Gene

KWMTBOMO00417

Pre Gene Modal

BGIBMGA000489

Annotation

PREDICTED:_V-type_proton_ATPase_116_kDa_subunit_a_isoform_1-like_[Bombyx_mori]

Location

Bomo_Chr1(-):12296459-12306747      View in EpiBrowser

Full name

V-type proton ATPase subunit a      

Location in the cell

PlasmaMembrane   Reliability : 4.847

CDS

ATGGAAATTAGGAAAGTGGCATTCTTAGCCGTCTGCCAGGGCGAAGAGCTTAGCACGAGAATGGAAAAAATATTTAGTGGCTTCCGGGTGAACTCATACCCGTGCCCGGAATCTGCTAAGGAGCGACTAGAAATGATAAGTCAGCTAGAAACGAGGATGAGCGATTTAGAAGAGATTTTGAGTAAATCAAAGTACATTCGCTGCAAAACCTTACGGACTGTCGGCAAGCAATGGCAGAACGGAATTGTACAAGTGAAAAAAGCCAAGGCGATTTATCATACCATGAACCTTTTCTCCTTGGACATTACAAAGAAATGTCTAATTGGCCAATGCTGGATACCGGAACGCGATCTCATGAGAGTTCAAGACATTTTAGTGGAATGCTCGGAAACGATCGGTACAAATGTGCCCTCATTTATATCTAAAACTACGTTTTCAATGTCGCCGCCCACGTTCAATCGTACGAACAAATACACGCACGGCTTTCAAGTTCTGATCAATGCTTACGGCGATTCTATGTACAGGGAACTGAATCCAGCTCTTTATACAATAATATCTTTCCCGTTTTTGTTTGCTTTGATGTTCGGTGATATGGGACACGCTTTAATATTATTGTCGTTTTCTACTTGGATGGTTAAAAACGAGGAAAAATTCATAGCCATGAAAAGTAGAAATGAGATTTGGAACATTATATTTGGAGGTCGCTATATCATTTTATTGATGGGCATGTTCAGTTTTTTTTCCGGTGTTGTGTACAACGATTGTTTCGGCAGGTCGATAGTACCAATGCCGTCTTATTGGGTGAATACCTTCTCTTCAGAAGCCCTAGCTAAACAAAGTGTCCTCAATTTAGACCCGAAAGGGAAAACGAGAAATCTTTATTTATTGGGCGTTGACCCTGTCTGGGGCGTCGCAAAGAATAACATAATATATGAAAATTCTATTAAAATGAAGTTTTCTATAATTGTCGGAGTCCTTCATATGATATTTGGTTTAAATTTGAGCGTTGTAAACCATTGGTACCTGAATCGCCGATACTTAATAGTTTTTCAATTTATACCTGAAATTGTATTTTTAACCTGCATTTTCATGTGGCTGGTACTGCTGATGTTTTTCAAATGGTTCATGTATAGTGGTAAAATAAGTAAGTACTGTTGA

Protein

MEIRKVAFLAVCQGEELSTRMEKIFSGFRVNSYPCPESAKERLEMISQLETRMSDLEEILSKSKYIRCKTLRTVGKQWQNGIVQVKKAKAIYHTMNLFSLDITKKCLIGQCWIPERDLMRVQDILVECSETIGTNVPSFISKTTFSMSPPTFNRTNKYTHGFQVLINAYGDSMYRELNPALYTIISFPFLFALMFGDMGHALILLSFSTWMVKNEEKFIAMKSRNEIWNIIFGGRYIILLMGMFSFFSGVVYNDCFGRSIVPMPSYWVNTFSSEALAKQSVLNLDPKGKTRNLYLLGVDPVWGVAKNNIIYENSIKMKFSIIVGVLHMIFGLNLSVVNHWYLNRRYLIVFQFIPEIVFLTCIFMWLVLLMFFKWFMYSGKISKYC

Description

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.

Similarity

Belongs to the V-ATPase 116 kDa subunit family.

Uniprot

A0A2H1VTT6   A0A2A4JNX8   A0A2H1WFR4   A0A194PGT7   H9IYU7   A0A2M4A1N0   + More
A0A2S2R544   A0A194QLY9   A0A194QD04   A0A2M4A171   A0A2M4A1G6   A0A1B6D6J7   B4M3Z5   A0A0M5J4P9   A0A2S2PBT8   A0A023EW58   B4K928   B4JF18   B3LW99   A0A182M9P0   A0A182YAM6   B0W8G6   W5JMD3   A0A182QWU8   A0A2M3YYN2   A0A2M3YYH4   A0A2M4BEH6   B4PLX2   S4PLD6   B4N9D9   A0A2S2NU12   B4QUE6   Q299L9   Q16HE2   B4I290   Q9VE75   U5EY09   A0A1W4U7R6   A0A2S2PWB7   B4G5D7   A0A1Q3FCP1   A0A2R7VQB9   Q7PKS7   A0A182USZ7   A0A182UDQ6   A0A182IX69   A0A182L9N2   A0A2C9GQN9   Q8T5K2   A0A2H8TPX0   A0A3B0KN56   A0A182PGR3   A0A0K8TQR7   A0A1E1WPT2   J9JQN3   A0A1B6GC23   A0A1B6GGF1   A0A194RMC5   A0A1B6FUG7   A0A1B6FW59   A0A1B1UZP4   A0A0K8UV85   A0A0K8V9Z6   A0A034VLS7   A0A1I8NRD1   T1PG42   A0A0P4VSQ7   A0A182F7K3   A0A224X7A5   A0A182VZ95   A0A212ESI2   A0A0V0G756   A0A1B6MKV2   A0A1B6MPW5   A0A182NS68   E9IIE3   A0A182R647   A0A1A9W3I6   A0A1B0D7J1   A0A067RRK3   A0A182WSF2   A0A3Q0J182   A0A182J1T3   A0A069DZK8   A0A139WNM9   A0A2J7QFR3   A0A139WNA2   W8BF11   A0A2J7QFV2   V9I8F9   A0A336KNK4   A0A1B6LTV6   A0A139WN36   A0A1B6KJ67   A0A0A9ZB73   D6WCX7   A0A0A1X2U8   E0VZ05   A0A336M7G7  

Pubmed

26354079    19121390    17994087    18057021    24945155    26483478    + More
25244985    20920257    23761445    17550304    23622113    15632085    17510324    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12364791    14747013    17210077    20966253    12060762    26369729    25348373    25315136    27129103    22118469    21282665    24845553    26334808    18362917    19820115    24495485    25401762    25830018    20566863   

EMBL

ODYU01004399    SOQ44233.1    NWSH01000875    PCG73765.1    ODYU01008382    SOQ51925.1    + More
KQ459605    KPI91919.1    BABH01010757    BABH01010758    BABH01010759    GGFK01001376    MBW34697.1    GGMS01015647    MBY84850.1    KQ461196    KPJ06379.1    KQ459220    KPJ02860.1    GGFK01001212    MBW34533.1    GGFK01001312    MBW34633.1    GEDC01030163    GEDC01027538    GEDC01018456    GEDC01015987    JAS07135.1    JAS09760.1    JAS18842.1    JAS21311.1    CH940652    EDW59356.1    KRF78813.1    CP012526    ALC46094.1    GGMR01014235    MBY26854.1    JXUM01123189    JXUM01123190    JXUM01123191    JXUM01123192    GAPW01000216    JAC13382.1    CH933806    EDW14441.1    KRG01017.1    CH916369    EDV93299.1    CH902617    EDV42677.1    KPU79847.1    AXCM01006747    DS231859    EDS39016.1    ADMH02001150    ETN63909.1    AXCN02000267    GGFM01000600    MBW21351.1    GGFM01000527    MBW21278.1    GGFJ01002077    MBW51218.1    CM000160    EDW95904.1    GAIX01004080    JAA88480.1    CH964232    EDW80572.1    GGMR01007929    MBY20548.1    CM000364    EDX12446.1    CM000070    EAL27684.1    CH478180    EAT33671.1    CH480820    EDW54647.1    AF132183    AE014297    AAD34771.1    AAF55552.2    GANO01000631    JAB59240.1    GGMS01000632    MBY69835.1    CH479179    EDW24803.1    GFDL01009700    JAV25345.1    KK854026    PTY09713.1    AAAB01008987    EAA43151.2    APCN01000888    AJ439060    CAD27758.1    GFXV01004235    MBW16040.1    OUUW01000013    SPP88009.1    GDAI01000904    JAI16699.1    GDQN01008557    GDQN01001991    JAT82497.1    JAT89063.1    ABLF02024323    GECZ01009916    JAS59853.1    GECZ01008283    JAS61486.1    KQ459984    KPJ18978.1    GECZ01015944    JAS53825.1    GECZ01015375    JAS54394.1    KU550964    ANW09710.1    GDHF01029529    GDHF01021876    JAI22785.1    JAI30438.1    GDHF01016550    JAI35764.1    GAKP01016222    JAC42730.1    KA646853    AFP61482.1    GDKW01000421    JAI56174.1    GFTR01008140    JAW08286.1    AGBW02012778    OWR44452.1    GECL01002185    JAP03939.1    GEBQ01024009    GEBQ01003411    JAT15968.1    JAT36566.1    GEBQ01009678    GEBQ01002003    JAT30299.1    JAT37974.1    GL763459    EFZ19682.1    AJVK01026954    KK852470    KDR23260.1    GBGD01000465    JAC88424.1    KQ971311    KYB29411.1    NEVH01014852    PNF27424.1    KYB29412.1    GAMC01006625    JAB99930.1    PNF27423.1    JR036125    AEY56937.1    UFQS01000635    UFQT01000635    SSX05612.1    SSX25971.1    GEBQ01012881    JAT27096.1    KYB29410.1    GEBQ01028484    JAT11493.1    GBHO01021481    GBHO01001930    JAG22123.1    JAG41674.1    EEZ99071.2    GBXI01008638    JAD05654.1    DS235848    EEB18611.1    SSX05611.1    SSX25970.1   

Proteomes

UP000218220    UP000053268    UP000005204    UP000053240    UP000008792    UP000092553    + More
UP000069940    UP000009192    UP000001070    UP000007801    UP000075883    UP000076408    UP000002320    UP000000673    UP000075886    UP000002282    UP000007798    UP000000304    UP000001819    UP000008820    UP000001292    UP000000803    UP000192221    UP000008744    UP000007062    UP000075903    UP000075902    UP000075880    UP000075882    UP000075840    UP000268350    UP000075885    UP000007819    UP000095300    UP000095301    UP000069272    UP000075920    UP000007151    UP000075884    UP000091820    UP000092462    UP000027135    UP000076407    UP000079169    UP000007266    UP000235965    UP000009046   

PRIDE

H9IYU7    Q9VE75   

Pfam

PF01496   V_ATPase_I

Interpro

IPR026028   V-type_ATPase_116kDa_su_euka        + More
IPR002490   V-ATPase_116kDa_su       

ProteinModelPortal

A0A2H1VTT6   A0A2A4JNX8   A0A2H1WFR4   A0A194PGT7   H9IYU7   A0A2M4A1N0   + More
A0A2S2R544   A0A194QLY9   A0A194QD04   A0A2M4A171   A0A2M4A1G6   A0A1B6D6J7   B4M3Z5   A0A0M5J4P9   A0A2S2PBT8   A0A023EW58   B4K928   B4JF18   B3LW99   A0A182M9P0   A0A182YAM6   B0W8G6   W5JMD3   A0A182QWU8   A0A2M3YYN2   A0A2M3YYH4   A0A2M4BEH6   B4PLX2   S4PLD6   B4N9D9   A0A2S2NU12   B4QUE6   Q299L9   Q16HE2   B4I290   Q9VE75   U5EY09   A0A1W4U7R6   A0A2S2PWB7   B4G5D7   A0A1Q3FCP1   A0A2R7VQB9   Q7PKS7   A0A182USZ7   A0A182UDQ6   A0A182IX69   A0A182L9N2   A0A2C9GQN9   Q8T5K2   A0A2H8TPX0   A0A3B0KN56   A0A182PGR3   A0A0K8TQR7   A0A1E1WPT2   J9JQN3   A0A1B6GC23   A0A1B6GGF1   A0A194RMC5   A0A1B6FUG7   A0A1B6FW59   A0A1B1UZP4   A0A0K8UV85   A0A0K8V9Z6   A0A034VLS7   A0A1I8NRD1   T1PG42   A0A0P4VSQ7   A0A182F7K3   A0A224X7A5   A0A182VZ95   A0A212ESI2   A0A0V0G756   A0A1B6MKV2   A0A1B6MPW5   A0A182NS68   E9IIE3   A0A182R647   A0A1A9W3I6   A0A1B0D7J1   A0A067RRK3   A0A182WSF2   A0A3Q0J182   A0A182J1T3   A0A069DZK8   A0A139WNM9   A0A2J7QFR3   A0A139WNA2   W8BF11   A0A2J7QFV2   V9I8F9   A0A336KNK4   A0A1B6LTV6   A0A139WN36   A0A1B6KJ67   A0A0A9ZB73   D6WCX7   A0A0A1X2U8   E0VZ05   A0A336M7G7  

PDB

6O7T     E-value=2.95134e-64,     Score=622

KEGG

101736898    K02154 V-type H+-transporting ATPase subunit a | (RefSeq) V-type proton ATPase 116 kDa subunit a iso

GO

GO:0015078   GO:0016021   GO:0015991   GO:0000220   GO:0033179   GO:0033181   GO:0046961   GO:0051117   GO:0016471   GO:0007035   GO:0005886   GO:0006811   GO:0016787   GO:0016020   GO:0005667   GO:0005737   GO:0003677   GO:0003707   GO:0007169  

PANTHER

PTHR11629  

Length:

385

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

90.86008

Exp number, first 60 AAs:

0

Total prob of N-in:

0.40731

inside

1  -  180

TMhelix

181  -  203

outside

204  -  230

TMhelix

231  -  253

inside

254  -  318

TMhelix

319  -  341

outside

342  -  355

TMhelix

356  -  378

inside

379  -  385

 

 

Pi

19.249853

Theta

19.508986

Tajima's D

-0.55294

CLR

0.039323

CSRT

0.233738313084346

Interpretation

Uncertain