Gene

KWMTBOMO00532  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012267

Annotation

alpha-mannosidase_II_[Spodoptera_frugiperda]

Location

Bomo_Chr1(-):15479184-15508359      View in EpiBrowser

Full name

Alpha-mannosidase      

Location in the cell

Cytoplasmic   Reliability : 1.931 Nuclear   Reliability : 1.566

CDS

ATGCAGCGGACACCGAAATATAAAAAGGCACCCAGTCAGTGTCCAGTTCTCAAAGAAAGCGATGCTGACATTGACACCATGTCGCTGTATCCATCGTTCGAGTTCCAGCCGAGCTGGTTGCGCACAAAGGAATTCTGGGACAGGACCTTTGAGGAAAGATACGAGAAGATAAAGAACGATAGCCGTCGACCAAGACTTAAGGTGATCGTCGTGCCTCATTCTCACAATGACCCGGGATGGCTGAAGACCTTCGAGCACTACTTCGAATGGAAAACCAAAAACATCATCAACAACATAGTGCAGAAATTACATCAGTACCCGAACATGACTTTCATCTGGACTGAGATATCGTTCCTCAACTCTTGGTGGGAAAGGTCTCATCCCATTAAGCAAAAGGCATTAAAGAAACTCATAAAAGAAGGACGCCTGGAGATCACAACTGGCGGCTGGGTGATGCCCGATGAAGCTTGCACTCATATTTACGCGTTGGTTGATCAGTTCATTGAAGGTCATCACTGGGTGAAAACCAACCTCGGTATAGTTCCCAAAACCGGTTGGTCCATCGACCCCTTCGGTCACGGCCCAACTGTACCTTACATATTGGACAAAAGCGGGTTAGAAGGAACCATAATTCAGAGGATTCATTACGCGTGGAAACAATGGTTCGCTCAACGGCAGATCGAGGAATTCTACTGGATCACTGGCTGGAAGTCAAAAAAGCCAACGATGATCGTTCACAACCAACCTTTCGACATATATTCTATAAAGAGCACGTGCGGCCCTCATCCCTCGATCTGTCTCAGTTTCGATTTCAGAAAGATTCCCGGCGAGTATTCCGAATACACCGCCAAACACGAGGACATTACTGAACAAAATCTCCACTCCAAATCGAAAACGTTAATAGAGGAATACGATCGCATCGGTTCGTTGACTACCCACAACGTGGTCCTGGTGCCGCTGGGCGACGACTTCCGATACGATTACGACATCGAATTCGACGCCCAATACATCAATTACATGAAAATGTTCAATTACATTAACGGCCACAAGGAACTATTCAACGCTGATGTTCAATTCGGCACTCCTTTGGACTATTTCAATGCGATGAAAGAACGTCAATCCGATATTCCGACGCTGAAAGGAGATTTCTTCGTTTACTCCGATATATTTAGCGAAGGTAAGCCAGCTTATTGGTCCGGGTATTACACCACACGACCGTATTTAAAGATCCTCACGCGGCAGCTGGAACATCAACTTCGTACCGCAGAAATATTATTCACCCTGAAGAAACTTGAAAAGTCATATGAGAACCTGATCACCGCGAGGCGAAACTTAGGTCTCTTCCAGCATCACGACGCTATTACTGGGACATCGAAATCTGCTGTTATGCAGGACTACGGCACCAAATTGTTCACGAGCATCAACCACTGCATTCGGCTGCAGGAGACCGCCCTTACTACTATAATGGTTCCAGACGAAACCCTGCACGGACAGAATATCATACAAAGCGAAATGGAATGGGAAACATACGGAAAACCAATCAAGAAACTACAAGTATCATATGTGGACAAGAAGAAAGTTATCCTGTTCAATCCCCTAGTCGAGAGCAGAACTGAAATCATAACGCTCTCCTCAAACACAACTAATGTTCGAGTTTACGATACGAGACAAGGCAAGCACGTGCAATATCAGATCGCGCCTAATATAGACGTACACGAAGACGGAAAACGCGTCATAAGCGACACCAACTTTGACATAACGTTTGTGGCAACACTCCCGCCGCTCACCTCGGTCACTTTCAATCTCGAAGAGCACGTCGGTGTGGCTAACCACTGCGTTGTGTTCTGTAACAGCTGCAACGATAAATCGGACGGCGAAAGTCTATTCGTAACGAAGAAAATGATGCCCGGAGACATTCAACTGGAGAACTCTGTGCTAAAGCTATTGATTAACAGGCACACCGGCTTCCTTAGACAGATATACAGAAAAGACGTTTATAAAAAGAACGTTGTCGAAATGCAATTCGGTGCATATCAGAGCGCCCAGAGACACTCTGGAGCGTATCTGTTTATGCCCGATTACGATTCTCCAGAGAAGAACGTTCTGAACACATACTCGAACTGGGACAAACAATCCGAAGACAACATTATTATCGTTTCCGGTCCCGTATCGCGGGAGATCACGATTATGTATTTGCCGTTCCTCATACACACAATTAAGATTTTTGACGTCGACGATCCGATACTGTCCCGAGCGGTGCTCGTCGAAAACATAGTAGATTTCGAGGATCCACCAAAGAACCGAGACACAGAACTTTTTATGAGAATTCAAACCGACATACAGAACGGCGAACCGCCCGAATTCTACACCGACCAGAACGGCTTTCAATATCAGAAACGTACAAAAATCGATAAGCTTGGCATCGAAGCTAATTATTATCCTATCACGACTATGGCTTGGATGCAGGACAAAGAAACGAGACTGACTTTGATTACTAATCACGCGCAGGGAGCCGCCTCATACGAACCGGGGCGCTTGGAAGTGATGCTCGATAGACGCACGCTCTACGACGATTTTAGAGGCATCGGCGAAGGAGTGGTCGACAATAAGCCCACCACATTCCAAAACTGGCTCCTACTGGAGACGATGCCTGGGGCACGAATCGGAAAAGACAACACTGATTCTATGAACACGAGAAACTTTAGTCCAGAACAGAAGACTAACCATTATGAGTTGCCTTCTCACTCAGCCGACTATTTGAGCAGAACCTTCAATTATCCAGTCAACGTATACCTTTTGGATACTAGCGAAATGGGAGAAGTGGCTATCAAGTCGTCTCAAACGTTCGTGGAGAACTTCCCTAACGGCATACATTTGGTGACACTCCGGACCATAACCGACGACGTCTTAGAACAGTTCCCCAGTACATCGAGCTACATGGTCTTGCAGAGACCGGGTTATTCCTGTACTATCGGTAAATTCTCAAAACGAGTTCCCAGTTTTAATTCGAAATCGAAATTTAGCGGACTCATCATCAACAACTTGACTTCAGTCAGTTTGACGGGTCTAAAAACCTACCAGCACCTGTACGACTTAGAAGACATCGAACTTGAACCGATGGAGGTGAAGACGTACAAAATCAAGTTCTAA

Protein

MQRTPKYKKAPSQCPVLKESDADIDTMSLYPSFEFQPSWLRTKEFWDRTFEERYEKIKNDSRRPRLKVIVVPHSHNDPGWLKTFEHYFEWKTKNIINNIVQKLHQYPNMTFIWTEISFLNSWWERSHPIKQKALKKLIKEGRLEITTGGWVMPDEACTHIYALVDQFIEGHHWVKTNLGIVPKTGWSIDPFGHGPTVPYILDKSGLEGTIIQRIHYAWKQWFAQRQIEEFYWITGWKSKKPTMIVHNQPFDIYSIKSTCGPHPSICLSFDFRKIPGEYSEYTAKHEDITEQNLHSKSKTLIEEYDRIGSLTTHNVVLVPLGDDFRYDYDIEFDAQYINYMKMFNYINGHKELFNADVQFGTPLDYFNAMKERQSDIPTLKGDFFVYSDIFSEGKPAYWSGYYTTRPYLKILTRQLEHQLRTAEILFTLKKLEKSYENLITARRNLGLFQHHDAITGTSKSAVMQDYGTKLFTSINHCIRLQETALTTIMVPDETLHGQNIIQSEMEWETYGKPIKKLQVSYVDKKKVILFNPLVESRTEIITLSSNTTNVRVYDTRQGKHVQYQIAPNIDVHEDGKRVISDTNFDITFVATLPPLTSVTFNLEEHVGVANHCVVFCNSCNDKSDGESLFVTKKMMPGDIQLENSVLKLLINRHTGFLRQIYRKDVYKKNVVEMQFGAYQSAQRHSGAYLFMPDYDSPEKNVLNTYSNWDKQSEDNIIIVSGPVSREITIMYLPFLIHTIKIFDVDDPILSRAVLVENIVDFEDPPKNRDTELFMRIQTDIQNGEPPEFYTDQNGFQYQKRTKIDKLGIEANYYPITTMAWMQDKETRLTLITNHAQGAASYEPGRLEVMLDRRTLYDDFRGIGEGVVDNKPTTFQNWLLLETMPGARIGKDNTDSMNTRNFSPEQKTNHYELPSHSADYLSRTFNYPVNVYLLDTSEMGEVAIKSSQTFVENFPNGIHLVTLRTITDDVLEQFPSTSSYMVLQRPGYSCTIGKFSKRVPSFNSKSKFSGLIINNLTSVSLTGLKTYQHLYDLEDIELEPMEVKTYKIKF

Cofactor

Zn(2+)

Similarity

Belongs to the glycosyl hydrolase 38 family.

Feature

chain  Alpha-mannosidase

Uniprot

H9JRV7   A0A2A4JK36   A0A2H1UZM9   O18497   A0A194QU43   A0A0L7KXH8   + More
A0A212EKL4   V5GSP3   A0A1Y1LCP1   D6WL14   K7J217   U4UKH6   A0A0L7QSR0   A0A195FBG3   A0A182VWZ9   A0A084VTK8   A0A182IYJ7   A0A158NN37   A0A2M4DLZ4   A0A2M4CUG3   A0A182RSL1   B0W928   A0A2M4DN40   A0A2M4CV25   A0A182MDZ9   Q17CX9   A0A0C9R7P1   A0A087ZYA7   A0A182NG26   W8BKY7   A0A151J3Q1   A0A151WLE3   A0A182P433   E2AJT2   A0A195C452   A0A034V2M0   A0A182XFD6   A0A0A1X9U7   A0A182UTI2   A0A182I866   A0A195BUS9   A0A0K8WFL5   Q7QH78   N6TME6   A0A067QNP3   A0A336MSP4   A0A182K4H2   A0A1I8QCR4   A0A336KIY3   A0A1I8N8G6   A0A0L0CGC9   A0A0M4EHK4   A0A1B6CP65   B4JFC9   A0A1J1J1Q3   A0A182QXU0   A0A224X650   B4NK70   A0A1B6G5M0   A0A2R7VP32   A0A154PDG0   A0A1B0G6Q7   A0A0K8TAV1   A0A182TH94   A0A1A9W1L9   A0A1B6LLU3   A0A1B0BKC5   B3P3V5   B4M4C9   R4WDK2   A0A0R1E378   A0A1A9ZRU0   B4PRK6   A0A0R1E7A3   Q9VF33   B4HLW4   O97043   Q75WP2   B4QXU7   A0A1W7R8I3   B3M376   A0A3B0JN03   B4K676   A0A1W4VRU5   E0VA20   A0A1W4VQH8   A0A2H8TN46   A0A2S2PS58   Q296D2   A0A0R3NNN2   A0A0R3NIG7   A0A2S2QQ97   A0A182FA32   A0A026W2F1   J9JLY2   T1HKR4   A0A2A3EFY6   A0A182SX67   A0A0P4VQU2   A0A182YG08  

EC Number

3.2.1.-

Pubmed

19121390    9061370    26354079    26227816    22118469    28004739    + More
18362917    19820115    20075255    23537049    24438588    21347285    17510324    24495485    20798317    25348373    25830018    12364791    14747013    17210077    24845553    25315136    26108605    17994087    26823975    18057021    23691247    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20566863    15632085    23185243    24508170    27129103    25244985   

EMBL

BABH01017048    NWSH01001311    PCG71762.1    ODYU01000013    SOQ34068.1    AF005034    + More
AAB62719.1    KQ461108    KPJ08992.1    JTDY01004592    KOB67973.1    AGBW02014274    OWR41988.1    GALX01003834    JAB64632.1    GEZM01063078    GEZM01063077    GEZM01063076    GEZM01063075    JAV69326.1    KQ971343    EFA04051.1    KB632365    ERL93622.1    KQ414756    KOC61677.1    KQ981693    KYN37562.1    ATLV01016361    KE525079    KFB41302.1    ADTU01020975    ADTU01020976    ADTU01020977    ADTU01020978    ADTU01020979    ADTU01020980    ADTU01020981    ADTU01020982    ADTU01020983    ADTU01020984    GGFL01014381    MBW78559.1    GGFL01004808    MBW68986.1    DS231861    EDS39467.1    GGFL01014380    MBW78558.1    GGFL01005026    MBW69204.1    AXCM01002744    AXCM01002745    AXCM01002746    CH477302    EAT44226.1    GBYB01012378    GBYB01012379    GBYB01012380    GBYB01012382    JAG82145.1    JAG82146.1    JAG82147.1    JAG82149.1    GAMC01016292    GAMC01016291    JAB90264.1    KQ980262    KYN17069.1    KQ982993    KYQ48505.1    GL440100    EFN66248.1    KQ978344    KYM94956.1    GAKP01022218    JAC36734.1    GBXI01006430    GBXI01004884    JAD07862.1    JAD09408.1    APCN01002657    KQ976406    KYM91677.1    GDHF01010178    GDHF01002353    JAI42136.1    JAI49961.1    AAAB01008817    EAA05368.5    APGK01018545    KB740080    ENN81639.1    KK853117    KDR11149.1    UFQT01002444    SSX33472.1    UFQS01000467    UFQT01000467    SSX04251.1    SSX24616.1    JRES01000503    KNC30549.1    CP012526    ALC45871.1    GEDC01022193    JAS15105.1    CH916369    EDV93410.1    CVRI01000066    CRL06327.1    AXCN02001199    GFTR01008500    JAW07926.1    CH964272    EDW85112.1    GECZ01029738    GECZ01012040    JAS40031.1    JAS57729.1    KK854006    PTY09119.1    KQ434868    KZC09230.1    CCAG010008178    GBRD01003172    GDHC01017230    JAG62649.1    JAQ01399.1    GEBQ01015276    JAT24701.1    JXJN01015891    CH954181    EDV49061.1    CH940652    EDW59490.1    KRF78889.1    AK417599    BAN20814.1    CM000160    KRK03728.1    EDW97406.1    KRK03729.1    AE014297    BT150367    AAF55228.2    AGB95994.1    AGW52177.1    CH480815    EDW42001.1    AB018079    BAA75817.1    AB120954    BAC92711.1    CM000364    EDX12771.1    GEHC01000189    JAV47456.1    CH902617    EDV43537.1    KPU80303.1    OUUW01000007    SPP83615.1    CH933806    EDW14126.2    DS235004    EEB10226.1    GFXV01003605    MBW15410.1    GGMR01019681    MBY32300.1    CM000070    EAL28526.3    KRT00789.1    KRT00792.1    GGMS01010099    MBY79302.1    KK107467    EZA50257.1    ABLF02027081    ABLF02027082    ACPB03000921    KZ288266    PBC30129.1    GDKW01003077    JAI53518.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000037510    UP000007151    UP000007266    + More
UP000002358    UP000030742    UP000053825    UP000078541    UP000075920    UP000030765    UP000075880    UP000005205    UP000075900    UP000002320    UP000075883    UP000008820    UP000005203    UP000075884    UP000078492    UP000075809    UP000075885    UP000000311    UP000078542    UP000076407    UP000075903    UP000075840    UP000078540    UP000007062    UP000019118    UP000027135    UP000075881    UP000095300    UP000095301    UP000037069    UP000092553    UP000001070    UP000183832    UP000075886    UP000007798    UP000076502    UP000092444    UP000075902    UP000091820    UP000092460    UP000008711    UP000008792    UP000002282    UP000092445    UP000000803    UP000001292    UP000000304    UP000007801    UP000268350    UP000009192    UP000192221    UP000009046    UP000001819    UP000069272    UP000053097    UP000007819    UP000015103    UP000242457    UP000075901    UP000076408   

PRIDE

H9JRV7    Q9VF33    O97043    Q75WP2   

Pfam

PF09261   Alpha-mann_mid        + More
PF07748   Glyco_hydro_38C
PF01074   Glyco_hydro_38N
PF00173   Cyt-b5

Interpro

IPR000602   Glyco_hydro_38_N        + More
IPR011330   Glyco_hydro/deAcase_b/a-brl       
IPR011013   Gal_mutarotase_sf_dom       
IPR015341   Glyco_hydro_38_cen       
IPR027291   Glyco_hydro_38_N_sf       
IPR037094   Glyco_hydro_38_cen_sf       
IPR013780   Glyco_hydro_b       
IPR011682   Glyco_hydro_38_C       
IPR028995   Glyco_hydro_57/38_cen_sf       
IPR036612   KH_dom_type_1_sf       
IPR036400   Cyt_B5-like_heme/steroid_sf       
IPR001199   Cyt_B5-like_heme/steroid-bd       

SUPFAM

SSF88688   SSF88688        + More
SSF88713   SSF88713       
SSF74650   SSF74650       
SSF54791   SSF54791       
SSF55856   SSF55856       

Gene 3D

1.20.1270.50     2.60.40.1180     3.20.110.10     3.10.120.10     3.30.1370.10    

ProteinModelPortal

H9JRV7   A0A2A4JK36   A0A2H1UZM9   O18497   A0A194QU43   A0A0L7KXH8   + More
A0A212EKL4   V5GSP3   A0A1Y1LCP1   D6WL14   K7J217   U4UKH6   A0A0L7QSR0   A0A195FBG3   A0A182VWZ9   A0A084VTK8   A0A182IYJ7   A0A158NN37   A0A2M4DLZ4   A0A2M4CUG3   A0A182RSL1   B0W928   A0A2M4DN40   A0A2M4CV25   A0A182MDZ9   Q17CX9   A0A0C9R7P1   A0A087ZYA7   A0A182NG26   W8BKY7   A0A151J3Q1   A0A151WLE3   A0A182P433   E2AJT2   A0A195C452   A0A034V2M0   A0A182XFD6   A0A0A1X9U7   A0A182UTI2   A0A182I866   A0A195BUS9   A0A0K8WFL5   Q7QH78   N6TME6   A0A067QNP3   A0A336MSP4   A0A182K4H2   A0A1I8QCR4   A0A336KIY3   A0A1I8N8G6   A0A0L0CGC9   A0A0M4EHK4   A0A1B6CP65   B4JFC9   A0A1J1J1Q3   A0A182QXU0   A0A224X650   B4NK70   A0A1B6G5M0   A0A2R7VP32   A0A154PDG0   A0A1B0G6Q7   A0A0K8TAV1   A0A182TH94   A0A1A9W1L9   A0A1B6LLU3   A0A1B0BKC5   B3P3V5   B4M4C9   R4WDK2   A0A0R1E378   A0A1A9ZRU0   B4PRK6   A0A0R1E7A3   Q9VF33   B4HLW4   O97043   Q75WP2   B4QXU7   A0A1W7R8I3   B3M376   A0A3B0JN03   B4K676   A0A1W4VRU5   E0VA20   A0A1W4VQH8   A0A2H8TN46   A0A2S2PS58   Q296D2   A0A0R3NNN2   A0A0R3NIG7   A0A2S2QQ97   A0A182FA32   A0A026W2F1   J9JLY2   T1HKR4   A0A2A3EFY6   A0A182SX67   A0A0P4VQU2   A0A182YG08  

PDB

1PS3     E-value=9.38347e-137,     Score=1251

KEGG

101746737    K01191 alpha-mannosidase [EC:3.2.1.24] | (RefSeq) alpha-mannosidase 2-like

PATHWAY

00511    Other glycan degradation - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0030246   GO:0004559   GO:0006013   GO:0016021   GO:0006491   GO:0006517   GO:0000139   GO:0004571   GO:0035010   GO:0016063   GO:0052767   GO:0003723   GO:0012505   GO:0004553   GO:0008270   GO:0005975   GO:0003824   GO:0015923   GO:0007169  

Length:

1049

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0186

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00086

outside

1  -  1049

 

 

Pi

21.678511

Theta

26.622114

Tajima's D

-0.936663

CLR

0.075924

CSRT

0.148042597870106

Interpretation

Uncertain