Gene

KWMTBOMO00438  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000481

Annotation

Sulfhydryl_oxidase_1_[Papilio_machaon]

Location

Bomo_Chr1(-):12918941-12920844      View in EpiBrowser

Full name

Sulfhydryl oxidase      

Location in the cell

PlasmaMembrane   Reliability : 1.945

CDS

ATGAATTTCTGGTATACGTCTATTTTTGAAATATTTTTGATAGCTCTCGTTACGGGAGCAGTTGTGCCCACAACCGACGATGTAGACGAACAAGGATTGTACCGTAAGTCAGATCAAGTCGAAATCTTGACTAATAAAAATTTCGAAAAGAAATTATACGGCCAAAATAATGCTCTGTTGGTTCAGTTTTATAATAGTTACTGCGGTCATTGCCGAGCGTTTTCACCGAAATATAAAGCACTCGCATCTGACATAGCTCGTTGGAAAAAAGTTATTAAGTTAGCTGTTATTGATTGTTTTGTTGAAGAAAATAGTGAAATATGTAGACAATTTGAAGTAATGGCATACCCTTCCATACGATACTTCCACGAAAATTATATGAAGAGCAACTCAAATGTTGGAGAAAAAATGAACATTGCGGATACCGCAGAAAGACTTAAAAATCAATTGATTATAAAATTACAGGCAGAACAATCTATGGGACGTCTAATAATTGCTCCATCATTTAAGATTGAATCATATACATCCTATGCATCTGCATTACAAAGTGTACCTGGTGACATTGACTACATATTTTTAGTATTTGAAAATGATAATTCAACTATTGGATCACAAATAGCTTTAGATGTTGTTGACTATAAAAAAGTGAGAGTTAAGAGAGTATATGAAAATAGTGAATTAGCTCAAGTTGCTGGAGTTAAAAAAATTCCAAGTGTAGTTGCTCTAGAAAATAATTTACAAGCCACATTACTAACACCCAAACAGCCCACTGCACAAAATATATTAGAAGAGATAGATAGATTTTTGAAATCAAAAAATTATGTCTTTCCTCCGAAATATGCCAACATGAATGATATCAGTGATAGTTCTCAACAGAGAACATTTGTGCCAACCTCTGATGTTGCATACTATAATGATCTAGAAAAAACTTTAAAGGCAAGCTTGCACACTGAAATCACAAGGCACAAAACATTAACAGGTGAACCATTGCAGGCTTTATTAGACTACTTGGATGTTATTAAAACTTCGTTTCCATTTAGAGCCAATCTTGGAGAATATATAATGGACTTACATGCTACTTTAGCAGCAAGAAACAGCTGGACAGGTGGTGAAGTCTATGATTTAGTAAAAAGACTAGAAACTGCTCATGAACCAGTTTATATTACTAATTTAGAGTATGTTGGATGCAAAGGAAGTGAACCTAAATACAGAGGTTATACATGTGGACTGTGGACATTGTTCCATACTCTGACAGTCAACGCAGCACAAAAACCAGGTTCTGAAGGACCTAAAGTTCTTAAAGCAATGCATGGATATGTCAAAAACTTCTTTGGGTGTACTGAATGTGCTTCACATTTTCAAGCAATGGCAGCACGTAACAGAATATTTGATGTCAAAGAGAATAATAAAGCGGTTTTGTGGCTTTGGATTTCTCATAATGAAGTAAACCTTAGACTTGCGGGTGATGTCACAGAAGACCCTGAACATCCGAAAATTCAGTTTCCCAGTGCCACTAAATGCCCTGAATGCAGACTAGCTCAAGGAGCATGGAATCTAGTAGCAGTGTATGACTATCTTCAAAAGATGTATGGTGCCAACAACATCAAAGATGTAAGAAGAGCACAAGTGTCATCTGCTTCCAGCACCTTCTCCAATTTGGACATCGGGATGTTAAGTCTTTTGTACATATTATCTTTTATTTTCATTATTTTGGTTATAAAATACTTTTGGTCTAAACGTTTCTATAGAAAAAGACATTATAAAATGGGAATGGGCAAAGTATAG

Protein

MNFWYTSIFEIFLIALVTGAVVPTTDDVDEQGLYRKSDQVEILTNKNFEKKLYGQNNALLVQFYNSYCGHCRAFSPKYKALASDIARWKKVIKLAVIDCFVEENSEICRQFEVMAYPSIRYFHENYMKSNSNVGEKMNIADTAERLKNQLIIKLQAEQSMGRLIIAPSFKIESYTSYASALQSVPGDIDYIFLVFENDNSTIGSQIALDVVDYKKVRVKRVYENSELAQVAGVKKIPSVVALENNLQATLLTPKQPTAQNILEEIDRFLKSKNYVFPPKYANMNDISDSSQQRTFVPTSDVAYYNDLEKTLKASLHTEITRHKTLTGEPLQALLDYLDVIKTSFPFRANLGEYIMDLHATLAARNSWTGGEVYDLVKRLETAHEPVYITNLEYVGCKGSEPKYRGYTCGLWTLFHTLTVNAAQKPGSEGPKVLKAMHGYVKNFFGCTECASHFQAMAARNRIFDVKENNKAVLWLWISHNEVNLRLAGDVTEDPEHPKIQFPSATKCPECRLAQGAWNLVAVYDYLQKMYGANNIKDVRRAQVSSASSTFSNLDIGMLSLLYILSFIFIILVIKYFWSKRFYRKRHYKMGMGKV

Catalytic Activity

O2 + 2 R'C(R)SH = H2O2 + R'C(R)S-S(R)CR'

Cofactor

FAD

Feature

chain  Sulfhydryl oxidase

Uniprot

H9ITA1   A0A194QN37   A0A2W1BU08   A0A2A4JQP4   A0A2A4JQR5   A0A2A4JRH9   + More
A0A194PF51   A0A220K8N7   A0A0L7L9F1   A0A2H1W0E0   A0A212F9J4   A0A1W4XTZ0   A0A1Y1LI55   A0A1Y1LCT5   N6TVR9   V5G6I6   U4USZ4   V9PB47   A0A0N1ISZ6   A0A139WK54   A0A195C0V8   A0A154PPC5   D6WHZ3   A0A026VU03   A0A0J7KVA4   A0A195EYN4   F4W5S4   E2AAN0   A0A151X2K2   K7J8R1   A0A158P2R4   E2BAZ4   A0A151I2S1   A0A195DFB6   A0A088A7I5   A0A2A3ED61   A0A0L7QNG1   A0A2J7PGP5   A0A2P8XEJ0   T1PA99   A0A1I8NB55   A0A067REY5   B3MGW1   E0VW74   A0A0L0BP21   A0A1A9VDD5   Q292N7   B4GD11   B4LM00   A0A336K3J4   A0A3B0IZY0   A0A1L8EFD2   A0A1L8EFK0   B4P4K4   A0A0M4EFT4   A0A1B0F9H4   A0A1I8QCB5   B4J5B5   B3NRN7   A0A1A9ZG99   A0A1A9X3I5   A0A034VIE8   A0A0K8V571   Q7JQR3   A0A1B6FCT0   A0A1B0BXH4   A0A1A9YJI3   A0A1B6KLZ5   B4QE06   B4HQ33   A0A1W4UNU0   A0A0C9PXU2   A0A0A1XLR9   B4NLD8   A0A0C9RHA5   A0A0Q9WVL8   A0A139WDJ7   W8C0Z9   A0A023EU40   A0A023EVQ9   A0A023EVD5   A0A182HDX8   A0A182GB20   A0A1S4FVG8   Q16N96   Q9VD61   A0A2S2NV03   B4PKY1   B4QZB9   J9JRQ3   A0A2R7WRG6   E9IPK0   B3P8P9   Q4FDV9   D6WHZ4   A0A2S2R6H8   A0A3Q0JDK6   B3LVJ9   B0UXN0   A0A091QLP6  

EC Number

1.8.3.2

Pubmed

19121390    26354079    28756777    28630352    26227816    22118469    + More
28004739    23537049    18362917    19820115    24508170    21719571    20798317    20075255    21347285    29403074    25315136    24845553    17994087    20566863    26108605    15632085    17550304    25348373    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    25830018    24495485    24945155    26483478    17510324    21282665    15944345    23594743   

EMBL

BABH01007337    KQ461196    KPJ06390.1    KZ149901    PZC78499.1    NWSH01000761    + More
PCG74375.1    PCG74377.1    PCG74376.1    KQ459605    KPI91907.1    MF319731    ASJ26445.1    JTDY01002142    KOB72015.1    ODYU01005567    SOQ46541.1    AGBW02009564    OWR50415.1    GEZM01061174    JAV70707.1    GEZM01061173    JAV70708.1    APGK01050031    APGK01050032    KB741165    ENN73390.1    GALX01002771    JAB65695.1    KB632352    ERL93296.1    KC282396    AGX25153.1    KQ436033    KOX67532.1    KQ971331    KYB28312.1    KQ978379    KYM94477.1    KQ434978    KZC13020.1    EEZ99710.2    KK107921    EZA47207.1    LBMM01002888    KMQ94231.1    KQ981905    KYN33333.1    GL887695    EGI70400.1    GL438137    EFN69480.1    KQ982576    KYQ54667.1    ADTU01007399    ADTU01007400    ADTU01007401    GL446901    EFN87085.1    KQ976518    KYM82197.1    KQ980903    KYN11595.1    KZ288279    PBC29685.1    KQ414851    KOC60182.1    NEVH01025174    PNF15507.1    PYGN01002482    PSN30415.1    KA645070    AFP59699.1    KK852680    KDR18624.1    CH902619    EDV37879.1    DS235817    EEB17630.1    JRES01001578    KNC21807.1    CM000071    EAL24825.1    CH479181    EDW31549.1    CH940648    EDW59920.1    UFQS01000067    UFQT01000067    SSW98991.1    SSX19373.1    OUUW01000001    SPP73895.1    GFDG01001403    JAV17396.1    GFDG01001404    JAV17395.1    CM000158    EDW90643.1    CP012524    ALC41135.1    CCAG010000868    CH916367    EDW01757.1    CH954179    EDV56189.1    GAKP01017045    JAC41907.1    GDHF01018240    GDHF01012411    GDHF01009786    JAI34074.1    JAI39903.1    JAI42528.1    AE013599    BT004854    AAF58400.1    AAO45210.1    GECZ01021764    JAS48005.1    JXJN01022230    GEBQ01027536    JAT12441.1    CM000362    CM002911    EDX06900.1    KMY93452.1    CH480816    EDW47696.1    GBYB01006313    JAG76080.1    GBXI01002759    JAD11533.1    CH964272    EDW84341.1    GBYB01006311    JAG76078.1    KRG00013.1    KQ971358    KYB26006.1    GAMC01011216    JAB95339.1    GAPW01000673    JAC12925.1    GAPW01000431    JAC13167.1    GAPW01000646    JAC12952.1    JXUM01034905    JXUM01034906    KQ561040    KXJ79927.1    JXUM01051977    JXUM01051978    KQ561713    KXJ77746.1    CH477833    EAT35810.1    AE014297    AY070518    AAF55939.1    AAL47989.1    GGMR01008253    MBY20872.1    CM000160    EDW97930.1    CM000364    EDX13855.1    ABLF02026944    KK855357    PTY22158.1    GL764539    EFZ17500.1    CH954182    EDV54213.1    DQ088697    AAZ06444.1    EEZ99709.1    GGMS01016454    MBY85657.1    CH902617    EDV42569.1    CR381643    KK800603    KFQ28460.1   

Proteomes

UP000005204    UP000053240    UP000218220    UP000053268    UP000037510    UP000007151    + More
UP000192223    UP000019118    UP000030742    UP000053105    UP000007266    UP000078542    UP000076502    UP000053097    UP000036403    UP000078541    UP000007755    UP000000311    UP000075809    UP000002358    UP000005205    UP000008237    UP000078540    UP000078492    UP000005203    UP000242457    UP000053825    UP000235965    UP000245037    UP000095301    UP000027135    UP000007801    UP000009046    UP000037069    UP000078200    UP000001819    UP000008744    UP000008792    UP000268350    UP000002282    UP000092553    UP000092444    UP000095300    UP000001070    UP000008711    UP000092445    UP000091820    UP000000803    UP000092460    UP000092443    UP000000304    UP000001292    UP000192221    UP000007798    UP000069940    UP000249989    UP000008820    UP000007819    UP000079169    UP000000437   

PRIDE

H9ITA1    Q7JQR3    Q9VD61   

Pfam

PF00085   Thioredoxin        + More
PF18371   FAD_SOX
PF04777   Evr1_Alr
PF18108   QSOX_Trx1

Interpro

IPR039798   Sulfhydryl_oxidase        + More
IPR036774   ERV/ALR_sulphydryl_oxid_sf       
IPR036249   Thioredoxin-like_sf       
IPR041269   QSOX_Trx1       
IPR017905   ERV/ALR_sulphydryl_oxidase       
IPR017937   Thioredoxin_CS       
IPR013766   Thioredoxin_domain       
IPR040986   QSOX_FAD-bd_dom       

SUPFAM

SSF69000   SSF69000        + More
SSF52833   SSF52833       

Gene 3D

1.20.120.310    

ProteinModelPortal

H9ITA1   A0A194QN37   A0A2W1BU08   A0A2A4JQP4   A0A2A4JQR5   A0A2A4JRH9   + More
A0A194PF51   A0A220K8N7   A0A0L7L9F1   A0A2H1W0E0   A0A212F9J4   A0A1W4XTZ0   A0A1Y1LI55   A0A1Y1LCT5   N6TVR9   V5G6I6   U4USZ4   V9PB47   A0A0N1ISZ6   A0A139WK54   A0A195C0V8   A0A154PPC5   D6WHZ3   A0A026VU03   A0A0J7KVA4   A0A195EYN4   F4W5S4   E2AAN0   A0A151X2K2   K7J8R1   A0A158P2R4   E2BAZ4   A0A151I2S1   A0A195DFB6   A0A088A7I5   A0A2A3ED61   A0A0L7QNG1   A0A2J7PGP5   A0A2P8XEJ0   T1PA99   A0A1I8NB55   A0A067REY5   B3MGW1   E0VW74   A0A0L0BP21   A0A1A9VDD5   Q292N7   B4GD11   B4LM00   A0A336K3J4   A0A3B0IZY0   A0A1L8EFD2   A0A1L8EFK0   B4P4K4   A0A0M4EFT4   A0A1B0F9H4   A0A1I8QCB5   B4J5B5   B3NRN7   A0A1A9ZG99   A0A1A9X3I5   A0A034VIE8   A0A0K8V571   Q7JQR3   A0A1B6FCT0   A0A1B0BXH4   A0A1A9YJI3   A0A1B6KLZ5   B4QE06   B4HQ33   A0A1W4UNU0   A0A0C9PXU2   A0A0A1XLR9   B4NLD8   A0A0C9RHA5   A0A0Q9WVL8   A0A139WDJ7   W8C0Z9   A0A023EU40   A0A023EVQ9   A0A023EVD5   A0A182HDX8   A0A182GB20   A0A1S4FVG8   Q16N96   Q9VD61   A0A2S2NV03   B4PKY1   B4QZB9   J9JRQ3   A0A2R7WRG6   E9IPK0   B3P8P9   Q4FDV9   D6WHZ4   A0A2S2R6H8   A0A3Q0JDK6   B3LVJ9   B0UXN0   A0A091QLP6  

PDB

4P2L     E-value=9.05688e-62,     Score=602

KEGG

101737959    K10758 thiol oxidase [EC:1.8.3.2] | (RefSeq) sulfhydryl oxidase 1-like

GO

GO:0016021   GO:0005623   GO:0016971   GO:0045454   GO:0005615   GO:0003756   GO:0030173   GO:0034975   GO:0016853   GO:0032504   GO:0016491   GO:0016972   GO:0030117   GO:0005198   GO:0030126   GO:0005488   GO:0003677   GO:0003707   GO:0007169   GO:0055114  

PANTHER

PTHR22897  

SignalP

Position:   1 - 19,         Likelihood:  0.952871

 

 

Length:

594

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

32.66204

Exp number, first 60 AAs:

10.45618

Total prob of N-in:

0.49779

POSSIBLE N-term signal

sequence

outside

1  -  554

TMhelix

555  -  577

inside

578  -  594

 

 

Pi

2.325076

Theta

2.36405

Tajima's D

-0.516776

CLR

0.184463

CSRT

0.254937253137343

Interpretation

Uncertain