Gene

KWMTBOMO00435

Pre Gene Modal

BGIBMGA000742

Annotation

PREDICTED:_RING_finger_and_SPRY_domain-containing_protein_1-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr1(+):12766292-12788526      View in EpiBrowser

Full name

RING finger and SPRY domain-containing protein 1      

Location in the cell

Extracellular   Reliability : 1.346 PlasmaMembrane   Reliability : 1.59

CDS

ATGATAGCGATGCTGGGCGATGAAGAGTCACCGGTTCTGCTCGTCAAACTGCACGTGATCGCTGACAAAGAAGAGGGATGGCTGCAAGTCGTCTCGTCAATGGTCAACGTGATACCACTCGACAATCCGCTGGGACCGTCGGCGATCACCATAGTCTTTGATGATTGCCCGCTACCCTCCAGAGACTCTGTCATAAAGCTAACGAAACTGTTCCGGCTGTCGAGGCAACGTGCACTCTCGAACGCCCTCGACGTGAAGATGAAACGCAATATGTGCGTTGTCCTCGGGTGTATTGCCGAGAAACTGGCGGGCCCGAACAGCGTCGCTGTACTCACCGAAGAGACGCTCGACTTTCTCCTTGCATTTCTGGACACCAACTTCGAGCCGTGCATAGTGCTCTTCGCACTAATCGCCCTTGAGAAGTTCGCTCACACCACCGAAAACAAGCTGGTGATAAGAAGCCGCTTCGACAAAGAAGACGTGAATCCACTTCTGAAACTCGAGAAACTTGCCAATAATGAAGATTATGTCTGGAGGCAGGTCGGCTTTTGTGCTCAGTGGGCCCTCGACAACTTGTTTGTAATCGAGAACAGGCCTCTGTCGTACGAGACCGTCGACATGACTCCTATAAACGTGATCCTGAATTCGCATGACGTCAGCGAATACCTGAAGATATCTTGCAACGGCCTAGAGGCGCGCTGCGATTCGTACTCGTTTGAAAGCGTACGCTGCACTTTCCAGGTGGACAATGGCTGTTGGTACTACGAGGTGACGATCGTCACTCCTGGCGTCATGCAGATCGGGTGGGCCACCAAGAACAGCCATTTTCTGAACCATGAGGGCTACGGTATCGGCGACGATTTGTATTCGCTCTCGTACGACGGGTGCAGGAAGTTGATTTGGTACAAGGCCAAGCCCGCTTCGGTCCAAGATCTACCGGAGTGGCAGCCCGGAGACATACTCGGCTGTCTCATCGATCTGAACACGCGCGAGGCAATATTCTCCCTCAACGGGCGCTGTCTTACACCGTGCACCGAAATCTTCGAGACAACCAGGTGCTGCAAACAAGGTTTCTTCGCTGCGGCTAGCTTCATGGCGTTCCAGCAGTGCCGATTCAATTTCGGTCATTTGCCGTTTTCGTTTCCTCCAACTGACAGGCCCTTCATGGCCTTCAACGATTACGCGCGTCTCACCGACGAAGAGAAAAAGGTGCTACCTCGCCGCTACTACCTGGAGAAGGTGAGGAATGCTAGCATCCCCGAAAACGCCTGCACTCTTTGCTACGATGCCGTCGCGGACTGCACCTTGGAGCCATGCTTCCACAAGGGATTCTGCTCGAAATGCGCTGCTCAGCTCCGCGAGTGCCCGTTATGCCGCGCTCCGATACTGAACGTGAAGCGCGACATATGA

Protein

MIAMLGDEESPVLLVKLHVIADKEEGWLQVVSSMVNVIPLDNPLGPSAITIVFDDCPLPSRDSVIKLTKLFRLSRQRALSNALDVKMKRNMCVVLGCIAEKLAGPNSVAVLTEETLDFLLAFLDTNFEPCIVLFALIALEKFAHTTENKLVIRSRFDKEDVNPLLKLEKLANNEDYVWRQVGFCAQWALDNLFVIENRPLSYETVDMTPINVILNSHDVSEYLKISCNGLEARCDSYSFESVRCTFQVDNGCWYYEVTIVTPGVMQIGWATKNSHFLNHEGYGIGDDLYSLSYDGCRKLIWYKAKPASVQDLPEWQPGDILGCLIDLNTREAIFSLNGRCLTPCTEIFETTRCCKQGFFAAASFMAFQQCRFNFGHLPFSFPPTDRPFMAFNDYARLTDEEKKVLPRRYYLEKVRNASIPENACTLCYDAVADCTLEPCFHKGFCSKCAAQLRECPLCRAPILNVKRDI

Keywords

Alternative splicing   Complete proteome   Disease mutation   Dwarfism   Glycoprotein   Mental retardation   Metal-binding   Phosphoprotein   Reference proteome   Secreted   Signal   Zinc   Zinc-finger  

Feature

chain  RING finger and SPRY domain-containing protein 1
splice variant  In isoform 2.
sequence variant  In SEMDFA; dbSNP:rs864309652.

Uniprot

H9IU12   A0A212F9K9   A0A2A4JLR4   A0A2H1V7T4   A0A195D8I4   A0A087ZTN2   + More
E2A5D9   F4WU09   A0A151WWB8   A0A158P114   E2BTH6   A0A195DKG7   A0A026VU71   E9IE86   A0A2J7QJA0   A0A151JUR1   A0A0C9PSP3   A0A0L7QXQ5   A0A310S5F5   A0A232F4I1   A0A0M9A0T5   A0A154P927   A0A2W1BXX5   A0A1Y1M940   A0A2A3EHF8   K7IW25   A0A224Z6A8   A0A131YHF9   A0A131X8M0   L7M7R1   A0A1W4WNC8   E0W1N9   T1IHI8   A0A0P4W5Y0   A0A139WM94   A0A084W854   V5HK78   A0A1B6C6Q6   A0A2R5LBY4   A0A0P4XG14   A0A0P5BBS5   A0A0P5KAI0   A0A1Q3F9D4   A0A293LCM5   A0A182TSS6   A0A1Q3F995   A0A182W705   A0A182JGC5   E9HG27   A0A182R105   A0A1Q3F9D7   A0A182NUG3   A0A1S4GXE5   A0A182HUL7   A0A182L1D3   A0A182WU01   A0A182VHE8   Q17FP0   A0A182JPP5   B0WCT8   A0A182PPL0   W5J8V1   A0A182RCS6   A0A069DVB3   A0A182YQX9   A0A023F3S7   A0A0V0G6F2   A0A1B6I9K8   A0A1B6LFK8   A0A226DPH5   A0A182MGX3   A0A336K6M9   A0A182SCG8   A0A146LYJ7   N6U7R3   U4U011   A0A0P5S2K0   H3B0T0   A0A1D2MGZ7   A0A091R5P2   A0A2Y9STG5   A0A383YXL4   A0A2U3V077   A0A340Y961   A0A0F7YZC5   V8NUH3   A0A2Y9LPD4   A0A094L069   A0A2K5MCV3   A0A2R8ZFC6   H2QB64   A0A024R6U0   Q96DX4   A0A2J8VZ28   Q5R881   Q95LP3   G7Q173   G7NPT9   H0VUL8   Q28E18  

Pubmed

19121390    22118469    20798317    21719571    21347285    24508170    + More
30249741    21282665    28648823    28756777    28004739    20075255    28797301    26830274    28049606    25576852    20566863    18362917    19820115    24438588    25765539    21292972    12364791    20966253    17510324    20920257    23761445    26334808    25244985    25474469    26823975    23537049    9215903    27289101    24297900    22722832    16136131    11181995    11853319    12975309    14702039    15489334    17974005    24275569    26365341    12498619    22002653    25319552    21993624   

EMBL

BABH01007321    AGBW02009564    OWR50417.1    NWSH01001050    PCG72921.1    ODYU01000932    + More
SOQ36442.1    KQ976749    KYN08744.1    GL436921    EFN71361.1    GL888345    EGI62366.1    KQ982691    KYQ52183.1    ADTU01005953    GL450410    EFN81004.1    KQ980765    KYN13332.1    KK107921    QOIP01000001    EZA47190.1    RLU27106.1    GL762567    EFZ21114.1    NEVH01013559    PNF28642.1    KQ981732    KYN36594.1    GBYB01004358    JAG74125.1    KQ414699    KOC63393.1    KQ770168    OAD52697.1    NNAY01001039    OXU25388.1    KQ435797    KOX73499.1    KQ434846    KZC08409.1    KZ149901    PZC78505.1    GEZM01037071    JAV82214.1    KZ288254    PBC30904.1    GFPF01011595    MAA22741.1    GEDV01010190    JAP78367.1    GEFH01004727    JAP63854.1    GACK01004974    JAA60060.1    DS235873    EEB19621.1    JH429910    GDRN01080938    JAI62108.1    KQ971318    KYB28945.1    ATLV01021363    ATLV01021364    KE525317    KFB46398.1    GANP01010570    JAB73898.1    GEDC01028214    JAS09084.1    GGLE01002839    MBY06965.1    GDIP01243206    JAI80195.1    GDIP01187430    JAJ35972.1    GDIQ01188106    GDIP01061198    LRGB01003375    JAK63619.1    JAM42517.1    KZS03011.1    GFDL01010916    JAV24129.1    GFWV01000851    MAA25581.1    GFDL01010900    JAV24145.1    GL732638    EFX69331.1    AXCN02000761    GFDL01010908    JAV24137.1    AAAB01008964    APCN01002465    CH477269    EAT45384.2    DS231890    EDS43814.1    ADMH02001944    ETN60386.1    GBGD01001247    JAC87642.1    GBBI01003148    JAC15564.1    GECL01002504    JAP03620.1    GECU01024108    JAS83598.1    GEBQ01017504    GEBQ01007933    JAT22473.1    JAT32044.1    LNIX01000014    OXA46928.1    AXCM01010210    UFQS01000152    UFQT01000152    SSX00554.1    SSX20934.1    GDHC01005951    JAQ12678.1    APGK01039256    KB740969    ENN76686.1    KB631730    ERL85638.1    GDIQ01093194    JAL58532.1    AFYH01081251    AFYH01081252    AFYH01081253    AFYH01081254    AFYH01081255    AFYH01081256    LJIJ01001280    ODM92278.1    KK809558    KFQ34557.1    GBEW01000820    JAI09545.1    AZIM01001801    ETE65720.1    KL348830    KFZ57554.1    AJFE02083854    AJFE02083855    AJFE02083856    AJFE02083857    AJFE02083858    AJFE02083859    AJFE02083860    AACZ04057487    GABC01010674    GABF01009998    GABD01010852    GABE01011029    GABE01011028    NBAG03000242    JAA00664.1    JAA12147.1    JAA22248.1    JAA33710.1    PNI63784.1    PNI63785.1    CH471092    EAW82911.1    AB075852    AY358548    AK172845    BC013173    AL834402    NDHI03003406    PNJ62756.1    PNJ62758.1    CR859873    AB072745    AQIA01043010    AQIA01043011    AQIA01043012    AQIA01043013    AQIA01043014    AQIA01043015    CM001295    EHH60411.1    JU321980    JU473337    JV044553    CM001272    AFE65736.1    AFH30141.1    AFI34624.1    EHH31691.1    AAKN02026944    BC123024    CR848493    AAI23025.1    CAJ81703.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000078542    UP000005203    UP000000311    + More
UP000007755    UP000075809    UP000005205    UP000008237    UP000078492    UP000053097    UP000279307    UP000235965    UP000078541    UP000053825    UP000215335    UP000053105    UP000076502    UP000242457    UP000002358    UP000192223    UP000009046    UP000007266    UP000030765    UP000076858    UP000075902    UP000075920    UP000075880    UP000000305    UP000075886    UP000075884    UP000075840    UP000075882    UP000076407    UP000075903    UP000008820    UP000075881    UP000002320    UP000075885    UP000000673    UP000075900    UP000076408    UP000198287    UP000075883    UP000075901    UP000019118    UP000030742    UP000008672    UP000094527    UP000248484    UP000261681    UP000245320    UP000265300    UP000248483    UP000233060    UP000240080    UP000002277    UP000005640    UP000001595    UP000233100    UP000009130    UP000005447   

PRIDE

H9IU12    Q96DX4    Q5R881    Q95LP3   

Pfam

PF00622   SPRY

Interpro

IPR003877   SPRY_dom        + More
IPR001870   B30.2/SPRY       
IPR013320   ConA-like_dom_sf       
IPR001841   Znf_RING       
IPR035774   SPRY_RSPRY1       
IPR013083   Znf_RING/FYVE/PHD       
IPR016024   ARM-type_fold       

SUPFAM

SSF49899   SSF49899        + More
SSF48371   SSF48371       

Gene 3D

3.30.40.10    

CDD

cd12883  SPRY_RING

ProteinModelPortal

H9IU12   A0A212F9K9   A0A2A4JLR4   A0A2H1V7T4   A0A195D8I4   A0A087ZTN2   + More
E2A5D9   F4WU09   A0A151WWB8   A0A158P114   E2BTH6   A0A195DKG7   A0A026VU71   E9IE86   A0A2J7QJA0   A0A151JUR1   A0A0C9PSP3   A0A0L7QXQ5   A0A310S5F5   A0A232F4I1   A0A0M9A0T5   A0A154P927   A0A2W1BXX5   A0A1Y1M940   A0A2A3EHF8   K7IW25   A0A224Z6A8   A0A131YHF9   A0A131X8M0   L7M7R1   A0A1W4WNC8   E0W1N9   T1IHI8   A0A0P4W5Y0   A0A139WM94   A0A084W854   V5HK78   A0A1B6C6Q6   A0A2R5LBY4   A0A0P4XG14   A0A0P5BBS5   A0A0P5KAI0   A0A1Q3F9D4   A0A293LCM5   A0A182TSS6   A0A1Q3F995   A0A182W705   A0A182JGC5   E9HG27   A0A182R105   A0A1Q3F9D7   A0A182NUG3   A0A1S4GXE5   A0A182HUL7   A0A182L1D3   A0A182WU01   A0A182VHE8   Q17FP0   A0A182JPP5   B0WCT8   A0A182PPL0   W5J8V1   A0A182RCS6   A0A069DVB3   A0A182YQX9   A0A023F3S7   A0A0V0G6F2   A0A1B6I9K8   A0A1B6LFK8   A0A226DPH5   A0A182MGX3   A0A336K6M9   A0A182SCG8   A0A146LYJ7   N6U7R3   U4U011   A0A0P5S2K0   H3B0T0   A0A1D2MGZ7   A0A091R5P2   A0A2Y9STG5   A0A383YXL4   A0A2U3V077   A0A340Y961   A0A0F7YZC5   V8NUH3   A0A2Y9LPD4   A0A094L069   A0A2K5MCV3   A0A2R8ZFC6   H2QB64   A0A024R6U0   Q96DX4   A0A2J8VZ28   Q5R881   Q95LP3   G7Q173   G7NPT9   H0VUL8   Q28E18  

PDB

5VSN     E-value=1.79559e-10,     Score=159

KEGG

101737506    K23332 RING finger and SPRY domain-containing protein 1 | (RefSeq) RING finger and SPRY domain-conta

GO

GO:0046872   GO:0005576   GO:0005515   GO:0008270   GO:0030117   GO:0005198   GO:0030126   GO:0005488   GO:0003677   GO:0003707   GO:0007169   GO:0016021  

Subcellular location

Secreted  

Length:

469

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.06613

Exp number, first 60 AAs:

0.00046

Total prob of N-in:

0.00326

outside

1  -  469

 

 

Pi

27.133476

Theta

21.613301

Tajima's D

0.356133

CLR

0.077477

CSRT

0.474876256187191

Interpretation

Uncertain