Gene

KWMTBOMO00391  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000722

Annotation

surfeit_1_isoform_1_[Bombyx_mori]

Location

Bomo_Chr1(+):11509509-11514399      View in EpiBrowser

Full name

SURF1-like protein       + More
Surfeit locus protein 1      

Location in the cell

Mitochondrial   Reliability : 2.173

CDS

ATGATACCAGTTACTTCCTTTACTCTTGGTTCATGGCAAGTGTACAGATGGCAATGGAAGCTGGGGCTCATTGACATGATGCAAGCTAAATCCAATGCTGTCCCAATCGACATGCCAAAAGACTTTTCAGAATTAGAAAAAATGGAATATTTACCAGTGAAAGTAAAAGGAGAATTTTTGCATGAAAAAGAGATATTAATAGGTCCTAGAGCACTCATAGAAGAGAGTTCTATCACCAATAGAGTTGGTTCACTTGTATCTGACCCGAAAAAAAACCAAGGGTGGTTGGTGATCACTCCGTTTAAGTTAGCTGACACAGGAGAAGTCATCTTGATAAACAGAGGTTGGATTCATCAAAATTTAAGGCCTAAAGAAAAGCGAGAGCCATCTTTAATAAAGGGTCCTGTTGAGCTAACTGGTGTTGTAAGGTTAACAGAGAAAAGAGCTCCTTTCATGCCTAAAAATAATCCAGAAAAAGGCTCATGGTTTTACAGAGATTTGGATCAGATGAGTGCTCATATTGGATGTTTGCCGATTTGGTTGGATGCAAAAGGTATCCCAGACCCACCTACTGGTTGGCCGATCCCAAATCAAACCAGAGTAACATTGCGGAATGAACACTTTTCGTACATTGTCACATGGTATTCTTTGTTTGCATTTACTAGTATTATGTGGCATCGTTTCTTCATTAGAAAGTTACCATTATTGTAA

Protein

MIPVTSFTLGSWQVYRWQWKLGLIDMMQAKSNAVPIDMPKDFSELEKMEYLPVKVKGEFLHEKEILIGPRALIEESSITNRVGSLVSDPKKNQGWLVITPFKLADTGEVILINRGWIHQNLRPKEKREPSLIKGPVELTGVVRLTEKRAPFMPKNNPEKGSWFYRDLDQMSAHIGCLPIWLDAKGIPDPPTGWPIPNQTRVTLRNEHFSYIVTWYSLFAFTSIMWHRFFIRKLPLL

Description

Probably involved in the biogenesis of the COX complex.
Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.

Subunit

Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, the core components of this complex being COA3/MITRAC12 and COX14. Interacts with COA3.

Similarity

Belongs to the SURF1 family.

Keywords

Complete proteome   Membrane   Mitochondrion   Mitochondrion inner membrane   Reference proteome   Transmembrane   Transmembrane helix   Alternative splicing   Charcot-Marie-Tooth disease   Disease mutation   Leigh syndrome   Neurodegeneration   Neuropathy   Polymorphism   Primary mitochondrial disease  

Feature

chain  Surfeit locus protein 1
splice variant  In isoform 2.
sequence variant  Found in a patient with LS; unknown pathological significance; dbSNP:rs116779216.

Uniprot

Q2F5K9   H9ITZ2   A0A2H1WY39   A0A194QMZ8   I4DNN9   A0A1E1WLF5   + More
A0A194PF08   S4NP30   A0A212EGI9   A0A0L7LES0   D6WEG3   A0A151J585   K7IR05   A0A3L8DCY0   A0A195C2Q6   A0A154PAC3   A0A195BGH4   A0A158NIH4   A0A026W6D6   F4WK80   E2ATW4   E2BUV8   A0A0L7R3E9   A0A2G9SEB4   A0A067QZH5   A0A2K5I0L5   L7MDX8   A0A2K5I0K2   Q9QXU2   A0A2U3ZRU4   B4KZU3   A0A384DLJ6   A0A091SBE8   A0A0D9RRS6   A0A1Y1LD18   A0A131XJ77   A0A093HAZ2   A0A2K6R453   G3MI75   A0A091NQB0   A0A2K6M7I0   A0A093QY94   F1PFN9   A0A2K5NT40   A0A091FW71   A0A2K6M7G4   A0A2I3LN53   A0A2K6R448   M3YLS3   A0A096P0D0   A0A2K5NSV4   U3JFL1   A0A1B6D123   A0A091GMT9   A0A2Y9E964   D2HF88   A0A2K5V214   F1PFP1   A0A091I4R7   A0A2K6E3A3   A0A1S2ZMC1   A0A2K5YE23   A0A250XYM1   I6L9E0   A0A2A3EBW0   A0A1L8F679   A0A2K5V209   F6ZCK1   I3M2R9   A0A1S3G9A7   A0A2K6E3A5   G7PR91   A0A287D9X5   A0A3L8SDP7   A0A2J8UIY5   A0A2R9A5J1   A0A2P8XTM7   A0A091WCA9   A0A094KHT1   P09925   A0A1V4J649   A0A087RH20   G3I9S2   A0A3L7HDJ2   A0A1W4XSG6   A0A2I3RZJ3   G7NFF9   A0A2R5LHF8   A0A2K6G015   A0A088A2C3   A0A131YU97   A0A1B8Y5A7   H2QY43   A0A224Z9F6   A0A1U8CXU1   G5B8H1   E5KRX5   Q15526   A0A091GQP5  

Pubmed

19121390    26354079    22651552    23622113    22118469    26227816    + More
18362917    19820115    20075255    30249741    21347285    24508170    21719571    20798317    24845553    25576852    10622737    17994087    28004739    28049606    25362486    22216098    16341006    20010809    28087693    15489334    27762356    17431167    25319552    22002653    30282656    22722832    29403074    3025660    16141072    21183079    21804562    29704459    16136131    26830274    20431018    28797301    21993625    20843780    26871637    7702754    14702039    15164053    9843204    11317352    26321642    25944712    10746561    10647889    14564068    16959974    21937992    22410471    22488715    24027061   

EMBL

DQ311414    ABD36358.1    BABH01007203    ODYU01011944    SOQ57979.1    KQ461196    + More
KPJ06350.1    AK403056    BAM19529.1    GDQN01003249    JAT87805.1    KQ459605    KPI91951.1    GAIX01012019    JAA80541.1    AGBW02015069    OWR40599.1    JTDY01001401    KOB73967.1    KQ971318    EFA00352.1    KQ980074    KYN17830.1    QOIP01000010    RLU18166.1    KQ978379    KYM94491.1    KQ434844    KZC08140.1    KQ976491    KYM83317.1    ADTU01016607    ADTU01016608    ADTU01016609    ADTU01016610    ADTU01016611    ADTU01016612    ADTU01016613    KK107374    EZA51578.1    GL888197    EGI65383.1    GL442742    EFN63126.1    GL450772    EFN80495.1    KQ414663    KOC65353.1    KV924374    PIO37833.1    KK853156    KDR10514.1    GACK01002859    JAA62175.1    AF182952    CH933809    EDW17955.2    KK946934    KFQ55160.1    AQIB01148009    GEZM01063898    JAV68927.1    GEFH01002139    JAP66442.1    KL205884    KFV76182.1    JO841576    AEO33193.1    KL390834    KFP91546.1    KL439664    KFW93858.1    AAEX03006771    KK719747    KFO65575.1    AHZZ02007956    AEYP01042389    AGTO01000703    GEDC01017941    JAS19357.1    KL448313    KFO82504.1    ACTA01065156    GL192776    EFB24908.1    AQIA01023131    KL218256    KFP03574.1    GFFV01003560    JAV36385.1    BC052500    AAH52500.1    KZ288311    PBC28531.1    CM004480    OCT67086.1    JSUE03013917    JU323145    JU473633    JV048058    AFE66901.1    AFH30437.1    AFI38129.1    AGTP01090843    CM001290    EHH57007.1    QUSF01000027    RLW00496.1    NDHI03003456    PNJ45241.1    AJFE02078062    PYGN01001366    PSN35363.1    KK733774    KFQ99310.1    KL351004    KFZ58908.1    M14689    AK002469    BC004755    LSYS01008925    OPJ67713.1    KL226358    KFM12774.1    JH001641    EGW06899.1    RAZU01000235    RLQ63946.1    AC195415    GABC01009972    GABF01010317    GABD01004870    NBAG03000232    JAA01366.1    JAA11828.1    JAA28230.1    PNI68719.1    CM001267    EHH23708.1    GGLE01004793    MBY08919.1    GEDV01006831    JAP81726.1    KV460434    OCA18146.1    GFPF01012168    MAA23314.1    JH169003    GEBF01001245    EHB05582.1    JAO02388.1    HQ205786    HQ205787    HQ205788    HQ205789    HQ205790    HQ205791    HQ205792    HQ205793    HQ205794    HQ205795    HQ205796    HQ205797    HQ205798    HQ205799    HQ205800    HQ205801    HQ205802    HQ205803    HQ205804    HQ205805    HQ205806    HQ205807    HQ205808    HQ205809    HQ205810    HQ205811    HQ205812    HQ205813    HQ205814    HQ205815    HQ205816    HQ205817    HQ205818    HQ205819    HQ205820    HQ205821    HQ205822    HQ205823    HQ205824    HQ205825    KU178341    ADP91654.1    ALQ33799.1    Z35093    AK291122    AL158826    BC028314    BC071658    KL507841    KFO85454.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000037510    UP000007266    + More
UP000078492    UP000002358    UP000279307    UP000078542    UP000076502    UP000078540    UP000005205    UP000053097    UP000007755    UP000000311    UP000008237    UP000053825    UP000027135    UP000233080    UP000002494    UP000245340    UP000009192    UP000261680    UP000029965    UP000053584    UP000233200    UP000233180    UP000002254    UP000233060    UP000052976    UP000028761    UP000000715    UP000016665    UP000053760    UP000248480    UP000008912    UP000233100    UP000054308    UP000233120    UP000079721    UP000233140    UP000242457    UP000186698    UP000006718    UP000005215    UP000081671    UP000009130    UP000276834    UP000240080    UP000245037    UP000053605    UP000000589    UP000190648    UP000053286    UP000001075    UP000273346    UP000192223    UP000002277    UP000233160    UP000005203    UP000008143    UP000189706    UP000006813    UP000005640   

PRIDE

Q2F5K9    H9ITZ2    Q9QXU2    P09925    G3I9S2    Q15526    + More

Pfam

PF02104   SURF1

Interpro

IPR002994   Surf1/Shy1       

CDD

cd06662  SURF1

ProteinModelPortal

Q2F5K9   H9ITZ2   A0A2H1WY39   A0A194QMZ8   I4DNN9   A0A1E1WLF5   + More
A0A194PF08   S4NP30   A0A212EGI9   A0A0L7LES0   D6WEG3   A0A151J585   K7IR05   A0A3L8DCY0   A0A195C2Q6   A0A154PAC3   A0A195BGH4   A0A158NIH4   A0A026W6D6   F4WK80   E2ATW4   E2BUV8   A0A0L7R3E9   A0A2G9SEB4   A0A067QZH5   A0A2K5I0L5   L7MDX8   A0A2K5I0K2   Q9QXU2   A0A2U3ZRU4   B4KZU3   A0A384DLJ6   A0A091SBE8   A0A0D9RRS6   A0A1Y1LD18   A0A131XJ77   A0A093HAZ2   A0A2K6R453   G3MI75   A0A091NQB0   A0A2K6M7I0   A0A093QY94   F1PFN9   A0A2K5NT40   A0A091FW71   A0A2K6M7G4   A0A2I3LN53   A0A2K6R448   M3YLS3   A0A096P0D0   A0A2K5NSV4   U3JFL1   A0A1B6D123   A0A091GMT9   A0A2Y9E964   D2HF88   A0A2K5V214   F1PFP1   A0A091I4R7   A0A2K6E3A3   A0A1S2ZMC1   A0A2K5YE23   A0A250XYM1   I6L9E0   A0A2A3EBW0   A0A1L8F679   A0A2K5V209   F6ZCK1   I3M2R9   A0A1S3G9A7   A0A2K6E3A5   G7PR91   A0A287D9X5   A0A3L8SDP7   A0A2J8UIY5   A0A2R9A5J1   A0A2P8XTM7   A0A091WCA9   A0A094KHT1   P09925   A0A1V4J649   A0A087RH20   G3I9S2   A0A3L7HDJ2   A0A1W4XSG6   A0A2I3RZJ3   G7NFF9   A0A2R5LHF8   A0A2K6G015   A0A088A2C3   A0A131YU97   A0A1B8Y5A7   H2QY43   A0A224Z9F6   A0A1U8CXU1   G5B8H1   E5KRX5   Q15526   A0A091GQP5  

KEGG

693110    K14998 surfeit locus 1 family protein | (RefSeq) Surf1; surfeit 1

GO

GO:0005743   GO:0016021   GO:0033617   GO:0004129   GO:0006119   GO:0002168   GO:0042331   GO:0007632   GO:0005739   GO:0055114   GO:0008535   GO:0009060   GO:0005746   GO:0016020   GO:0016208   GO:0019427   GO:0003824   GO:0008152   GO:0043401   GO:0003677   GO:0003707   GO:0007169  

Subcellular location

Mitochondrion inner membrane  

Length:

236

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.17245

Exp number, first 60 AAs:

0.00485

Total prob of N-in:

0.52654

inside

1  -  207

TMhelix

208  -  230

outside

231  -  236

 

 

Pi

22.610906

Theta

27.122785

Tajima's D

-1.009077

CLR

0

CSRT

0.135993200339983

Interpretation

Uncertain