Gene

KWMTBOMO00425

Pre Gene Modal

BGIBMGA000488

Annotation

PREDICTED:_uncharacterized_protein_LOC106719909_[Papilio_machaon]

Location

Bomo_Chr1(-):12433749-12467587      View in EpiBrowser

Full name

Protein grindelwald      

Location in the cell

Nuclear   Reliability : 2.561

CDS

ATGTCGGGATTCGTGTGCGTCCTGATTCTCGCCGGCGTCGCCTCCGCTCAAATCACCCTGGACGGCATCAGATGCGGTCAGCTGATATGTCAGCTAGACGAATACTGCTCCCCGGAGACCAACCGATGCGCTCCGTGCAATGTTGTCTGCAATAAAACACACCATAACTACGATAGCGGCCTTTGCGTTAAGGAATGCCAAGGTTATCTATTGGATTTGAGGTACATGCGACGTTCGGAGACGGCCCCGCCACCCAACGATTTGGGAAGCATACACCGTGAAGCTCAAACTGCTCTGATCGTCAGCGGTGTGGCTCTGGCAGTACTGGTCCTAGTTCTCATCATAGTATGCAGAGGAAGAGTCTCTTGGAGATATTTAAAGCAAAAGTTCCAGCCAGCCAAGAACCGCGTGAAGCAGTACCCTAATGACTTGACGCATCACAACCCTCATGCCGAAGCGCCGAAACCGAAACCCGAACTCAAGCTCGAAATACGAAACCCGGATCCCCTAAGACGAACGAACCAACCTCTCAACGTGAAGGACTTAGAGACCAGAACCTCACAGTCGGATAAAAGTCAAGGCGCAACCACGCCAAAGACGATAAGCACCGCTCTTAGTAACAGGCATCCGGCTGAAGATACGACCTTAGATTTCTCTTATGATAATATGGGGATGAACGTGACTCCCCCCGGACAACCGGCTGCCAGTCACAAATTCTAA

Protein

MSGFVCVLILAGVASAQITLDGIRCGQLICQLDEYCSPETNRCAPCNVVCNKTHHNYDSGLCVKECQGYLLDLRYMRRSETAPPPNDLGSIHREAQTALIVSGVALAVLVLVLIIVCRGRVSWRYLKQKFQPAKNRVKQYPNDLTHHNPHAEAPKPKPELKLEIRNPDPLRRTNQPLNVKDLETRTSQSDKSQGATTPKTISTALSNRHPAEDTTLDFSYDNMGMNVTPPGQPAASHKF

Description

Acts as a receptor for egr. Plays a role in activation of JNK signaling and is required for egr-induced apoptosis. May also play an egr-independent role in cell proliferation.

Subunit

Interacts with egr, Traf6/TRAF2 and veli (via PDZ domain).

Miscellaneous

The name 'grindelwald' comes from the village at the foot of the Eiger mountain in Switzerland after which the egr gene is named.

Keywords

Cell membrane   Complete proteome   Glycoprotein   Membrane   Receptor   Reference proteome   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Protein grindelwald

Uniprot

H9ITA8   A0A2H1WL56   A0A1E1W924   A0A194QN23   A0A212F9Q4   A0A194PGU2   + More
A0A0L7L2F5   A0A1Y1LAD1   A0A1L8D9U4   A0A026X441   A0A0K8TP94   A0A139WI31   A0A158NS59   A0A195DE91   E9IR18   A0A195BCA1   A0A195FW85   N6UAB3   A0A088ARR9   E2A7P7   A0A1J1I659   F4WJQ3   A0A195BYX2   A0A151WH32   E2BD55   A0A1W4V9A8   A0A1W4WBK7   A0A1W4WBZ8   A0A1B6KZE1   A0A067QPA0   A0A1B6CQL4   A0A182NU10   A0A1B6EVB2   A0A182XFW7   A0A182VMS6   A0A2M3Z7J0   A0A2M3Z772   B4P9U6   A0A182UCP6   A0A182QBV2   A0A182L0H7   Q9VJ83   A0A0A9X5S2   A0A0J9R3Z9   A0A1S4GY44   A0A1W4VLD0   B4LTB8   A0A1W4WC23   B3NMB1   A0A182PLS7   A0A1W4VZX9   A0A1A9W0L6   A0A0Q9WBW7   A0A2M4DPE0   A0A182F3H1   A0A3B0K1Y2   A0A1W7R593   A0A2M4AB19   A0A2M4BZ85   A0A2M4BZB0   B4I5H2   A0A2M4AAL4   W5J948   B3MM20   A0A3B0JFL6   A0A2M4DPC5   A0A182K0V5   Q29MP9   Q17K49   A0A2S2NS13   W8B179   W8BZW9   A0A0P8Y325   A0A182J4K1   B4JDL8   A0A182RDS8   A0A182MTC3   A0A0R3NY52   A0A2R7VRS3   A0A0A1X6U9   A0A182YDT0   A0A1I8PEP6   A0A0P4VJ43   A0A0L0CCM1  

Pubmed

19121390    26354079    22118469    26227816    28004739    24508170    + More
30249741    26369729    18362917    19820115    21347285    21282665    23537049    20798317    21719571    24845553    17994087    17550304    20966253    10731132    12537572    25874673    25401762    26823975    22936249    12364791    20920257    23761445    15632085    17510324    24495485    25830018    25244985    27129103    26108605   

EMBL

BABH01007283    BABH01007284    ODYU01009406    SOQ53811.1    GDQN01007581    JAT83473.1    + More
KQ461196    KPJ06375.1    AGBW02009564    OWR50467.1    KQ459605    KPI91924.1    JTDY01003461    KOB69521.1    GEZM01061259    GEZM01061256    JAV70599.1    GFDF01010994    JAV03090.1    KK107031    QOIP01000008    EZA62129.1    RLU19284.1    GDAI01001396    JAI16207.1    KQ971342    KYB27633.1    ADTU01024524    KQ980989    KYN10744.1    GL765043    EFZ16966.1    KQ976528    KYM81829.1    KQ981208    KYN44686.1    APGK01032707    KB740848    ENN78665.1    GL437382    EFN70515.1    CVRI01000038    CRK94422.1    GL888186    EGI65545.1    KQ978457    KYM93849.1    KQ983136    KYQ47115.1    GL447569    EFN86363.1    GEBQ01031309    GEBQ01028440    GEBQ01023154    GEBQ01017119    JAT08668.1    JAT11537.1    JAT16823.1    JAT22858.1    KK853097    KDR11445.1    GEDC01021630    GEDC01007028    JAS15668.1    JAS30270.1    GECZ01030817    GECZ01027833    GECZ01003095    JAS38952.1    JAS41936.1    JAS66674.1    GGFM01003748    MBW24499.1    GGFM01003616    MBW24367.1    CM000158    EDW90287.2    AXCN02000809    AE014134    AY084146    AAL89884.1    GBHO01028260    GBRD01008136    GBRD01008134    GDHC01012356    GDHC01009407    GDHC01000299    JAG15344.1    JAG57685.1    JAQ06273.1    JAQ09222.1    JAQ18330.1    CM002910    KMY90818.1    AAAB01008964    CH940649    EDW64960.1    CH954179    EDV54782.2    KRF81954.1    GGFL01015246    MBW79424.1    OUUW01000004    SPP79011.1    GEHC01001298    JAV46347.1    GGFK01004629    MBW37950.1    GGFJ01009212    MBW58353.1    GGFJ01009211    MBW58352.1    CH480822    EDW55628.1    GGFK01004498    MBW37819.1    ADMH02001920    ETN60506.1    CH902620    EDV30835.1    SPP79012.1    GGFL01015245    MBW79423.1    CH379060    EAL33644.3    CH477228    EAT47044.1    GGMR01006927    MBY19546.1    GAMC01011710    GAMC01011708    JAB94845.1    GAMC01011711    GAMC01011709    JAB94844.1    KPU73075.1    CH916368    EDW03388.1    AXCM01001334    KRT04085.1    KK854020    PTY09531.1    GBXI01017335    GBXI01007475    GBXI01003425    JAC96956.1    JAD06817.1    JAD10867.1    GDKW01002462    JAI54133.1    JRES01000592    KNC30000.1   

Proteomes

UP000005204    UP000053240    UP000007151    UP000053268    UP000037510    UP000053097    + More
UP000279307    UP000007266    UP000005205    UP000078492    UP000078540    UP000078541    UP000019118    UP000005203    UP000000311    UP000183832    UP000007755    UP000078542    UP000075809    UP000008237    UP000192221    UP000027135    UP000075884    UP000076407    UP000075903    UP000002282    UP000075902    UP000075886    UP000075882    UP000000803    UP000008792    UP000008711    UP000075885    UP000091820    UP000069272    UP000268350    UP000001292    UP000000673    UP000007801    UP000075881    UP000001819    UP000008820    UP000075880    UP000001070    UP000075900    UP000075883    UP000076408    UP000095300    UP000037069   

PRIDE

H9ITA8    Q9VJ83   

ProteinModelPortal

H9ITA8   A0A2H1WL56   A0A1E1W924   A0A194QN23   A0A212F9Q4   A0A194PGU2   + More
A0A0L7L2F5   A0A1Y1LAD1   A0A1L8D9U4   A0A026X441   A0A0K8TP94   A0A139WI31   A0A158NS59   A0A195DE91   E9IR18   A0A195BCA1   A0A195FW85   N6UAB3   A0A088ARR9   E2A7P7   A0A1J1I659   F4WJQ3   A0A195BYX2   A0A151WH32   E2BD55   A0A1W4V9A8   A0A1W4WBK7   A0A1W4WBZ8   A0A1B6KZE1   A0A067QPA0   A0A1B6CQL4   A0A182NU10   A0A1B6EVB2   A0A182XFW7   A0A182VMS6   A0A2M3Z7J0   A0A2M3Z772   B4P9U6   A0A182UCP6   A0A182QBV2   A0A182L0H7   Q9VJ83   A0A0A9X5S2   A0A0J9R3Z9   A0A1S4GY44   A0A1W4VLD0   B4LTB8   A0A1W4WC23   B3NMB1   A0A182PLS7   A0A1W4VZX9   A0A1A9W0L6   A0A0Q9WBW7   A0A2M4DPE0   A0A182F3H1   A0A3B0K1Y2   A0A1W7R593   A0A2M4AB19   A0A2M4BZ85   A0A2M4BZB0   B4I5H2   A0A2M4AAL4   W5J948   B3MM20   A0A3B0JFL6   A0A2M4DPC5   A0A182K0V5   Q29MP9   Q17K49   A0A2S2NS13   W8B179   W8BZW9   A0A0P8Y325   A0A182J4K1   B4JDL8   A0A182RDS8   A0A182MTC3   A0A0R3NY52   A0A2R7VRS3   A0A0A1X6U9   A0A182YDT0   A0A1I8PEP6   A0A0P4VJ43   A0A0L0CCM1  

KEGG

101737163    no KO assigned | (RefSeq) uncharacterized LOC101737163

GO

GO:0016021   GO:0005031   GO:0046330   GO:2001235   GO:0005886   GO:0016324   GO:0033209   GO:0016853  

Subcellular location

Apical cell membrane  

SignalP

Position:   1 - 16,         Likelihood:  0.999002

 

 

Length:

239

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

25.78395

Exp number, first 60 AAs:

3.73489

Total prob of N-in:

0.20617

outside

1  -  94

TMhelix

95  -  117

inside

118  -  239

 

 

Pi

17.535452

Theta

21.052772

Tajima's D

-0.877304

CLR

0.052352

CSRT

0.15959202039898

Interpretation

Uncertain