGCCGAGTTTTGCTGCAAACTTACCGTCAGAATAGTCGCCGAACTTACCCACAGCACTGCCAATATTAGGGACGACGTGGACTCTAGTTCGGTGAAACACTTAGTGACGCCTTCGCGTTTTATGCGCGTCAATCAGTCGCGCGCCTGGAACACCGGCAACGGAAGTCCGGATGCTATATGCTTTACCGTCGATCGGTCCGGCGTTATGTTGGTCGGGGTTTGCGTTTACGGCGGCCCCGGTAACTACGAATACTCGATCGAGCTGCTGAACGACGTCAGGTCACGGTCGTCCCCGGAAGAAATGAATCCTGCTCATTGTTGGGTTAGCGTCGAAGTTGCTCACGGCGCTTTCAGTGGAGCCGAGTGTCAGCACGATATGGTGCAGTTGAAATTTGACCGCCCAATACTTTTGAAAGAAGAGATTCGTTACGCTATACGACTATGTAATCATGGTGGTCGAACGGCCAATGGTGACTGCGGTCTTCCTTCGGTGAAGGGCCCTGACGGAACAACCTTCCGTTTTGCTTCTTGCTCTCTAAGCTTCAATGGAACTACTCTGGCTCGAGGACAGATACCTTGCCTCGTTTACTATTCGCGTTCGTCTACAACTTCGCTCTGCAGCTCGGAGAGTACTGACTCTCTGGTCACCGCCCTTCGTACTATAACATTACGAGTGGCGTCCTTAGTAATGGAGAGGGGCTCGGAGCTGTTTTGTACTTTGCGCAATGAGCTTACGGCCGAGGATCTCAAGAGGAATGCCTCTGTGCTGCAACAATCGCCAGCTATCAATACACTCATACCCTATACTCTGGCCAGCCTGGATGGACTTGACGATCCAAAGAGCGTAATCAAAATATTGGAAATGATCCGGAAACTTTTACCACACGTGGGTGCTATGAATCTACTCGTGCCTTCCGTGGAGGAGACCAATATAAACACGACCGCGGCCCAATACTACAGTTGGGTCGAAAGTGAGCACCCATACAAGCAGGCGACTGTCACCAACATGAGAGTGCTGTTTCCGACTACGGTGTCGTGGATTGTATTGGAGATGGATCCGAGGAGTATAACAGCTCAGCCCGAAGACACGCTCACTGTATTCGCTGTGGCTGGAGCACCGAAACACAAGTGTCATTGTACTGAAGAGCCTCGTACCGATATACCGTTTAAGAAGCGTCTAGTACATTTGGGGCCGGAAGGCGATTTTGACGATTACGTAGAAGCAGTTGACACGGACGCCCCGTGCATGCAATATAACTGCACTTACGTCAGCGTCACACCTAAGCTCTCCAACGTAGCAACTGAATGGCCGCAAAGGTCGTTGCTGGTGCCGGGAAACGAAGTGATATTTTCACTGGAAACAGCCTCAGATTATCTCACCGAATACAATAAAGCTAACAACGAAGAGAACCGTTTCGGTTTTCGTTGTCTGGCCGTTGGCTACGAGGATTCCAACTTGACATCGCAGAAGCAAGGTCTGGTCGCCCTAGAGATGGACCTCATGTTCACCGGTGCGGCGTGCGCTTCGAAACTGCTCGCACCCGATCTTGAGATACCTCCGATGAGTTTCGCAACACTACTAGAAGTACAGCTTCAAGCAATGATAGGAGGCAACCCTACCGGAGGCGAGGACGAAACTCCCCAAGATGCTTGCGAAACGCTTTTCCTATCCCGGGGACTCGATCTGACTTCACTTCCAACAGTTCATCAAATTTTTGATGACCAATCTCTTCAGCAGTGA

Protein

MALRVPTPELSCIDPENYRQYFRALCWSGTRRSILARWRNLQSNSSEASDDSDNEEGVSPVPINKLPKITGVGLRTVFSLISQAKITNPHFCEQALKALLDVLQGHSPEELSQEPTDMIFNIHSMLVEVSSGVSPSGRSEHPSKLTALSSSCLIALSVARGEAELILNAAASLAMCAPLYLDQYLKTPANLTTLQRSVQSVILGSPSRNQWLQYGVPSLSLINSFPVDLPVSLTSGSGDLVVRSLVSDGCYLYVFTSKGLLKIGSGYGSSIKQHVYSYKPDFFAGERHGWLGYCRTKLFVRIGRKKTDIYEIDRDTLEVRQTIKLDPGLPAPIESKSAVFSDGNQIGLILLTKFDTLTIRMYSVDTASRQEGTNILTSQKEFNVHLLRRRTLVMGRAPFEDILPRRPLDMDVPVATQLDDNDDDPLLSICGGQEFGLLATVSGKVYYCGKGSSLGYKAASANTKKWTLMKETTVTKNEAPNAKKAKIAQVAVGHEGVHAILVLDNGTALFTGVARRGEDGDAIRHRRTPKPTRPKKIFKAEGHHIVYAACNYGSTALVTRQGLLLMFGKDTLHCDSSGLVLGLRHERVIQVALGKAHAVVLTSFGLVYTLGINNKGQCGREFGYTKEKPSHSRHHDENKDEARICQTPHSWTTDYCRVCVLCCECTGFSNACHCSHLPNRVPGEKCGCGEGDSGCSVCGICRRCADAFAAAGRAECTERVSDADDDADAETSTAAEAKNDPEPSRYTQYEGHSSGLDDRDTSFKVSCLPPARVAVPGGHRVAAVACGLHHTVLLTEHGEVLTFGSNQFGQLGAGDISTHHRIIRVKVPKASAIAAGSNHTAVLTRDGELFTFGSYQKGSLGRPCDDDAPRSERGLIWYATPGRVPRLGPRYSCKAVWISASGDQTFVQISQALIKTDTLFSSTITSNNNCILILPNRPEHTFKCLTINKNDGTCNAWTGSEQVDFVNTLACLDPLYDVLWCYHPQVQVIRCYNILAFDAHKIQRCCNNDPDGYDDDNDFDYPSCGNMRRLEDFKNLESFEVTCSNEEKPTDIVALVNMSVLSQELAIPCAPKCSITRMHAVLHLLACLDSLNYAHDNKLSQVECKRDNASAPEASMKEDFLTVNRFESHGGGWGYSGHSVEAIRFMCDTDILLGGYGLFGGRGDYTAKIKLYDIGLDGGDQEADGELLAESDEIVFECAPRDRFPVLFETPVPIVANRWYLAWACMNGPSSDCGSSGQAMVINDEVGFHFKSSKKSNNGTDVNAGQIPCLLYNIATPDHNLPMRITDPGEPIIPLSKNISRKVTVPCFRSLISLLTWGWASLKEFILDTNGQIPITYQKLLLMKQQKRLVYVVRSCLRLVKFYINEIYPQNNRKRNSHEYMSYFESIGEVRNLIQMIMADCTPTCSRIPRRVGRIRSSRVCYVQFALELMHSVFNEAHDTVTACFHAFFPTPTLKWNHMCSLLFYVKEGTVPPAQIRELTATCAAMCVSRSLRDVLQYIVPVTQNYLITHENKRPDSKVVIKEMPLKSATVPRSSYAQKPPPIPPRTGNMESPKFQETTETKQNFSDWHLLDVITKLLDIVLLPIKRQMMTRPCNQPHDHGEIKQHERLAEFCCKLTVRIVAELTHSTANIRDDVDSSSVKHLVTPSRFMRVNQSRAWNTGNGSPDAICFTVDRSGVMLVGVCVYGGPGNYEYSIELLNDVRSRSSPEEMNPAHCWVSVEVAHGAFSGAECQHDMVQLKFDRPILLKEEIRYAIRLCNHGGRTANGDCGLPSVKGPDGTTFRFASCSLSFNGTTLARGQIPCLVYYSRSSTTSLCSSESTDSLVTALRTITLRVASLVMERGSELFCTLRNELTAEDLKRNASVLQQSPAINTLIPYTLASLDGLDDPKSVIKILEMIRKLLPHVGAMNLLVPSVEETNINTTAAQYYSWVESEHPYKQATVTNMRVLFPTTVSWIVLEMDPRSITAQPEDTLTVFAVAGAPKHKCHCTEEPRTDIPFKKRLVHLGPEGDFDDYVEAVDTDAPCMQYNCTYVSVTPKLSNVATEWPQRSLLVPGNEVIFSLETASDYLTEYNKANNEENRFGFRCLAVGYEDSNLTSQKQGLVALEMDLMFTGAACASKLLAPDLEIPPMSFATLLEVQLQAMIGGNPTGGEDETPQDACETLFLSRGLDLTSLPTVHQIFDDQSLQQ

Description

Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (By similarity). Plays a key role in neural development, probably by mediating ubiquitination of threonine residues on target proteins (By similarity). Involved in different processes such as regulation of neurite outgrowth, synaptic growth, synaptogenesis and axon degeneration (By similarity). Required in the visual system for correct fasciculation, targeting and mapping of retinal axons (PubMed:15590740). Acts as a regulator of pteridine synthesis (PubMed:15617681). May play a role in the regulation of the circadian clock gene expression (By similarity).

Similarity

Belongs to the RING-Cys relay (RCR) family.

Keywords

Alternative splicing Biological rhythms Cell projection Complete proteome Cytoplasm Cytoskeleton Disulfide bond Guanine-nucleotide releasing factor Metal-binding Nucleus Reference proteome Repeat Transferase Ubl conjugation pathway Zinc Zinc-finger

Feature

chain E3 ubiquitin-protein ligase MYCBP2
splice variant In isoform 2.

Uniprot

H9JS28 A0A212EQK1 A0A194R389 A0A194PFI5 A0A195DKB5 A0A151JUZ3 + More
A0A195AUQ9 A0A158P184 A0A151WWB0 A0A0L7QXQ4 A0A0M8ZY59 A0A0J7KSE5 A0A1S3IPI7 A0A2T7PNH1 A0A210PHL2 A0A2D0R327 A0A2D0R582 A0A1S3PKZ8 A0A1W4Y975 A0A146RFE5 A0A1S3PLW2 A0A146R4G4 A0A146QW01 A0A146RHN8 A0A146RU14 A0A146R383 A0A146Q747 A0A146PH18 A0A146RIP1 A0A146RIS6 A0A146RHT9 A0A146RGN7 A0A226E6P2 A0A1A7ZKG4 A0A1A8A3F7 A0A1A7ZSG4 A0A1A8A2F5 A0A1A8UGH4 A0A1A7ZFN4 A0A1A8A4V0 A0A218V3P0 A0A1V4J4C6 A0A287D8T7 A0A2I4CBL4 A0A1A7YUK8 A0A0F8AUC4 A0A2I4CBK8 A0A287AXI4 A0A287BIQ1 A0A2Y9HUF8 A0A3L8E3R5 A0A151NKV4 A0A151NL08 A0A151NKV9 A0A151NL93 A0A151NKX4 F1NZF2 F1RD40-2 C3ZT14 A0A1A8ESD3 A0A1A8F3W7

EC Number

2.3.2.-

Pubmed

19121390 22118469 26354079 21347285 28812685 25835551 + More
30249741 22293439 15592404 15590740 23594743 20143133 15617681 18563158

EMBL

BABH01017124 BABH01017125 BABH01017126 BABH01017127 AGBW02013269 OWR43755.1 + More
KQ460953 KPJ10311.1 KQ459605 KPI92047.1 KQ980765 KYN13333.1 KQ981732 KYN36595.1 KQ976738 KYM75797.1 ADTU01005953 KQ982691 KYQ52184.1 KQ414699 KOC63392.1 KQ435797 KOX73500.1 LBMM01003612 KMQ93322.1 PZQS01000003 PVD34975.1 NEDP02076690 OWF35988.1 GCES01119191 JAQ67131.1 GCES01123415 JAQ62907.1 GCES01125944 JAQ60378.1 GCES01118726 JAQ67596.1 GCES01114756 JAQ71566.1 GCES01123414 JAQ62908.1 GCES01134213 JAQ52109.1 GCES01143297 JAQ43025.1 GCES01118061 JAQ68261.1 GCES01118060 JAQ68262.1 GCES01118725 JAQ67597.1 GCES01119192 JAQ67130.1 LNIX01000006 OXA53010.1 HADY01004050 SBP42535.1 HADY01010723 SBP49208.1 HADY01006425 SBP44910.1 HADY01010348 SBP48833.1 HAEJ01006967 SBS47424.1 HADY01002400 SBP40885.1 HADY01011051 HAEJ01002341 SBP49536.1 MUZQ01000057 OWK60576.1 LSYS01009367 OPJ66989.1 AGTP01036522 AGTP01036523 AGTP01036524 AGTP01036525 HADX01012060 SBP34292.1 KQ041047 KKF31069.1 AEMK02000077 QOIP01000001 RLU27103.1 AKHW03002722 KYO37441.1 KYO37440.1 KYO37442.1 KYO37439.1 KYO37438.1 AADN05000383 AY818192 AL731656 AL731859 AL840634 BX510646 CR628366 CU138551 GU299766 GU299767 GG666675 EEN44359.1 HAEB01003235 SBQ49762.1 HAEB01007508 SBQ54035.1

Proteomes

UP000005204 UP000007151 UP000053240 UP000053268 UP000078492 UP000078541 + More
UP000078540 UP000005205 UP000075809 UP000053825 UP000053105 UP000036403 UP000085678 UP000245119 UP000242188 UP000221080 UP000087266 UP000192224 UP000198287 UP000197619 UP000190648 UP000005215 UP000192220 UP000008227 UP000248481 UP000279307 UP000050525 UP000000539 UP000000437 UP000001554

PRIDE

H9JS28

Pfam

PF08005   PHR        + More
PF00415   RCC1
PF03256   ANAPC10
PF13639   zf-RING_2
PF08239   SH3_3
PF00630   Filamin

Interpro

IPR038648   PHR_sf        + More
IPR009091   RCC1/BLIP-II
IPR012983   PHR
IPR000408   Reg_chr_condens
IPR014756   Ig_E-set
IPR001841   Znf_RING
IPR013083   Znf_RING/FYVE/PHD
IPR004939   APC_su10/DOC_dom
IPR008979   Galactose-bd-like_sf
IPR017868   Filamin/ABP280_repeat-like
IPR003646   SH3-like_bac-type

SUPFAM

SSF50985   SSF50985        + More
SSF81296   SSF81296
SSF49785   SSF49785

Gene 3D

2.130.10.30 2.60.120.820 2.60.120.260 3.30.40.10

ProteinModelPortal

H9JS28 A0A212EQK1 A0A194R389 A0A194PFI5 A0A195DKB5 A0A151JUZ3 + More
A0A195AUQ9 A0A158P184 A0A151WWB0 A0A0L7QXQ4 A0A0M8ZY59 A0A0J7KSE5 A0A1S3IPI7 A0A2T7PNH1 A0A210PHL2 A0A2D0R327 A0A2D0R582 A0A1S3PKZ8 A0A1W4Y975 A0A146RFE5 A0A1S3PLW2 A0A146R4G4 A0A146QW01 A0A146RHN8 A0A146RU14 A0A146R383 A0A146Q747 A0A146PH18 A0A146RIP1 A0A146RIS6 A0A146RHT9 A0A146RGN7 A0A226E6P2 A0A1A7ZKG4 A0A1A8A3F7 A0A1A7ZSG4 A0A1A8A2F5 A0A1A8UGH4 A0A1A7ZFN4 A0A1A8A4V0 A0A218V3P0 A0A1V4J4C6 A0A287D8T7 A0A2I4CBL4 A0A1A7YUK8 A0A0F8AUC4 A0A2I4CBK8 A0A287AXI4 A0A287BIQ1 A0A2Y9HUF8 A0A3L8E3R5 A0A151NKV4 A0A151NL08 A0A151NKV9 A0A151NL93 A0A151NKX4 F1NZF2 F1RD40-2 C3ZT14 A0A1A8ESD3 A0A1A8F3W7

PDB

3GBW E-value=3.04527e-44, Score=456

KEGG

101743567 K10693 E3 ubiquitin-protein ligase MYCBP2 [EC:2.3.2.27] | (RefSeq) E3 ubiquitin-protein ligase MYCBP

GO

GO:0016874 GO:0021986 GO:0042068 GO:0005856 GO:0021952 GO:0005737 GO:0004842 GO:0008536 GO:0046872 GO:0005634 GO:0007411 GO:0048066 GO:0061630 GO:0016198 GO:1902667 GO:0032922 GO:0031290 GO:0050905 GO:0005085 GO:0030424

Subcellular location

Nucleus   Localizes to axon shafts and associates with microtubule cytoskeleton.   With evidence from 2 publications.
Cell projection   Localizes to axon shafts and associates with microtubule cytoskeleton.   With evidence from 2 publications.
Axon   Localizes to axon shafts and associates with microtubule cytoskeleton.   With evidence from 2 publications.
Cytoplasm   Localizes to axon shafts and associates with microtubule cytoskeleton.   With evidence from 2 publications.
Cytoskeleton   Localizes to axon shafts and associates with microtubule cytoskeleton.   With evidence from 2 publications.

Length:

2188

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0361400000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00027

outside

1 - 2188

Pi

33.19177

Theta

21.396629

Tajima's D

-1.481445

CLR

0.162593

CSRT

0.0616969151542423

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics