Gene

KWMTBOMO00360

Pre Gene Modal

BGIBMGA000709

Annotation

hypothetical_protein_KGM_10909_[Danaus_plexippus]

Location

Bomo_Chr1(+):10844598-10854515      View in EpiBrowser

Full name

Frequenin-1      

Alternative Name

d-FRQ

Location in the cell

Cytoplasmic   Reliability : 2.659

CDS

ATGTGCAAAGTTACGGAAAAAGAAATTCGGCTTTGGCACAAAGGATTTCTGAAGGACTGCCCCAACGGTCTTCTGACTGAGCAGGGCTTCATAAAGATCTACAAACAATTTTTCCCTCAAGGTGACCCGAGCAAGTTTGCGTCATTGGTGTTCAGAGTGTTTGACGAAAACAATGACGGGTCGATTGAGTTCGAAGAATTCATACGGGCCCTATCGGTGACGTCACGGGGCAATCTAGACGAGAAACTTCACTGGGCTTTCCGTCTCTACGACGTGGACAATGACGGTTACATCACTCGGGATGAAATGTATAACATAGTCGACGCGATCTATCAAATGGTGAATCAAAAACCGAGTTCTGAAAGGTTTGAGTTCAACTCCAAACTTATATTCAAATGCTCATTTCAGGGCCAGACCCCACAGCCTGAGGATGAGAACACTCCCCAGAAGCGCGTCGACAAGATCTTTGACCAGATGGACAAGAACCATGATGACAGGCTGACTCTTGAGGAATTCCGTGAGGGCAGCAAGGCCGACCCCCGCATTGTTCAGGCTCTGTCCCTTGGAGGCGATTAA

Protein

MCKVTEKEIRLWHKGFLKDCPNGLLTEQGFIKIYKQFFPQGDPSKFASLVFRVFDENNDGSIEFEEFIRALSVTSRGNLDEKLHWAFRLYDVDNDGYITRDEMYNIVDAIYQMVNQKPSSERFEFNSKLIFKCSFQGQTPQPEDENTPQKRVDKIFDQMDKNHDDRLTLEEFREGSKADPRIVQALSLGGD

Description

Ca(2+)-dependent modulation of synaptic efficacy.

Miscellaneous

May bind 3 calcium ions via the second, third and fourth EF-hand.

Similarity

Belongs to the recoverin family.

Keywords

Calcium   Complete proteome   Lipoprotein   Membrane   Metal-binding   Myristate   Reference proteome   Repeat  

Feature

chain  Frequenin-1

Uniprot

A0A194PF22   A0A2A4JHS7   A0A2H1VVE6   A0A1Y1M0S7   A0A336KGG1   A0A1S4FM07   + More
A0A2M4CTA3   A0A2M4AZ97   A0A084VGQ3   A0A182RIL1   A0A182QRQ9   A0A182IQ91   A0A182W616   A0A182FJM8   A0A2M4CVZ4   A0A1I8MYC6   A0A1I8Q235   A0A1W4XJE0   A0A3B0KMQ7   Q29G35   B4H7L2   B4MSM4   B4I6P7   B4JXS1   B3NTB4   A0A1W4USF5   B4L321   Q9VWX8   B3MWM1   B4M3A4   B4Q2V3   A0A194QS13   T1PAY1   A0A1B0G5A4   A0A1A9XWQ8   A0A1B0AUJ3   A0A2H8TKK4   A0A2S2NP06   D6WF01   A0A2S2QR16   A0A1B6CHL5   A0A1J1IWT3   B4NTP0   A0A1B6KTB6   A0A158NI29   K7IN11   A0A0L0CK05   A0A1I8NBS7   A0A2J7QMN2   A0A3B0K158   B4H7L3   B4Q2V0   B3MWM3   B4MSM2   B4JXS4   B3NTB1   A0A1W4UQL6   M9PHW6   P37236   A0A0C9R5A7   A0A034VD77   A0A0K8WCY4   A0A2W1BK99   A0A0K8WAE3   A0A034VCK0   A0A0A1WXY6   A0A1B0FC88   A0A0K8U2V0   A0A1A9X5J4   B4NUL7   B4L2X8   A0A3L8D951   W8AYK3   A0A069DWM2   E0VW56   A0A2M3ZK17   A0A164ZTL3   E9GDE5   E2AKT1   F4X100   A0A1B0A5D4   A0A026WV06   A0A0J7LB52   A0A0P6AW60   Q9NB99   A0A1B6JMR2   A0A0A7RNE9   A0A2M3ZDK3   A0A0A1WQ70   A0A154P8X1   H9ITX9   A0A1B0CME2   A0A1B0GQ97   E9IN20   W5JEC1   B0XG62   A0A182MPV7   A0A0M4FAT6   A0A067QLH6   A0A1E1WWQ3  

Pubmed

26354079    28004739    24438588    25315136    15632085    17994087    + More
18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25074811    26109357    26109356    28119500    29966094    17550304    18362917    19820115    21347285    20075255    26108605    8101711    25348373    28756777    25830018    30249741    24495485    26334808    20566863    21292972    20798317    21719571    24508170    10512975    19121390    21282665    20920257    23761445    24845553    28503490   

EMBL

KQ459605    KPI91966.1    NWSH01001531    PCG70952.1    ODYU01004640    SOQ44726.1    + More
GEZM01044406    JAV78250.1    UFQS01000445    UFQT01000445    SSX03996.1    SSX24361.1    GGFL01004379    MBW68557.1    GGFK01012795    MBW46116.1    ATLV01013047    KE524836    KFB37147.1    AXCN02002650    GGFL01005334    MBW69512.1    OUUW01000011    SPP86411.1    CH379065    EAL31394.1    CH479218    EDW33823.1    CH963851    EDW75113.2    CH480823    EDW55995.1    CH916376    EDV95170.1    CH954180    EDV46565.1    CH933810    EDW06949.1    KRF93881.1    KRF93882.1    KRF93883.1    AE014298    BT133347    AAF48809.1    AAS65399.1    AAS65400.1    AFF57512.1    AGB95517.1    CH902625    EDV35006.1    KPU75387.1    CH940651    EDW65279.1    KRF82161.1    KRF82162.1    KRF82163.1    KRF82164.1    CM000162    EDX02687.1    KRK06927.1    KRK06928.1    KQ461196    KPJ06331.1    KA645310    AFP59939.1    CCAG010019898    CCAG010019899    JXJN01003666    GFXV01002860    MBW14665.1    GGMR01006286    MBY18905.1    KQ971319    EFA00309.1    GGMS01011013    MBY80216.1    GEDC01024341    JAS12957.1    CVRI01000063    CRL04560.1    CH983253    EDX16309.1    GEBQ01025295    JAT14682.1    ADTU01016194    ADTU01016195    ADTU01016196    ADTU01016197    ADTU01016198    JRES01000302    KNC32547.1    NEVH01013204    PNF29836.1    SPP86412.1    EDW33824.1    EDX02684.1    EDV35008.1    EDW75111.1    EDV95173.1    EDV46562.2    AGB95515.1    AGB95516.1    L08064    GBYB01007962    GBYB01007963    JAG77729.1    JAG77730.1    GAKP01019434    JAC39518.1    GDHF01028058    GDHF01025528    GDHF01018713    GDHF01003415    JAI24256.1    JAI26786.1    JAI33601.1    JAI48899.1    KZ150032    PZC74711.1    GDHF01004156    JAI48158.1    GAKP01019432    JAC39520.1    GBXI01010942    JAD03350.1    CCAG010010471    CCAG010010472    GDHF01033229    GDHF01031230    JAI19085.1    JAI21084.1    CH984109    EDX16664.1    EDW06945.2    QOIP01000011    RLU16438.1    GAMC01020623    GAMC01020621    GAMC01020619    GAMC01020618    GAMC01020617    JAB85936.1    GBGD01003160    JAC85729.1    DS235817    EEB17612.1    GGFM01008098    MBW28849.1    LRGB01000687    KZS16744.1    GL732540    EFX82492.1    GL440405    EFN65954.1    GL888520    EGI59860.1    KK107111    EZA58939.1    LBMM01000056    KMR05137.1    GDIP01023554    JAM80161.1    AF260780    AAF74284.1    GECU01007182    JAT00525.1    KM523324    AJA36971.1    GGFM01005865    MBW26616.1    GBXI01014299    GBXI01013729    GBXI01013701    GBXI01008116    GBXI01000820    GBXI01000748    JAC99992.1    JAD00563.1    JAD00591.1    JAD06176.1    JAD13472.1    JAD13544.1    KQ434846    KZC08376.1    BABH01007148    AJWK01018611    AJWK01018612    AJVK01006599    AJVK01006600    GL764272    EFZ18043.1    ADMH02001734    ETN61250.1    DS232995    EDS27280.1    AXCM01012451    CP012528    ALC49582.1    KK853183    KDR10143.1    GFAC01007962    JAT91226.1   

Proteomes

UP000053268    UP000218220    UP000030765    UP000075900    UP000075886    UP000075880    + More
UP000075920    UP000069272    UP000095301    UP000095300    UP000192223    UP000268350    UP000001819    UP000008744    UP000007798    UP000001292    UP000001070    UP000008711    UP000192221    UP000009192    UP000000803    UP000007801    UP000008792    UP000002282    UP000053240    UP000092444    UP000092443    UP000092460    UP000007266    UP000183832    UP000000304    UP000005205    UP000002358    UP000037069    UP000235965    UP000091820    UP000279307    UP000009046    UP000076858    UP000000305    UP000000311    UP000007755    UP000092445    UP000053097    UP000036403    UP000076502    UP000005204    UP000092461    UP000092462    UP000000673    UP000002320    UP000075883    UP000092553    UP000027135   

PRIDE

Q9VWX8    M9PHW6    H9ITX9   

Pfam

PF00036   EF-hand_1        + More
PF13499   EF-hand_7
PF13405   EF-hand_6
PF13833   EF-hand_8

Interpro

IPR018247   EF_Hand_1_Ca_BS        + More
IPR002048   EF_hand_dom       
IPR011992   EF-hand-dom_pair       
IPR028846   Recoverin       

SUPFAM

SSF47473   SSF47473       

CDD

cd00051  EFh

ProteinModelPortal

A0A194PF22   A0A2A4JHS7   A0A2H1VVE6   A0A1Y1M0S7   A0A336KGG1   A0A1S4FM07   + More
A0A2M4CTA3   A0A2M4AZ97   A0A084VGQ3   A0A182RIL1   A0A182QRQ9   A0A182IQ91   A0A182W616   A0A182FJM8   A0A2M4CVZ4   A0A1I8MYC6   A0A1I8Q235   A0A1W4XJE0   A0A3B0KMQ7   Q29G35   B4H7L2   B4MSM4   B4I6P7   B4JXS1   B3NTB4   A0A1W4USF5   B4L321   Q9VWX8   B3MWM1   B4M3A4   B4Q2V3   A0A194QS13   T1PAY1   A0A1B0G5A4   A0A1A9XWQ8   A0A1B0AUJ3   A0A2H8TKK4   A0A2S2NP06   D6WF01   A0A2S2QR16   A0A1B6CHL5   A0A1J1IWT3   B4NTP0   A0A1B6KTB6   A0A158NI29   K7IN11   A0A0L0CK05   A0A1I8NBS7   A0A2J7QMN2   A0A3B0K158   B4H7L3   B4Q2V0   B3MWM3   B4MSM2   B4JXS4   B3NTB1   A0A1W4UQL6   M9PHW6   P37236   A0A0C9R5A7   A0A034VD77   A0A0K8WCY4   A0A2W1BK99   A0A0K8WAE3   A0A034VCK0   A0A0A1WXY6   A0A1B0FC88   A0A0K8U2V0   A0A1A9X5J4   B4NUL7   B4L2X8   A0A3L8D951   W8AYK3   A0A069DWM2   E0VW56   A0A2M3ZK17   A0A164ZTL3   E9GDE5   E2AKT1   F4X100   A0A1B0A5D4   A0A026WV06   A0A0J7LB52   A0A0P6AW60   Q9NB99   A0A1B6JMR2   A0A0A7RNE9   A0A2M3ZDK3   A0A0A1WQ70   A0A154P8X1   H9ITX9   A0A1B0CME2   A0A1B0GQ97   E9IN20   W5JEC1   B0XG62   A0A182MPV7   A0A0M4FAT6   A0A067QLH6   A0A1E1WWQ3  

PDB

6EPA     E-value=1.1104e-80,     Score=760

KEGG

101744185    K19932 neuronal calcium sensor 1 | (RefSeq) frequenin-1

GO

GO:0005509   GO:0007528   GO:0046928   GO:0007268   GO:0008021   GO:0007269   GO:0016192   GO:0098793   GO:0008048   GO:0016020   GO:0016021   GO:0043169   GO:0008270   GO:0003676   GO:0030286   GO:0006813   GO:0006810   GO:0009072   GO:0007169  

PANTHER

PTHR23055  

Subcellular location

Membrane  

Length:

191

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00038

Exp number, first 60 AAs:

0.00038

Total prob of N-in:

0.35716

outside

1  -  191

 

 

Pi

1.310335

Theta

1.993597

Tajima's D

0

CLR

0.0826

CSRT

0.410279486025699

Interpretation

Uncertain