Gene

KWMTBOMO00393  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000723

Annotation

PREDICTED:_prostaglandin_E_synthase_2_[Bombyx_mori]

Location

Bomo_Chr1(+):11553669-11558356      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 1.954

CDS

ATGTGGCGATCAACACTAACACTATTAAGAAAAATTGTGGTTCCGTCGCTGAAAGAGAATTTGCAGCAATCCAAAACATTATTTTCCACTAAGTCACGGCCTAGATCGACGGTGAGGTTAACACTCATCAGTGCCGGGATAGGAGTTCTTGTTGGAGCTGGCTATGGAGGTTATACACATTACAAAATAAACGCGAAAAAACGTACACTTCCTCAAGAAAACGAAGAATATGCATTTTTAAAGCAAGCACCCAAGTACACACCGCAGTATTGTGTTATAAATGATTCAGATACTAGTAATCTTAGCTTAGTTCTGTTCCAATACAGAACCTGTCCATTTTGCTGTAAAGTCCGTGCCTATCTTGATGCCCGTGGTATCAGTTATGAGGTAGTTGAAGTTGATGCTGTACTTCGTCAAGCAATCAAGTGGTCTGGTTATAAAAAAGTGCCTATTGTCCTCGCTAAAGTGGATGGAGGGTACCAGCAATTACTTGATAGTACAGCAATAATATCTATCCTTGAAACATATTTATTAGACAAAAAATCTCAATTAACTGAAATCATAAAATTTTATCCTGTATCTCAATTTGTTAATGATGCAGGGAAGAACATAACAGAAATTACCAATAAATATTTCATAATGCATAATTCTCCATTAAGTAATGACAACGAGAAGTCTGCAGAATTAGAAGAACGGAAATGGCGCCAATGGGCTGACACTGTTCTGGTGCACACATTATCACCAAATGTTTATCGGACACCGGGTGAAGCTTTAGAAACATTCAAATGGTTTGAACAAGCGGGGCGCTGGAAAGAATCGTTCCCGGGCTGGGAATGTGCACTCATGGTTTATGTCGGAGCTGCAGCTATGTGGATGATTGCCAAACGACTTAAGAAAAGACACAATATTAGTGATGATGTCCGTCAGTCTCTTTATGATGCAGCAAATGAATGGACTATCGCAGTAAACAAAAAAGGAAAACGATTTTTTGGCGGGGATGCCCCTAATTTAGCAGATATCACTGTGTACGGAGTGTTAAGTAGCATTGAAGGTTGCATGGCATTCAAAGATTTAAGAAACAATACTCAAATCGCGAAGTGGTATGATGATGTTAAAAACGCAATAGAGAGCAGGATGGGTAAAGTAGAAATGGCTCACGCATAA

Protein

MWRSTLTLLRKIVVPSLKENLQQSKTLFSTKSRPRSTVRLTLISAGIGVLVGAGYGGYTHYKINAKKRTLPQENEEYAFLKQAPKYTPQYCVINDSDTSNLSLVLFQYRTCPFCCKVRAYLDARGISYEVVEVDAVLRQAIKWSGYKKVPIVLAKVDGGYQQLLDSTAIISILETYLLDKKSQLTEIIKFYPVSQFVNDAGKNITEITNKYFIMHNSPLSNDNEKSAELEERKWRQWADTVLVHTLSPNVYRTPGEALETFKWFEQAGRWKESFPGWECALMVYVGAAAMWMIAKRLKKRHNISDDVRQSLYDAANEWTIAVNKKGKRFFGGDAPNLADITVYGVLSSIEGCMAFKDLRNNTQIAKWYDDVKNAIESRMGKVEMAHA

Uniprot

H9ITZ3   A0A2A4IX57   A0A194PFZ0   A0A2H1WE00   A0A212EGK0   A0A386GUM4   + More
A0A194QLE1   A0A0L7L0Y1   A0A2P8YS23   A0A1Q3FC95   A0A0T6B3L2   B0XH58   A0A195EW35   B0WAD6   A0A1Q3FEY0   A0A2J7PW70   F4WHC1   A0A1B6LE27   A0A1B6DD21   A0A1B6ENQ9   A0A151J4D8   A0A067RP32   A0A0K8TMA2   A0A195BRP6   N6T7J1   A0A224XEV5   A0A195D7U8   A0A158NB49   A0A0J7KUT5   A0A1B0EV74   U4U4W5   Q9U5X9   T1I7K6   E1ZYB1   B3NDJ7   Q16XT0   A0A182GTB8   Q9V420   O77287   Q9U5V9   A0A182GEA9   E0W1Y9   A0A0P4VV31   A0A232ESC8   V9IFM3   B4HJQ8   Q9U5V2   A0A084WDX3   A0A0L7QZK0   B4PKC1   A0A023ERH2   A0A154NZS0   A0A1W4UTE6   A0A1Y1N639   A0A1B0DC62   B3M4F9   A0A182QT76   B4QMW2   A0A182J716   A0A336KNX6   A0A1L8E568   B4L9S2   A0A336M778   A0A0M4EMF9   A0A1I8MZU6   A0A1A9XB45   A0A1B0ALJ5   B4LCY4   A0A3Q0IIU2   Q29D53   A0A3B0JYG9   B4J0F0   A0A3L8DNB6   A0A026W2L7   B4N5I3   A0A0A1X8K4   A0A1I8PLL1   A0A0M8ZRH4   A0A1A9URP0   D3TQP0   A0A310SR05   A0A2M4AQ22   A0A1W4W787   A0A1A9W7B1   W8CBR7   A0A034WPR4   A0A182FL89   A0A0K8V803   A0A0K8VE95   E9J013   A0A182XJH3   Q7Q7W1   A0A182HQP3   A0A1B0A6Y6   A0A182KNL5   D6WEJ0   A0A2M4BR36   A0A182PUQ3   A0A182YQQ8   A0A182REP2  

Pubmed

19121390    26354079    22118469    30233407    26227816    29403074    + More
21719571    24845553    26369729    23537049    21347285    20798317    17994087    17510324    26483478    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    20566863    27129103    28648823    24438588    17550304    24945155    28004739    22936249    25315136    15632085    30249741    24508170    25830018    20353571    24495485    25348373    21282665    12364791    14747013    17210077    20966253    18362917    19820115    25244985   

EMBL

BABH01007205    BABH01007206    NWSH01004982    PCG64527.1    KQ459605    KPI91948.1    + More
ODYU01007697    SOQ50714.1    AGBW02015069    OWR40601.1    MG596301    AYD37767.1    KQ461196    KPJ06352.1    JTDY01003812    KOB68971.1    PYGN01000398    PSN47051.1    GFDL01009937    JAV25108.1    LJIG01016156    KRT81447.1    DS233103    EDS28120.1    KQ981953    KYN32361.1    DS231870    EDS41026.1    GFDL01008935    JAV26110.1    NEVH01020938    PNF20570.1    GL888158    EGI66398.1    GEBQ01018048    JAT21929.1    GEDC01013719    JAS23579.1    GECZ01030213    JAS39556.1    KQ980151    KYN17502.1    KK852550    KDR21499.1    GDAI01002337    JAI15266.1    KQ976417    KYM89685.1    APGK01049773    KB741156    ENN73643.1    GFTR01005419    JAW11007.1    KQ976760    KYN08529.1    ADTU01010884    LBMM01003051    KMQ94024.1    AJWK01019416    KB631941    ERL87353.1    AJ250309    CAB58343.1    ACPB03000182    GL435204    EFN73810.1    CH954178    EDV52059.1    CH477533    EAT39424.1    EAT39425.1    JXUM01086779    KQ563590    KXJ73625.1    AE014296    BT044124    AJ250305    AAF49434.1    ACH92189.1    CAB58345.1    AJ011320    AJ250307    CAA09595.1    CAB58349.1    AY070681    AJ250306    AAL48152.1    CAB58347.1    JXUM01057612    KQ561963    KXJ77047.1    DS235873    EEB19583.1    GDKW01001925    JAI54670.1    NNAY01002491    OXU21196.1    JR040761    AEY59281.1    CH480815    EDW41785.1    AJ250308    CAB58355.1    ATLV01023078    KE525340    KFB48417.1    KQ414681    KOC63967.1    CM000159    EDW94819.1    GAPW01001808    JAC11790.1    KQ434786    KZC05169.1    GEZM01012112    JAV93189.1    AJVK01030589    CH902618    EDV40453.1    AXCN02000973    CM000363    CM002912    EDX10754.1    KMZ00084.1    UFQS01000742    UFQT01000742    SSX06526.1    SSX26875.1    GFDF01000379    JAV13705.1    CH933816    EDW17120.1    UFQS01000651    UFQT01000651    SSX05767.1    SSX26126.1    CP012525    ALC44860.1    JXJN01031208    CH940647    EDW68845.1    CH379070    EAL30561.2    OUUW01000012    SPP87127.1    CH916366    EDV96786.1    QOIP01000006    RLU21308.1    KK107494    EZA49836.1    CH964101    EDW79622.1    GBXI01007222    JAD07070.1    KQ435955    KOX68049.1    CCAG010023484    EZ423742    ADD20018.1    KQ761402    OAD57555.1    GGFK01009574    MBW42895.1    GAMC01004601    JAC01955.1    GAKP01001361    JAC57591.1    GDHF01017245    JAI35069.1    GDHF01015070    JAI37244.1    GL767291    EFZ13817.1    AAAB01008948    EAA10500.4    APCN01004672    KQ971318    EFA00341.1    GGFJ01006302    MBW55443.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000053240    UP000037510    + More
UP000245037    UP000002320    UP000078541    UP000235965    UP000007755    UP000078492    UP000027135    UP000078540    UP000019118    UP000078542    UP000005205    UP000036403    UP000092461    UP000030742    UP000015103    UP000000311    UP000008711    UP000008820    UP000069940    UP000249989    UP000000803    UP000009046    UP000215335    UP000001292    UP000030765    UP000053825    UP000002282    UP000076502    UP000192221    UP000092462    UP000007801    UP000075886    UP000000304    UP000075880    UP000009192    UP000092553    UP000095301    UP000092443    UP000092460    UP000008792    UP000079169    UP000001819    UP000268350    UP000001070    UP000279307    UP000053097    UP000007798    UP000095300    UP000053105    UP000078200    UP000092444    UP000192223    UP000091820    UP000069272    UP000076407    UP000007062    UP000075840    UP000092445    UP000075882    UP000007266    UP000075885    UP000076408    UP000075900   

PRIDE

H9ITZ3    Q9V420    O77287    Q9U5V9   

Pfam

PF00462   Glutaredoxin        + More
PF13417   GST_N_3
PF14497   GST_C_3

Interpro

IPR036249   Thioredoxin-like_sf        + More
IPR036282   Glutathione-S-Trfase_C_sf       
IPR034334   PGES2       
IPR034335   PGES2_C       
IPR011767   GLR_AS       
IPR002109   Glutaredoxin       
IPR040079   Glutathione_S-Trfase       
IPR004045   Glutathione_S-Trfase_N       
IPR004046   GST_C       
IPR010987   Glutathione-S-Trfase_C-like       

SUPFAM

SSF47616   SSF47616        + More
SSF52833   SSF52833       

CDD

cd03197  GST_C_mPGES2

ProteinModelPortal

H9ITZ3   A0A2A4IX57   A0A194PFZ0   A0A2H1WE00   A0A212EGK0   A0A386GUM4   + More
A0A194QLE1   A0A0L7L0Y1   A0A2P8YS23   A0A1Q3FC95   A0A0T6B3L2   B0XH58   A0A195EW35   B0WAD6   A0A1Q3FEY0   A0A2J7PW70   F4WHC1   A0A1B6LE27   A0A1B6DD21   A0A1B6ENQ9   A0A151J4D8   A0A067RP32   A0A0K8TMA2   A0A195BRP6   N6T7J1   A0A224XEV5   A0A195D7U8   A0A158NB49   A0A0J7KUT5   A0A1B0EV74   U4U4W5   Q9U5X9   T1I7K6   E1ZYB1   B3NDJ7   Q16XT0   A0A182GTB8   Q9V420   O77287   Q9U5V9   A0A182GEA9   E0W1Y9   A0A0P4VV31   A0A232ESC8   V9IFM3   B4HJQ8   Q9U5V2   A0A084WDX3   A0A0L7QZK0   B4PKC1   A0A023ERH2   A0A154NZS0   A0A1W4UTE6   A0A1Y1N639   A0A1B0DC62   B3M4F9   A0A182QT76   B4QMW2   A0A182J716   A0A336KNX6   A0A1L8E568   B4L9S2   A0A336M778   A0A0M4EMF9   A0A1I8MZU6   A0A1A9XB45   A0A1B0ALJ5   B4LCY4   A0A3Q0IIU2   Q29D53   A0A3B0JYG9   B4J0F0   A0A3L8DNB6   A0A026W2L7   B4N5I3   A0A0A1X8K4   A0A1I8PLL1   A0A0M8ZRH4   A0A1A9URP0   D3TQP0   A0A310SR05   A0A2M4AQ22   A0A1W4W787   A0A1A9W7B1   W8CBR7   A0A034WPR4   A0A182FL89   A0A0K8V803   A0A0K8VE95   E9J013   A0A182XJH3   Q7Q7W1   A0A182HQP3   A0A1B0A6Y6   A0A182KNL5   D6WEJ0   A0A2M4BR36   A0A182PUQ3   A0A182YQQ8   A0A182REP2  

PDB

2PBJ     E-value=2.8926e-72,     Score=691

KEGG

101746997    K05309 microsomal prostaglandin-E synthase 2 [EC:5.3.99.3] | (RefSeq) prostaglandin E synthase 2

PATHWAY

00590    Arachidonic acid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0015035   GO:0009055   GO:0045454   GO:0050220   GO:0005623   GO:0016021   GO:0016740   GO:0003824   GO:0008152   GO:0043401   GO:0003677   GO:0003707   GO:0007169  

Length:

387

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

32.81952

Exp number, first 60 AAs:

20.83782

Total prob of N-in:

0.59417

POSSIBLE N-term signal

sequence

inside

1  -  39

TMhelix

40  -  59

outside

60  -  387

 

 

Pi

4.013695

Theta

14.181716

Tajima's D

-2.006808

CLR

0.96945

CSRT

0.0125493725313734

Interpretation

Uncertain