Gene

KWMTBOMO00516

Pre Gene Modal

BGIBMGA012277

Annotation

Protein_SERAC1_[Operophtera_brumata]

Location

Bomo_Chr1(-):15119728-15122189      View in EpiBrowser

Full name

GPI inositol-deacylase      

Location in the cell

Mitochondrial   Reliability : 1.67 Nuclear   Reliability : 1.218

CDS

ATGAGCCTGCAAGACAGACTAAAGCCCATTTTGAAAATACTAAAATTTACATCAATTTGGGGAGGTGGTGGAATTTTTTTTGCTTATCATGTCAGTCAGACGTACAAAACAGTAGACAAGATCGTAAACACAAAAGTTCTAGATCGTGAAAAGAAACATACCCCAGAATATATTTACATTGACGACCCTTCATACAGCATCACATTAAAAAGGGAACAAGACAAAGAATCTAGACGGTCTATAGGTCTCTCGCGAGTTTGGAAGAGTCTGAAGCATTCTTTAGCATGGCGTCTTTTGTGGTTATGTCGTCACGGGAACAAGGAGCAGCGTAACATAGCTCTGAAACAGCTAGCTGCTTTCAAAAACAATAAGATTTGGGACTGTCAAAAACTCGCTCAAGCTTTAGACATGAACACAGCCGTCTTGCTAGCAAGAACTCGCGGTGCTGATCTACGGTACTTCCTCCCTCCGCCTATACATGTACGTAGAGCCGCATTAACTTCTGAATTACTCTCTTTCAAATTCCGAGACATGATACTTTCTGTTCAAGGAGTCCATCCACACAGTTGTATTCAACATTTCCTATCGAAATATTTTGCCAATATTCAGGAACAGGCCTTAGAAGCAGATAATATTCCCGCAAAGCCAGATAGTATTAGTGAGAGAGATTTGTGTATTTTGTGTCTTGATGCCCTCTATCACCACATCAGTCTTTTTCATGTTAACGATTATGAAGATGATGATTCTATAAAAACTCTTATAAAAATGGGACTCCTTCCAAGATTAGCTGAGTTAATGTTAAGAGAGCGCGATGACACTGATTTGGATTTGGCTGTACTTAAAATACTCACTGTTCTGAGTGTTCATTGTAATTTATTATTAGATTTTTTTCAAAACGGTCTTATAAAAGAGTTGTCTCGGCTCCTTAGATCAAAAGATGTGCGATTGGCAAGTTCTGCTGCAGTTTGTTTAGCAAATTTATCAGGGGAACATTGTTACAGACCAGGACTGTACTTGTTGCACCCATTGTATCGAACTACAGTTGCACCAACATGTGACACTCTTCTAGTGCACGGCCTCAGAGGTGGTGTTTTTGTCACATGGCGACAGAGAGATAAAAAGTGCGCTGAACCTCTTGGAATTGTTGAAGGAACAATATCCGATGTTGACTGTGATCCCTGCGAAGAAAAATCAATCGATACAAAGTATCTTGACCCAGATTTGCAACAAGTAATGGATGATCTGATAGAATTAGATGATGAAACTCTGTTGTCTGACTTAGAAGTAGTTTTACATGACCTCCCTATTGAGGCAAAGCGAGAACCTTTGAATACTAATATTTACACTATAAGTAAGAAACGCATAGCCCTTATGCAGGAAGAAGAGGATCAATGTAATTATACATTTTGTTGGCCTAAAGATTGGCTACCTAAAGACTGCAATAATTTGAGAATATTAGGTATCAATTATTGGAGCTCAATATCTGAATGGCTAGAACGATGCCCCCTACAGACAGCTGACATATCAACCAAGGCTTCAGAATTAGGTCCTACATTAGTTGATGCTGGTGTCGGAAGAAAAGGTACTCCTGTTGTGTGGTTAGCTCATTCCATGGGAGGGCTTATAGTTAAACAAGTACTCATTGACTCTGCTCAAAGTAGTGATGACAAATTTAAAAGGCTTTCAAGGAATACTAAGGCTGTATTGTTTTATAGTACACCTCATAAAGGTAGTGCACTTGCGACTATGCCAAGGGCTGCAGCTGCTGTGCTGTGGCCTTCAAACGATGTGCGTCAGTTACAAGAAAACTCGCCAGTTTTACTTGAACTGCATAGAGCATTCATACACGCAGCTGAACAATACCAATGGGAGACCATAAGTTTTGCTGAAATGATGCCAACTTTGGTTACAACATTTAAAGTACCAATCCACTTTGTAGAAGCTTATTCTGCAGACTTAGGACGAGGTGTGTTTTATCAGTTACCTTTAGATCATCTGTCTATATGTAAGCCGGCCACGAGACAATCAATACTGTATACAACAGTCCTGGATGTAATACAAAGGGTGACTGCCAGAAATATTGAAATAAAATACTCTGATTCCCTTATAAAATGGATTATTGACATGCTTTGGTGGACTCTGAGGACAAAAACTAATGAGGCTATAGAAAAAGTTGATGAAGCTCAAAGAATTGAAGGTCTTCGTTGGTATGAGCGAGTCCTACTCGACACATTTACTGATGGATTTACAGATTAG

Protein

MSLQDRLKPILKILKFTSIWGGGGIFFAYHVSQTYKTVDKIVNTKVLDREKKHTPEYIYIDDPSYSITLKREQDKESRRSIGLSRVWKSLKHSLAWRLLWLCRHGNKEQRNIALKQLAAFKNNKIWDCQKLAQALDMNTAVLLARTRGADLRYFLPPPIHVRRAALTSELLSFKFRDMILSVQGVHPHSCIQHFLSKYFANIQEQALEADNIPAKPDSISERDLCILCLDALYHHISLFHVNDYEDDDSIKTLIKMGLLPRLAELMLRERDDTDLDLAVLKILTVLSVHCNLLLDFFQNGLIKELSRLLRSKDVRLASSAAVCLANLSGEHCYRPGLYLLHPLYRTTVAPTCDTLLVHGLRGGVFVTWRQRDKKCAEPLGIVEGTISDVDCDPCEEKSIDTKYLDPDLQQVMDDLIELDDETLLSDLEVVLHDLPIEAKREPLNTNIYTISKKRIALMQEEEDQCNYTFCWPKDWLPKDCNNLRILGINYWSSISEWLERCPLQTADISTKASELGPTLVDAGVGRKGTPVVWLAHSMGGLIVKQVLIDSAQSSDDKFKRLSRNTKAVLFYSTPHKGSALATMPRAAAAVLWPSNDVRQLQENSPVLLELHRAFIHAAEQYQWETISFAEMMPTLVTTFKVPIHFVEAYSADLGRGVFYQLPLDHLSICKPATRQSILYTTVLDVIQRVTARNIEIKYSDSLIKWIIDMLWWTLRTKTNEAIEKVDEAQRIEGLRWYERVLLDTFTDGFTD

Description

Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

Similarity

Belongs to the GPI inositol-deacylase family.

Uniprot

H9JRW7   A0A0L7L078   A0A2A4JE37   A0A2H1VCF9   A0A194QU20   A0A194PL50   + More
A0A212EIE5   A0A2J7Q0Y4   A0A2J7Q0X1   A0A067QU96   K7IRT0   A0A232FF61   A0A158ND75   A0A2A3ENP0   A0A151WG90   E9J2D1   A0A087ZZG8   A0A0L7QNP2   A0A195B1B6   A0A2J7Q0Y8   A0A0J7NRW5   A0A195DKA7   A0A151I8R0   A0A195FHN0   A0A2M4CPW0   A0A2M4A0Q7   A0A154PQ71   E2A031   F4X787   A0A2M3ZG89   A0A3L8D3K6   A0A310SPK4   A0A1Y1LZ43   A0A182GCC9   A0A1Q3FEG5   A0A139WN90   A0A0M9A4Y0   B0W7Z2   A0A026WXE3   U5EDY0   A0A2M4A0Y5   T1E1U1   A0A2M4A0N7   A0A2P8XKB0   U4U596   A0A2R7W0M9   A0A2J7Q0X2   A0A2H8TF92   J9JL18   E0VG14   A0A2S2QD03   B3MM44   T1H7Y1   A0A2J7Q0V6   A0A2J7Q0Y0   N6SXA2  

EC Number

3.1.-.-

Pubmed

19121390    26227816    26354079    22118469    24845553    20075255    + More
28648823    21347285    21282665    20798317    21719571    30249741    28004739    26483478    18362917    19820115    24508170    24330624    29403074    23537049    20566863    17994087   

EMBL

BABH01017024    JTDY01004017    KOB68706.1    NWSH01001921    PCG69672.1    ODYU01001792    + More
SOQ38476.1    KQ461108    KPJ09028.1    KQ459605    KPI91830.1    AGBW02014676    OWR41240.1    NEVH01019960    PNF22235.1    PNF22233.1    KK852945    KDR13447.1    NNAY01000331    OXU29160.1    ADTU01012470    ADTU01012471    KZ288212    PBC32816.1    KQ983185    KYQ46852.1    GL767845    EFZ13006.1    KQ414855    KOC60106.1    KQ976690    KYM78080.1    PNF22236.1    LBMM01002178    KMQ95175.1    KQ980800    KYN12914.1    KQ978338    KYM95025.1    KQ981560    KYN39893.1    GGFL01003169    MBW67347.1    GGFK01001010    MBW34331.1    KQ435034    KZC14051.1    GL435543    EFN73214.1    GL888828    EGI57699.1    GGFM01006752    MBW27503.1    QOIP01000014    RLU14829.1    KQ761906    OAD56460.1    GEZM01048952    JAV76247.1    JXUM01009077    KQ560275    KXJ83384.1    GFDL01009095    JAV25950.1    KQ971312    KYB29402.1    KQ435732    KOX77317.1    DS231856    EDS38454.1    KK107070    EZA60692.1    GANO01004548    JAB55323.1    GGFK01000977    MBW34298.1    GALA01001765    JAA93087.1    GGFK01001055    MBW34376.1    PYGN01001864    PSN32433.1    KB631665    ERL85140.1    KK854169    PTY12490.1    PNF22231.1    GFXV01000905    MBW12710.1    ABLF02034499    DS235131    EEB12320.1    GGMS01006421    MBY75624.1    CH902620    EDV30859.1    ACPB03025021    PNF22232.1    PNF22234.1    APGK01053205    KB741222    ENN72409.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000053240    UP000053268    UP000007151    + More
UP000235965    UP000027135    UP000002358    UP000215335    UP000005205    UP000242457    UP000075809    UP000005203    UP000053825    UP000078540    UP000036403    UP000078492    UP000078542    UP000078541    UP000076502    UP000000311    UP000007755    UP000279307    UP000069940    UP000249989    UP000007266    UP000053105    UP000002320    UP000053097    UP000245037    UP000030742    UP000007819    UP000009046    UP000007801    UP000015103    UP000019118   

PRIDE

H9JRW7   

Pfam

PF03188   Cytochrom_B561        + More
PF10191   COG7
PF07819   PGAP1

Interpro

IPR029058   AB_hydrolase        + More
IPR000225   Armadillo       
IPR011989   ARM-like       
IPR016024   ARM-type_fold       
IPR006593   Cyt_b561/ferric_Rdtase_TM       
IPR019335   COG7       
IPR012908   PGAP1-like       

SUPFAM

SSF53474   SSF53474        + More
SSF48371   SSF48371       

Gene 3D

1.25.10.10     3.40.50.1820    

ProteinModelPortal

H9JRW7   A0A0L7L078   A0A2A4JE37   A0A2H1VCF9   A0A194QU20   A0A194PL50   + More
A0A212EIE5   A0A2J7Q0Y4   A0A2J7Q0X1   A0A067QU96   K7IRT0   A0A232FF61   A0A158ND75   A0A2A3ENP0   A0A151WG90   E9J2D1   A0A087ZZG8   A0A0L7QNP2   A0A195B1B6   A0A2J7Q0Y8   A0A0J7NRW5   A0A195DKA7   A0A151I8R0   A0A195FHN0   A0A2M4CPW0   A0A2M4A0Q7   A0A154PQ71   E2A031   F4X787   A0A2M3ZG89   A0A3L8D3K6   A0A310SPK4   A0A1Y1LZ43   A0A182GCC9   A0A1Q3FEG5   A0A139WN90   A0A0M9A4Y0   B0W7Z2   A0A026WXE3   U5EDY0   A0A2M4A0Y5   T1E1U1   A0A2M4A0N7   A0A2P8XKB0   U4U596   A0A2R7W0M9   A0A2J7Q0X2   A0A2H8TF92   J9JL18   E0VG14   A0A2S2QD03   B3MM44   T1H7Y1   A0A2J7Q0V6   A0A2J7Q0Y0   N6SXA2  

KEGG

101741411    K23504 protein SERAC1 | (RefSeq) protein SERAC1

GO

GO:0016021   GO:0055114   GO:0006890   GO:0006886   GO:0017119   GO:0007030   GO:0015031   GO:0016788   GO:0008340   GO:0005789   GO:0005488   GO:0005515   GO:0004713   GO:0005524   GO:0003677   GO:0003707   GO:0007169  

PANTHER

PTHR21443  

Subcellular location

Endoplasmic reticulum membrane  

Length:

751

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

8.85017999999996

Exp number, first 60 AAs:

8.71722

Total prob of N-in:

0.41764

outside

1  -  751

 

 

Pi

0.444541

Theta

1.711649

Tajima's D

-1.649947

CLR

0.000511

CSRT

0.031598420078996

Interpretation

Possibly Positive selection