Gene

KWMTBOMO00416

Annotation

PREDICTED:_V-type_proton_ATPase_116_kDa_subunit_a_isoform_1-like_[Bombyx_mori]

Location

Bomo_Chr1(-):12282756-12294437      View in EpiBrowser

Full name

V-type proton ATPase subunit a      

Location in the cell

PlasmaMembrane   Reliability : 4.048

CDS

ATGCACAAATCCACAAATAACTATTTCGATTATCGATTACGATATAATAACAGTGGCAAGCGAGGTGCAAATTGTGCTCCTCAAATTCTGATATTATTCATTGACATGTTCCTATGGACTAAAACGAAACCGGTGGGCGCGAACTGCGACGCGTACATGTTCAACAAACAAGAATTAGTTCAGAAGATACTGATGATTATAGCCATATCGTGTATACCTTTACTTTTATTGGGAACACCTGTGTATTTGTACTGTACTAACAAAAAGAAAACACAAAAGCCTGATGTCAAAGTGAGTGATTTCAGAAGATATCAGAGAAGAGACTCTGATGAAGAAAGGAAGGAACCTAAGAAAACCAGCGAAAAAGAGCACGACAGTTCTTCATTTGGGGATTTAATGATTCATCAAGCAGTACACACAATAGAGTTTGTCCTCAGTACAATATCACATACAGCTTCGTATTTGAGACTATGGGCATTATCTTTGGCGCATGTTGAATTATCAGAAATGTTATGGAATATGGTACTATCGAAACTGGCCTTACGGGACTACTCGATGTTCGGTGCCATCAAGGTATTCATCATATTCAGCGTTTGGGTCATGTTCACTATCTCCATTTTGGTGGTAATGGAGGGGCTATCTGCTTTCCTTCACACTTTAAGATTGCATTGGGTCGAGTTTATGAGCAAATTCTACATTGGAGGTGGATATCCGTTCCGACCTTTTAGTTTTGAAAACATATTGACAGCTGAAACGGAAAAATCAAAAGGAGAAAAGGGGGGGGCTACACATGACAACAGCAACAATGTTTAA

Protein

MHKSTNNYFDYRLRYNNSGKRGANCAPQILILFIDMFLWTKTKPVGANCDAYMFNKQELVQKILMIIAISCIPLLLLGTPVYLYCTNKKKTQKPDVKVSDFRRYQRRDSDEERKEPKKTSEKEHDSSSFGDLMIHQAVHTIEFVLSTISHTASYLRLWALSLAHVELSEMLWNMVLSKLALRDYSMFGAIKVFIIFSVWVMFTISILVVMEGLSAFLHTLRLHWVEFMSKFYIGGGYPFRPFSFENILTAETEKSKGEKGGATHDNSNNV

Description

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.

Similarity

Belongs to the V-ATPase 116 kDa subunit family.

Uniprot

A0A212F9Q1   A0A2A4JNX8   A0A194QLY9   A0A212ESI2   A0A2H1VTT6   S4PLD6   + More
A0A194PGT7   A0A2J7RKU0   A0A1Y1JVN1   A0A1Y1JSJ5   A0A194QD04   H9IYU7   A0A1E1WPT2   A0A1B0D7J1   A0A194RMC5   U4U2F9   A0A1L8DEX4   N6TTR3   A0A1L8DEM8   N6TW70   A0A1B1UZP4   A0A1A9ZXN1   I4DKT0   B4JF18   A0A1A9WZJ6   A0A1A9VER2   A0A2J7RKU2   A0A1B0B2T6   A0A2C9GQN9   A0A0T6B4L8   U4UTM9   A0A2S2NU12   A0A182L9N2   A0A0K8TQR7   A0A1B0BJB3   A0A182PGR3   E9JC15   A0A182QWU8   Q7PKS7   A0A182USZ7   A0A182UDQ6   A0A2H8TPX0   W8BF11   B4QUE6   B4K928   T1PG42   A0A1L8EDJ5   A0A023EW58   A0A0J7KVX7   E2ALT3   B4M3Z5   A0A182YAM6   B4N9D9   A0A1L8EDB7   A0A1I8NPJ9   A0A1I8NPJ3   A0A1I8NPI8   A0A1I8NPI2   A0A2M3YYH4   A0A2M3YYN2   B4QUE7   B4N9D8   A0A2M4BEH6   A0A1I8PV36   K7J2E3   B3LW99   B4I290   A0A1Y0AWR1   A0A1B6MKV2   A0A0M5J4P9   Q9VE75   A0A1B6MPW5   A0A1I8N3G5   A0A1I8N3H3   A0A1I8N3G6   A0A182WSF2   A0A1I8N3I7   A0A195CD36   A0A1I8NPI7   A0A1I8NRD1   W5JMD3   A0A2M4A1N0   A0A1I8NPJ5   A0A1I8NPI9   A0A1I8NPJ1   Q16HE2   B4PLX2   A0A182M9P0   A0A310S7A1   A0A1B0F9Q1   A0A1I8N3H0   A0A1I8N3I1   A0A1I8N3G3   Q8T5K2   A0A0L0C6R8   J9JQN3   A0A1I8N3I0   B4PLX1   A0A0A1X2U8   A0A1Q3FCP1  

Pubmed

22118469    26354079    23622113    28004739    19121390    23537049    + More
22651552    17994087    20966253    26369729    21282665    12364791    14747013    17210077    24495485    18057021    25315136    24945155    26483478    20798317    25244985    20075255    28341416    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20920257    23761445    17510324    17550304    12060762    26108605    25830018   

EMBL

AGBW02009564    OWR50461.1    NWSH01000875    PCG73765.1    KQ461196    KPJ06379.1    + More
AGBW02012778    OWR44452.1    ODYU01004399    SOQ44233.1    GAIX01004080    JAA88480.1    KQ459605    KPI91919.1    NEVH01002707    PNF41458.1    GEZM01101880    GEZM01101878    JAV52238.1    GEZM01101879    JAV52239.1    KQ459220    KPJ02860.1    BABH01010757    BABH01010758    BABH01010759    GDQN01008557    GDQN01001991    JAT82497.1    JAT89063.1    AJVK01026954    KQ459984    KPJ18978.1    KB631625    ERL84786.1    GFDF01009184    JAV04900.1    APGK01052546    KB741213    ENN72620.1    GFDF01009183    JAV04901.1    ENN72621.1    KU550964    ANW09710.1    AK401898    BAM18520.1    CH916369    EDV93299.1    PNF41457.1    JXJN01007702    APCN01000888    LJIG01009864    KRT82228.1    KI208410    KI210033    ERL95858.1    ERL96138.1    GGMR01007929    MBY20548.1    GDAI01000904    JAI16699.1    JXJN01015358    GL771642    EFZ09639.1    AXCN02000267    AAAB01008987    EAA43151.2    GFXV01004235    MBW16040.1    GAMC01006625    JAB99930.1    CM000364    EDX12446.1    CH933806    EDW14441.1    KRG01017.1    KA646853    AFP61482.1    GFDG01002067    JAV16732.1    JXUM01123189    JXUM01123190    JXUM01123191    JXUM01123192    GAPW01000216    JAC13382.1    LBMM01002578    KMQ94637.1    GL440629    EFN65603.1    CH940652    EDW59356.1    KRF78813.1    CH964232    EDW80572.1    GFDG01002069    JAV16730.1    GGFM01000527    MBW21278.1    GGFM01000600    MBW21351.1    EDX12447.1    EDW80571.1    GGFJ01002077    MBW51218.1    AAZX01007551    CH902617    EDV42677.1    KPU79847.1    CH480820    EDW54647.1    KY921837    ART29426.1    GEBQ01024009    GEBQ01003411    JAT15968.1    JAT36566.1    CP012526    ALC46094.1    AF132183    AE014297    AAD34771.1    AAF55552.2    GEBQ01009678    GEBQ01002003    JAT30299.1    JAT37974.1    KQ977935    KYM98717.1    ADMH02001150    ETN63909.1    GGFK01001376    MBW34697.1    CH478180    EAT33671.1    CM000160    EDW95904.1    AXCM01006747    KQ780345    OAD51949.1    CCAG010019856    AJ439060    CAD27758.1    JRES01000835    KNC27927.1    ABLF02024323    EDW95903.1    GBXI01008638    JAD05654.1    GFDL01009700    JAV25345.1   

Proteomes

UP000007151    UP000218220    UP000053240    UP000053268    UP000235965    UP000005204    + More
UP000092462    UP000030742    UP000019118    UP000092445    UP000001070    UP000091820    UP000078200    UP000092460    UP000075840    UP000075882    UP000075885    UP000075886    UP000007062    UP000075903    UP000075902    UP000000304    UP000009192    UP000095301    UP000069940    UP000036403    UP000000311    UP000008792    UP000076408    UP000007798    UP000095300    UP000002358    UP000007801    UP000001292    UP000092553    UP000000803    UP000076407    UP000078542    UP000000673    UP000008820    UP000002282    UP000075883    UP000092444    UP000037069    UP000007819   

PRIDE

H9IYU7    Q9VE75   

Pfam

PF01496   V_ATPase_I

Interpro

IPR002490   V-ATPase_116kDa_su        + More
IPR026028   V-type_ATPase_116kDa_su_euka       

ProteinModelPortal

A0A212F9Q1   A0A2A4JNX8   A0A194QLY9   A0A212ESI2   A0A2H1VTT6   S4PLD6   + More
A0A194PGT7   A0A2J7RKU0   A0A1Y1JVN1   A0A1Y1JSJ5   A0A194QD04   H9IYU7   A0A1E1WPT2   A0A1B0D7J1   A0A194RMC5   U4U2F9   A0A1L8DEX4   N6TTR3   A0A1L8DEM8   N6TW70   A0A1B1UZP4   A0A1A9ZXN1   I4DKT0   B4JF18   A0A1A9WZJ6   A0A1A9VER2   A0A2J7RKU2   A0A1B0B2T6   A0A2C9GQN9   A0A0T6B4L8   U4UTM9   A0A2S2NU12   A0A182L9N2   A0A0K8TQR7   A0A1B0BJB3   A0A182PGR3   E9JC15   A0A182QWU8   Q7PKS7   A0A182USZ7   A0A182UDQ6   A0A2H8TPX0   W8BF11   B4QUE6   B4K928   T1PG42   A0A1L8EDJ5   A0A023EW58   A0A0J7KVX7   E2ALT3   B4M3Z5   A0A182YAM6   B4N9D9   A0A1L8EDB7   A0A1I8NPJ9   A0A1I8NPJ3   A0A1I8NPI8   A0A1I8NPI2   A0A2M3YYH4   A0A2M3YYN2   B4QUE7   B4N9D8   A0A2M4BEH6   A0A1I8PV36   K7J2E3   B3LW99   B4I290   A0A1Y0AWR1   A0A1B6MKV2   A0A0M5J4P9   Q9VE75   A0A1B6MPW5   A0A1I8N3G5   A0A1I8N3H3   A0A1I8N3G6   A0A182WSF2   A0A1I8N3I7   A0A195CD36   A0A1I8NPI7   A0A1I8NRD1   W5JMD3   A0A2M4A1N0   A0A1I8NPJ5   A0A1I8NPI9   A0A1I8NPJ1   Q16HE2   B4PLX2   A0A182M9P0   A0A310S7A1   A0A1B0F9Q1   A0A1I8N3H0   A0A1I8N3I1   A0A1I8N3G3   Q8T5K2   A0A0L0C6R8   J9JQN3   A0A1I8N3I0   B4PLX1   A0A0A1X2U8   A0A1Q3FCP1  

PDB

6O7T     E-value=2.13977e-46,     Score=466

KEGG

101736898    K02154 V-type H+-transporting ATPase subunit a | (RefSeq) V-type proton ATPase 116 kDa subunit a iso

GO

GO:0015078   GO:0033179   GO:0016021   GO:0015991   GO:0000220   GO:0033181   GO:0051117   GO:0016471   GO:0046961   GO:0007035   GO:0005886   GO:0016020   GO:0005667   GO:0005737   GO:0003677   GO:0003707   GO:0007169  

PANTHER

PTHR11629  

Length:

270

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

65.17385

Exp number, first 60 AAs:

17.81728

Total prob of N-in:

0.92397

POSSIBLE N-term signal

sequence

inside

1  -  20

TMhelix

21  -  40

outside

41  -  62

TMhelix

63  -  85

inside

86  -  186

TMhelix

187  -  209

outside

210  -  270

 

 

Pi

21.916013

Theta

20.859145

Tajima's D

-0.943183

CLR

0.026662

CSRT

0.152792360381981

Interpretation

Uncertain